메뉴 건너뛰기




Volumn 18, Issue 18, 2012, Pages 2644-2656

Stem cells as a novel tool for drug screening and treatment of degenerative diseases

Author keywords

Adult stem cells; Disease modeling; Drug design; Induced pluripotent stem cells; Organ regeneration; Pluripotent stem cells; Very small embryonic like stem cells

Indexed keywords

ALPHA TOCOTRIENOL; EPIGALLOCATECHIN GALLATE; LEUKEMIA INHIBITORY FACTOR;

EID: 84862551015     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212800492859     Document Type: Review
Times cited : (21)

References (203)
  • 2
    • 79960824615 scopus 로고    scopus 로고
    • Building an integrated neurodegenerative disease database at an academic health center
    • Xie SX, Baek Y, Grossman M, et al. Building an integrated neurodegenerative disease database at an academic health center. Alzheimers Dement 2011; 7: e84-e93.
    • (2011) Alzheimers Dement , vol.7
    • Xie, S.X.1    Baek, Y.2    Grossman, M.3
  • 3
    • 79959728747 scopus 로고    scopus 로고
    • Epidemiology and etiology of Parkinson's disease: A review of the evidence
    • Wirdefeldt K, Adami HO, Cole P, Trichopoulos D, Mandel J. Epidemiology and etiology of Parkinson's disease: a review of the evidence. Eur J Epidemiol 2011; 26 Suppl 1: S1-58.
    • (2011) Eur J Epidemiol , vol.26 , Issue.SUPPL. 1
    • Wirdefeldt, K.1    Adami, H.O.2    Cole, P.3    Trichopoulos, D.4    Mandel, J.5
  • 4
    • 79955774490 scopus 로고    scopus 로고
    • Rate of familial amyotrophic lateral sclerosis: A systematic review and meta-analysis
    • Byrne S, Walsh C, Lynch C, et al. Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis. J Neurol Neurosurg Psychiatry 2011; 82: 623-7.
    • (2011) J Neurol Neurosurg Psychiatry , vol.82 , pp. 623-627
    • Byrne, S.1    Walsh, C.2    Lynch, C.3
  • 5
    • 84862676787 scopus 로고    scopus 로고
    • Cardiac remodeling and subcellular defects in heart failure due to myocardial infarction and aging
    • Dhalla NS, Rangi S, Babick AP, Zieroth S, Elimban V. Cardiac remodeling and subcellular defects in heart failure due to myocardial infarction and aging. Heart Fail Rev 2011.
    • (2011) Heart Fail Rev
    • Dhalla, N.S.1    Rangi, S.2    Babick, A.P.3    Zieroth, S.4    Elimban, V.5
  • 6
    • 33646550833 scopus 로고    scopus 로고
    • Inflammatory and apoptotic signaling after spinal cord injury
    • Keane RW, Davis AR, Dietrich WD. Inflammatory and apoptotic signaling after spinal cord injury. J Neurotrauma 2006; 23: 335-44.
    • (2006) J Neurotrauma , vol.23 , pp. 335-344
    • Keane, R.W.1    Davis, A.R.2    Dietrich, W.D.3
  • 7
    • 59849120171 scopus 로고    scopus 로고
    • Ischemic neuronal damage
    • Taoufik E, Probert L. Ischemic neuronal damage. Curr Pharm Des 2008; 14: 3565-73.
    • (2008) Curr Pharm Des , vol.14 , pp. 3565-3573
    • Taoufik, E.1    Probert, L.2
  • 8
    • 0034306357 scopus 로고    scopus 로고
    • Brain ischemia and reperfusion: Molecular mechanisms of neuronal injury
    • White BC, Sullivan JM, DeGracia DJ, et al. Brain ischemia and reperfusion: molecular mechanisms of neuronal injury. J Neurol Sci 2000; 179: 1-33.
    • (2000) J Neurol Sci , vol.179 , pp. 1-33
    • White, B.C.1    Sullivan, J.M.2    Degracia, D.J.3
  • 9
    • 0035348408 scopus 로고    scopus 로고
    • Neuronal cell death in nervous system development, disease, and injury (Review)
    • Martin LJ. Neuronal cell death in nervous system development, disease, and injury (Review). Int J Mol Med 2001; 7: 455-78.
    • (2001) Int J Mol Med , vol.7 , pp. 455-478
    • Martin, L.J.1
  • 10
    • 54049138387 scopus 로고    scopus 로고
    • Mechanisms of neuronal death in disease: Defining the models and the players
    • Ribe EM, Serrano-Saiz E, Akpan N, Troy CM. Mechanisms of neuronal death in disease: defining the models and the players. Biochem J 2008; 415: 165-82.
    • (2008) Biochem J , vol.415 , pp. 165-182
    • Ribe, E.M.1    Serrano-Saiz, E.2    Akpan, N.3    Troy, C.M.4
  • 11
    • 64749099589 scopus 로고    scopus 로고
    • Optimal medical treatment of cardiovascular risk factors: Can we prevent the development of heart failure?
    • Alba AC, Delgado DH. Optimal medical treatment of cardiovascular risk factors: can we prevent the development of heart failure? Expert Rev Cardiovasc Ther 2009; 7: 147-57.
    • (2009) Expert Rev Cardiovasc Ther , vol.7 , pp. 147-157
    • Alba, A.C.1    Delgado, D.H.2
  • 12
    • 0033838655 scopus 로고    scopus 로고
    • Incidence and epidemiology of heart failure
    • Kannel WB. Incidence and epidemiology of heart failure. Heart Fail Rev 2000; 5: 167-73.
    • (2000) Heart Fail Rev , vol.5 , pp. 167-173
    • Kannel, W.B.1
  • 15
    • 50149098605 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    • Dimos JT, Rodolfa KT, Niakan KK, et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 2008; 321: 1218-21.
    • (2008) Science , vol.321 , pp. 1218-1221
    • Dimos, J.T.1    Rodolfa, K.T.2    Niakan, K.K.3
  • 16
    • 0037133163 scopus 로고    scopus 로고
    • Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model
    • Bjorklund LM, Sanchez-Pernaute R, Chung S, et al. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci USA 2002; 99: 2344-9.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2344-2349
    • Bjorklund, L.M.1    Sanchez-Pernaute, R.2    Chung, S.3
  • 17
    • 0037019332 scopus 로고    scopus 로고
    • Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease
    • Kim JH, Auerbach JM, Rodriguez-Gomez JA, et al. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature 2002; 418: 50-6.
    • (2002) Nature , vol.418 , pp. 50-56
    • Kim, J.H.1    Auerbach, J.M.2    Rodriguez-Gomez, J.A.3
  • 18
    • 3042769428 scopus 로고    scopus 로고
    • Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation
    • Dezawa M, Kanno H, Hoshino M, et al. Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation. J Clin Invest 2004; 113: 1701-10.
    • (2004) J Clin Invest , vol.113 , pp. 1701-1710
    • Dezawa, M.1    Kanno, H.2    Hoshino, M.3
  • 20
    • 78650663606 scopus 로고    scopus 로고
    • Stem cells in cardiac repair
    • Henning RJ. Stem cells in cardiac repair. Future Cardiol 2011; 7: 99-117.
    • (2011) Future Cardiol , vol.7 , pp. 99-117
    • Henning, R.J.1
  • 21
    • 78651368331 scopus 로고    scopus 로고
    • Stem cell therapy for cardiac disease
    • Flynn A, O'Brien T. Stem cell therapy for cardiac disease. Expert Opin Biol Ther 2011; 11: 177-87.
    • (2011) Expert Opin Biol Ther , vol.11 , pp. 177-187
    • Flynn, A.1    O'Brien, T.2
  • 22
    • 67649583797 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stems cells and cardiac repair
    • Chugh AR, Zuba-Surma EK, Dawn B. Bone marrow-derived mesenchymal stems cells and cardiac repair. Minerva Cardioangiol 2009; 57: 185-202.
    • (2009) Minerva Cardioangiol , vol.57 , pp. 185-202
    • Chugh, A.R.1    Zuba-Surma, E.K.2    Dawn, B.3
  • 24
    • 60449117269 scopus 로고    scopus 로고
    • Hepatic stem/progenitor cells and stem-cell transplantation for the treatment of liver disease
    • Kakinuma S, Nakauchi H, Watanabe M. Hepatic stem/progenitor cells and stem-cell transplantation for the treatment of liver disease. J Gastroenterol 2009; 44: 167-72.
    • (2009) J Gastroenterol , vol.44 , pp. 167-172
    • Kakinuma, S.1    Nakauchi, H.2    Watanabe, M.3
  • 25
    • 84862552403 scopus 로고    scopus 로고
    • Potential use of stem cells for kidney regeneration
    • Yokoo T, Matsumoto K, Yokote S. Potential use of stem cells for kidney regeneration. Int J Nephrol 2011; 2011: 591731.
    • (2011) Int J Nephrol , vol.2011 , pp. 591731
    • Yokoo, T.1    Matsumoto, K.2    Yokote, S.3
  • 26
    • 42649130264 scopus 로고    scopus 로고
    • Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
    • Wernig M, Zhao JP, Pruszak J, et al. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci USA 2008; 105: 5856-61.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 5856-5861
    • Wernig, M.1    Zhao, J.P.2    Pruszak, J.3
  • 27
    • 48649104373 scopus 로고    scopus 로고
    • Transplantation of bone marrow- derived very small embryonic-like stem cells attenuates left ventricular dysfunction and remodeling after myocardial infarction
    • Dawn B, Tiwari S, Kucia MJ, et al. Transplantation of bone marrow- derived very small embryonic-like stem cells attenuates left ventricular dysfunction and remodeling after myocardial infarction. Stem Cells 2008; 26: 1646-55.
    • (2008) Stem Cells , vol.26 , pp. 1646-1655
    • Dawn, B.1    Tiwari, S.2    Kucia, M.J.3
  • 28
    • 79957666410 scopus 로고    scopus 로고
    • Transplantation of expanded bone marrow-derived very small embryonic-like stem cells (VSEL-SCs) improves left ventricular function and remodelling after myocardial infarction
    • Zuba-Surma EK, Guo Y, Taher H, et al. Transplantation of expanded bone marrow-derived very small embryonic-like stem cells (VSEL-SCs) improves left ventricular function and remodelling after myocardial infarction. J Cell Mol Med 2011; 15: 1319-28.
    • (2011) J Cell Mol Med , vol.15 , pp. 1319-1328
    • Zuba-Surma, E.K.1    Guo, Y.2    Taher, H.3
  • 29
    • 80052246984 scopus 로고    scopus 로고
    • Modeling neuronal defects associated with a lysosomal disorder using patient-derived induced pluripotent stem cells
    • Lemonnier T, Blanchard S, Toli D, et al. Modeling neuronal defects associated with a lysosomal disorder using patient-derived induced pluripotent stem cells. Hum Mol Genet 2011.
    • (2011) Hum Mol Genet
    • Lemonnier, T.1    Blanchard, S.2    Toli, D.3
  • 30
    • 43449102157 scopus 로고    scopus 로고
    • Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease
    • Bjugstad KB, Teng YD, Redmond DE, Jr., et al. Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease. Exp Neurol 2008; 211: 362-9.
    • (2008) Exp Neurol , vol.211 , pp. 362-369
    • Bjugstad, K.B.1    Teng, Y.D.2    Redmond Jr., D.E.3
  • 31
    • 79956212343 scopus 로고    scopus 로고
    • Constructing and deconstructing stem cell models of neurological disease
    • Han SS, Williams LA, Eggan KC. Constructing and deconstructing stem cell models of neurological disease. Neuron 2011; 70: 626-44.
    • (2011) Neuron , vol.70 , pp. 626-644
    • Han, S.S.1    Williams, L.A.2    Eggan, K.C.3
  • 32
    • 34547913091 scopus 로고    scopus 로고
    • Stem cells: A revolution in therapeutics- recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies
    • Mimeault M, Hauke R, Batra SK. Stem cells: a revolution in therapeutics- recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies. Clin Pharmacol Ther 2007; 82: 252-64.
    • (2007) Clin Pharmacol Ther , vol.82 , pp. 252-264
    • Mimeault, M.1    Hauke, R.2    Batra, S.K.3
  • 33
    • 67849110036 scopus 로고    scopus 로고
    • Stem cells, pluripotency and nuclear reprogramming
    • Jaenisch R. Stem cells, pluripotency and nuclear reprogramming. J Thromb Haemost 2009; 7 Suppl 1: 21-3.
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 1 , pp. 21-23
    • Jaenisch, R.1
  • 35
    • 39149103041 scopus 로고    scopus 로고
    • Hunt for pluripotent stem cell - Regenerative medicine search for almighty cell
    • Ratajczak MZ, Zuba-Surma EK, Wysoczynski M, et al. Hunt for pluripotent stem cell - Regenerative medicine search for almighty cell. J Autoimmun 2008; 30: 151-62.
    • (2008) J Autoimmun , vol.30 , pp. 151-162
    • Ratajczak, M.Z.1    Zuba-Surma, E.K.2    Wysoczynski, M.3
  • 37
    • 77950360753 scopus 로고    scopus 로고
    • Adult stem cells: A clinical update
    • Totey S, Totey S, Pal R, Pal R. Adult stem cells: a clinical update. J Stem Cells 2009; 4: 105-21.
    • (2009) J Stem Cells , vol.4 , pp. 105-121
    • Totey, S.1    Totey, S.2    Pal, R.3    Pal, R.4
  • 38
    • 27944488793 scopus 로고    scopus 로고
    • Adult bone marrow-derived cells: Regenerative potential, plasticity, and tissue commitment
    • Dawn B, Bolli R. Adult bone marrow-derived cells: regenerative potential, plasticity, and tissue commitment. Basic Res Cardiol 2005; 100: 494-503.
    • (2005) Basic Res Cardiol , vol.100 , pp. 494-503
    • Dawn, B.1    Bolli, R.2
  • 39
    • 0015153257 scopus 로고
    • The differentiation of transplanted haematopoietic cells derived from bone marrow, spleen and fetal liver
    • Thomas DB. The differentiation of transplanted haematopoietic cells derived from bone marrow, spleen and fetal liver. J Anat 1971; 110: 297-306.
    • (1971) J Anat , vol.110 , pp. 297-306
    • Thomas, D.B.1
  • 40
    • 47149084386 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of hematopoietic stem cells
    • Ratajczak MZ. Phenotypic and functional characterization of hematopoietic stem cells. Curr Opin Hematol 2008; 15: 293-300.
    • (2008) Curr Opin Hematol , vol.15 , pp. 293-300
    • Ratajczak, M.Z.1
  • 41
    • 0031019745 scopus 로고    scopus 로고
    • Isolation of putative progenitor endothelial cells for angiogenesis
    • Asahara T, Murohara T, Sullivan A, et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997; 275: 964-7.
    • (1997) Science , vol.275 , pp. 964-967
    • Asahara, T.1    Murohara, T.2    Sullivan, A.3
  • 42
    • 0032528555 scopus 로고    scopus 로고
    • Evidence for circulating bone marrow- derived endothelial cells
    • Shi Q, Rafii S, Wu MH, et al. Evidence for circulating bone marrow- derived endothelial cells. Blood 1998; 92: 362-7.
    • (1998) Blood , vol.92 , pp. 362-367
    • Shi, Q.1    Rafii, S.2    Wu, M.H.3
  • 43
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 1997; 276: 71-74.
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 44
    • 1442332442 scopus 로고    scopus 로고
    • Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential
    • Peister A, Mellad JA, Larson BL, Hall BM, Gibson LF, Prockop DJ. Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential. Blood 2004; 103: 1662-8.
    • (2004) Blood , vol.103 , pp. 1662-1668
    • Peister, A.1    Mellad, J.A.2    Larson, B.L.3    Hall, B.M.4    Gibson, L.F.5    Prockop, D.J.6
  • 45
    • 0037019337 scopus 로고    scopus 로고
    • Pluripotency of mesenchymal stem cells derived from adult marrow
    • Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41-9.
    • (2002) Nature , vol.418 , pp. 41-49
    • Jiang, Y.1    Jahagirdar, B.N.2    Reinhardt, R.L.3
  • 46
    • 4344645792 scopus 로고    scopus 로고
    • Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential
    • D'Ippolito G, Diabira S, Howard GA, Menei P, Roos BA, Schiller PC. Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential. J Cell Sci 2004; 117: 2971-81.
    • (2004) J Cell Sci , vol.117 , pp. 2971-2981
    • D'Ippolito, G.1    Diabira, S.2    Howard, G.A.3    Menei, P.4    Roos, B.A.5    Schiller, P.C.6
  • 47
    • 22744444573 scopus 로고    scopus 로고
    • Oocyte generation in adult mammalian ovaries by putative germ cells in bone marrow and peripheral blood
    • Johnson J, Bagley J, Skaznik-Wikiel M, et al. Oocyte generation in adult mammalian ovaries by putative germ cells in bone marrow and peripheral blood. Cell 2005; 122: 303-15.
    • (2005) Cell , vol.122 , pp. 303-315
    • Johnson, J.1    Bagley, J.2    Skaznik-Wikiel, M.3
  • 48
    • 33745154829 scopus 로고    scopus 로고
    • Derivation of male germ cells from bone marrow stem cells
    • Nayernia K, Lee JH, Drusenheimer N, et al. Derivation of male germ cells from bone marrow stem cells. Lab Invest 2006; 86: 654-63.
    • (2006) Lab Invest , vol.86 , pp. 654-663
    • Nayernia, K.1    Lee, J.H.2    Drusenheimer, N.3
  • 49
    • 33646152348 scopus 로고    scopus 로고
    • A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4+ stem cells identified in adult bone marrow
    • Kucia M, Reca R, Campbell FR, et al. A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4+ stem cells identified in adult bone marrow. Leukemia 2006; 20: 857-869.
    • (2006) Leukemia , vol.20 , pp. 857-869
    • Kucia, M.1    Reca, R.2    Campbell, F.R.3
  • 50
    • 50849096689 scopus 로고    scopus 로고
    • Very Small Embryonic-Like (VSEL) Stem Cells: Purification from Adult Organs, Characterization, and Biological Significance
    • Ratajczak MZ, Zuba-Surma EK, Machalinski B, Ratajczak J, Kucia M. Very Small Embryonic-Like (VSEL) Stem Cells: Purification from Adult Organs, Characterization, and Biological Significance. Stem Cell Rev 2008; 4: 89-99.
    • (2008) Stem Cell Rev , vol.4 , pp. 89-99
    • Ratajczak, M.Z.1    Zuba-Surma, E.K.2    Machalinski, B.3    Ratajczak, J.4    Kucia, M.5
  • 51
    • 72449147311 scopus 로고    scopus 로고
    • Optimization of isolation and further characterization of umbilical-cord-blood-derived very small embryonic/ epiblast- like stem cells (VSELs)
    • Zuba-Surma EK, Klich I, Greco N, Laughlin MJ, Ratajczak J, Ratajczak MZ. Optimization of isolation and further characterization of umbilical-cord-blood-derived very small embryonic/ epiblast- like stem cells (VSELs). Eur J Haematol 2010; 84: 34-46.
    • (2010) Eur J Haematol , vol.84 , pp. 34-46
    • Zuba-Surma, E.K.1    Klich, I.2    Greco, N.3    Laughlin, M.J.4    Ratajczak, J.5    Ratajczak, M.Z.6
  • 52
    • 3242755834 scopus 로고    scopus 로고
    • A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential
    • Kogler G, Sensken S, Airey JA, et al. A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential. J Exp Med 2004; 200: 123-35.
    • (2004) J Exp Med , vol.200 , pp. 123-135
    • Kogler, G.1    Sensken, S.2    Airey, J.A.3
  • 53
    • 78649343271 scopus 로고    scopus 로고
    • Lentiviral labeling reveals three germ layer differentiation potential of a single unrestricted somatic stem cell from human cord blood
    • Wernet P, Trapp T, Zweigerdt R, Mann J, Trompeter HI. Lentiviral labeling reveals three germ layer differentiation potential of a single unrestricted somatic stem cell from human cord blood. Exp Hematol 2010; 38: 1099-104.
    • (2010) Exp Hematol , vol.38 , pp. 1099-1104
    • Wernet, P.1    Trapp, T.2    Zweigerdt, R.3    Mann, J.4    Trompeter, H.I.5
  • 54
    • 33644886641 scopus 로고    scopus 로고
    • Neural stem-like cell line derived from a nonhematopoietic population of human umbilical cord blood
    • Buzanska L, Jurga M, Stachowiak EK, Stachowiak MK, Domanska-Janik K. Neural stem-like cell line derived from a nonhematopoietic population of human umbilical cord blood. Stem Cells Dev 2006; 15: 391-406.
    • (2006) Stem Cells Dev , vol.15 , pp. 391-406
    • Buzanska, L.1    Jurga, M.2    Stachowiak, E.K.3    Stachowiak, M.K.4    Domanska-Janik, K.5
  • 55
  • 56
    • 33846487365 scopus 로고    scopus 로고
    • Morphological and molecular characterization of novel population of CXCR4(+) SSEA-4(+) Oct-4(+) very small embryonic-like cells purified from human cord blood - preliminary report
    • Kucia M, Halasa M, Wysoczynski M, et al. Morphological and molecular characterization of novel population of CXCR4(+) SSEA-4(+) Oct-4(+) very small embryonic-like cells purified from human cord blood - preliminary report. Leukemia 2007; 21: 297-303.
    • (2007) Leukemia , vol.21 , pp. 297-303
    • Kucia, M.1    Halasa, M.2    Wysoczynski, M.3
  • 57
    • 23844523442 scopus 로고    scopus 로고
    • Production of stem cells with embryonic characteristics from human umbilical cord blood
    • McGuckin CP, Forraz N, Baradez MO, et al. Production of stem cells with embryonic characteristics from human umbilical cord blood. Cell Prolif 2005; 38: 245-55.
    • (2005) Cell Prolif , vol.38 , pp. 245-255
    • McGuckin, C.P.1    Forraz, N.2    Baradez, M.O.3
  • 58
    • 0025981591 scopus 로고
    • Isolation, culture and characterisation of fibroblast-like cells derived from the Wharton's jelly portion of human umbilical cord
    • McElreavey KD, Irvine AI, Ennis KT, McLean WH. Isolation, culture and characterisation of fibroblast-like cells derived from the Wharton's jelly portion of human umbilical cord. Biochem Soc Trans 1991; 19: 29S.
    • (1991) Biochem Soc Trans , vol.19
    • McElreavey, K.D.1    Irvine, A.I.2    Ennis, K.T.3    McLean, W.H.4
  • 59
    • 77955093312 scopus 로고    scopus 로고
    • The umbilical cord matrix is a better source of mesenchymal stem cells (MSC) than the umbilical cord blood
    • Zeddou M, Briquet A, Relic B, et al. The umbilical cord matrix is a better source of mesenchymal stem cells (MSC) than the umbilical cord blood. Cell Biol Int 2010; 34: 693-701.
    • (2010) Cell Biol Int , vol.34 , pp. 693-701
    • Zeddou, M.1    Briquet, A.2    Relic, B.3
  • 60
    • 65349129408 scopus 로고    scopus 로고
    • Oct-4A isoform is expressed in human cord blood-derived CD133 stem cells and differentiated progeny
    • Howe M, Zhao J, Bodenburg Y, et al. Oct-4A isoform is expressed in human cord blood-derived CD133 stem cells and differentiated progeny. Cell Prolif 2009; 42: 265-75.
    • (2009) Cell Prolif , vol.42 , pp. 265-275
    • Howe, M.1    Zhao, J.2    Bodenburg, Y.3
  • 61
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-76.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 62
    • 34249863603 scopus 로고    scopus 로고
    • Strategies and new developments in the generation of patient-specific pluripotent stem cells
    • Yamanaka S. Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell 2007; 1: 39-49.
    • (2007) Cell Stem Cell , vol.1 , pp. 39-49
    • Yamanaka, S.1
  • 63
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318: 1917-20.
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 64
    • 56749183935 scopus 로고    scopus 로고
    • Very small embryoniclike stem cells are present in adult murine organs: ImageStreambased morphological analysis and distribution studies
    • Zuba-Surma EK, Kucia M, Wu W, et al. Very small embryoniclike stem cells are present in adult murine organs: ImageStreambased morphological analysis and distribution studies. Cytometry A 2008; 73A: 1116-27.
    • (2008) Cytometry A , vol.73 A , pp. 1116-1127
    • Zuba-Surma, E.K.1    Kucia, M.2    Wu, W.3
  • 65
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981; 292: 154-6.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 66
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282: 1145-7.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 67
    • 34447295350 scopus 로고    scopus 로고
    • Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
    • Adewumi O, Aflatoonian B, Ahrlund-Richter L, et al. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol 2007; 25: 803-16.
    • (2007) Nat Biotechnol , vol.25 , pp. 803-816
    • Adewumi, O.1    Aflatoonian, B.2    Ahrlund-Richter, L.3
  • 68
    • 39649111114 scopus 로고    scopus 로고
    • Intracellular signaling pathways regulating pluripotency of embryonic stem cells
    • Okita K, Yamanaka S. Intracellular signaling pathways regulating pluripotency of embryonic stem cells. Curr Stem Cell Res Ther 2006; 1: 103-11.
    • (2006) Curr Stem Cell Res Ther , vol.1 , pp. 103-111
    • Okita, K.1    Yamanaka, S.2
  • 69
    • 0347004677 scopus 로고    scopus 로고
    • Human embryonic stem cells: Multilineage differentiation and mechanisms of self-renewal
    • Draper JS, Fox V. Human embryonic stem cells: multilineage differentiation and mechanisms of self-renewal. Arch Med Res 2003; 34: 558-64.
    • (2003) Arch Med Res , vol.34 , pp. 558-564
    • Draper, J.S.1    Fox, V.2
  • 70
    • 59749089913 scopus 로고    scopus 로고
    • Derivation and manipulation of murine embryonic stem cells
    • Meissner A, Eminli S, Jaenisch R. Derivation and manipulation of murine embryonic stem cells. Methods Mol Biol 2009; 482: 3-19.
    • (2009) Methods Mol Biol , vol.482 , pp. 3-19
    • Meissner, A.1    Eminli, S.2    Jaenisch, R.3
  • 71
    • 43049138057 scopus 로고    scopus 로고
    • Whole-blastocyst culture followed by laser drilling technology enhances the efficiency of inner cell mass isolation and embryonic stem cell derivation from good- and poor-quality mouse embryos: New insights for derivation of human embryonic stem cell lines
    • Cortes JL, Sanchez L, Catalina P, et al. Whole-blastocyst culture followed by laser drilling technology enhances the efficiency of inner cell mass isolation and embryonic stem cell derivation from good- and poor-quality mouse embryos: new insights for derivation of human embryonic stem cell lines. Stem Cells Dev 2008; 17: 255-67.
    • (2008) Stem Cells Dev , vol.17 , pp. 255-267
    • Cortes, J.L.1    Sanchez, L.2    Catalina, P.3
  • 72
    • 34249876564 scopus 로고    scopus 로고
    • Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
    • Masui S, Nakatake Y, Toyooka Y, et al. Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol 2007; 9: 625-35.
    • (2007) Nat Cell Biol , vol.9 , pp. 625-635
    • Masui, S.1    Nakatake, Y.2    Toyooka, Y.3
  • 73
    • 21444432424 scopus 로고    scopus 로고
    • Animal embryonic stem (ES) cells: Self-renewal, pluripotency, transgenesis and nuclear transfer
    • Saito S, Liu B, Yokoyama K. Animal embryonic stem (ES) cells: self-renewal, pluripotency, transgenesis and nuclear transfer. Hum Cell 2004; 17: 107-15.
    • (2004) Hum Cell , vol.17 , pp. 107-115
    • Saito, S.1    Liu, B.2    Yokoyama, K.3
  • 74
    • 73049105546 scopus 로고    scopus 로고
    • Modeling disease in human ESCs using an efficient BAC-based homologous recombination system
    • Song H, Chung SK, Xu Y. Modeling disease in human ESCs using an efficient BAC-based homologous recombination system. Cell Stem Cell 2010; 6: 80-9.
    • (2010) Cell Stem Cell , vol.6 , pp. 80-89
    • Song, H.1    Chung, S.K.2    Xu, Y.3
  • 75
    • 33745222812 scopus 로고    scopus 로고
    • Human embryonic stem cells as a cellular model for human disorders
    • Friedrich Ben-Nun I, Benvenisty N. Human embryonic stem cells as a cellular model for human disorders. Mol Cell Endocrinol 2006; 252: 154-9.
    • (2006) Mol Cell Endocrinol , vol.252 , pp. 154-159
    • Ben-Nun, I.F.1    Benvenisty, N.2
  • 76
    • 67650386543 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cell lines from Tibetan miniature pig
    • Esteban MA, Xu J, Yang J, et al. Generation of induced pluripotent stem cell lines from Tibetan miniature pig. J Biol Chem 2009; 284: 17634-40.
    • (2009) J Biol Chem , vol.284 , pp. 17634-17640
    • Esteban, M.A.1    Xu, J.2    Yang, J.3
  • 77
    • 56549121405 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts
    • Liu H, Zhu F, Yong J, et al. Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. Cell Stem Cell 2008; 3: 587-90.
    • (2008) Cell Stem Cell , vol.3 , pp. 587-590
    • Liu, H.1    Zhu, F.2    Yong, J.3
  • 78
    • 77955931659 scopus 로고    scopus 로고
    • Generating induced pluripotent stem cells from common marmoset (Callithrix jacchus) fetal liver cells using defined factors, including Lin28
    • Tomioka I, Maeda T, Shimada H, et al. Generating induced pluripotent stem cells from common marmoset (Callithrix jacchus) fetal liver cells using defined factors, including Lin28. Genes Cells 2010; 15: 959-69.
    • (2010) Genes Cells , vol.15 , pp. 959-969
    • Tomioka, I.1    Maeda, T.2    Shimada, H.3
  • 79
    • 48749109823 scopus 로고    scopus 로고
    • Pluripotent stem cell lines
    • Yu J, Thomson JA. Pluripotent stem cell lines. Genes Dev 2008; 22: 1987-97.
    • (2008) Genes Dev , vol.22 , pp. 1987-1997
    • Yu, J.1    Thomson, J.A.2
  • 80
    • 69949104478 scopus 로고    scopus 로고
    • Adult mice generated from induced pluripotent stem cells
    • Boland MJ, Hazen JL, Nazor KL, et al. Adult mice generated from induced pluripotent stem cells. Nature 2009; 461: 91-4.
    • (2009) Nature , vol.461 , pp. 91-94
    • Boland, M.J.1    Hazen, J.L.2    Nazor, K.L.3
  • 81
    • 69949089630 scopus 로고    scopus 로고
    • iPS cells produce viable mice through tetraploid complementation
    • Zhao XY, Li W, Lv Z, et al. iPS cells produce viable mice through tetraploid complementation. Nature 2009; 461: 86-90.
    • (2009) Nature , vol.461 , pp. 86-90
    • Zhao, X.Y.1    Li, W.2    Lv, Z.3
  • 82
    • 79952614332 scopus 로고    scopus 로고
    • Cardiac tumorigenic potential of induced pluripotent stem cells in an immunocompetent host with myocardial infarction
    • Ahmed RP, Ashraf M, Buccini S, Shujia J, Haider H. Cardiac tumorigenic potential of induced pluripotent stem cells in an immunocompetent host with myocardial infarction. Regen Med 2011; 6: 171-8.
    • (2011) Regen Med , vol.6 , pp. 171-178
    • Ahmed, R.P.1    Ashraf, M.2    Buccini, S.3    Shujia, J.4    Haider, H.5
  • 83
    • 79957807595 scopus 로고    scopus 로고
    • Immunogenicity of induced pluripotent stem cells
    • Zhao T, Zhang ZN, Rong Z, Xu Y. Immunogenicity of induced pluripotent stem cells. Nature 2011; 474: 212-5.
    • (2011) Nature , vol.474 , pp. 212-215
    • Zhao, T.1    Zhang, Z.N.2    Rong, Z.3    Xu, Y.4
  • 84
    • 71049168277 scopus 로고    scopus 로고
    • Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules
    • Dressel R, Guan K, Nolte J, et al. Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules. Biol Direct 2009; 4: 31.
    • (2009) Biol Direct , vol.4 , pp. 31
    • Dressel, R.1    Guan, K.2    Nolte, J.3
  • 85
    • 36148960428 scopus 로고    scopus 로고
    • Reprogramming somatic cells towards pluripotency by defined factors
    • Lewitzky M, Yamanaka S. Reprogramming somatic cells towards pluripotency by defined factors. Curr Opin Biotechnol 2007; 18: 467-73.
    • (2007) Curr Opin Biotechnol , vol.18 , pp. 467-473
    • Lewitzky, M.1    Yamanaka, S.2
  • 86
    • 79958264182 scopus 로고    scopus 로고
    • Cell fate plug and play: Direct reprogramming and induced pluripotency
    • Chambers SM, Studer L. Cell fate plug and play: direct reprogramming and induced pluripotency. Cell 2011; 145: 827-30.
    • (2011) Cell , vol.145 , pp. 827-830
    • Chambers, S.M.1    Studer, L.2
  • 87
    • 79952846468 scopus 로고    scopus 로고
    • Progress in understanding reprogramming to the induced pluripotent state
    • Plath K, Lowry WE. Progress in understanding reprogramming to the induced pluripotent state. Nat Rev Genet 2011; 12: 253-65.
    • (2011) Nat Rev Genet , vol.12 , pp. 253-265
    • Plath, K.1    Lowry, W.E.2
  • 88
    • 78149487692 scopus 로고    scopus 로고
    • Pluripotency and cellular reprogramming: Facts, hypotheses, unresolved issues
    • Hanna JH, Saha K, Jaenisch R. Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell 2011; 143: 508-25.
    • (2011) Cell , vol.143 , pp. 508-525
    • Hanna, J.H.1    Saha, K.2    Jaenisch, R.3
  • 89
    • 67349204472 scopus 로고    scopus 로고
    • Repair of tissues by adult stem/progenitor cells (MSCs): Controversies, myths, and changing paradigms
    • Prockop DJ. Repair of tissues by adult stem/progenitor cells (MSCs): controversies, myths, and changing paradigms. Mol Ther 2009; 17: 939-46.
    • (2009) Mol Ther , vol.17 , pp. 939-946
    • Prockop, D.J.1
  • 90
    • 41149161751 scopus 로고    scopus 로고
    • Morphological characterization of very small embryonic-like stem cells (VSELs) by ImageStream system analysis
    • Zuba-Surma EK, Kucia M, Abdel-Latif A, et al. Morphological characterization of very small embryonic-like stem cells (VSELs) by ImageStream system analysis. J Cell Mol Med 2008; 12: 292-303.
    • (2008) J Cell Mol Med , vol.12 , pp. 292-303
    • Zuba-Surma, E.K.1    Kucia, M.2    Abdel-Latif, A.3
  • 91
    • 70349817812 scopus 로고    scopus 로고
    • Fetal liver very small embryonic/ epiblast like stem cells follow developmental migratory pathway of hematopoietic stem cells
    • Zuba-Surma EK, Kucia M, Rui L, et al. Fetal liver very small embryonic/ epiblast like stem cells follow developmental migratory pathway of hematopoietic stem cells. Ann N Y Acad Sci 2009; 1176: 205-18.
    • (2009) Ann N Y Acad Sci , vol.1176 , pp. 205-218
    • Zuba-Surma, E.K.1    Kucia, M.2    Rui, L.3
  • 92
    • 68549087167 scopus 로고    scopus 로고
    • Identification of small Sca- 1(+), Lin(-), CD45(-) multipotential cells in the neonatal murine retina
    • Liu Y, Gao L, Zuba-Surma EK, et al. Identification of small Sca- 1(+), Lin(-), CD45(-) multipotential cells in the neonatal murine retina. Exp Hematol 2009; 37: 1096-107, 1107 e1.
    • (2009) Exp Hematol , vol.37
    • Liu, Y.1    Gao, L.2    Zuba-Surma, E.K.3
  • 93
    • 80051499572 scopus 로고    scopus 로고
    • Detection, characterization, and spontaneous differentiation in vitro of very small embryonic-like putative stem cells in adult Mammalian ovary
    • Parte S, Bhartiya D, Telang J, et al. Detection, characterization, and spontaneous differentiation in vitro of very small embryonic-like putative stem cells in adult Mammalian ovary. Stem Cells Dev 2011; 20: 1451-64.
    • (2011) Stem Cells Dev , vol.20 , pp. 1451-1464
    • Parte, S.1    Bhartiya, D.2    Telang, J.3
  • 94
    • 80051802410 scopus 로고    scopus 로고
    • Hematopoietic differentiation of umbilical cord blood-derived very small embryonic/ epiblast-like stem cells
    • Ratajczak J, Zuba-Surma E, Klich I, et al. Hematopoietic differentiation of umbilical cord blood-derived very small embryonic/ epiblast-like stem cells. Leukemia 2011; 25: 1278-85.
    • (2011) Leukemia , vol.25 , pp. 1278-1285
    • Ratajczak, J.1    Zuba-Surma, E.2    Klich, I.3
  • 95
    • 57849169472 scopus 로고    scopus 로고
    • Mobilization of bone marrow-derived Oct-4+ SSEA-4+ very small embryonic-like stem cells in patients with acute myocardial infarction
    • Wojakowski W, Tendera M, Kucia M, et al. Mobilization of bone marrow-derived Oct-4+ SSEA-4+ very small embryonic-like stem cells in patients with acute myocardial infarction. J Am Coll Cardiol 2009; 53: 1-9.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1-9
    • Wojakowski, W.1    Tendera, M.2    Kucia, M.3
  • 96
    • 80053258048 scopus 로고    scopus 로고
    • Stem Cells, Including a Population of Very Small Embryonic-Like Stem Cells, are Mobilized Into Peripheral Blood in Patients After Skin Burn Injury
    • Drukala J, Paczkowska E, Kucia M, et al. Stem Cells, Including a Population of Very Small Embryonic-Like Stem Cells, are Mobilized Into Peripheral Blood in Patients After Skin Burn Injury. Stem Cell Rev 2011.
    • (2011) Stem Cell Rev
    • Drukala, J.1    Paczkowska, E.2    Kucia, M.3
  • 97
    • 79952701456 scopus 로고    scopus 로고
    • Identification and isolation from either adult human bone marrow or G-CSF-mobilized peripheral blood of CD34(+)/CD133(+)/CXCR4(+)/ Lin(-)CD45(-) cells, featuring morphological, molecular, and phenotypic characteristics of very small embryonic-like (VSEL) stem cells
    • Sovalat H, Scrofani M, Eidenschenk A, Pasquet S, Rimelen V, Henon P. Identification and isolation from either adult human bone marrow or G-CSF-mobilized peripheral blood of CD34(+)/CD133(+)/CXCR4(+)/ Lin(-)CD45(-) cells, featuring morphological, molecular, and phenotypic characteristics of very small embryonic-like (VSEL) stem cells. Exp Hematol 2011; 39: 495-505.
    • (2011) Exp Hematol , vol.39 , pp. 495-505
    • Sovalat, H.1    Scrofani, M.2    Eidenschenk, A.3    Pasquet, S.4    Rimelen, V.5    Henon, P.6
  • 98
    • 65249152405 scopus 로고    scopus 로고
    • Clinical evidence that very small embryonic-like stem cells are mobilized into peripheral blood in patients after stroke
    • Paczkowska E, Kucia M, Koziarska D, et al. Clinical evidence that very small embryonic-like stem cells are mobilized into peripheral blood in patients after stroke. Stroke 2009; 40: 1237-44.
    • (2009) Stroke , vol.40 , pp. 1237-1244
    • Paczkowska, E.1    Kucia, M.2    Koziarska, D.3
  • 99
    • 0742306878 scopus 로고    scopus 로고
    • Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow
    • Ratajczak MZ, Kucia M, Reca R, Majka M, Janowska-Wieczorek A, Ratajczak J. Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow. Leukemia 2004; 18: 29-40.
    • (2004) Leukemia , vol.18 , pp. 29-40
    • Ratajczak, M.Z.1    Kucia, M.2    Reca, R.3    Majka, M.4    Janowska-Wieczorek, A.5    Ratajczak, J.6
  • 100
    • 44949179560 scopus 로고    scopus 로고
    • Culture of embryonic- like stem cells from human umbilical cord blood and onward differentiation to neural cells in vitro
    • McGuckin C, Jurga M, Ali H, Strbad M, Forraz N. Culture of embryonic- like stem cells from human umbilical cord blood and onward differentiation to neural cells in vitro. Nat Protoc 2008; 3: 1046-55.
    • (2008) Nat Protoc , vol.3 , pp. 1046-1055
    • McGuckin, C.1    Jurga, M.2    Ali, H.3    Strbad, M.4    Forraz, N.5
  • 101
    • 34249019166 scopus 로고    scopus 로고
    • Directed engineering of umbilical cord blood stem cells to produce C-peptide and insulin
    • Denner L, Bodenburg Y, Zhao JG, et al. Directed engineering of umbilical cord blood stem cells to produce C-peptide and insulin. Cell Prolif 2007; 40: 367-80.
    • (2007) Cell Prolif , vol.40 , pp. 367-380
    • Denner, L.1    Bodenburg, Y.2    Zhao, J.G.3
  • 102
    • 79960982126 scopus 로고    scopus 로고
    • Human neural crestderived postnatal cells exhibit remarkable embryonic attributes either in vitro or in vivo
    • d'Aquino R, Tirino V, Desiderio V, et al. Human neural crestderived postnatal cells exhibit remarkable embryonic attributes either in vitro or in vivo. Eur Cell Mater 2011; 21: 304-16.
    • (2011) Eur Cell Mater , vol.21 , pp. 304-316
    • d'Aquino, R.1    Tirino, V.2    Desiderio, V.3
  • 103
    • 41049096751 scopus 로고    scopus 로고
    • Stromal cells cultured from omentum express pluripotent markers, produce high amounts of VEGF, and engraft to injured sites
    • Singh AK, Patel J, Litbarg NO, et al. Stromal cells cultured from omentum express pluripotent markers, produce high amounts of VEGF, and engraft to injured sites. Cell Tissue Res 2008; 332: 81-8.
    • (2008) Cell Tissue Res , vol.332 , pp. 81-88
    • Singh, A.K.1    Patel, J.2    Litbarg, N.O.3
  • 104
    • 33846653546 scopus 로고    scopus 로고
    • Development of adult pluripotent stem cell therapies for ischemic injury and disease
    • Mays RW, van't Hof W, Ting AE, Perry R, Deans R. Development of adult pluripotent stem cell therapies for ischemic injury and disease. Expert Opin Biol Ther 2007; 7: 173-84.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 173-184
    • Mays, R.W.1    van't Hof, W.2    Ting, A.E.3    Perry, R.4    Deans, R.5
  • 105
    • 79952817038 scopus 로고    scopus 로고
    • Expression pattern of Oct-4, Sox2, and c-Myc in the primary culture of human dental pulp derived cells
    • Liu L, Wei X, Ling J, Wu L, Xiao Y. Expression pattern of Oct-4, Sox2, and c-Myc in the primary culture of human dental pulp derived cells. J Endod 2011; 37: 466-72.
    • (2011) J Endod , vol.37 , pp. 466-472
    • Liu, L.1    Wei, X.2    Ling, J.3    Wu, L.4    Xiao, Y.5
  • 106
    • 77956557074 scopus 로고    scopus 로고
    • Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled- 9 receptor in human periodontal ligament mesenchymal stem cells
    • Trubiani O, Zalzal SF, Paganelli R, et al. Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled- 9 receptor in human periodontal ligament mesenchymal stem cells. J Cell Physiol 2010; 225: 123-31.
    • (2010) J Cell Physiol , vol.225 , pp. 123-131
    • Trubiani, O.1    Zalzal, S.F.2    Paganelli, R.3
  • 107
    • 67649657795 scopus 로고    scopus 로고
    • Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: Results of randomized, multicentre Myocardial Regeneration by Intracoronary Infusion of Selected Population of Stem Cells in Acute Myocardial Infarction (REGENT) Trial
    • Tendera M, Wojakowski W, Ruzyllo W, et al. Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Intracoronary Infusion of Selected Population of Stem Cells in Acute Myocardial Infarction (REGENT) Trial. Eur Heart J 2009; 30: 1313-21.
    • (2009) Eur Heart J , vol.30 , pp. 1313-1321
    • Tendera, M.1    Wojakowski, W.2    Ruzyllo, W.3
  • 108
    • 79955377793 scopus 로고    scopus 로고
    • Systemic treatment of focal brain injury in the rat by human umbilical cord blood cells being at different level of neural commitment
    • Gornicka-Pawlak el B, Janowski M, Habich A, et al. Systemic treatment of focal brain injury in the rat by human umbilical cord blood cells being at different level of neural commitment. Acta Neurobiol Exp (Wars) 2011; 71: 46-64.
    • (2011) Acta Neurobiol Exp (Wars) , vol.71 , pp. 46-64
    • el Gornicka-Pawlak, B.1    Janowski, M.2    Habich, A.3
  • 113
    • 39749132884 scopus 로고    scopus 로고
    • Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease
    • O'Keeffe FE, Scott SA, Tyers P, et al. Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease. Brain 2008; 131: 630-41.
    • (2008) Brain , vol.131 , pp. 630-641
    • O'Keeffe, F.E.1    Scott, S.A.2    Tyers, P.3
  • 114
    • 38149126482 scopus 로고    scopus 로고
    • Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice
    • Parish CL, Castelo-Branco G, Rawal N, et al. Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice. J Clin Invest 2008; 118: 149-60.
    • (2008) J Clin Invest , vol.118 , pp. 149-160
    • Parish, C.L.1    Castelo-Branco, G.2    Rawal, N.3
  • 116
    • 33644684826 scopus 로고    scopus 로고
    • Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
    • Studer L, Tabar V, McKay RD. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci 1998; 1: 290-5.
    • (1998) Nat Neurosci , vol.1 , pp. 290-295
    • Studer, L.1    Tabar, V.2    McKay, R.D.3
  • 117
    • 34247629489 scopus 로고    scopus 로고
    • Generation of functional dopamine neurons from neural precursor cells isolated from the subventricular zone and white matter of the adult rat brain using Nurr1 overexpression
    • Shim JW, Park CH, Bae YC, et al. Generation of functional dopamine neurons from neural precursor cells isolated from the subventricular zone and white matter of the adult rat brain using Nurr1 overexpression. Stem Cells 2007; 25: 1252-62.
    • (2007) Stem Cells , vol.25 , pp. 1252-1262
    • Shim, J.W.1    Park, C.H.2    Bae, Y.C.3
  • 118
    • 55049138293 scopus 로고    scopus 로고
    • Directed evolution of motor neurons from genetically engineered neural precursors
    • Bohl D, Liu S, Blanchard S, Hocquemiller M, Haase G, Heard JM. Directed evolution of motor neurons from genetically engineered neural precursors. Stem Cells 2008; 26: 2564-75.
    • (2008) Stem Cells , vol.26 , pp. 2564-2575
    • Bohl, D.1    Liu, S.2    Blanchard, S.3    Hocquemiller, M.4    Haase, G.5    Heard, J.M.6
  • 119
    • 62849108746 scopus 로고    scopus 로고
    • Generation of spinal motor neurons from human fetal brain-derived neural stem cells: Role of basic fibroblast growth factor
    • Jordan PM, Ojeda LD, Thonhoff JR, et al. Generation of spinal motor neurons from human fetal brain-derived neural stem cells: role of basic fibroblast growth factor. J Neurosci Res 2009; 87: 318-32.
    • (2009) J Neurosci Res , vol.87 , pp. 318-332
    • Jordan, P.M.1    Ojeda, L.D.2    Thonhoff, J.R.3
  • 120
    • 0034717016 scopus 로고    scopus 로고
    • Human umbilical cord blood effect on sod mice (amyotrophic lateral sclerosis)
    • Ende N, Weinstein F, Chen R, Ende M. Human umbilical cord blood effect on sod mice (amyotrophic lateral sclerosis). Life Sci 2000; 67: 53-9.
    • (2000) Life Sci , vol.67 , pp. 53-59
    • Ende, N.1    Weinstein, F.2    Chen, R.3    Ende, M.4
  • 121
    • 10744223784 scopus 로고    scopus 로고
    • Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: Distribution, migration, and differentiation
    • Garbuzova-Davis S, Willing AE, Zigova T, et al. Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation. J Hematother Stem Cell Res 2003; 12: 255-70.
    • (2003) J Hematother Stem Cell Res , vol.12 , pp. 255-270
    • Garbuzova-Davis, S.1    Willing, A.E.2    Zigova, T.3
  • 122
    • 77955087538 scopus 로고    scopus 로고
    • The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease
    • Lee HJ, Lee JK, Lee H, et al. The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease. Neurosci Lett 2010; 481: 30-5.
    • (2010) Neurosci Lett , vol.481 , pp. 30-35
    • Lee, H.J.1    Lee, J.K.2    Lee, H.3
  • 123
    • 34547858511 scopus 로고    scopus 로고
    • Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons
    • Lee H, Shamy GA, Elkabetz Y, et al. Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons. Stem Cells 2007; 25: 1931-9.
    • (2007) Stem Cells , vol.25 , pp. 1931-1939
    • Lee, H.1    Shamy, G.A.2    Elkabetz, Y.3
  • 124
    • 0037047320 scopus 로고    scopus 로고
    • Directed differentiation of embryonic stem cells into motor neurons
    • Wichterle H, Lieberam I, Porter JA, Jessell TM. Directed differentiation of embryonic stem cells into motor neurons. Cell 2002; 110: 385-97.
    • (2002) Cell , vol.110 , pp. 385-397
    • Wichterle, H.1    Lieberam, I.2    Porter, J.A.3    Jessell, T.M.4
  • 125
    • 33750706917 scopus 로고    scopus 로고
    • Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
    • Roy NS, Cleren C, Singh SK, Yang L, Beal MF, Goldman SA. Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nat Med 2006; 12: 1259-68.
    • (2006) Nat Med , vol.12 , pp. 1259-1268
    • Roy, N.S.1    Cleren, C.2    Singh, S.K.3    Yang, L.4    Beal, M.F.5    Goldman, S.A.6
  • 126
    • 41849093685 scopus 로고    scopus 로고
    • Therapeutic cloning in individual parkinsonian mice
    • Tabar V, Tomishima M, Panagiotakos G, et al. Therapeutic cloning in individual parkinsonian mice. Nat Med 2008; 14: 379-81.
    • (2008) Nat Med , vol.14 , pp. 379-381
    • Tabar, V.1    Tomishima, M.2    Panagiotakos, G.3
  • 127
    • 65649115029 scopus 로고    scopus 로고
    • Directed differentiation of human-induced pluripotent stem cells generates active motor neurons
    • Karumbayaram S, Novitch BG, Patterson M, et al. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells 2009; 27: 806-11.
    • (2009) Stem Cells , vol.27 , pp. 806-811
    • Karumbayaram, S.1    Novitch, B.G.2    Patterson, M.3
  • 128
    • 79960055909 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: Opportunities and challenges
    • Okita K, Yamanaka S. Induced pluripotent stem cells: opportunities and challenges. Philos Trans R Soc Lond B Biol Sci 2011; 366: 2198-207.
    • (2011) Philos Trans R Soc Lond B Biol Sci , vol.366 , pp. 2198-2207
    • Okita, K.1    Yamanaka, S.2
  • 129
    • 22044452716 scopus 로고    scopus 로고
    • Infusion of human umbilical cord blood ameliorates neurologic deficits in rats with hemorrhagic brain injury
    • Nan Z, Grande A, Sanberg CD, Sanberg PR, Low WC. Infusion of human umbilical cord blood ameliorates neurologic deficits in rats with hemorrhagic brain injury. Ann N Y Acad Sci 2005; 1049: 84-96.
    • (2005) Ann N Y Acad Sci , vol.1049 , pp. 84-96
    • Nan, Z.1    Grande, A.2    Sanberg, C.D.3    Sanberg, P.R.4    Low, W.C.5
  • 130
    • 33745207410 scopus 로고    scopus 로고
    • Infusion of human umbilical cord blood cells protect against cerebral ischemia and damage during heatstroke in the rat
    • Chen SH, Chang FM, Tsai YC, Huang KF, Lin CL, Lin MT. Infusion of human umbilical cord blood cells protect against cerebral ischemia and damage during heatstroke in the rat. Exp Neurol 2006; 199: 67-76.
    • (2006) Exp Neurol , vol.199 , pp. 67-76
    • Chen, S.H.1    Chang, F.M.2    Tsai, Y.C.3    Huang, K.F.4    Lin, C.L.5    Lin, M.T.6
  • 131
    • 4143071470 scopus 로고    scopus 로고
    • Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex
    • Kelly S, Bliss TM, Shah AK, et al. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. Proc Natl Acad Sci USA 2004; 101: 11839-44.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11839-11844
    • Kelly, S.1    Bliss, T.M.2    Shah, A.K.3
  • 132
    • 58449092608 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells - characteristics and utility for drug discovery
    • Steel D, Hyllner J, Sartipy P. Cardiomyocytes derived from human embryonic stem cells - characteristics and utility for drug discovery. Curr Opin Drug Discov Devel 2009; 12: 133-40.
    • (2009) Curr Opin Drug Discov Devel , vol.12 , pp. 133-140
    • Steel, D.1    Hyllner, J.2    Sartipy, P.3
  • 133
    • 54349128090 scopus 로고    scopus 로고
    • Cardiomyocytes from embryonic stem cells: Towards human therapy
    • Foldes G, Harding SE, Ali NN. Cardiomyocytes from embryonic stem cells: towards human therapy. Expert Opin Biol Ther 2008; 8: 1473-83.
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 1473-1483
    • Foldes, G.1    Harding, S.E.2    Ali, N.N.3
  • 134
    • 0026343418 scopus 로고
    • Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers
    • Wobus AM, Wallukat G, Hescheler J. Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers. Differentiation 1991; 48: 173-82.
    • (1991) Differentiation , vol.48 , pp. 173-182
    • Wobus, A.M.1    Wallukat, G.2    Hescheler, J.3
  • 135
    • 0034904645 scopus 로고    scopus 로고
    • Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes
    • Kehat I, Kenyagin-Karsenti D, Snir M, et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest 2001; 108: 407-14.
    • (2001) J Clin Invest , vol.108 , pp. 407-414
    • Kehat, I.1    Kenyagin-Karsenti, D.2    Snir, M.3
  • 136
    • 0038300672 scopus 로고    scopus 로고
    • Human embryonic stem cells develop into multiple types of cardiac myocytes: Action potential characterization
    • He JQ, Ma Y, Lee Y, Thomson JA, Kamp TJ. Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization. Circ Res 2003; 93: 32-9.
    • (2003) Circ Res , vol.93 , pp. 32-39
    • He, J.Q.1    Ma, Y.2    Lee, Y.3    Thomson, J.A.4    Kamp, T.J.5
  • 137
    • 0037312345 scopus 로고    scopus 로고
    • Differentiation and genetic manipulation of human embryonic stem cells and the analysis of the cardiovascular system
    • Lavon N, Benvenisty N. Differentiation and genetic manipulation of human embryonic stem cells and the analysis of the cardiovascular system. Trends Cardiovasc Med 2003; 13: 47-52.
    • (2003) Trends Cardiovasc Med , vol.13 , pp. 47-52
    • Lavon, N.1    Benvenisty, N.2
  • 138
    • 0038210217 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes: Role of coculture with visceral endoderm-like cells
    • Mummery C, Ward-van Oostwaard D, Doevendans P, et al. Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation 2003; 107: 2733-40.
    • (2003) Circulation , vol.107 , pp. 2733-2740
    • Mummery, C.1    Ward-van Oostwaard, D.2    Doevendans, P.3
  • 139
    • 77952306707 scopus 로고    scopus 로고
    • Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors
    • Moretti A, Bellin M, Jung CB, et al. Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. Faseb J 2010; 24: 700-11.
    • (2010) Faseb J , vol.24 , pp. 700-711
    • Moretti, A.1    Bellin, M.2    Jung, C.B.3
  • 140
    • 8744262864 scopus 로고    scopus 로고
    • Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ stem cells, and mononu clear cells expressing early cardiac, muscle, and endothelial markers into peripheral blood in patients with acute myocardial infarction
    • Wojakowski W, Tendera M, Michalowska A, et al. Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ stem cells, and mononu clear cells expressing early cardiac, muscle, and endothelial markers into peripheral blood in patients with acute myocardial infarction. Circulation 2004; 110: 3213-20.
    • (2004) Circulation , vol.110 , pp. 3213-3220
    • Wojakowski, W.1    Tendera, M.2    Michalowska, A.3
  • 141
    • 42749084311 scopus 로고    scopus 로고
    • Bone marrow-derived pluripotent very small embryonic-like stem cells (VSELs) are mobilized after acute myocardial infarction
    • Zuba-Surma EK, Kucia M, Dawn B, Guo Y, Ratajczak MZ, Bolli R. Bone marrow-derived pluripotent very small embryonic-like stem cells (VSELs) are mobilized after acute myocardial infarction. J Mol Cell Cardiol 2008; 44: 865-73.
    • (2008) J Mol Cell Cardiol , vol.44 , pp. 865-873
    • Zuba-Surma, E.K.1    Kucia, M.2    Dawn, B.3    Guo, Y.4    Ratajczak, M.Z.5    Bolli, R.6
  • 142
    • 0742324499 scopus 로고    scopus 로고
    • Tissue-specific muscle, neural and liver stem/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury
    • Kucia M, Ratajczak J, Reca R, Janowska-Wieczorek A, Ratajczak MZ. Tissue-specific muscle, neural and liver stem/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury. Blood Cells Mol Dis 2004; 32: 52-7.
    • (2004) Blood Cells Mol Dis , vol.32 , pp. 52-57
    • Kucia, M.1    Ratajczak, J.2    Reca, R.3    Janowska-Wieczorek, A.4    Ratajczak, M.Z.5
  • 143
    • 78549242967 scopus 로고    scopus 로고
    • Evidence of Mobilization of Pluripotent Stem Cells into Peripheral Blood of Patients with Myocardial Ischemia
    • Abdel-Latif A, Zuba-Surma EK, Ziada KM, et al. Evidence of Mobilization of Pluripotent Stem Cells into Peripheral Blood of Patients with Myocardial Ischemia. Exp Hematol 2010.
    • (2010) Exp Hematol
    • Abdel-Latif, A.1    Zuba-Surma, E.K.2    Ziada, K.M.3
  • 144
    • 77954152205 scopus 로고    scopus 로고
    • Cardiomyocyte differentiation of bone marrow-derived Oct-4+CXCR4+SSEA-1+ very small embryonic-like stem cells
    • Wojakowski W, Tendera M, Kucia M, et al. Cardiomyocyte differentiation of bone marrow-derived Oct-4+CXCR4+SSEA-1+ very small embryonic-like stem cells. Int J Oncol 2010; 37: 237-47.
    • (2010) Int J Oncol , vol.37 , pp. 237-247
    • Wojakowski, W.1    Tendera, M.2    Kucia, M.3
  • 145
    • 49649095887 scopus 로고    scopus 로고
    • Neuroscience: Standard model
    • Schnabel J. Neuroscience: Standard model. Nature 2008; 454: 682-5.
    • (2008) Nature , vol.454 , pp. 682-685
    • Schnabel, J.1
  • 146
    • 67650891858 scopus 로고    scopus 로고
    • Human neurospheres as three-dimensional cellular systems for developmental neurotoxicity testing
    • Moors M, Rockel TD, Abel J, et al. Human neurospheres as three-dimensional cellular systems for developmental neurotoxicity testing. Environ Health Perspect 2009; 117: 1131-8.
    • (2009) Environ Health Perspect , vol.117 , pp. 1131-1138
    • Moors, M.1    Rockel, T.D.2    Abel, J.3
  • 147
    • 77958616943 scopus 로고    scopus 로고
    • A stem cell-based tool for small molecule screening in adipogenesis
    • Qin J, Li WQ, Zhang L, et al. A stem cell-based tool for small molecule screening in adipogenesis. PLoS One 2010; 5: e13014.
    • (2010) PLoS One , vol.5
    • Qin, J.1    Li, W.Q.2    Zhang, L.3
  • 148
    • 78650469789 scopus 로고    scopus 로고
    • Applications of patient-specific induced pluripotent stem cells; focused on disease modeling, drug screening and therapeutic potentials for liver disease
    • Chun YS, Chaudhari P, Jang YY. Applications of patient-specific induced pluripotent stem cells; focused on disease modeling, drug screening and therapeutic potentials for liver disease. Int J Biol Sci 2010; 6: 796-805.
    • (2010) Int J Biol Sci , vol.6 , pp. 796-805
    • Chun, Y.S.1    Chaudhari, P.2    Jang, Y.Y.3
  • 149
    • 58249110796 scopus 로고    scopus 로고
    • Induced pluripotent stem cells from a spinal muscular atrophy patient
    • Ebert AD, Yu J, Rose FF, Jr., et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009; 457: 277-80.
    • (2009) Nature , vol.457 , pp. 277-280
    • Ebert, A.D.1    Yu, J.2    Rose Jr., F.F.3
  • 150
    • 0033987669 scopus 로고    scopus 로고
    • A mouse model for spinal muscular atrophy
    • Hsieh-Li HM, Chang JG, Jong YJ, et al. A mouse model for spinal muscular atrophy. Nat Genet 2000; 24: 66-70.
    • (2000) Nat Genet , vol.24 , pp. 66-70
    • Hsieh-Li, H.M.1    Chang, J.G.2    Jong, Y.J.3
  • 151
    • 0034639645 scopus 로고    scopus 로고
    • The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy
    • Monani UR, Sendtner M, Coovert DD, et al. The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy. Hum Mol Genet 2000; 9: 333-9.
    • (2000) Hum Mol Genet , vol.9 , pp. 333-339
    • Monani, U.R.1    Sendtner, M.2    Coovert, D.D.3
  • 153
    • 70349301819 scopus 로고    scopus 로고
    • Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
    • Lee G, Papapetrou EP, Kim H, et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 2009; 461: 402-6.
    • (2009) Nature , vol.461 , pp. 402-406
    • Lee, G.1    Papapetrou, E.P.2    Kim, H.3
  • 155
    • 34547454243 scopus 로고    scopus 로고
    • A humanized IKBKAP transgenic mouse models a tissue-specific human splicing defect
    • Hims MM, Shetty RS, Pickel J, et al. A humanized IKBKAP transgenic mouse models a tissue-specific human splicing defect. Genomics 2007; 90: 389-96.
    • (2007) Genomics , vol.90 , pp. 389-396
    • Hims, M.M.1    Shetty, R.S.2    Pickel, J.3
  • 156
    • 79952446402 scopus 로고    scopus 로고
    • Modelling the long QT syndrome with induced pluripotent stem cells
    • Itzhaki I, Maizels L, Huber I, et al. Modelling the long QT syndrome with induced pluripotent stem cells. Nature 2011; 471: 225-9.
    • (2011) Nature , vol.471 , pp. 225-229
    • Itzhaki, I.1    Maizels, L.2    Huber, I.3
  • 158
    • 0037049999 scopus 로고    scopus 로고
    • Cardiac channelopathies
    • Marban E. Cardiac channelopathies. Nature 2002; 415: 213-8.
    • (2002) Nature , vol.415 , pp. 213-218
    • Marban, E.1
  • 160
    • 9044240040 scopus 로고    scopus 로고
    • Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias
    • Wang Q, Curran ME, Splawski I, et al. Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias. Nat Genet 1996; 12: 17-23.
    • (1996) Nat Genet , vol.12 , pp. 17-23
    • Wang, Q.1    Curran, M.E.2    Splawski, I.3
  • 161
    • 0028905566 scopus 로고
    • SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome
    • Wang Q, Shen J, Splawski I, et al. SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome. Cell 1995; 80: 805-11.
    • (1995) Cell , vol.80 , pp. 805-811
    • Wang, Q.1    Shen, J.2    Splawski, I.3
  • 162
    • 74949133926 scopus 로고    scopus 로고
    • Progress toward the clinical application of patient-specific pluripotent stem cells
    • Kiskinis E, Eggan K. Progress toward the clinical application of patient-specific pluripotent stem cells. J Clin Invest 2010; 120: 51-9.
    • (2010) J Clin Invest , vol.120 , pp. 51-59
    • Kiskinis, E.1    Eggan, K.2
  • 166
    • 4644341747 scopus 로고    scopus 로고
    • Human hepatocytes in primary culture: The choice to investigate drug metabolism in man
    • Gomez-Lechon MJ, Donato MT, Castell JV, Jover R. Human hepatocytes in primary culture: the choice to investigate drug metabolism in man. Curr Drug Metab 2004; 5: 443-62.
    • (2004) Curr Drug Metab , vol.5 , pp. 443-462
    • Gomez-Lechon, M.J.1    Donato, M.T.2    Castell, J.V.3    Jover, R.4
  • 167
    • 36148955117 scopus 로고    scopus 로고
    • Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells
    • Westerink WM, Schoonen WG. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells. Toxicol In vitro 2007; 21: 1581-91.
    • (2007) Toxicol In Vitro , vol.21 , pp. 1581-1591
    • Westerink, W.M.1    Schoonen, W.G.2
  • 168
    • 0036301269 scopus 로고    scopus 로고
    • Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: Molecular mechanisms that determine lower expression in cultured cells
    • Rodriguez-Antona C, Donato MT, Boobis A, et al. Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells. Xenobiotica 2002; 32: 505-20.
    • (2002) Xenobiotica , vol.32 , pp. 505-520
    • Rodriguez-Antona, C.1    Donato, M.T.2    Boobis, A.3
  • 169
    • 34547620338 scopus 로고    scopus 로고
    • Embryonic stem cells as a source of models for drug discovery
    • Pouton CW, Haynes JM. Embryonic stem cells as a source of models for drug discovery. Nat Rev Drug Discov 2007; 6: 605-16.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 605-616
    • Pouton, C.W.1    Haynes, J.M.2
  • 170
    • 34247107563 scopus 로고    scopus 로고
    • Bioprocessing of embryonic stem cells for drug discovery
    • Thomson H. Bioprocessing of embryonic stem cells for drug discovery. Trends Biotechnol 2007; 25: 224-30.
    • (2007) Trends Biotechnol , vol.25 , pp. 224-230
    • Thomson, H.1
  • 172
    • 0035934070 scopus 로고    scopus 로고
    • Risk of cardiovascular events associated with selective COX-2 inhibitors
    • Mukherjee D, Nissen SE, Topol EJ. Risk of cardiovascular events associated with selective COX-2 inhibitors. Jama 2001; 286: 954-9.
    • (2001) Jama , vol.286 , pp. 954-959
    • Mukherjee, D.1    Nissen, S.E.2    Topol, E.J.3
  • 173
    • 66949171305 scopus 로고    scopus 로고
    • Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron
    • Simunek T, Sterba M, Popelova O, Adamcova M, Hrdina R, Gersl V. Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron. Pharmacol Rep 2009; 61: 154-71.
    • (2009) Pharmacol Rep , vol.61 , pp. 154-171
    • Simunek, T.1    Sterba, M.2    Popelova, O.3    Adamcova, M.4    Hrdina, R.5    Gersl, V.6
  • 174
    • 0015849162 scopus 로고
    • A clinicopathologic analysis of adriamycin cardiotoxicity
    • Lefrak EA, Pitha J, Rosenheim S, Gottlieb JA. A clinicopathologic analysis of adriamycin cardiotoxicity. Cancer 1973; 32: 302-14.
    • (1973) Cancer , vol.32 , pp. 302-314
    • Lefrak, E.A.1    Pitha, J.2    Rosenheim, S.3    Gottlieb, J.A.4
  • 175
    • 33845435347 scopus 로고    scopus 로고
    • Drug-induced long QT and torsade de pointes: Recent advances
    • Kannankeril PJ, Roden DM. Drug-induced long QT and torsade de pointes: recent advances. Curr Opin Cardiol 2007; 22: 39-43.
    • (2007) Curr Opin Cardiol , vol.22 , pp. 39-43
    • Kannankeril, P.J.1    Roden, D.M.2
  • 176
    • 77950481059 scopus 로고    scopus 로고
    • Stabilization of mitochondrial membrane potential prevents doxorubicin-induced cardiotoxicity in isolated rat heart
    • Montaigne D, Marechal X, Baccouch R, et al. Stabilization of mitochondrial membrane potential prevents doxorubicin-induced cardiotoxicity in isolated rat heart. Toxicol Appl Pharmacol 2010.
    • (2010) Toxicol Appl Pharmacol
    • Montaigne, D.1    Marechal, X.2    Baccouch, R.3
  • 177
    • 33646819975 scopus 로고    scopus 로고
    • Thrombopoietin protects against in vitro and in vivo cardiotoxicity induced by doxorubicin
    • Li K, Sung RY, Huang WZ, et al. Thrombopoietin protects against in vitro and in vivo cardiotoxicity induced by doxorubicin. Circulation 2006; 113: 2211-20.
    • (2006) Circulation , vol.113 , pp. 2211-2220
    • Li, K.1    Sung, R.Y.2    Huang, W.Z.3
  • 178
    • 56349109414 scopus 로고    scopus 로고
    • Long-term primary cultures of human adult atrial cardiac myocytes: Cell viability, structural properties and BNP secretion in vitro
    • Bistola V, Nikolopoulou M, Derventzi A, et al. Long-term primary cultures of human adult atrial cardiac myocytes: cell viability, structural properties and BNP secretion in vitro. Int J Cardiol 2008; 131: 113-22.
    • (2008) Int J Cardiol , vol.131 , pp. 113-122
    • Bistola, V.1    Nikolopoulou, M.2    Derventzi, A.3
  • 179
    • 66349105917 scopus 로고    scopus 로고
    • Metformin prevents progression of heart failure in dogs: Role of AMP-activated protein kinase
    • Sasaki H, Asanuma H, Fujita M, et al. Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase. Circulation 2009; 119: 2568-77.
    • (2009) Circulation , vol.119 , pp. 2568-2577
    • Sasaki, H.1    Asanuma, H.2    Fujita, M.3
  • 180
    • 0029063772 scopus 로고
    • Sympathetic activation, ventricular repolarization and Ikr blockade: Implications for the antifibrillatory efficacy of potassium channel blocking agents
    • Vanoli E, Priori SG, Nakagawa H, et al. Sympathetic activation, ventricular repolarization and Ikr blockade: implications for the antifibrillatory efficacy of potassium channel blocking agents. J Am Coll Cardiol 1995; 25: 1609-14.
    • (1995) J Am Coll Cardiol , vol.25 , pp. 1609-1614
    • Vanoli, E.1    Priori, S.G.2    Nakagawa, H.3
  • 182
    • 70349385430 scopus 로고    scopus 로고
    • Embryonic stem cellderived cardiomyocytes as a model system to study cardioprotective effects of dexamethasone in doxorubicin cardiotoxicity
    • Farokhpour M, Karbalaie K, Tanhaei S, et al. Embryonic stem cellderived cardiomyocytes as a model system to study cardioprotective effects of dexamethasone in doxorubicin cardiotoxicity. Toxicol In vitro 2009; 23: 1422-8.
    • (2009) Toxicol In Vitro , vol.23 , pp. 1422-1428
    • Farokhpour, M.1    Karbalaie, K.2    Tanhaei, S.3
  • 183
    • 67349123365 scopus 로고    scopus 로고
    • In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
    • Tanaka T, Tohyama S, Murata M, et al. In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochem Biophys Res Commun 2009; 385: 497-502.
    • (2009) Biochem Biophys Res Commun , vol.385 , pp. 497-502
    • Tanaka, T.1    Tohyama, S.2    Murata, M.3
  • 187
    • 37549004394 scopus 로고    scopus 로고
    • The influence of CYP3A5 expression on the extent of hepatic CYP3A inhibition is substrate-dependent: An in vitro-in vivo evaluation
    • Isoherranen N, Ludington SR, Givens RC, et al. The influence of CYP3A5 expression on the extent of hepatic CYP3A inhibition is substrate-dependent: an in vitro-in vivo evaluation. Drug Metab Dispos 2008; 36: 146-54.
    • (2008) Drug Metab Dispos , vol.36 , pp. 146-154
    • Isoherranen, N.1    Ludington, S.R.2    Givens, R.C.3
  • 190
    • 34248634898 scopus 로고    scopus 로고
    • Directed differentiation of human embryonic stem cells into functional hepatic cells
    • Cai J, Zhao Y, Liu Y, et al. Directed differentiation of human embryonic stem cells into functional hepatic cells. Hepatology 2007; 45: 1229-39.
    • (2007) Hepatology , vol.45 , pp. 1229-1239
    • Cai, J.1    Zhao, Y.2    Liu, Y.3
  • 191
    • 37349037630 scopus 로고    scopus 로고
    • Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells in vitro and in vivo
    • Duan Y, Catana A, Meng Y, et al. Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells in vitro and in vivo. Stem Cells 2007; 25: 3058-68.
    • (2007) Stem Cells , vol.25 , pp. 3058-3068
    • Duan, Y.1    Catana, A.2    Meng, Y.3
  • 192
    • 47949092668 scopus 로고    scopus 로고
    • Efficient differentiation of functional hepatocytes from human embryonic stem cells
    • Agarwal S, Holton KL, Lanza R. Efficient differentiation of functional hepatocytes from human embryonic stem cells. Stem Cells 2008; 26: 1117-27.
    • (2008) Stem Cells , vol.26 , pp. 1117-1127
    • Agarwal, S.1    Holton, K.L.2    Lanza, R.3
  • 193
    • 79958019157 scopus 로고    scopus 로고
    • Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project
    • Mandenius CF, Andersson TB, Alves PM, et al. Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project. Altern Lab Anim 2011; 39: 147-71.
    • (2011) Altern Lab Anim , vol.39 , pp. 147-171
    • Mandenius, C.F.1    Andersson, T.B.2    Alves, P.M.3
  • 194
    • 70449534874 scopus 로고    scopus 로고
    • Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells
    • Song Z, Cai J, Liu Y, et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res 2009; 19: 1233-42.
    • (2009) Cell Res , vol.19 , pp. 1233-1242
    • Song, Z.1    Cai, J.2    Liu, Y.3
  • 195
    • 79551631405 scopus 로고    scopus 로고
    • Efficient generation of hepatoblasts from human ES cells and iPS cells by transient overexpression of homeobox gene HEX
    • Inamura M, Kawabata K, Takayama K, et al. Efficient generation of hepatoblasts from human ES cells and iPS cells by transient overexpression of homeobox gene HEX. Mol Ther 2011; 19: 400-7.
    • (2011) Mol Ther , vol.19 , pp. 400-407
    • Inamura, M.1    Kawabata, K.2    Takayama, K.3
  • 196
    • 77956354416 scopus 로고    scopus 로고
    • Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells
    • Rashid ST, Corbineau S, Hannan N, et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. J Clin Invest 2010; 120: 3127-36.
    • (2010) J Clin Invest , vol.120 , pp. 3127-3136
    • Rashid, S.T.1    Corbineau, S.2    Hannan, N.3
  • 198
    • 0033106384 scopus 로고    scopus 로고
    • Cardiomyocytes can be generated from marrow stromal cells in vitro
    • Makino S, Fukuda K, Miyoshi S, et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest 1999; 103: 697-705.
    • (1999) J Clin Invest , vol.103 , pp. 697-705
    • Makino, S.1    Fukuda, K.2    Miyoshi, S.3
  • 199
    • 0037079996 scopus 로고    scopus 로고
    • Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents
    • Gritti A, Bonfanti L, Doetsch F, et al. Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents. J Neurosci 2002; 22: 437-45.
    • (2002) J Neurosci , vol.22 , pp. 437-445
    • Gritti, A.1    Bonfanti, L.2    Doetsch, F.3
  • 200
    • 0027436182 scopus 로고
    • Hepatic progenitor populations in embryonic, neonatal, and adult liver
    • Brill S, Holst P, Sigal S, et al. Hepatic progenitor populations in embryonic, neonatal, and adult liver. Proc Soc Exp Biol Med 1993; 204: 261-9.
    • (1993) Proc Soc Exp Biol Med , vol.204 , pp. 261-269
    • Brill, S.1    Holst, P.2    Sigal, S.3
  • 201
    • 20544441737 scopus 로고    scopus 로고
    • A Pax3/Pax7-dependent population of skeletal muscle progenitor cells
    • Relaix F, Rocancourt D, Mansouri A, Buckingham M. A Pax3/Pax7-dependent population of skeletal muscle progenitor cells. Nature 2005; 435: 948-53.
    • (2005) Nature , vol.435 , pp. 948-953
    • Relaix, F.1    Rocancourt, D.2    Mansouri, A.3    Buckingham, M.4
  • 203
    • 7244261795 scopus 로고    scopus 로고
    • Isolation and expansion of adult cardiac stem cells from human and murine heart
    • Messina E, De Angelis L, Frati G, et al. Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res 2004; 95: 911-21.
    • (2004) Circ Res , vol.95 , pp. 911-921
    • Messina, E.1    de Angelis, L.2    Frati, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.