Neuroprotective features of mesenchymal stem cells

Best Practice and Research: Clinical Haematology

Volumn 24, Issue 1, 2011, Pages 59-64

  Uccelli, Antonio ^a,b   Benvenuto, Federica ^a   Laroni, Alice ^a   Giunti, Debora ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b Advanced Biotechnology Center ABC   (Italy)

Author keywords

central nervous system (CNS): neurons; experimental autoimmune encephalomyelitis (EAE); mesenchymal stem cells (MSC); microglia; neuroprotection; oligodendrocytes

Indexed keywords

ALLERGIC ENCEPHALOMYELITIS; ARTICLE; AUTOIMMUNITY; BONE MARROW CELL; CENTRAL NERVOUS SYSTEM; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNOMODULATION; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MICROGLIA; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD INJURY; STROKE;

EID: 79952585505     PISSN: 15216926     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.beha.2011.01.004     Document Type: Review

References (41)

1. A.J. Friedenstein, R.K. Chailakhyan, and N.V. Latsinik Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo Transplantation 17 4 1974 331 340
2. A. Wilson, and A. Trumpp Bone-marrow haematopoietic-stem-cell niches Nat Rev Immunol 6 2 2006 93 106 (Pubitemid 43361585)
3. S. Mendez-Ferrer, T.V. Michurina, and F. Ferraro Mesenchymal and haematopoietic stem cells form a unique bone marrow niche Nature 466 7308 2010 829 834
4. S. Jones, N. Horwood, A. Cope, and F. Dazzi The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells J Immunol 179 5 2007 2824 2831
5. C. Campagnoli, I.A. Roberts, and S. Kumar Identification of mesenchymal stem/progenitor cells in human first- trimester fetal blood, liver, and bone marrow Blood 98 8 2001 2396 2402
6. N. Sessarego, A. Parodi, and M. Podesta Multipotent mesenchymal stromal cells from amniotic fluid: solid perspectives for clinical application Haematologica 93 3 2008 339 346 (Pubitemid 351398634)
7. L.d.S. Meirelles, P.C. Chagastelles, and N.B. Nardi Mesenchymal stem cells reside in virtually all post-natal organs and tissues J Cell Sci 119 11 2006 2204 2213 (Pubitemid 43960310)
8. M.F. Pittenger, A.M. Mackay, and S.C. Beck Multilineage potential of adult human mesenchymal stem cells Science 284 5411 1999 143 147 (Pubitemid 29282067)
9. P.A. Sotiropoulou, S.A. Perez, and A.D. Gritzapis Interactions Between Human Mesenchymal Stem Cells and Natural Killer Cells Stem Cells 24 1 2006 74 85
10. A. Uccelli, L. Moretta, and V. Pistoia Mesenchymal stem cells in health and disease Nat Rev Immunol 8 9 2008 726 736
11. G.C. Kopen, D.J. Prockop, and D.G. Phinney Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains Proc Natl Acad Sci USA 96 19 1999 10711 10716 (Pubitemid 29442209)
12. S.M. Devine, C. Cobbs, and M. Jennings Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into non-human primates Blood 101 8 2003 2999 3001 (Pubitemid 36857986)
13. E. Zappia, S. Casazza, and E. Pedemonte Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T cell anergy Blood 106 5 2005 1755 1761 (Pubitemid 41208591)
14. E. Gerdoni, B. Gallo, and S. Casazza Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis Ann Neurol 61 3 2007 219 227 (Pubitemid 46557346)
15. J. Zhang, Y. Li, and J. Chen Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice Exp Neurol 195 1 2005 16 26 (Pubitemid 41116810)
16. G. Constantin, S. Marconi, and B. Rossi Adipose-Derived Mesenchymal Stem Cells Ameliorate Chronic Experimental Autoimmune Encephalomyelitis Stem Cells 27 2009 11
17. L. Bai, D.P. Lennon, and V. Eaton Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis Glia 57 11 2009 1192 1203
18. D.G. Phinney, and D.J. Prockop Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair-current views Stem Cells 25 11 2007 2896 2902 (Pubitemid 350127874)
19. D.G. Phinney, K. Hill, and C. Michelson Biological activities encoded by the murine mesenchymal stem cell transcriptome provide a basis for their developmental potential and broad therapeutic efficacy Stem Cells 24 1 2006 186 198
20. R.H. Lee, A.A. Pulin, and M.J. Seo Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6 Cell Stem Cell 5 1 2009 54 63
21. B. Parekkadan, D. van Poll, and K. Suganuma Mesenchymal stem cell-derived molecules reverse fulminant hepatic failure PLoS ONE 2 9 2007 e941
22. A. Scuteri, A. Cassetti, and G. Tredici Adult mesenchymal stem cells rescue dorsal root ganglia neurons from dying Brain Res 1116 1 2006 75 81 (Pubitemid 44485016)
23. L. Crigler, R.C. Robey, and A. Asawachaicharn Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis Exp Neurol 198 1 2006 54 64 (Pubitemid 43243744)
24. A. Wilkins, K. Kemp, and M. Ginty Human bone marrow-derived mesenchymal stem cells secrete brain-derived neurotrophic factor which promotes neuronal survival in vitro Stem cell res 3 1 2009 63 70
25. J. Zhang, Y. Li, and M. Lu Bone marrow stromal cells reduce axonal loss in experimental autoimmune encephalomyelitis mice J neurosci res 84 3 2006 587 595 (Pubitemid 44196699)
26. I. Kassis, N. Grigoriadis, and B. Gowda-Kurkalli Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitis Arch Neurol 65 6 2008 753 761 (Pubitemid 351831453)
27. Y. Akiyama, C. Radtke, O. Honmou, and J.D. Kocsis Remyelination of the spinal cord following intravenous delivery of bone marrow cells Glia 39 3 2002 229 236
28. K. Satake, J. Lou, and L.G. Lenke Migration of mesenchymal stem cells through cerebrospinal fluid into injured spinal cord tissue Spine 29 18 2004 1971 1979 (Pubitemid 40202267)
29. A. Vercelli, O.M. Mereuta, and D. Garbossa Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis Neurobiol disease 31 3 2008 395 405
30. J. Chen, Y. Li, and M. Katakowski Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat J neurosci res 73 6 2003 778 786 (Pubitemid 37071731)
31. A.I. Caplan, and J.E. Dennis Mesenchymal stem cells as trophic mediators J cellular biochem 98 5 2006 1076 1084 (Pubitemid 44128350)
32. Y. Li, J. Chen, and X.G. Chen Human marrow stromal cell therapy for stroke in rat: Neurotrophins and functional recovery Neurology 59 2002 514 523 (Pubitemid 34919983)
33. J.R. Munoz, B.R. Stoutenger, and A.P. Robinson Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice Proc Natl Acad Sci USA 102 50 2005 18171 18176 (Pubitemid 41798520)
34. H. Ohtaki, J.H. Ylostalo, and J.E. Foraker Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses Proc Natl Acad Sci USA 105 38 2008 14638 14643
35. C. Zhou, C. Zhang, and S. Chi Effects of human marrow stromal cells on activation of microglial cells and production of inflammatory factors induced by lipopolysaccharide Brain res 1269 2009 23 30
36. F.J. Rivera, S. Couillard-Despres, and X. Pedre Mesenchymal stem cells instruct oligodendrogenic fate decision on adult neural stem cells Stem Cells 24 10 2006 2209 2219 (Pubitemid 44527474)
37. Y.J. Kim, H.J. Park, and G. Lee Neuroprotective effects of human mesenchymal stem cells on dopaminergic neurons through anti-inflammatory action Glia 57 1 2009 13 23
38. C. Lanza, S. Morando, and A. Voci Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivo J neurochem 110 5 2009 1674 1684
39. L. Bai, A. Caplan, D. Lennon, and R.H. Miller Human mesenchymal stem cells signals regulate neural stem cell fate Neurochem res 32 2 2007 353 362 (Pubitemid 46238881)
40. K. Le Blanc, F. Frassoni, and L. Ball Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study The Lancet 371 9624 2008 1579 1586 (Pubitemid 351626841)
41. O.N. Koc, S.L. Gerson, and B.W. Cooper Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy J Clin Oncol 18 2 2000 307 316 (Pubitemid 30056419)