Expression and induction of CYP2C P450 enzymes in primary cultures of human hepatocytes

Journal of Pharmacology and Experimental Therapeutics

Volumn 302, Issue 2, 2002, Pages 475-482

  Raucy, Judy L ^a,b,c   Mueller, Lisa ^a,b,c   Duan, Kui ^a,b,c   Allen, Scott W ^a,b,c   Strom, Stephen ^a,b,c   Lasker, Jerome M ^a,b,c  

^a LA JOLLA INSTITUTE FOR MOLECULAR MEDICINE   (United States)

^b HACKENSACK UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANE RECEPTOR; CELL NUCLEUS RECEPTOR; COLLAGEN; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; CYTOCHROME P450 ISOENZYME; DEXAMETHASONE; MESSENGER RNA; ORPHAN NUCLEAR RECEPTOR; PHENOBARBITAL; PREGNANE X RECEPTOR; RIFAMPICIN; STEROID; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CELL LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DNA RESPONSIVE ELEMENT; DRUG POTENCY; DRUG TRANSFORMATION; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; HUMAN; HUMAN CELL; LIVER CELL CULTURE; MALE; NORTHERN BLOTTING; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RIBONUCLEASE PROTECTION ASSAY; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ADULT; AGED; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOCYTES; HISPANIC AMERICANS; HUMANS; ISOENZYMES; MALE; MIDDLE AGED; PENNSYLVANIA; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0036073284     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.033837     Document Type: Article

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