Cardiomyocytes derived from human embryonic stem cells - Characteristics and utility for drug discovery

Current Opinion in Drug Discovery and Development

Volumn 12, Issue 1, 2009, Pages 133-140

  Steel, D ^a   Hyllner, J ^a   Sartipy, P ^a  

^a Cellartis AB   (Sweden)

Author keywords

Cardiomyocytes; Differentiation; Drug discovery; Human embryonic stem cells; Safety assessment

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; ALPHA ADRENERGIC RECEPTOR; ASTEMIZOLE; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; BETA ADRENERGIC RECEPTOR; BONE MORPHOGENETIC PROTEIN; CALCIUM CHANNEL; CISAPRIDE; DOFETILIDE; FIBROBLAST GROWTH FACTOR; HEPTANOL; LIDOCAINE; MUSCARINIC RECEPTOR; POTASSIUM CHANNEL; QUINIDINE; SODIUM CHANNEL; SOTALOL; TRANSCRIPTION FACTOR GATA; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTOR TBX5; WNT PROTEIN;

CARDIOTOXICITY; CELL DIFFERENTIATION; DRUG SAFETY; DUCHENNE MUSCULAR DYSTROPHY; ELECTROPHYSIOLOGY; EMBRYONIC STEM CELL; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HEART ARRHYTHMIA; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MAGNETIC SEPARATION; QT PROLONGATION; REVIEW; RISK ASSESSMENT; SCALE UP; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

CELL DIFFERENTIATION; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ELECTROPHYSIOLOGY; EMBRYONIC STEM CELLS; HUMANS; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; PLURIPOTENT STEM CELLS;

EID: 58449092608     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (32)

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