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Volumn 6, Issue 7, 2010, Pages 796-805

Applications of patient-specific induced pluripotent stem cells; focused on disease modeling, drug screening and therapeutic potentials for liver disease

Author keywords

Disease modeling; Drug screening; Liver disease; Stem cell

Indexed keywords


EID: 78650469789     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.6.796     Document Type: Review
Times cited : (86)

References (75)
  • 1
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126:663-76
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 2
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861-72
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 3
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga Otte-K et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318:1917-20
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga, O.-K.3
  • 4
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • Park IH, Zhao R, West JA et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008; 451:141-6
    • (2008) Nature , vol.451 , pp. 141-146
    • Park, I.H.1    Zhao, R.2    West, J.A.3
  • 5
    • 50549089957 scopus 로고    scopus 로고
    • Disease-specific induced pluripotent stem cells
    • Park IH, Arora N, Huo H et al. Disease-specific induced pluripotent stem cells. Cell 2008; 134:877-86
    • (2008) Cell , vol.134 , pp. 877-886
    • Park, I.H.1    Arora, N.2    Huo, H.3
  • 6
    • 50149098605 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    • Dimos JT, Rodolfa KT, Niakan KK et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 2008; 321:1218-21
    • (2008) Science , vol.321 , pp. 1218-1221
    • Dimos, J.T.1    Rodolfa, K.T.2    Niakan, K.K.3
  • 8
    • 67650095306 scopus 로고    scopus 로고
    • Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
    • Raya A, Rodriguez-Piza I, Guenechea G et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 2009; 460:53-9
    • (2009) Nature , vol.460 , pp. 53-59
    • Raya, A.1    Rodriguez-Piza, I.2    Guenechea, G.3
  • 9
    • 78049512763 scopus 로고    scopus 로고
    • Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA·TTC triplet repeat instability
    • Ku S, Soraguni E, Campau E et al. Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA·TTC triplet repeat instability. Cell Stem Cell 2010; 7:631-7
    • (2010) Cell Stem Cell , vol.7 , pp. 631-637
    • Ku, S.1    Soraguni, E.2    Campau, E.3
  • 10
    • 70349301819 scopus 로고    scopus 로고
    • Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
    • Lee G, Papapetrou EP, Kim H et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 2009; 461:402-6
    • (2009) Nature , vol.461 , pp. 402-406
    • Lee, G.1    Papapetrou, E.P.2    Kim, H.3
  • 11
    • 58249110796 scopus 로고    scopus 로고
    • Induced pluripotent stem cells from a spinal muscular atrophy patient
    • Ebert AD, Yu J, Rose FF Jr et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009; 457:277-80
    • (2009) Nature , vol.457 , pp. 277-280
    • Ebert, A.D.1    Yu, J.2    Rose Jr., F.F.3
  • 12
    • 61349100729 scopus 로고    scopus 로고
    • Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
    • Soldner F, Hockemeyer D, Beard C et al. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 2009; 136:964-77
    • (2009) Cell , vol.136 , pp. 964-977
    • Soldner, F.1    Hockemeyer, D.2    Beard, C.3
  • 13
    • 67649880603 scopus 로고    scopus 로고
    • Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic disease
    • Ye L, Chang JC, Lin C et al. Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic disease. Proc Natl Acad Sci USA 2009; 106:9826-30
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9826-9830
    • Ye, L.1    Chang, J.C.2    Lin, C.3
  • 14
    • 77953443251 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
    • Carvajal-Vergara X, Sevilla A, D'Souza SL et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 2010; 465:808-12
    • (2010) Nature , vol.465 , pp. 808-812
    • Carvajal-Vergara, X.1    Sevilla, A.2    D'Souza, S.L.3
  • 15
    • 77956354416 scopus 로고    scopus 로고
    • Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells
    • Rashid ST, Corbineau S, Hanna N et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. J Clin Invest 2010; 120:3127-36
    • (2010) J Clin Invest , vol.120 , pp. 3127-3136
    • Rashid, S.T.1    Corbineau, S.2    Hanna, N.3
  • 16
    • 77957347780 scopus 로고    scopus 로고
    • Generation of liver disease-specific induced pluripotent stem cells along with efficient differentiation to functional hepatocyte-like cells
    • Ghodsizadeh A, Taei A, Totonchi M et al. Generation of liver disease-specific induced pluripotent stem cells along with efficient differentiation to functional hepatocyte-like cells. Stem Cell Rev and Rep 2010; 6:622-32
    • (2010) Stem Cell Rev and Rep , vol.6 , pp. 622-632
    • Ghodsizadeh, A.1    Taei, A.2    Totonchi, M.3
  • 17
    • 78149488365 scopus 로고    scopus 로고
    • A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells
    • Marchetto MC, Carromeu C, Acab A et al. A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells. Cell 2010; 143:527-39
    • (2010) Cell , vol.143 , pp. 527-539
    • Marchetto, M.C.1    Carromeu, C.2    Acab, A.3
  • 18
    • 84873337576 scopus 로고    scopus 로고
    • Characterization of human Huntington's disease cell model from induced pluripotent stem cells
    • Zhang N, An MC, Montoro D et al. Characterization of human Huntington's disease cell model from induced pluripotent stem cells. PLos Curr 2010; 2:RRN1193
    • (2010) PLos Curr , vol.2
    • Zhang, N.1    An, M.C.2    Montoro, D.3
  • 19
    • 70449534874 scopus 로고    scopus 로고
    • Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells
    • Song Z, Cai J, Liu Y et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res 2009; 19:1233-42
    • (2009) Cell Res , vol.19 , pp. 1233-1242
    • Song, Z.1    Cai, J.2    Liu, Y.3
  • 20
    • 47949092668 scopus 로고    scopus 로고
    • Efficient differentiation of functional hepatocytes from human embryonic stem cells
    • Agarwal S, Holton KL, Lanza R. Efficient differentiation of functional hepatocytes from human embryonic stem cells. Stem Cells 2008; 26:1117-27
    • (2008) Stem Cells , vol.26 , pp. 1117-1127
    • Agarwal, S.1    Holton, K.L.2    Lanza, R.3
  • 21
    • 73449100456 scopus 로고    scopus 로고
    • Generation of functional human hepatic endoderm from human induced pluripotent stem cells
    • Sullivan GJ, Hay DC, Park IH et al. Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology 2010; 51:329-35
    • (2010) Hepatology , vol.51 , pp. 329-335
    • Sullivan, G.J.1    Hay, D.C.2    Park, I.H.3
  • 22
    • 77951473757 scopus 로고    scopus 로고
    • Generation of endoderm-derived human induced pluripotent stem cells from primary hepatocytes
    • Liu H, Ye Z, Kim Y et al. Generation of endoderm-derived human induced pluripotent stem cells from primary hepatocytes. Hepatology 2010; 51:1810-19
    • (2010) Hepatology , vol.51 , pp. 1810-1819
    • Liu, H.1    Ye, Z.2    Kim, Y.3
  • 25
    • 33751516578 scopus 로고    scopus 로고
    • Isolation and characterization of a stem cell population from adult human liver
    • Herrera MB, Bruno S, Buttiglieri S et al. Isolation and characterization of a stem cell population from adult human liver. Stem Cells 2006; 24:2840-50
    • (2006) Stem Cells , vol.24 , pp. 2840-2850
    • Herrera, M.B.1    Bruno, S.2    Buttiglieri, S.3
  • 26
    • 0032404146 scopus 로고    scopus 로고
    • Generati on of hepatocytes from oval cell precursors in culture
    • Lazaro CA, Rhim JA, Yamada Y et al. Generati on of hepatocytes from oval cell precursors in culture. Cancer Res 1998; 58:5514-22
    • (1998) Cancer Res , vol.58 , pp. 5514-5522
    • Lazaro, C.A.1    Rhim, J.A.2    Yamada, Y.3
  • 27
    • 41149135381 scopus 로고    scopus 로고
    • Isolation and characterization of a novel population of progenitor cells from unmanipulated rat liver
    • Sahin MB, Schwartz RE, Buckley SM et al. Isolation and characterization of a novel population of progenitor cells from unmanipulated rat liver. Liver Transpl 2008; 14:333-45
    • (2008) Liver Transpl , vol.14 , pp. 333-345
    • Sahin, M.B.1    Schwartz, R.E.2    Buckley, S.M.3
  • 28
    • 0345547430 scopus 로고    scopus 로고
    • Potential of embryonic and adult stem cells in vitro
    • Czyz J, Wiese C, Rolletschek A et al. Potential of embryonic and adult stem cells in vitro. Biol Chem 2003; 384:1391-409
    • (2003) Biol Chem , vol.384 , pp. 1391-1409
    • Czyz, J.1    Wiese, C.2    Rolletschek, A.3
  • 29
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline- competent induced pluripotent stem cells
    • Okita K, Ichisaka T, Yamanaka S. Generation of germline- competent induced pluripotent stem cells. Nature 2007; 448:318-24
    • (2007) Nature , vol.448 , pp. 318-324
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 30
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • Nakagawa M, Koyanagi M, Tanabe K et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008; 26:101-6
    • (2008) Nat Biotechnol , vol.26 , pp. 101-106
    • Nakagawa, M.1    Koyanagi, M.2    Tanabe, K.3
  • 31
    • 64749111225 scopus 로고    scopus 로고
    • Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    • Kaji K, Norrby K, Paca A et al. Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 2009; 458:771-5
    • (2009) Nature , vol.458 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3
  • 32
    • 64749083939 scopus 로고    scopus 로고
    • Piggyback transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen K, Michael IP, Mohseni P et al. piggyback transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 2009; 458:766-70
    • (2009) Nature , vol.458 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3
  • 33
    • 55849115999 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • Stadtfeld M, Nagaya M, Utikal J et al. Induced pluripotent stem cells generated without viral integration. Science 2008; 322:945-9
    • (2008) Science , vol.322 , pp. 945-949
    • Stadtfeld, M.1    Nagaya, M.2    Utikal, J.3
  • 34
    • 70450265981 scopus 로고    scopus 로고
    • Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
    • Fusaki N, Ban H, Nishiyama A et al. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci 2009; 85:348-62
    • (2009) Proc Jpn Acad Ser B Phys Biol Sci , vol.85 , pp. 348-362
    • Fusaki, N.1    Ban, H.2    Nishiyama, A.3
  • 35
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • Okita K, Nakagawa M, Hyenjong H et al. Generation of mouse induced pluripotent stem cells without viral vectors. Science 2008; 322:949-53
    • (2008) Science , vol.322 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3
  • 36
    • 65649116572 scopus 로고    scopus 로고
    • Human induced pluripotent stem cells free of vector and transgene sequences
    • Yu J, Hu K, Smuga-Otto K et al. Human induced pluripotent stem cells free of vector and transgene sequences. Science 2009; 324:797-801
    • (2009) Science , vol.324 , pp. 797-801
    • Yu, J.1    Hu, K.2    Smuga-Otto, K.3
  • 37
    • 46949085597 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
    • Huangfu D, Maehr R, Guo W et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 2008; 26:795-7
    • (2008) Nat Biotechnol , vol.26 , pp. 795-797
    • Huangfu, D.1    Maehr, R.2    Guo, W.3
  • 38
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • Zhou H, Wu S, Joo JY et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009; 4:381-4
    • (2009) Cell Stem Cell , vol.4 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3
  • 39
    • 77958536106 scopus 로고    scopus 로고
    • Highly efficient reprogramming to pluripotency and directed differentiation of human cell with synthetic modified mRNA
    • Warren L, Manos PD, Ahfeldt T et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cell with synthetic modified mRNA. Cell Stem Cell 2010; 7:618-30
    • (2010) Cell Stem Cell , vol.7 , pp. 618-630
    • Warren, L.1    Manos, P.D.2    Ahfeldt, T.3
  • 40
    • 68249087053 scopus 로고    scopus 로고
    • Variation in the safety of induced pluripotent stem cell lines
    • Miura K, Okada Y, Aoi T et al. Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol 2009; 27:743-45
    • (2009) Nat Biotechnol , vol.27 , pp. 743-745
    • Miura, K.1    Okada, Y.2    Aoi, T.3
  • 41
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • Kim K, Doi A, Wen B et al. Epigenetic memory in induced pluripotent stem cells. Nature 2010; 467:280-1
    • (2010) Nature , vol.467 , pp. 280-281
    • Kim, K.1    Doi, A.2    Wen, B.3
  • 42
    • 78650752402 scopus 로고    scopus 로고
    • Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
    • Polo JM, Liu S, Figueroa ME et al. Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nature Biotechnol 2010; 28:848-55
    • (2010) Nature Biotechnol , vol.28 , pp. 848-855
    • Polo, J.M.1    Liu, S.2    Figueroa, M.E.3
  • 43
    • 70349445082 scopus 로고    scopus 로고
    • Transcriptional signature and memory retention of human induced pluripotent stem cells
    • Marchetto MCN, Yeo GW, Kainohana O et al. Transcriptional signature and memory retention of human induced pluripotent stem cells. PLoS One 2009; 4:e7076
    • (2009) PLoS One , vol.4
    • Marchetto, M.C.N.1    Yeo, G.W.2    Kainohana, O.3
  • 44
    • 33745532794 scopus 로고    scopus 로고
    • Genetics of hepatocelluar tumors
    • Laurent-Puig P, Zucman-Rossi J. Genetics of hepatocelluar tumors. Oncogenes 2006; 25:3778-86
    • (2006) Oncogenes , vol.25 , pp. 3778-3786
    • Laurent-Puig, P.1    Zucman-Rossi, J.2
  • 45
    • 18644363653 scopus 로고    scopus 로고
    • Bi-allelic inactivation of TCF1 in hepatic adenomas
    • Bluteau O, Jeannot E, Bioulac Sage P et al. Bi-allelic inactivation of TCF1 in hepatic adenomas. Nat Genet 2002; 32:312-5
    • (2002) Nat Genet , vol.32 , pp. 312-315
    • Bluteau, O.1    Jeannot, E.2    Bioulac Sage, P.3
  • 46
    • 0035395236 scopus 로고    scopus 로고
    • Beta-catenin mutation and overexpression in hepatocellular carcinoma: Clinicopathologic and prognostic significance
    • Wong CM, Fan ST, Ng IO. Beta-catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance. Cancer 2001; 92:136-45
    • (2001) Cancer , vol.92 , pp. 136-145
    • Wong, C.M.1    Fan, S.T.2    Ng, I.O.3
  • 47
    • 0027241524 scopus 로고
    • Tumor progression in hepatocellular carcinoma may be mediated by p53 mutation
    • Tanaka S, Toh Y, Adachi E et al. Tumor progression in hepatocellular carcinoma may be mediated by p53 mutation. Cancer Res 1993; 53:2884-7
    • (1993) Cancer Res , vol.53 , pp. 2884-2887
    • Tanaka, S.1    Toh, Y.2    Adachi, E.3
  • 48
    • 78650429291 scopus 로고    scopus 로고
    • Multistage hepatic differentiation from human induced pluripotent stem cells
    • in press
    • Choi SM, Liu H, Kim Y et al. Multistage hepatic differentiation from human induced pluripotent stem cells. Methods and Protocols 2010, in press
    • (2010) Methods and Protocols
    • Choi, S.M.1    Liu, H.2    Kim, Y.3
  • 49
    • 77953250105 scopus 로고    scopus 로고
    • Generation of iPSCs from cultured human malignant cells
    • Carette JE, Pruszak J, Varadarjan M et al. Generation of iPSCs from cultured human malignant cells. Blood 2010; 115:4039-42
    • (2010) Blood , vol.115 , pp. 4039-4042
    • Carette, J.E.1    Pruszak, J.2    Varadarjan, M.3
  • 50
    • 76249133692 scopus 로고    scopus 로고
    • Defined factors induce reprogramming of gastrointestinal cancer cells
    • Miyoshi N, Ishii H, Nagai K et al. Defined factors induce reprogramming of gastrointestinal cancer cells. Proc Natl Acad Sci USA 2010; 107:40-5
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 40-45
    • Miyoshi, N.1    Ishii, H.2    Nagai, K.3
  • 51
    • 73449100783 scopus 로고    scopus 로고
    • Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells
    • Si-Tayeb K, Noto FK, Nagaoka M et al. Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology 2010; 51:297-305
    • (2010) Hepatology , vol.51 , pp. 297-305
    • Si-Tayeb, K.1    Noto, F.K.2    Nagaoka, M.3
  • 52
    • 70349437501 scopus 로고    scopus 로고
    • Generation of pluripotent stem cells from patients with type 1 diabetes
    • Maehr R, Chen S, Snitow M et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proc Natl Acad Sci USA 2009; 106:15768-73
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 15768-15773
    • Maehr, R.1    Chen, S.2    Snitow, M.3
  • 53
    • 39149129085 scopus 로고    scopus 로고
    • Stem cells and drug discovery: The beginning of a new era?
    • Rubin LL. Stem cells and drug discovery: the beginning of a new era? Cell 2008; 132:549-52
    • (2008) Cell , vol.132 , pp. 549-552
    • Rubin, L.L.1
  • 54
    • 37549030199 scopus 로고    scopus 로고
    • Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
    • Hanna J, Wernig M, Markoulaki S et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 2007; 318:1920-3
    • (2007) Science , vol.318 , pp. 1920-1923
    • Hanna, J.1    Wernig, M.2    Markoulaki, S.3
  • 55
    • 0030715611 scopus 로고    scopus 로고
    • Serial transplantation reveals the stem-cell- like regenerative potential of adult mouse hepatocytes
    • Overturf K, al-Dhalimy M, Ou CN et al. Serial transplantation reveals the stem-cell- like regenerative potential of adult mouse hepatocytes. Am J Pathol 1997; 151:1273-80
    • (1997) Am J Pathol , vol.151 , pp. 1273-1280
    • Overturf, K.1    Al-Dhalimy, M.2    Ou, C.N.3
  • 56
    • 0028353410 scopus 로고
    • Replacement of diseased mouse liver by hepatic cell transplantation
    • Rhim JA, Sandgren EP, Degen JL et al. Replacement of diseased mouse liver by hepatic cell transplantation. Science 1994; 263:1149-52
    • (1994) Science , vol.263 , pp. 1149-1152
    • Rhim, J.A.1    Sandgren, E.P.2    Degen, J.L.3
  • 57
    • 0025781894 scopus 로고
    • Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene
    • Sandgren EP, Palmiter RD, Heckel JL et al. Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene. Cell 1991; 66:245-56
    • (1991) Cell , vol.66 , pp. 245-256
    • Sandgren, E.P.1    Palmiter, R.D.2    Heckel, J.L.3
  • 59
    • 77953914634 scopus 로고    scopus 로고
    • Progress and promise towards safe induced pluripotent stem cells for therapy
    • Seifinejad A, Tabebordbar M, Baharvand H et al. Progress and promise towards safe induced pluripotent stem cells for therapy. Stem Cell Rev and Rep 2010; 6:297-306
    • (2010) Stem Cell Rev and Rep , vol.6 , pp. 297-306
    • Seifinejad, A.1    Tabebordbar, M.2    Baharvand, H.3
  • 60
    • 67049164945 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells from human blood
    • Loh YH, Agarwal S, Park IH et al. Generation of induced pluripotent stem cells from human blood. Blood 2009; 113:5476-9
    • (2009) Blood , vol.113 , pp. 5476-5479
    • Loh, Y.H.1    Agarwal, S.2    Park, I.H.3
  • 61
    • 77957671912 scopus 로고    scopus 로고
    • Reprogramming of human peripheral blood cells to induced pluripotent stem cell
    • Staerk J, Dawlaty MM, Gao Q et al. Reprogramming of human peripheral blood cells to induced pluripotent stem cell. Cell Stem Cell 2010; 7:20-4
    • (2010) Cell Stem Cell , vol.7 , pp. 20-24
    • Staerk, J.1    Dawlaty, M.M.2    Gao, Q.3
  • 62
    • 78650977507 scopus 로고    scopus 로고
    • Direct generation of induced pluripotent stem cells from human nonmobilized blood
    • [Epub ahead of print]
    • Kunisato A, Wakatsuki M, Shinba H et al. Direct generation of induced pluripotent stem cells from human nonmobilized blood. Stem Cells Dev 2010; [Epub ahead of print]
    • (2010) Stem Cells Dev
    • Kunisato, A.1    Wakatsuki, M.2    Shinba, H.3
  • 63
    • 77957671713 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells from human terminally differentiated circulation T cells
    • Seki T, Yuasa S, Oda M et al. Generation of induced pluripotent stem cells from human terminally differentiated circulation T cells. Cell Stem Cell 2010; 7:11-4
    • (2010) Cell Stem Cell , vol.7 , pp. 11-14
    • Seki, T.1    Yuasa, S.2    Oda, M.3
  • 64
    • 77955332631 scopus 로고    scopus 로고
    • Derivation of induced pluripotent stem cells from human peripheral blood T lymphocytes
    • Brown ME, Rondon E, Rajesh D et al. Derivation of induced pluripotent stem cells from human peripheral blood T lymphocytes. PLos One 2010; 5:e11373
    • (2010) PLos One , vol.5
    • Brown, M.E.1    Rondon, E.2    Rajesh, D.3
  • 65
    • 77957658573 scopus 로고    scopus 로고
    • Reprogramming of T cells from human peripheral blood
    • Loh YH, Hartung O, Li H et al. Reprogramming of T cells from human peripheral blood. Cell Stem Cell 2010; 7:15-9
    • (2010) Cell Stem Cell , vol.7 , pp. 15-19
    • Loh, Y.H.1    Hartung, O.2    Li, H.3
  • 66
    • 70349452213 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells from human cord blood
    • Haase A, Olmer R, Schwanke K et al. Generation of induced pluripotent stem cells from human cord blood. Cell Stem Cell 2009; 5:434-41
    • (2009) Cell Stem Cell , vol.5 , pp. 434-441
    • Haase, A.1    Olmer, R.2    Schwanke, K.3
  • 67
    • 69349089552 scopus 로고    scopus 로고
    • Differentiation stage determines potential of hematopoietic cells fro reprogramming into induced pluripotent stem cells
    • Eminli S, Foudi A, Stadtfeld M et al. Differentiation stage determines potential of hematopoietic cells fro reprogramming into induced pluripotent stem cells. Nat Genet 2009; 41:968-76
    • (2009) Nat Genet , vol.41 , pp. 968-976
    • Eminli, S.1    Foudi, A.2    Stadtfeld, M.3
  • 68
    • 70349309622 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2
    • Giorgetti A, Montserrat N, Aasen T et al. Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2. Cell Stem Cell 2009; 5:353-57
    • (2009) Cell Stem Cell , vol.5 , pp. 353-357
    • Giorgetti, A.1    Montserrat, N.2    Aasen, T.3
  • 69
    • 77649252315 scopus 로고    scopus 로고
    • Human and mouse adipose- derived cells support feeder-independent induction of pluripotent stem cells
    • Sugii S, Kida Y, Kawamura T et al. Human and mouse adipose- derived cells support feeder-independent induction of pluripotent stem cells. Proc Natl Acad Sci USA 2010; 107:3558-63
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 3558-3563
    • Sugii, S.1    Kida, Y.2    Kawamura, T.3
  • 70
    • 77954462722 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells from human adipose-derived stem cells without c-MYC
    • Aoki T, Ohnishi H, Oda Y et al. Generation of induced pluripotent stem cells from human adipose-derived stem cells without c-MYC. Tissue Eng Part A 2010; 16:2197-206
    • (2010) Tissue Eng Part A , vol.16 , pp. 2197-2206
    • Aoki, T.1    Ohnishi, H.2    Oda, Y.3
  • 71
    • 77956510690 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from human third molar mesenchymal stromal cells
    • Oda Y, Yoshimura Y, Ohnishi H et al. Induction of pluripotent stem cells from human third molar mesenchymal stromal cells. J Biol Chem 2010; 285:29270-8
    • (2010) J Biol Chem , vol.285 , pp. 29270-29278
    • Oda, Y.1    Yoshimura, Y.2    Ohnishi, H.3
  • 72
    • 55749089875 scopus 로고    scopus 로고
    • Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
    • Aasen T, Raya A, Barrero MJ et al. Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol 2008; 26:1276-84
    • (2008) Nat Biotechnol , vol.26 , pp. 1276-1284
    • Aasen, T.1    Raya, A.2    Barrero, M.J.3
  • 73
    • 70349687407 scopus 로고    scopus 로고
    • Direct reprogramming of human neural stem cells by OCT4
    • Kim JB, Greber B, Arauzo-Bravo MJ et al. Direct reprogramming of human neural stem cells by OCT4. Nature 2009; 461:649-53
    • (2009) Nature , vol.461 , pp. 649-653
    • Kim, J.B.1    Greber, B.2    Arauzo-Bravo, M.J.3
  • 74
    • 70350380887 scopus 로고    scopus 로고
    • Sox2 is dispensible for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells
    • Utikal J, Maherali N, Kulalert W et al. Sox2 is dispensible for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells. J Cell Sci 2009; 122:3502-10
    • (2009) J Cell Sci , vol.122 , pp. 3502-3510
    • Utikal, J.1    Maherali, N.2    Kulalert, W.3
  • 75
    • 78650051022 scopus 로고    scopus 로고
    • Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader Willi syndrom
    • [Epub ahead of print]
    • Yang J, Cai J, Zhang Y et al. Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader Willi syndrom. J Biol Chem 2010; [Epub ahead of print]
    • (2010) J Biol Chem
    • Yang, J.1    Cai, J.2    Zhang, Y.3


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