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Volumn 76, Issue 2, 2012, Pages 383-404

Subversion of host recognition and defense systems by Francisella spp.

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBODY; BETA LACTAM ANTIBIOTIC; CATHELICIDIN; COMPLEMENT; COMPLEMENT MEMBRANE ATTACK COMPLEX; GAMMA INTERFERON; HEPCIDIN; QUINOLONE; REACTIVE OXYGEN METABOLITE; TETRACYCLINE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9;

EID: 84862521854     PISSN: 10922172     EISSN: 10985557     Source Type: Journal    
DOI: 10.1128/MMBR.05027-11     Document Type: Review
Times cited : (110)

References (244)
  • 1
    • 70949098358 scopus 로고    scopus 로고
    • TLR-dependent control of Francisella tularensis infection and host inflammatory responses
    • Abplanalp AL, Morris IR, Parida BK, Teale JM, Berton MT. 2009. TLR-dependent control of Francisella tularensis infection and host inflammatory responses. PLoS One 4:e7920.
    • (2009) PLoS One , vol.4
    • Abplanalp, A.L.1    Morris, I.R.2    Parida, B.K.3    Teale, J.M.4    Berton, M.T.5
  • 2
    • 84862547485 scopus 로고    scopus 로고
    • Francisella-arthropod vector interaction and its role in patho-adaptation to infect mammals
    • Akimana C, Kwaik Y. 2011. Francisella-arthropod vector interaction and its role in patho-adaptation to infect mammals. Front. Microbiol. 2:34.
    • (2011) Front. Microbiol. , vol.2 , pp. 34
    • Akimana, C.1    Kwaik, Y.2
  • 3
    • 59249084463 scopus 로고    scopus 로고
    • Glutathione provides a source of cysteine essential for intracellular multiplication of Francisella tularensis
    • Alkhuder K, Meibom KL, Dubail I, Dupuis M, Charbit A. 2009. Glutathione provides a source of cysteine essential for intracellular multiplication of Francisella tularensis. PLoS Pathog. 5:e1000284.
    • (2009) PLoS Pathog. , vol.5
    • Alkhuder, K.1    Meibom, K.L.2    Dubail, I.3    Dupuis, M.4    Charbit, A.5
  • 4
    • 14844355257 scopus 로고    scopus 로고
    • Helicobacter pylori disrupts NADPH oxidase targeting in human neutrophils to induce extracellular superoxide release
    • Allen LA, Beecher BR, Lynch JT, Rohner OV, Wittine LM. 2005. Helicobacter pylori disrupts NADPH oxidase targeting in human neutrophils to induce extracellular superoxide release. J. Immunol. 174:3658-3667.
    • (2005) J. Immunol. , vol.174 , pp. 3658-3667
    • Allen, L.A.1    Beecher, B.R.2    Lynch, J.T.3    Rohner, O.V.4    Wittine, L.M.5
  • 5
    • 77952743439 scopus 로고    scopus 로고
    • Antimicrobial and antibiofilm activity of cathelicidins and short, synthetic peptides against Francisella
    • Amer LS, Bishop BM, van Hoek ML. 2010. Antimicrobial and antibiofilm activity of cathelicidins and short, synthetic peptides against Francisella. Biochem. Biophys. Res. Commun. 396:246-251.
    • (2010) Biochem. Biophys. Res. Commun. , vol.396 , pp. 246-251
    • Amer, L.S.1    Bishop, B.M.2    Van Hoek, M.L.3
  • 6
    • 0030013036 scopus 로고    scopus 로고
    • Inability of the Francisella tularensis lipopolysaccharide to mimic or to antagonize the induction of cell activation by endotoxins
    • Ancuta P, Pedron T, Girard R, Sandstrom G, Chaby R. 1996. Inability of the Francisella tularensis lipopolysaccharide to mimic or to antagonize the induction of cell activation by endotoxins. Infect. Immun. 64:2041-2046.
    • (1996) Infect. Immun. , vol.64 , pp. 2041-2046
    • Ancuta, P.1    Pedron, T.2    Girard, R.3    Sandstrom, G.4    Chaby, R.5
  • 7
    • 33645096658 scopus 로고    scopus 로고
    • Transcriptional profiling of host responses in mouse lungs following aerosol infection with type A Francisella tularensis
    • Andersson H, et al. 2006. Transcriptional profiling of host responses in mouse lungs following aerosol infection with type A Francisella tularensis. J. Med. Microbiol. 55:263-271.
    • (2006) J. Med. Microbiol. , vol.55 , pp. 263-271
    • Andersson, H.1
  • 8
    • 0023719852 scopus 로고
    • Influence of genetic background on host resistance to experimental murine tularemia
    • Anthony LS, Skamene E, Kongshavn PA. 1988. Influence of genetic background on host resistance to experimental murine tularemia. Infect. Immun. 56:2089-2093.
    • (1988) Infect. Immun. , vol.56 , pp. 2089-2093
    • Anthony, L.S.1    Skamene, E.2    Kongshavn, P.A.3
  • 9
    • 77955411445 scopus 로고    scopus 로고
    • Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis
    • Apicella MA, et al. 2010. Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis. PLoS One 5:e11060.
    • (2010) PLoS One , vol.5
    • Apicella, M.A.1
  • 10
    • 33746881453 scopus 로고    scopus 로고
    • Macrophage nutriprive antimicrobial mechanisms
    • Appelberg R. 2006. Macrophage nutriprive antimicrobial mechanisms. J. Leukoc. Biol. 79:1117-1128.
    • (2006) J. Leukoc. Biol. , vol.79 , pp. 1117-1128
    • Appelberg, R.1
  • 11
    • 77955249234 scopus 로고    scopus 로고
    • Molecular complexity orchestrates modulation of phagosome biogenesis and escape to the cytosol of macrophages by Francisella tularensis
    • Asare R, Abu Kwaik Y. 2010. Molecular complexity orchestrates modulation of phagosome biogenesis and escape to the cytosol of macrophages by Francisella tularensis. Environ. Microbiol. 12:2559-2586.
    • (2010) Environ. Microbiol. , vol.12 , pp. 2559-2586
    • Asare, R.1    Abu Kwaik, Y.2
  • 12
    • 67649813204 scopus 로고    scopus 로고
    • Binding and cellular activation studies reveal that Toll-like receptor 2 can differentially recognize peptidoglycan from Gram-positive and Gram-negative bacteria
    • Asong J, Wolfert MA, Maiti KK, Miller D, Boons GJ. 2009. Binding and cellular activation studies reveal that Toll-like receptor 2 can differentially recognize peptidoglycan from Gram-positive and Gram-negative bacteria. J. Biol. Chem. 284:8643-8653.
    • (2009) J. Biol. Chem. , vol.284 , pp. 8643-8653
    • Asong, J.1    Wolfert, M.A.2    Maiti, K.K.3    Miller, D.4    Boons, G.J.5
  • 13
    • 80655125021 scopus 로고    scopus 로고
    • Francisella tularensis reveals a disparity between human and mouse NLRP3 inflammasome activation
    • Atianand MK, et al. 2011. Francisella tularensis reveals a disparity between human and mouse NLRP3 inflammasome activation. J. Biol. Chem. 286:39033-39042.
    • (2011) J. Biol. Chem. , vol.286 , pp. 39033-39042
    • Atianand, M.K.1
  • 14
    • 0036830796 scopus 로고    scopus 로고
    • The leukocyte NADPH oxidase
    • Babior BM. 2002. The leukocyte NADPH oxidase. Isr. Med. Assoc. J. 4:1023-1024.
    • (2002) Isr. Med. Assoc. J. , vol.4 , pp. 1023-1024
    • Babior, B.M.1
  • 15
    • 50849117147 scopus 로고    scopus 로고
    • An improved vaccine for prevention of respiratory tularemia caused by Francisella tularensis SchuS4 strain
    • Bakshi CS, et al. 2008. An improved vaccine for prevention of respiratory tularemia caused by Francisella tularensis SchuS4 strain. Vaccine 26:5276-5288.
    • (2008) Vaccine , vol.26 , pp. 5276-5288
    • Bakshi, C.S.1
  • 16
    • 33749019466 scopus 로고    scopus 로고
    • Superoxide dismutase B gene (sodB)-deficient mutants of Francisella tularensis demonstrate hypersensitivity to oxidative stress and attenuated virulence
    • Bakshi CS, et al. 2006. Superoxide dismutase B gene (sodB)-deficient mutants of Francisella tularensis demonstrate hypersensitivity to oxidative stress and attenuated virulence. J. Bacteriol. 188:6443-6448.
    • (2006) J. Bacteriol. , vol.188 , pp. 6443-6448
    • Bakshi, C.S.1
  • 17
    • 33748079800 scopus 로고    scopus 로고
    • Characterization of the receptor-ligand pathways important for entry and survival of Francisella tularensis in human macrophages
    • Balagopal A, et al. 2006. Characterization of the receptor-ligand pathways important for entry and survival of Francisella tularensis in human macrophages. Infect. Immun. 74:5114-5125.
    • (2006) Infect. Immun. , vol.74 , pp. 5114-5125
    • Balagopal, A.1
  • 18
    • 79955527898 scopus 로고    scopus 로고
    • Isolation and mutagenesis of a capsule-like complex (CLC) from Francisella tularensis, and contribution of the CLC to F. tularensis virulence in mice
    • Bandara AB, et al. 2011. Isolation and mutagenesis of a capsule-like complex (CLC) from Francisella tularensis, and contribution of the CLC to F. tularensis virulence in mice. PLoS One 6:e19003.
    • (2011) PLoS One , vol.6
    • Bandara, A.B.1
  • 19
    • 52649094980 scopus 로고    scopus 로고
    • A novel receptor-ligand pathway for entry of Francisella tularensis in monocyte-like THP-1 cells: Interaction between surface nucleolin and bacterial elongation factor Tu
    • Barel M, et al. 2008. A novel receptor-ligand pathway for entry of Francisella tularensis in monocyte-like THP-1 cells: interaction between surface nucleolin and bacterial elongation factor Tu. BMC Microbiol. 8:145.
    • (2008) BMC Microbiol. , vol.8 , pp. 145
    • Barel, M.1
  • 20
    • 67650556147 scopus 로고    scopus 로고
    • The role of complement opsonization in interactions between F. tularensis subsp. novicida and human neutrophils
    • Barker JH, et al. 2009. The role of complement opsonization in interactions between F. tularensis subsp. novicida and human neutrophils. Microbes Infect. 11:762-769.
    • (2009) Microbes Infect. , vol.11 , pp. 762-769
    • Barker, J.H.1
  • 21
    • 72049089849 scopus 로고    scopus 로고
    • The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence
    • Barker JR, et al. 2009. The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence. Mol. Microbiol. 74:1459-1470.
    • (2009) Mol. Microbiol. , vol.74 , pp. 1459-1470
    • Barker, J.R.1
  • 22
    • 0032790677 scopus 로고    scopus 로고
    • The respiratory burst-inhibiting acid phosphatase AcpA is not essential for the intramacrophage growth or virulence of Francisella novicida
    • Baron GS, Reilly TJ, Nano FE. 1999. The respiratory burst-inhibiting acid phosphatase AcpA is not essential for the intramacrophage growth or virulence of Francisella novicida. FEMS Microbiol. Lett. 176:85-90.
    • (1999) FEMS Microbiol. Lett. , vol.176 , pp. 85-90
    • Baron, G.S.1    Reilly, T.J.2    Nano, F.E.3
  • 23
    • 4644351584 scopus 로고    scopus 로고
    • AcrAB-TolC directs efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium DT104
    • Baucheron S, et al. 2004. AcrAB-TolC directs efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium DT104. Antimicrob. Agents Chemother. 48:3729-3735.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3729-3735
    • Baucheron, S.1
  • 24
    • 80051920695 scopus 로고    scopus 로고
    • IFN-beta mediates suppression of IL-12p40 in human dendritic cells following infection with virulent Francisella tularensis
    • Bauler TJ, Chase JC, Bosio CM. 2011. IFN-beta mediates suppression of IL-12p40 in human dendritic cells following infection with virulent Francisella tularensis. J. Immunol. 187:1845-1855.
    • (2011) J. Immunol. , vol.187 , pp. 1845-1855
    • Bauler, T.J.1    Chase, J.C.2    Bosio, C.M.3
  • 25
    • 84858419544 scopus 로고    scopus 로고
    • A variety of novel lipid a structures obtained from Francisella tularensis live obtained from Francisella tularensis live
    • Beasley AS, et al. 2012. A variety of novel lipid a structures obtained from Francisella tularensis live obtained from Francisella tularensis live. Innate Immun. 18:268-278.
    • (2012) Innate Immun. , vol.18 , pp. 268-278
    • Beasley, A.S.1
  • 26
    • 0028024570 scopus 로고
    • Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence
    • Beatty WL, Belanger TA, Desai AA, Morrison RP, Byrne GI. 1994. Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence. Infect. Immun. 62:3705-3711.
    • (1994) Infect. Immun. , vol.62 , pp. 3705-3711
    • Beatty, W.L.1    Belanger, T.A.2    Desai, A.A.3    Morrison, R.P.4    Byrne, G.I.5
  • 27
    • 0030828008 scopus 로고    scopus 로고
    • pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes
    • Beauregard KE, Lee KD, Collier RJ, Swanson JA. 1997. pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes. J. Exp. Med. 186:1159-1163.
    • (1997) J. Exp. Med. , vol.186 , pp. 1159-1163
    • Beauregard, K.E.1    Lee, K.D.2    Collier, R.J.3    Swanson, J.A.4
  • 28
    • 33751511700 scopus 로고    scopus 로고
    • Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells (DC): Uptake of Francisella leads to activation of immature DC and intracellular survival of the bacteria
    • Ben Nasr A, et al. 2006. Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells (DC): uptake of Francisella leads to activation of immature DC and intracellular survival of the bacteria. J. Leukoc. Biol. 80:774-786.
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 774-786
    • Ben Nasr, A.1
  • 29
    • 46949096670 scopus 로고    scopus 로고
    • Subversion of complement activation at the bacterial surface promotes serum resistance and opsonophagocytosis of Francisella tularensis
    • Ben Nasr A, Klimpel GR. 2008. Subversion of complement activation at the bacterial surface promotes serum resistance and opsonophagocytosis of Francisella tularensis. J. Leukoc. Biol. 84:77-85.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 77-85
    • Ben Nasr, A.1    Klimpel, G.R.2
  • 30
    • 38349144550 scopus 로고    scopus 로고
    • The AcrAB RND efflux system from the live vaccine strain of Francisella tularensis is a multiple drug efflux system that is required for virulence in mice
    • Bina XR, Lavine CL, Miller MA, Bina JE. 2008. The AcrAB RND efflux system from the live vaccine strain of Francisella tularensis is a multiple drug efflux system that is required for virulence in mice. FEMS Microbiol. Lett. 279:226-233.
    • (2008) FEMS Microbiol. Lett. , vol.279 , pp. 226-233
    • Bina, X.R.1    Lavine, C.L.2    Miller, M.A.3    Bina, J.E.4
  • 31
    • 77149151902 scopus 로고    scopus 로고
    • Francisella tularensis subsp. novicida isolated from a human in Arizona
    • Birdsell D, et al. 2009. Francisella tularensis subsp. novicida isolated from a human in Arizona. BMC Res. Notes 2:223.
    • (2009) BMC Res. Notes , vol.2 , pp. 223
    • Birdsell, D.1
  • 33
    • 33846526208 scopus 로고    scopus 로고
    • A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system
    • Boneca IG, et al. 2007. A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system. Proc. Natl. Acad. Sci. U. S. A. 104:997-1002.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 997-1002
    • Boneca, I.G.1
  • 34
    • 33947702199 scopus 로고    scopus 로고
    • Active suppression of the pulmonary immune response by Francisella tularensis Schu4
    • Bosio CM, Bielefeldt-Ohmann H, Belisle JT. 2007. Active suppression of the pulmonary immune response by Francisella tularensis Schu4. J. Immunol. 178:4538-4547.
    • (2007) J. Immunol. , vol.178 , pp. 4538-4547
    • Bosio, C.M.1    Bielefeldt-Ohmann, H.2    Belisle, J.T.3
  • 35
    • 27744547036 scopus 로고    scopus 로고
    • Francisella tularensis induces aberrant activation of pulmonary dendritic cells
    • Bosio CM, Dow SW. 2005. Francisella tularensis induces aberrant activation of pulmonary dendritic cells. J. Immunol. 175:6792-6801.
    • (2005) J. Immunol. , vol.175 , pp. 6792-6801
    • Bosio, C.M.1    Dow, S.W.2
  • 36
    • 0034975764 scopus 로고    scopus 로고
    • Iron uptake mechanisms and their regulation in pathogenic bacteria
    • Braun V. 2001. Iron uptake mechanisms and their regulation in pathogenic bacteria. Int. J. Med. Microbiol. 291:67-79.
    • (2001) Int. J. Med. Microbiol. , vol.291 , pp. 67-79
    • Braun, V.1
  • 38
    • 51449099913 scopus 로고    scopus 로고
    • Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion
    • Butchar JP, et al. 2008. Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion. PLoS One 3:e2924.
    • (2008) PLoS One , vol.3
    • Butchar, J.P.1
  • 39
    • 9244224674 scopus 로고    scopus 로고
    • Capsule polysaccharide mediates bacterial resistance
    • Campos M, et al. 2004. Capsule polysaccharide mediates bacterial resistance. Infect. Immun. 72:7107-7114.
    • (2004) Infect. Immun. , vol.72 , pp. 7107-7114
    • Campos, M.1
  • 40
    • 70350436281 scopus 로고    scopus 로고
    • Global transcriptional response to spermine, a component of the intramacrophage environment, reveals regulation of Francisella gene expression through insertion sequence elements
    • Carlson PE, Jr, et al. 2009. Global transcriptional response to spermine, a component of the intramacrophage environment, reveals regulation of Francisella gene expression through insertion sequence elements. J. Bacteriol. 191:6855-6864.
    • (2009) J. Bacteriol. , vol.191 , pp. 6855-6864
    • Carlson Jr., P.E.1
  • 42
    • 80053605687 scopus 로고    scopus 로고
    • Antimicrobial peptides important in innate immunity
    • Cederlund A, Gudmundsson G, Agerberth B. 2011. Antimicrobial peptides important in innate immunity. FEBS J. 278:3942-3951.
    • (2011) FEBS J. , vol.278 , pp. 3942-3951
    • Cederlund, A.1    Gudmundsson, G.2    Agerberth, B.3
  • 43
    • 67249166181 scopus 로고    scopus 로고
    • Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies
    • Champion MD, et al. 2009. Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies. PLoS Pathog. 5:e1000459.
    • (2009) PLoS Pathog. , vol.5
    • Champion, M.D.1
  • 44
    • 58449133177 scopus 로고    scopus 로고
    • Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4
    • Chase JC, Celli J, Bosio CM. 2009. Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4. Infect. Immun. 77:180-195.
    • (2009) Infect. Immun. , vol.77 , pp. 180-195
    • Chase, J.C.1    Celli, J.2    Bosio, C.M.3
  • 45
    • 33749264796 scopus 로고    scopus 로고
    • Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication
    • Checroun C, Wehrly TD, Fischer ER, Hayes SF, Celli J. 2006. Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication. Proc. Natl. Acad. Sci. U. S. A. 103:14578-14583.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 14578-14583
    • Checroun, C.1    Wehrly, T.D.2    Fischer, E.R.3    Hayes, S.F.4    Celli, J.5
  • 46
    • 5344281146 scopus 로고    scopus 로고
    • Toll-like receptor 4 (TLR4) does not confer a resistance advantage on mice against low-dose aerosol infection with virulent type A Francisella tularensis
    • Chen W, KuoLee R, Shen H, Busa M, Conlan JW. 2004. Toll-like receptor 4 (TLR4) does not confer a resistance advantage on mice against low-dose aerosol infection with virulent type A Francisella tularensis. Microb. Pathog. 37:185-191.
    • (2004) Microb. Pathog. , vol.37 , pp. 185-191
    • Chen, W.1    KuoLee, R.2    Shen, H.3    Busa, M.4    Conlan, J.W.5
  • 47
    • 11144303403 scopus 로고    scopus 로고
    • Toll-like receptor 4 (TLR4) plays a relatively minor role in murine defense against primary intradermal infection with Francisella tularensis LVS
    • Chen W, Kuolee R, Shen H, Busa M, Conlan JW. 2005. Toll-like receptor 4 (TLR4) plays a relatively minor role in murine defense against primary intradermal infection with Francisella tularensis LVS. Immunol. Lett. 97:151-154.
    • (2005) Immunol. Lett. , vol.97 , pp. 151-154
    • Chen, W.1    Kuolee, R.2    Shen, H.3    Busa, M.4    Conlan, J.W.5
  • 48
    • 73449139119 scopus 로고    scopus 로고
    • Acid phosphatases do not contribute to the pathogenesis of type A Francisella tularensis
    • Child R, Wehrly TD, Rockx-Brouwer D, Dorward DW, Celli J. 2010. Acid phosphatases do not contribute to the pathogenesis of type A Francisella tularensis. Infect. Immun. 78:59-67.
    • (2010) Infect. Immun. , vol.78 , pp. 59-67
    • Child, R.1    Wehrly, T.D.2    Rockx-Brouwer, D.3    Dorward, D.W.4    Celli, J.5
  • 49
    • 57349126161 scopus 로고    scopus 로고
    • The early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression
    • Chong A, et al. 2008. The early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression. Infect. Immun. 76:5488-5499.
    • (2008) Infect. Immun. , vol.76 , pp. 5488-5499
    • Chong, A.1
  • 50
    • 79959463532 scopus 로고    scopus 로고
    • Tryptophan prototrophy contributes to Francisella tularensis evasion of gamma interferon-mediated host defense
    • Chu P, Rodriguez AR, Arulanandam BP, Klose KE. 2011. Tryptophan prototrophy contributes to Francisella tularensis evasion of gamma interferon-mediated host defense. Infect. Immun. 79:2356-2361.
    • (2011) Infect. Immun. , vol.79 , pp. 2356-2361
    • Chu, P.1    Rodriguez, A.R.2    Arulanandam, B.P.3    Klose, K.E.4
  • 51
    • 54049154653 scopus 로고    scopus 로고
    • Evasion of complement-mediated lysis and complement C3 deposition are regulated by Francisella tularensis lipopolysaccharide O antigen
    • Clay CD, Soni S, Gunn JS, Schlesinger LS. 2008. Evasion of complement-mediated lysis and complement C3 deposition are regulated by Francisella tularensis lipopolysaccharide O antigen. J. Immunol. 181:5568-5578.
    • (2008) J. Immunol. , vol.181 , pp. 5568-5578
    • Clay, C.D.1    Soni, S.2    Gunn, J.S.3    Schlesinger, L.S.4
  • 52
    • 23944445646 scopus 로고    scopus 로고
    • Francisella tularensis enters macrophages via a novel process involving pseudopod loops
    • Clemens DL, Lee BY, Horwitz MA. 2005. Francisella tularensis enters macrophages via a novel process involving pseudopod loops. Infect. Immun. 73:5892-5902.
    • (2005) Infect. Immun. , vol.73 , pp. 5892-5902
    • Clemens, D.L.1    Lee, B.Y.2    Horwitz, M.A.3
  • 53
    • 65449134827 scopus 로고    scopus 로고
    • Francisella tularensis phagosomal escape does not require acidification of the phagosome
    • Clemens DL, Lee BY, Horwitz MA. 2009. Francisella tularensis phagosomal escape does not require acidification of the phagosome. Infect. Immun. 77:1757-1773.
    • (2009) Infect. Immun. , vol.77 , pp. 1757-1773
    • Clemens, D.L.1    Lee, B.Y.2    Horwitz, M.A.3
  • 54
    • 77949471780 scopus 로고    scopus 로고
    • Binding and activation of host plasminogen on the surface of Francisella tularensis
    • Clinton SR, Bina JE, Hatch TP, Whitt MA, Miller MA. 2010. Binding and activation of host plasminogen on the surface of Francisella tularensis. BMC Microbiol. 10:76.
    • (2010) BMC Microbiol. , vol.10 , pp. 76
    • Clinton, S.R.1    Bina, J.E.2    Hatch, T.P.3    Whitt, M.A.4    Miller, M.A.5
  • 55
    • 34547636340 scopus 로고    scopus 로고
    • Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophages
    • Cole LE, et al. 2007. Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophages. Infect. Immun. 75:4127-4137.
    • (2007) Infect. Immun. , vol.75 , pp. 4127-4137
    • Cole, L.E.1
  • 56
    • 33646472970 scopus 로고    scopus 로고
    • Myeloid differentiation factor-88 (MyD88) is essential for control of primary in vivo Francisella tularensis LVS infection, but not for control of intramacrophage bacterial replication
    • Collazo CM, Sher A, Meierovics AI, Elkins KL. 2006. Myeloid differentiation factor-88 (MyD88) is essential for control of primary in vivo Francisella tularensis LVS infection, but not for control of intramacrophage bacterial replication. Microbes Infect. 8:779-790.
    • (2006) Microbes Infect. , vol.8 , pp. 779-790
    • Collazo, C.M.1    Sher, A.2    Meierovics, A.I.3    Elkins, K.L.4
  • 57
    • 80051988391 scopus 로고    scopus 로고
    • Francisella infections in farmed and wild aquatic organisms
    • Colquhoun D, Duobu S. 2011. Francisella infections in farmed and wild aquatic organisms. Vet. Res. 42:47.
    • (2011) Vet. Res. , vol.42 , pp. 47
    • Colquhoun, D.1    Duobu, S.2
  • 58
    • 0037963150 scopus 로고    scopus 로고
    • Experimental tularemia in mice challenged by aerosol or intradermally with virulent strains of Francisella tularensis: Bacteriologic and histopathologic studies
    • Conlan JW, Chen W, Shen H, Webb A, KuoLee R. 2003. Experimental tularemia in mice challenged by aerosol or intradermally with virulent strains of Francisella tularensis: bacteriologic and histopathologic studies. Microb. Pathog. 34:239-248.
    • (2003) Microb. Pathog. , vol.34 , pp. 239-248
    • Conlan, J.W.1    Chen, W.2    Shen, H.3    Webb, A.4    KuoLee, R.5
  • 59
    • 70449715726 scopus 로고    scopus 로고
    • A novel role for plasmin-mediated degradation of opsonizing antibody in the evasion of host immunity by virulent, but not attenuated, Francisella tularensis
    • Crane DD, Warner SL, Bosio CM. 2009. A novel role for plasmin-mediated degradation of opsonizing antibody in the evasion of host immunity by virulent, but not attenuated, Francisella tularensis. J. Immunol. 183:4593-4600.
    • (2009) J. Immunol. , vol.183 , pp. 4593-4600
    • Crane, D.D.1    Warner, S.L.2    Bosio, C.M.3
  • 60
    • 58149458118 scopus 로고    scopus 로고
    • Francisella tularensis regulates autophagy-related host cell signaling pathways
    • Cremer TJ, Amer A, Tridandapani S, Butchar JP. 2009. Francisella tularensis regulates autophagy-related host cell signaling pathways. Autophagy 5:125-128.
    • (2009) Autophagy , vol.5 , pp. 125-128
    • Cremer, T.J.1    Amer, A.2    Tridandapani, S.3    Butchar, J.P.4
  • 61
    • 79960516624 scopus 로고    scopus 로고
    • Akt-mediated proinflammatory response of mononuclear phagocytes infected with Burkholderia cenocepacia occurs by a novel GSK3β-dependent, IκB kinase-independent mechanism
    • Cremer TJ, et al. 2011. Akt-mediated proinflammatory response of mononuclear phagocytes infected with Burkholderia cenocepacia occurs by a novel GSK3β-dependent, IκB kinase-independent mechanism. J. Immunol. 187:635-643.
    • (2011) J. Immunol. , vol.187 , pp. 635-643
    • Cremer, T.J.1
  • 62
    • 0031113955 scopus 로고    scopus 로고
    • A novel role for B cells in early protective immunity to an intracellular pathogen, Francisella tularensis strain LVS
    • Culkin SJ, Rhinehart-Jones T, Elkins KL. 1997. A novel role for B cells in early protective immunity to an intracellular pathogen, Francisella tularensis strain LVS. J. Immunol. 158:3277-3284.
    • (1997) J. Immunol. , vol.158 , pp. 3277-3284
    • Culkin, S.J.1    Rhinehart-Jones, T.2    Elkins, K.L.3
  • 63
    • 79961102157 scopus 로고    scopus 로고
    • Interleukin-10 and immunity against prokaryotic and eukaryotic intracellular pathogens
    • Cyktor JC, Turner J. 2011. Interleukin-10 and immunity against prokaryotic and eukaryotic intracellular pathogens. Infect. Immun. 79:2964-2973.
    • (2011) Infect. Immun. , vol.79 , pp. 2964-2973
    • Cyktor, J.C.1    Turner, J.2
  • 64
    • 82555195543 scopus 로고    scopus 로고
    • The biochemical properties of the Francisella pathogenicity island (FPI)-encoded proteins IglA, IglB, IglC, PdpB and DotU suggest roles in type VI secretion
    • de Bruin OM, et al. 2011. The biochemical properties of the Francisella pathogenicity island (FPI)-encoded proteins IglA, IglB, IglC, PdpB and DotU suggest roles in type VI secretion. Microbiology 157:3483-3491.
    • (2011) Microbiology , vol.157 , pp. 3483-3491
    • De Bruin, O.M.1
  • 65
    • 33846845100 scopus 로고    scopus 로고
    • The Francisella pathogenicity island protein IglA localizes to the bacterial cytoplasm and is needed for intracellular growth
    • de Bruin OM, Ludu JS, Nano FE. 2007. The Francisella pathogenicity island protein IglA localizes to the bacterial cytoplasm and is needed for intracellular growth. BMC Microbiol. 7:1.
    • (2007) BMC Microbiol. , vol.7 , pp. 1
    • De Bruin, O.M.1    Ludu, J.S.2    Nano, F.E.3
  • 66
    • 25444495693 scopus 로고    scopus 로고
    • The yin and yang of type I interferon activity in bacterial infection
    • Decker T, Muller M, Stockinger S. 2005. The yin and yang of type I interferon activity in bacterial infection. Nat. Rev. Immunol. 5:675-687.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 675-687
    • Decker, T.1    Muller, M.2    Stockinger, S.3
  • 67
    • 33745589524 scopus 로고    scopus 로고
    • Identification of Francisella tularensis genes affected by iron limitation
    • Deng K, Blick R, Liu W, Hansen E. 2006. Identification of Francisella tularensis genes affected by iron limitation. Infect. Immun. 74:4224-4236.
    • (2006) Infect. Immun. , vol.74 , pp. 4224-4236
    • Deng, K.1    Blick, R.2    Liu, W.3    Hansen, E.4
  • 68
    • 51949094409 scopus 로고    scopus 로고
    • Diverse myeloid and lymphoid cell subpopulations produce gamma interferon during early innate immune responses to Francisella tularensis live vaccine strain
    • De Pascalis R, Taylor BC, Elkins KL. 2008. Diverse myeloid and lymphoid cell subpopulations produce gamma interferon during early innate immune responses to Francisella tularensis live vaccine strain. Infect. Immun. 76:4311-4321.
    • (2008) Infect. Immun. , vol.76 , pp. 4311-4321
    • De Pascalis, R.1    Taylor, B.C.2    Elkins, K.L.3
  • 69
    • 67649607465 scopus 로고    scopus 로고
    • Autophagy, immunity, and microbial adaptations
    • Deretic V, Levine B. 2009. Autophagy, immunity, and microbial adaptations. Cell Host Microbe 5:527-549.
    • (2009) Cell Host Microbe , vol.5 , pp. 527-549
    • Deretic, V.1    Levine, B.2
  • 70
    • 33746903479 scopus 로고    scopus 로고
    • The protein secretion systems in Listeria: Inside out bacterial virulence
    • Desvaux M, Hébraud M. 2006. The protein secretion systems in Listeria: inside out bacterial virulence. FEMS Microbiol. Rev. 30:774-805.
    • (2006) FEMS Microbiol. Rev. , vol.30 , pp. 774-805
    • Desvaux, M.1    Hébraud, M.2
  • 71
    • 13244255402 scopus 로고    scopus 로고
    • Capsule synthesis by Bacillus anthracis is required for dissemination in murine inhalation anthrax
    • Drysdale M, et al. 2005. Capsule synthesis by Bacillus anthracis is required for dissemination in murine inhalation anthrax. EMBO J. 24:221-227.
    • (2005) EMBO J. , vol.24 , pp. 221-227
    • Drysdale, M.1
  • 72
    • 33646868832 scopus 로고    scopus 로고
    • Francisella tularensis LPS induces the production of cytokines in human monocytes and signals via Toll-like receptor 4 with much lower potency than E. coli LPS
    • Duenas AI, et al. 2006. Francisella tularensis LPS induces the production of cytokines in human monocytes and signals via Toll-like receptor 4 with much lower potency than E. coli LPS. Int. Immunol. 18:785-795.
    • (2006) Int. Immunol. , vol.18 , pp. 785-795
    • Duenas, A.I.1
  • 73
    • 23344449406 scopus 로고    scopus 로고
    • Staphylococcus aureus peptidoglycan is a Toll-like receptor 2 activator: A reevaluation
    • Dziarski R, Gupta D. 2005. Staphylococcus aureus peptidoglycan is a Toll-like receptor 2 activator: a reevaluation. Infect. Immun. 73:5212-5216.
    • (2005) Infect. Immun. , vol.73 , pp. 5212-5216
    • Dziarski, R.1    Gupta, D.2
  • 74
    • 76449110473 scopus 로고    scopus 로고
    • Restricted cytosolic growth of Francisella tularensis subsp. tularensis by IFN-gamma activation of macrophages
    • Edwards JA, Rockx-Brouwer D, Nair V, Celli J. 2010. Restricted cytosolic growth of Francisella tularensis subsp. tularensis by IFN-gamma activation of macrophages. Microbiology 156:327-339.
    • (2010) Microbiology , vol.156 , pp. 327-339
    • Edwards, J.A.1    Rockx-Brouwer, D.2    Nair, V.3    Celli, J.4
  • 75
    • 0036127059 scopus 로고    scopus 로고
    • In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70
    • Elkins KL, Cooper A, Colombini SM, Cowley SC, Kieffer TL. 2002. In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70. Infect. Immun. 70:1936-1948.
    • (2002) Infect. Immun. , vol.70 , pp. 1936-1948
    • Elkins, K.L.1    Cooper, A.2    Colombini, S.M.3    Cowley, S.C.4    Kieffer, T.L.5
  • 76
    • 0030055895 scopus 로고    scopus 로고
    • Minimal requirements for murine resistance to infection with Francisella tularensis LVS
    • Elkins KL, Rhinehart-Jones TR, Culkin SJ, Yee D, Winegar RK. 1996. Minimal requirements for murine resistance to infection with Francisella tularensis LVS. Infect. Immun. 64:3288-3293.
    • (1996) Infect. Immun. , vol.64 , pp. 3288-3293
    • Elkins, K.L.1    Rhinehart-Jones, T.R.2    Culkin, S.J.3    Yee, D.4    Winegar, R.K.5
  • 77
    • 0033558121 scopus 로고    scopus 로고
    • Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria
    • Elkins KL, Rhinehart-Jones TR, Stibitz S, Conover JS, Klinman DM. 1999. Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria. J. Immunol. 162:2291-2298.
    • (1999) J. Immunol. , vol.162 , pp. 2291-2298
    • Elkins, K.L.1    Rhinehart-Jones, T.R.2    Stibitz, S.3    Conover, J.S.4    Klinman, D.M.5
  • 78
    • 18744386097 scopus 로고    scopus 로고
    • IFN-gamma represses IL-4 expression via IRF-1 and IRF-2
    • Elser B, et al. 2002. IFN-gamma represses IL-4 expression via IRF-1 and IRF-2. Immunity 17:703-712.
    • (2002) Immunity , vol.17 , pp. 703-712
    • Elser, B.1
  • 79
    • 79953033206 scopus 로고    scopus 로고
    • Persistence of cell-mediated immunity three decades after vaccination with the live vaccine strain of Francisella tularensis
    • Eneslatt K, et al. 2011. Persistence of cell-mediated immunity three decades after vaccination with the live vaccine strain of Francisella tularensis. Eur. J. Immunol. 41:974-980.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 974-980
    • Eneslatt, K.1
  • 80
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok VA, et al. 1998. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J. Clin. Invest. 101:890-898.
    • (1998) J. Clin. Invest. , vol.101 , pp. 890-898
    • Fadok, V.A.1
  • 81
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES. 2009. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458:509-513.
    • (2009) Nature , vol.458 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 82
    • 77951263260 scopus 로고    scopus 로고
    • The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
    • Fernandes-Alnemri T, et al. 2010. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat. Immunol. 11:385-393.
    • (2010) Nat. Immunol. , vol.11 , pp. 385-393
    • Fernandes-Alnemri, T.1
  • 83
    • 79951915895 scopus 로고    scopus 로고
    • Novel regulatory functions for Toll-like receptor-activated B cells during intracellular bacterial infection
    • Fillatreau S. 2011. Novel regulatory functions for Toll-like receptor-activated B cells during intracellular bacterial infection. Immunol. Rev. 240:52-71.
    • (2011) Immunol. Rev. , vol.240 , pp. 52-71
    • Fillatreau, S.1
  • 84
    • 16244362671 scopus 로고    scopus 로고
    • Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
    • Fink SL, Cookson BT. 2005. Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infect. Immun. 73:1907-1916.
    • (2005) Infect. Immun. , vol.73 , pp. 1907-1916
    • Fink, S.L.1    Cookson, B.T.2
  • 85
    • 16844363097 scopus 로고    scopus 로고
    • A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
    • Fontenot JD, Rudensky AY. 2005. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat. Immunol. 6:331-337.
    • (2005) Nat. Immunol. , vol.6 , pp. 331-337
    • Fontenot, J.D.1    Rudensky, A.Y.2
  • 86
    • 43049176810 scopus 로고    scopus 로고
    • A conserved and immunodominant lipoprotein of Francisella tularensis is proinflammatory but not essential for virulence
    • Forestal CA, et al. 2008. A conserved and immunodominant lipoprotein of Francisella tularensis is proinflammatory but not essential for virulence. Microb. Pathog. 44:512-523.
    • (2008) Microb. Pathog. , vol.44 , pp. 512-523
    • Forestal, C.A.1
  • 87
    • 34250831089 scopus 로고    scopus 로고
    • Francisella tularensis has a significant extracellular phase in infected mice
    • Forestal CA, et al. 2007. Francisella tularensis has a significant extracellular phase in infected mice. J. Infect. Dis. 196:134-137.
    • (2007) J. Infect. Dis. , vol.196 , pp. 134-137
    • Forestal, C.A.1
  • 88
    • 1642463804 scopus 로고    scopus 로고
    • The lectin-complement pathway - Its role in innate immunity and evolution
    • Fujita T, Matsushita M, Endo Y. 2004. The lectin-complement pathway - its role in innate immunity and evolution. Immunol. Rev. 198:185-202.
    • (2004) Immunol. Rev. , vol.198 , pp. 185-202
    • Fujita, T.1    Matsushita, M.2    Endo, Y.3
  • 89
    • 0035339862 scopus 로고    scopus 로고
    • Salmonella pathogenicity island 2-encoded type III secretion system mediates exclusion of NADPH oxidase assembly from the phagosomal membrane
    • Gallois A, Klein JR, Allen LA, Jones BD, Nauseef WM. 2001. Salmonella pathogenicity island 2-encoded type III secretion system mediates exclusion of NADPH oxidase assembly from the phagosomal membrane. J. Immunol. 166:5741-5748.
    • (2001) J. Immunol. , vol.166 , pp. 5741-5748
    • Gallois, A.1    Klein, J.R.2    Allen, L.A.3    Jones, B.D.4    Nauseef, W.M.5
  • 90
    • 79959484170 scopus 로고    scopus 로고
    • Phagocytic receptors dictate phagosomal escape and intracellular proliferation of Francisella tularensis
    • Geier H, Celli J. 2011. Phagocytic receptors dictate phagosomal escape and intracellular proliferation of Francisella tularensis. Infect. Immun. 79:2204-2214.
    • (2011) Infect. Immun. , vol.79 , pp. 2204-2214
    • Geier, H.1    Celli, J.2
  • 91
    • 33748068465 scopus 로고    scopus 로고
    • Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulence
    • Gil H, et al. 2006. Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulence. Proc. Natl. Acad. Sci. U. S. A. 103:12897-12902.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 12897-12902
    • Gil, H.1
  • 92
    • 0141446069 scopus 로고    scopus 로고
    • An attenuated strain of the facultative intracellular bacterium Francisella tularensis can escape the phagosome of monocytic cells
    • Golovliov I, Baranov V, Krocova Z, Kovarova H, Sjöstedt A. 2003. An attenuated strain of the facultative intracellular bacterium Francisella tularensis can escape the phagosome of monocytic cells. Infect. Immun. 71:5940-5950.
    • (2003) Infect. Immun. , vol.71 , pp. 5940-5950
    • Golovliov, I.1    Baranov, V.2    Krocova, Z.3    Kovarova, H.4    Sjöstedt, A.5
  • 93
    • 77953268611 scopus 로고    scopus 로고
    • Alternative activation of macrophages: Mechanism and functions
    • Gordon S, Martinez FO. 2010. Alternative activation of macrophages: mechanism and functions. Immunity 32:593-604.
    • (2010) Immunity , vol.32 , pp. 593-604
    • Gordon, S.1    Martinez, F.O.2
  • 94
    • 34748816297 scopus 로고    scopus 로고
    • The structure and function of Francisella lipopolysaccharide
    • Gunn JS, Ernst RK. 2007. The structure and function of Francisella lipopolysaccharide. Ann. N. Y. Acad. Sci. 1105:202-218.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1105 , pp. 202-218
    • Gunn, J.S.1    Ernst, R.K.2
  • 95
    • 0028906903 scopus 로고
    • Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system
    • Hagman KE, et al. 1995. Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system. Microbiology 141:611-622.
    • (1995) Microbiology , vol.141 , pp. 611-622
    • Hagman, K.E.1
  • 96
    • 33845496485 scopus 로고    scopus 로고
    • Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors
    • Hajjar AM, et al. 2006. Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infect. Immun. 74:6730-6738.
    • (2006) Infect. Immun. , vol.74 , pp. 6730-6738
    • Hajjar, A.M.1
  • 97
    • 57349174394 scopus 로고    scopus 로고
    • Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112
    • Hall JD, et al. 2008. Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112. Infect. Immun. 76:5843-5852.
    • (2008) Infect. Immun. , vol.76 , pp. 5843-5852
    • Hall, J.D.1
  • 98
    • 44149128160 scopus 로고    scopus 로고
    • Antimicrobial activity of human beta-defensins and induction by Francisella
    • Han S, Bishop BM, van Hoek ML. 2008. Antimicrobial activity of human beta-defensins and induction by Francisella. Biochem. Biophys. Res. Commun. 371:670-674.
    • (2008) Biochem. Biophys. Res. Commun. , vol.371 , pp. 670-674
    • Han, S.1    Bishop, B.M.2    Van Hoek, M.L.3
  • 99
    • 34249044447 scopus 로고    scopus 로고
    • Type I interferon signaling is required for activation of the inflammasome during Francisella infection
    • Henry T, Brotcke A, Weiss DS, Thompson LJ, Monack DM. 2007. Type I interferon signaling is required for activation of the inflammasome during Francisella infection. J. Exp. Med. 204:987-994.
    • (2007) J. Exp. Med. , vol.204 , pp. 987-994
    • Henry, T.1    Brotcke, A.2    Weiss, D.S.3    Thompson, L.J.4    Monack, D.M.5
  • 100
    • 0036645569 scopus 로고    scopus 로고
    • Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosa
    • Hirakata Y, et al. 2002. Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosa. J. Exp. Med. 196:109-118.
    • (2002) J. Exp. Med. , vol.196 , pp. 109-118
    • Hirakata, Y.1
  • 101
    • 63649133278 scopus 로고    scopus 로고
    • AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
    • Hornung V, et al. 2009. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458:514-518.
    • (2009) Nature , vol.458 , pp. 514-518
    • Hornung, V.1
  • 102
    • 0020014215 scopus 로고
    • Phagocytosis of microorganisms
    • Horwitz MA. 1982. Phagocytosis of microorganisms. Rev. Infect. Dis. 4:104-123.
    • (1982) Rev. Infect. Dis. , vol.4 , pp. 104-123
    • Horwitz, M.A.1
  • 103
    • 0021346850 scopus 로고
    • Phagocytosis of the Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: Engulfment within a pseudopod coil
    • Horwitz MA. 1984. Phagocytosis of the Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: engulfment within a pseudopod coil. Cell 36:27-33.
    • (1984) Cell , vol.36 , pp. 27-33
    • Horwitz, M.A.1
  • 104
    • 0038303192 scopus 로고    scopus 로고
    • Modulation of p47PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase
    • Hoyal CR, et al. 2003. Modulation of p47PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase. Proc. Natl. Acad. Sci. U. S. A. 100:5130-5135.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 5130-5135
    • Hoyal, C.R.1
  • 105
    • 39449115193 scopus 로고    scopus 로고
    • Francisella tularensis strain LVS resides in MHC II-positive autophagic vacuoles in macrophages
    • (Praha)
    • Hrstka R, et al. 2007. Francisella tularensis strain LVS resides in MHC II-positive autophagic vacuoles in macrophages. Folia Microbiol. (Praha) 52:631-636.
    • (2007) Folia Microbiol. , vol.52 , pp. 631-636
    • Hrstka, R.1
  • 106
    • 78149489515 scopus 로고    scopus 로고
    • Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis
    • Huang MT, et al. 2010. Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis. J. Immunol. 185:5476-5485.
    • (2010) J. Immunol. , vol.185 , pp. 5476-5485
    • Huang, M.T.1
  • 107
    • 70349943834 scopus 로고    scopus 로고
    • STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
    • Ishikawa H, Ma Z, Barber GN. 2009. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 461:788-792.
    • (2009) Nature , vol.461 , pp. 788-792
    • Ishikawa, H.1    Ma, Z.2    Barber, G.N.3
  • 108
    • 31844433263 scopus 로고    scopus 로고
    • Identification of hBD-3 in respiratory tract and serum: The increase in pneumonia
    • Ishimoto H, et al. 2006. Identification of hBD-3 in respiratory tract and serum: the increase in pneumonia. Eur. Respir. J. 27:253-260.
    • (2006) Eur. Respir. J. , vol.27 , pp. 253-260
    • Ishimoto, H.1
  • 110
    • 77957736080 scopus 로고    scopus 로고
    • A Francisella tularensis live vaccine strain (LVS) mutant with a deletion in capB, encoding a putative capsular biosynthesis protein, is significantly more attenuated than LVS yet induces potent protective immunity in mice against F. tularensis challenge
    • Jia Q, et al. 2010. A Francisella tularensis live vaccine strain (LVS) mutant with a deletion in capB, encoding a putative capsular biosynthesis protein, is significantly more attenuated than LVS yet induces potent protective immunity in mice against F. tularensis challenge. Infect. Immun. 78:4341-4355.
    • (2010) Infect. Immun. , vol.78 , pp. 4341-4355
    • Jia, Q.1
  • 111
    • 79959221587 scopus 로고    scopus 로고
    • TLR2 signaling contributes to rapid inflammasome activation during F. novicida infection
    • Jones CL, Weiss DS. 2011. TLR2 signaling contributes to rapid inflammasome activation during F. novicida infection. PLoS One 6:e20609.
    • (2011) PLoS One , vol.6
    • Jones, C.L.1    Weiss, D.S.2
  • 112
    • 77953116282 scopus 로고    scopus 로고
    • Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
    • Jones JW, et al. 2010. Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proc. Natl. Acad. Sci. U. S. A. 107:9771-9776.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 9771-9776
    • Jones, J.W.1
  • 113
    • 25844508945 scopus 로고    scopus 로고
    • The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis
    • Kang PB, et al. 2005. The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis. J. Exp. Med. 202:987-999.
    • (2005) J. Exp. Med. , vol.202 , pp. 987-999
    • Kang, P.B.1
  • 114
    • 40349116308 scopus 로고    scopus 로고
    • A Francisella mutant in lipid A carbohydrate modification elicits protective immunity
    • Kanistanon D, et al. 2008. A Francisella mutant in lipid A carbohydrate modification elicits protective immunity. PLoS Pathog. 4:e24.
    • (2008) PLoS Pathog. , vol.4
    • Kanistanon, D.1
  • 115
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • Kawai T, Akira S. 2010. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11:373-384.
    • (2010) Nat. Immunol. , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 116
    • 0037989109 scopus 로고    scopus 로고
    • Francisella novicida LPS has greater immunobiological activity in mice than F. tularensis LPS, and contributes to F. novicida murine pathogenesis
    • Kieffer TL, Cowley S, Nano FE, Elkins KL. 2003. Francisella novicida LPS has greater immunobiological activity in mice than F. tularensis LPS, and contributes to F. novicida murine pathogenesis. Microbes Infect. 5:397-403.
    • (2003) Microbes Infect. , vol.5 , pp. 397-403
    • Kieffer, T.L.1    Cowley, S.2    Nano, F.E.3    Elkins, K.L.4
  • 118
    • 80053379974 scopus 로고    scopus 로고
    • Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
    • Kofoed EM, Vance RE. 2011. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477:592-595.
    • (2011) Nature , vol.477 , pp. 592-595
    • Kofoed, E.M.1    Vance, R.E.2
  • 119
    • 47249113377 scopus 로고    scopus 로고
    • Interaction of B cells with intracellular pathogen Francisella tularensis
    • Krocova Z, et al. 2008. Interaction of B cells with intracellular pathogen Francisella tularensis. Microb. Pathog. 45:79-85.
    • (2008) Microb. Pathog. , vol.45 , pp. 79-85
    • Krocova, Z.1
  • 120
    • 0034972441 scopus 로고    scopus 로고
    • Francisella tularensis induces cytopathogenicity and apoptosis in murine macrophages via a mechanism that requires intracellular bacterial multiplication
    • Lai XH, Golovliov I, Sjostedt A. 2001. Francisella tularensis induces cytopathogenicity and apoptosis in murine macrophages via a mechanism that requires intracellular bacterial multiplication. Infect. Immun. 69:4691-4694.
    • (2001) Infect. Immun. , vol.69 , pp. 4691-4694
    • Lai, X.H.1    Golovliov, I.2    Sjostedt, A.3
  • 121
    • 67149121074 scopus 로고    scopus 로고
    • TLR4/MyD88/PI3K interactions regulate TLR4 signaling
    • Laird MH, et al. 2009. TLR4/MyD88/PI3K interactions regulate TLR4 signaling. J. Leukoc. Biol. 85:966-977.
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 966-977
    • Laird, M.H.1
  • 122
    • 13944273799 scopus 로고    scopus 로고
    • The complete genome sequence of Francisella tularensis, the causative agent of tularemia
    • Larsson P, et al. 2005. The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nat. Genet. 37:153-159.
    • (2005) Nat. Genet. , vol.37 , pp. 153-159
    • Larsson, P.1
  • 123
    • 84859743402 scopus 로고    scopus 로고
    • Francisella tularensis uses cholesterol and clathrin-based endocytic mechanisms to invade hepatocytes
    • Law HT, et al. 2011. Francisella tularensis uses cholesterol and clathrin-based endocytic mechanisms to invade hepatocytes. Sci. Rep. 1:192.
    • (2011) Sci. Rep. , vol.1 , pp. 192
    • Law, H.T.1
  • 124
    • 0034711266 scopus 로고    scopus 로고
    • LcrV, a substrate for Yersinia enterocolitica type III secretion, is required for toxin targeting into the cytosol of HeLa cells
    • Lee VT, Tam C, Schneewind O. 2000. LcrV, a substrate for Yersinia enterocolitica type III secretion, is required for toxin targeting into the cytosol of HeLa cells. J. Biol. Chem. 275:36869-36875.
    • (2000) J. Biol. Chem. , vol.275 , pp. 36869-36875
    • Lee, V.T.1    Tam, C.2    Schneewind, O.3
  • 126
    • 0026571327 scopus 로고
    • In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodies
    • Leiby DA, Fortier AH, Crawford RM, Schreiber RD, Nacy CA. 1992. In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodies. Infect. Immun. 60:84-89.
    • (1992) Infect. Immun. , vol.60 , pp. 84-89
    • Leiby, D.A.1    Fortier, A.H.2    Crawford, R.M.3    Schreiber, R.D.4    Nacy, C.A.5
  • 127
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine B, Mizushima N, Virgin HW. 2011. Autophagy in immunity and inflammation. Nature 469:323-335.
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 128
    • 33751532631 scopus 로고    scopus 로고
    • Innate immune response to Francisella tularensis is mediated by TLR2 and caspase-1 activation
    • Li H, Nookala S, Bina XR, Bina JE, Re F. 2006. Innate immune response to Francisella tularensis is mediated by TLR2 and caspase-1 activation. J. Leukoc. Biol. 80:766-773.
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 766-773
    • Li, H.1    Nookala, S.2    Bina, X.R.3    Bina, J.E.4    Re, F.5
  • 129
    • 34948902287 scopus 로고    scopus 로고
    • Attenuation and protective efficacy of an O-antigen-deficient mutant of Francisella tularensis LVS
    • Li J, et al. 2007. Attenuation and protective efficacy of an O-antigen-deficient mutant of Francisella tularensis LVS. Microbiology 153:3141-3153.
    • (2007) Microbiology , vol.153 , pp. 3141-3153
    • Li, J.1
  • 130
    • 79251510219 scopus 로고    scopus 로고
    • Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages
    • Lindemann SR, et al. 2011. Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages. Infect. Immun. 79:581-594.
    • (2011) Infect. Immun. , vol.79 , pp. 581-594
    • Lindemann, S.R.1
  • 131
    • 6344269866 scopus 로고    scopus 로고
    • Factors affecting the escape of Francisella tularensis from the phagolysosome
    • Lindgren H, et al. 2004. Factors affecting the escape of Francisella tularensis from the phagolysosome. J. Med. Microbiol. 53:953-958.
    • (2004) J. Med. Microbiol. , vol.53 , pp. 953-958
    • Lindgren, H.1
  • 132
    • 70349420956 scopus 로고    scopus 로고
    • The 58-kilodalton major virulence factor of Francisella tularensis is required for efficient utilization of iron
    • Lindgren H, et al. 2009. The 58-kilodalton major virulence factor of Francisella tularensis is required for efficient utilization of iron. Infect. Immun. 77:4429-4436.
    • (2009) Infect. Immun. , vol.77 , pp. 4429-4436
    • Lindgren, H.1
  • 133
    • 79952286485 scopus 로고    scopus 로고
    • 2-induced killing
    • 2-induced killing. Infect. Immun. 79:1218-1224.
    • (2011) Infect. Immun. , vol.79 , pp. 1218-1224
    • Lindgren, H.1
  • 134
    • 33847716729 scopus 로고    scopus 로고
    • Resistance of Francisella tularensis strains against reactive nitrogen and oxygen species with special reference to the role of KatG
    • Lindgren H, et al. 2007. Resistance of Francisella tularensis strains against reactive nitrogen and oxygen species with special reference to the role of KatG. Infect. Immun. 75:1303-1309.
    • (2007) Infect. Immun. , vol.75 , pp. 1303-1309
    • Lindgren, H.1
  • 135
    • 80052479082 scopus 로고    scopus 로고
    • Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence
    • Llewellyn AC, Jones CL, Napier BA, Bina JE, Weiss DS. 2011. Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence. PLoS One 6:e24201.
    • (2011) PLoS One , vol.6
    • Llewellyn, A.C.1    Jones, C.L.2    Napier, B.A.3    Bina, J.E.4    Weiss, D.S.5
  • 136
    • 0027514532 scopus 로고
    • Detection of Francisella tularensis in blood by polymerase chain reaction
    • Long GW, et al. 1993. Detection of Francisella tularensis in blood by polymerase chain reaction. J. Clin. Microbiol. 31:152-154.
    • (1993) J. Clin. Microbiol. , vol.31 , pp. 152-154
    • Long, G.W.1
  • 137
    • 0020596647 scopus 로고
    • The binding of human plasminogen to fibrin and fibrinogen
    • Lucas MA, Fretto LJ, McKee PA. 1983. The binding of human plasminogen to fibrin and fibrinogen. J. Biol. Chem. 258:4249-4256.
    • (1983) J. Biol. Chem. , vol.258 , pp. 4249-4256
    • Lucas, M.A.1    Fretto, L.J.2    McKee, P.A.3
  • 138
    • 0029876826 scopus 로고    scopus 로고
    • The immune response against Francisella tularensis live vaccine strain in Lps(n) and Lps(d) mice
    • Macela A, et al. 1996. The immune response against Francisella tularensis live vaccine strain in Lps(n) and Lps(d) mice. FEMS Immunol. Med. Microbiol. 13:235-238.
    • (1996) FEMS Immunol. Med. Microbiol. , vol.13 , pp. 235-238
    • Macela, A.1
  • 139
    • 0036378101 scopus 로고    scopus 로고
    • Immature, but not inactive: The tolerogenic function of immature dendritic cells
    • Mahnke K, Schmitt E, Bonifaz L, Enk AH, Jonuleit H. 2002. Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol. Cell Biol. 80:477-483.
    • (2002) Immunol. Cell Biol. , vol.80 , pp. 477-483
    • Mahnke, K.1    Schmitt, E.2    Bonifaz, L.3    Enk, A.H.4    Jonuleit, H.5
  • 140
    • 35648989527 scopus 로고    scopus 로고
    • Identification of Francisella tularensis Himar1-based transposon mutants defective for replication in macrophages
    • Maier TM, et al. 2007. Identification of Francisella tularensis Himar1-based transposon mutants defective for replication in macrophages. Infect. Immun. 75:5376-5389.
    • (2007) Infect. Immun. , vol.75 , pp. 5376-5389
    • Maier, T.M.1
  • 141
    • 26844452231 scopus 로고    scopus 로고
    • Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis
    • Mariathasan S, Weiss DS, Dixit VM, Monack DM. 2005. Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J. Exp. Med. 202:1043-1049.
    • (2005) J. Exp. Med. , vol.202 , pp. 1043-1049
    • Mariathasan, S.1    Weiss, D.S.2    Dixit, V.M.3    Monack, D.M.4
  • 142
    • 32944470765 scopus 로고    scopus 로고
    • Cryopyrin activates the inflammasome in response to toxins and ATP
    • Mariathasan S, et al. 2006. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440:228-232.
    • (2006) Nature , vol.440 , pp. 228-232
    • Mariathasan, S.1
  • 143
    • 0035954430 scopus 로고    scopus 로고
    • Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis
    • Marshall JG, et al. 2001. Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis. J. Cell Biol. 153:1369-1380.
    • (2001) J. Cell Biol. , vol.153 , pp. 1369-1380
    • Marshall, J.G.1
  • 145
    • 33845383728 scopus 로고    scopus 로고
    • Francisella tularensis LVS evades killing by human neutrophils via inhibition of the respiratory burst and phagosome escape
    • McCaffrey RL, Allen LA. 2006. Francisella tularensis LVS evades killing by human neutrophils via inhibition of the respiratory burst and phagosome escape. J. Leukoc. Biol. 80:1224-1230.
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 1224-1230
    • McCaffrey, R.L.1    Allen, L.A.2
  • 146
    • 77957887794 scopus 로고    scopus 로고
    • Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis
    • McCaffrey RL, et al. 2010. Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis. J. Leukoc. Biol. 88:791-805.
    • (2010) J. Leukoc. Biol. , vol.88 , pp. 791-805
    • McCaffrey, R.L.1
  • 147
    • 84862558237 scopus 로고
    • Some features of the squirrel plague problem
    • McCoy GW. 1911. Some features of the squirrel plague problem. Cal. State J. Med. 9:105-109.
    • (1911) Cal. State J. Med. , vol.9 , pp. 105-109
    • McCoy, G.W.1
  • 148
    • 78650642949 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain
    • Medina EA, Morris IR, Berton MT. 2010. Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain. J. Immunol. 185:7562-7572.
    • (2010) J. Immunol. , vol.185 , pp. 7562-7572
    • Medina, E.A.1    Morris, I.R.2    Berton, M.T.3
  • 149
    • 84862569199 scopus 로고    scopus 로고
    • Francisella tularensis metabolism and its relation to virulence
    • Meibom KL, Charbit A. 2010. Francisella tularensis metabolism and its relation to virulence. Front. Microbiol. 1:140.
    • (2010) Front. Microbiol. , vol.1 , pp. 140
    • Meibom, K.L.1    Charbit, A.2
  • 150
    • 77956257884 scopus 로고    scopus 로고
    • Francisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine production
    • Melillo AA, Bakshi CS, Melendez JA. 2010. Francisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine production. J. Biol. Chem. 285:27553-27560.
    • (2010) J. Biol. Chem. , vol.285 , pp. 27553-27560
    • Melillo, A.A.1    Bakshi, C.S.2    Melendez, J.A.3
  • 151
    • 70350449301 scopus 로고    scopus 로고
    • Identification of Francisella tularensis live vaccine strain CuZn superoxide dismutase as critical for resistance to extracellularly generated reactive oxygen species
    • Melillo AA, et al. 2009. Identification of Francisella tularensis live vaccine strain CuZn superoxide dismutase as critical for resistance to extracellularly generated reactive oxygen species. J. Bacteriol. 191:6447-6456.
    • (2009) J. Bacteriol. , vol.191 , pp. 6447-6456
    • Melillo, A.A.1
  • 152
    • 77649241461 scopus 로고    scopus 로고
    • Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
    • Miao EA, et al. 2010. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc. Natl. Acad. Sci. U. S. A. 107:3076-3080.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 3076-3080
    • Miao, E.A.1
  • 153
    • 78049496555 scopus 로고    scopus 로고
    • Deletion of the Bacillus anthracis capB homologue in Francisella tularensis subspecies tularensis generates an attenuated strain that protects mice against virulent tularaemia
    • Michell S, et al. 2010. Deletion of the Bacillus anthracis capB homologue in Francisella tularensis subspecies tularensis generates an attenuated strain that protects mice against virulent tularaemia. J. Med. Microbiol. 59:1275-1284.
    • (2010) J. Med. Microbiol. , vol.59 , pp. 1275-1284
    • Michell, S.1
  • 154
    • 34548739613 scopus 로고    scopus 로고
    • Siderophore-based iron acquisition and pathogen control
    • Miethke M, Marahiel MA. 2007. Siderophore-based iron acquisition and pathogen control. Microbiol. Mol. Biol. Rev. 71:413-451.
    • (2007) Microbiol. Mol. Biol. Rev. , vol.71 , pp. 413-451
    • Miethke, M.1    Marahiel, M.A.2
  • 155
    • 77954479994 scopus 로고    scopus 로고
    • Francisella acid phosphatases inactivate the NADPH oxidase in human phagocytes
    • Mohapatra NP, et al. 2010. Francisella acid phosphatases inactivate the NADPH oxidase in human phagocytes. J. Immunol. 184:5141-5150.
    • (2010) J. Immunol. , vol.184 , pp. 5141-5150
    • Mohapatra, N.P.1
  • 156
    • 48849083688 scopus 로고    scopus 로고
    • Combined deletion of four Francisella novicida acid phosphatases attenuates virulence and macrophage vacuolar escape
    • Mohapatra NP, et al. 2008. Combined deletion of four Francisella novicida acid phosphatases attenuates virulence and macrophage vacuolar escape. Infect. Immun. 76:3690-3699.
    • (2008) Infect. Immun. , vol.76 , pp. 3690-3699
    • Mohapatra, N.P.1
  • 158
    • 0033215094 scopus 로고    scopus 로고
    • Regulation of iron metabolism in murine J774 macrophages: Role of nitric oxide-dependent and -independent pathways following activation with gamma interferon and lipopolysaccharide
    • Mulero V, Brock JH. 1999. Regulation of iron metabolism in murine J774 macrophages: role of nitric oxide-dependent and -independent pathways following activation with gamma interferon and lipopolysaccharide. Blood 94:2383-2389.
    • (1999) Blood , vol.94 , pp. 2383-2389
    • Mulero, V.1    Brock, J.H.2
  • 160
    • 79953671494 scopus 로고    scopus 로고
    • Evasion of IFN-γ signaling by Francisella novicida is dependent upon Francisella outer membrane protein C
    • 31 March
    • Nallaparaju KC, et al. 31 March 2011. Evasion of IFN-γ signaling by Francisella novicida is dependent upon Francisella outer membrane protein C. PLoS One 6:e18201.
    • (2011) PLoS One , vol.6
    • Nallaparaju, K.C.1
  • 161
    • 34748882473 scopus 로고    scopus 로고
    • The Francisella pathogenicity island
    • Nano FE, Schmerk C. 2007. The Francisella pathogenicity island. Ann. N. Y. Acad. Sci. 1105:122-137.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1105 , pp. 122-137
    • Nano, F.E.1    Schmerk, C.2
  • 162
    • 8644255770 scopus 로고    scopus 로고
    • Assembly of the phagocyte NADPH oxidase. Histochem
    • Nauseef WM. 2004. Assembly of the phagocyte NADPH oxidase. Histochem. Cell Biol. 122:277-291.
    • (2004) Cell Biol. , vol.122 , pp. 277-291
    • Nauseef, W.M.1
  • 163
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E, et al. 2004. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306:2090-2093.
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1
  • 164
    • 78650219406 scopus 로고    scopus 로고
    • Signaling via the MyD88 adaptor protein in B cells suppresses protective immunity during Salmonella typhimurium infection
    • Neves P, et al. 2010. Signaling via the MyD88 adaptor protein in B cells suppresses protective immunity during Salmonella typhimurium infection. Immunity 33:777-790.
    • (2010) Immunity , vol.33 , pp. 777-790
    • Neves, P.1
  • 165
    • 0032481383 scopus 로고    scopus 로고
    • IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: Evidence for Stat3-dependent and -independent pathways
    • O'Farrell AM, Liu Y, Moore KW, Mui AL. 1998. IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways. EMBO J. 17:1006-1018.
    • (1998) EMBO J. , vol.17 , pp. 1006-1018
    • O'Farrell, A.M.1    Liu, Y.2    Moore, K.W.3    Mui, A.L.4
  • 166
    • 77949543589 scopus 로고    scopus 로고
    • Modulation of iron homeostasis in macrophages by bacterial intracellular pathogens
    • Pan X, Tamilselvam B, Hansen EJ, Daefler S. 2010. Modulation of iron homeostasis in macrophages by bacterial intracellular pathogens. BMC Microbiol. 10:64.
    • (2010) BMC Microbiol. , vol.10 , pp. 64
    • Pan, X.1    Tamilselvam, B.2    Hansen, E.J.3    Daefler, S.4
  • 167
    • 44749083060 scopus 로고    scopus 로고
    • Francisella gains a survival advantage within mononuclear phagocytes by suppressing the host IFNgamma response
    • Parsa KV, et al. 2008. Francisella gains a survival advantage within mononuclear phagocytes by suppressing the host IFNgamma response. Mol. Immunol. 45:3428-3437.
    • (2008) Mol. Immunol. , vol.45 , pp. 3428-3437
    • Parsa, K.V.1
  • 168
    • 33746592575 scopus 로고    scopus 로고
    • Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP
    • Parsa KV, et al. 2006. Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP. PLoS Pathog. 2:e71.
    • (2006) PLoS Pathog. , vol.2
    • Parsa, K.V.1
  • 169
    • 0028028122 scopus 로고
    • Shigella flexneri: Genetics of entry and intercellular dissemination in epithelial cells
    • Parsot C. 1994. Shigella flexneri: genetics of entry and intercellular dissemination in epithelial cells. Curr. Top. Microbiol. Immunol. 192:217-241.
    • (1994) Curr. Top. Microbiol. Immunol. , vol.192 , pp. 217-241
    • Parsot, C.1
  • 170
    • 33746596554 scopus 로고    scopus 로고
    • Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain
    • Pechous R, et al. 2006. Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain. Infect. Immun. 74:4452-4461.
    • (2006) Infect. Immun. , vol.74 , pp. 4452-4461
    • Pechous, R.1
  • 172
    • 80052813504 scopus 로고    scopus 로고
    • Elevated AIM2-mediated pyroptosis triggered by hypercytotoxic Francisella mutant strains is attributed to increased intracellular bacteriolysis
    • Peng K, Broz P, Jones J, Joubert LM, Monack D. 2011. Elevated AIM2-mediated pyroptosis triggered by hypercytotoxic Francisella mutant strains is attributed to increased intracellular bacteriolysis. Cell Microbiol. 13:1586-1600.
    • (2011) Cell Microbiol. , vol.13 , pp. 1586-1600
    • Peng, K.1    Broz, P.2    Jones, J.3    Joubert, L.M.4    Monack, D.5
  • 173
    • 77952718220 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase 1 is a lung-specific innate immune defense mechanism that inhibits growth of Francisella tularensis tryptophan auxotrophs
    • Peng K, Monack DM. 2010. Indoleamine 2,3-dioxygenase 1 is a lung-specific innate immune defense mechanism that inhibits growth of Francisella tularensis tryptophan auxotrophs. Infect. Immun. 78:2723-2733.
    • (2010) Infect. Immun. , vol.78 , pp. 2723-2733
    • Peng, K.1    Monack, D.M.2
  • 174
    • 80052358761 scopus 로고    scopus 로고
    • Development of tolerogenic dendritic cells and regulatory T cells favors exponential bacterial growth and survival during early respiratory tularemia
    • Periasamy S, et al. 2011. Development of tolerogenic dendritic cells and regulatory T cells favors exponential bacterial growth and survival during early respiratory tularemia. J. Leukoc. Biol. 90:493-507.
    • (2011) J. Leukoc. Biol. , vol.90 , pp. 493-507
    • Periasamy, S.1
  • 175
    • 77955655337 scopus 로고    scopus 로고
    • Nod-like receptors: Sentinels at host membranes
    • Philpott DJ, Girardin SE. 2010. Nod-like receptors: sentinels at host membranes. Curr. Opin. Immunol. 22:428-434.
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 428-434
    • Philpott, D.J.1    Girardin, S.E.2
  • 176
    • 0025744448 scopus 로고
    • A new view of prostaglandin e regulation of the immune response
    • Phipps RP, Stein SH, Roper RL. 1991. A new view of prostaglandin E regulation of the immune response. Immunol. Today 12:349-352.
    • (1991) Immunol. Today , vol.12 , pp. 349-352
    • Phipps, R.P.1    Stein, S.H.2    Roper, R.L.3
  • 177
    • 33745762939 scopus 로고    scopus 로고
    • Uptake of serum-opsonized Francisella tularensis by macrophages can be mediated by class A scavenger receptors
    • Pierini LM. 2006. Uptake of serum-opsonized Francisella tularensis by macrophages can be mediated by class A scavenger receptors. Cell. Microbiol. 8:1361-1370.
    • (2006) Cell. Microbiol. , vol.8 , pp. 1361-1370
    • Pierini, L.M.1
  • 178
    • 33646897295 scopus 로고    scopus 로고
    • Identification of Burkholderia pseudomallei genes required for the intracellular life cycle and in vivo virulence
    • Pilatz S, et al. 2006. Identification of Burkholderia pseudomallei genes required for the intracellular life cycle and in vivo virulence. Infect. Immun. 74:3576-3586.
    • (2006) Infect. Immun. , vol.74 , pp. 3576-3586
    • Pilatz, S.1
  • 179
    • 77349085520 scopus 로고    scopus 로고
    • A tolC mutant of Francisella tularensis is hypercytotoxic compared to the wild type and elicits increased proinflammatory responses from host cells
    • Platz GJ, et al. 2010. A tolC mutant of Francisella tularensis is hypercytotoxic compared to the wild type and elicits increased proinflammatory responses from host cells. Infect. Immun. 78:1022-1031.
    • (2010) Infect. Immun. , vol.78 , pp. 1022-1031
    • Platz, G.J.1
  • 180
    • 0027494050 scopus 로고
    • Multiple antibiotic resistance in Pseudomonas aeruginosa: Evidence for involvement of an efflux operon
    • Poole K, Krebes K, McNally C, Neshat S. 1993. Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon. J. Bacteriol. 175:7363-7372.
    • (1993) J. Bacteriol. , vol.175 , pp. 7363-7372
    • Poole, K.1    Krebes, K.2    McNally, C.3    Neshat, S.4
  • 181
    • 66349133664 scopus 로고    scopus 로고
    • Discovery of new biosynthetic pathways: The lipid A story
    • Raetz CR, et al. 2009. Discovery of new biosynthetic pathways: the lipid A story. J. Lipid Res. 50(Suppl.):S103-S108.
    • (2009) J. Lipid Res. , vol.50 , Issue.SUPPL.
    • Raetz, C.R.1
  • 182
    • 70949108107 scopus 로고    scopus 로고
    • Akt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway
    • Rajaram MV, et al. 2009. Akt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway. PLoS One 4:e7919.
    • (2009) PLoS One , vol.4
    • Rajaram, M.V.1
  • 183
    • 48149110160 scopus 로고    scopus 로고
    • fslE is necessary for siderophore-mediated iron acquisition in Francisella tularensis Schu S4
    • Ramakrishnan G, Meeker A, Dragulev B. 2008. fslE is necessary for siderophore-mediated iron acquisition in Francisella tularensis Schu S4. J. Bacteriol. 190:5353-5361.
    • (2008) J. Bacteriol. , vol.190 , pp. 5353-5361
    • Ramakrishnan, G.1    Meeker, A.2    Dragulev, B.3
  • 184
    • 77951269392 scopus 로고    scopus 로고
    • The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
    • Rathinam VA, et al. 2010. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat. Immunol. 11:395-402.
    • (2010) Nat. Immunol. , vol.11 , pp. 395-402
    • Rathinam, V.A.1
  • 185
    • 64749104915 scopus 로고    scopus 로고
    • Life on the inside: The intracellular lifestyle of cytosolic bacteria
    • Ray K, Marteyn B, Sansonetti PJ, Tang CM. 2009. Life on the inside: the intracellular lifestyle of cytosolic bacteria. Nat. Rev. Microbiol. 7:333-340.
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 333-340
    • Ray, K.1    Marteyn, B.2    Sansonetti, P.J.3    Tang, C.M.4
  • 186
    • 0032006692 scopus 로고    scopus 로고
    • Nitric oxidemediated induction of ferritin synthesis in J774 macrophages by inflammatory cytokines: Role of selective iron regulatory protein-2 downregulation
    • Recalcati S, Taramelli D, Conte D, Cairo G. 1998. Nitric oxidemediated induction of ferritin synthesis in J774 macrophages by inflammatory cytokines: role of selective iron regulatory protein-2 downregulation. Blood 91:1059-1066.
    • (1998) Blood , vol.91 , pp. 1059-1066
    • Recalcati, S.1    Taramelli, D.2    Conte, D.3    Cairo, G.4
  • 187
    • 15844404772 scopus 로고    scopus 로고
    • Characterization and sequencing of a respiratory burst-inhibiting acid phosphatase from Francisella tularensis
    • Reilly TJ, Baron GS, Nano FE, Kuhlenschmidt MS. 1996. Characterization and sequencing of a respiratory burst-inhibiting acid phosphatase from Francisella tularensis. J. Biol. Chem. 271:10973-10983.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10973-10983
    • Reilly, T.J.1    Baron, G.S.2    Nano, F.E.3    Kuhlenschmidt, M.S.4
  • 188
    • 60749104535 scopus 로고    scopus 로고
    • HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
    • Roberts TL, et al. 2009. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science 323:1057-1060.
    • (2009) Science , vol.323 , pp. 1057-1060
    • Roberts, T.L.1
  • 189
    • 39549114621 scopus 로고    scopus 로고
    • Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains
    • Rohmer L, et al. 2007. Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome Biol. 8:R102.
    • (2007) Genome Biol. , vol.8
    • Rohmer, L.1
  • 190
    • 58049217443 scopus 로고    scopus 로고
    • Francisella inhibits STAT1-mediated signaling in macrophages and prevents activation of antigen-specific T cells
    • Roth KM, Gunn JS, Lafuse W, Satoskar AR. 2009. Francisella inhibits STAT1-mediated signaling in macrophages and prevents activation of antigen-specific T cells. Int. Immunol. 21:19-28.
    • (2009) Int. Immunol. , vol.21 , pp. 19-28
    • Roth, K.M.1    Gunn, J.S.2    Lafuse, W.3    Satoskar, A.R.4
  • 191
    • 26844548098 scopus 로고    scopus 로고
    • The role of the complement system in innate immunity
    • Rus H, Cudrici C, Niculescu F. 2005. The role of the complement system in innate immunity. Immunol. Res. 33:103-112.
    • (2005) Immunol. Res. , vol.33 , pp. 103-112
    • Rus, H.1    Cudrici, C.2    Niculescu, F.3
  • 192
    • 80052326950 scopus 로고    scopus 로고
    • A Francisella tularensis locus required for spermine responsiveness is necessary for virulence
    • Russo BC, et al. 2011. A Francisella tularensis locus required for spermine responsiveness is necessary for virulence. Infect. Immun. 79:3665-3676.
    • (2011) Infect. Immun. , vol.79 , pp. 3665-3676
    • Russo, B.C.1
  • 193
    • 0023903237 scopus 로고
    • A capsule-deficient mutant of Francisella tularensis LVS exhibits enhanced sensitivity to killing by serum but diminished sensitivity to killing by polymorphonuclear leukocytes
    • Sandstrom G, Lofgren S, Tarnvik A. 1988. A capsule-deficient mutant of Francisella tularensis LVS exhibits enhanced sensitivity to killing by serum but diminished sensitivity to killing by polymorphonuclear leukocytes. Infect. Immun. 56:1194-1202.
    • (1988) Infect. Immun. , vol.56 , pp. 1194-1202
    • Sandstrom, G.1    Lofgren, S.2    Tarnvik, A.3
  • 194
    • 0022630209 scopus 로고
    • Multiplication of Shigella flexneri within HeLa cells: Lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis
    • Sansonetti PJ, Ryter A, Clerc P, Maurelli AT, Mounier J. 1986. Multiplication of Shigella flexneri within HeLa cells: lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis. Infect. Immun. 51:461-469.
    • (1986) Infect. Immun. , vol.51 , pp. 461-469
    • Sansonetti, P.J.1    Ryter, A.2    Clerc, P.3    Maurelli, A.T.4    Mounier, J.5
  • 195
    • 46249110662 scopus 로고    scopus 로고
    • Acquisition of the vacuolar ATPase proton pump and phagosome acidification are essential for escape of Francisella tularensis into the macrophage cytosol
    • Santic M, Asare R, Skrobonja I, Jones S, Abu Kwaik Y. 2008. Acquisition of the vacuolar ATPase proton pump and phagosome acidification are essential for escape of Francisella tularensis into the macrophage cytosol. Infect. Immun. 76:2671-2677.
    • (2008) Infect. Immun. , vol.76 , pp. 2671-2677
    • Santic, M.1    Asare, R.2    Skrobonja, I.3    Jones, S.4    Abu Kwaik, Y.5
  • 196
    • 21344436430 scopus 로고    scopus 로고
    • Modulation of biogenesis of the Francisella tularensis subsp. novicida-containing phagosome in quiescent human macrophages and its maturation into a phagolysosome upon activation by IFN-gamma
    • Santic M, Molmeret M, Abu Kwaik Y. 2005. Modulation of biogenesis of the Francisella tularensis subsp. novicida-containing phagosome in quiescent human macrophages and its maturation into a phagolysosome upon activation by IFN-gamma. Cell. Microbiol. 7:957-967.
    • (2005) Cell. Microbiol. , vol.7 , pp. 957-967
    • Santic, M.1    Molmeret, M.2    Abu Kwaik, Y.3
  • 197
    • 21344468870 scopus 로고    scopus 로고
    • The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm
    • Santic M, Molmeret M, Klose KE, Jones S, Kwaik YA. 2005. The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm. Cell. Microbiol. 7:969-979.
    • (2005) Cell. Microbiol. , vol.7 , pp. 969-979
    • Santic, M.1    Molmeret, M.2    Klose, K.E.3    Jones, S.4    Kwaik, Y.A.5
  • 198
    • 0024419644 scopus 로고
    • Functional organization and nucleotide sequence of virulence region-2 on the large virulence plasmid in Shigella flexneri 2a
    • Sasakawa C, et al. 1989. Functional organization and nucleotide sequence of virulence region-2 on the large virulence plasmid in Shigella flexneri 2a. Mol. Microbiol. 3:1191-1201.
    • (1989) Mol. Microbiol. , vol.3 , pp. 1191-1201
    • Sasakawa, C.1
  • 199
    • 0036528903 scopus 로고    scopus 로고
    • Increased levels of antimicrobial peptides in tracheal aspirates of newborn infants during infection
    • Schaller-Bals S, Schulze A, Bals R. 2002. Increased levels of antimicrobial peptides in tracheal aspirates of newborn infants during infection. Am. J. Respir. Crit. Care Med. 165:992-995.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , pp. 992-995
    • Schaller-Bals, S.1    Schulze, A.2    Bals, R.3
  • 200
    • 0025216480 scopus 로고
    • Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3
    • Schlesinger LS, Bellinger-Kawahara CG, Payne NR, Horwitz MA. 1990. Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3. J. Immunol. 144:2771-2780.
    • (1990) J. Immunol. , vol.144 , pp. 2771-2780
    • Schlesinger, L.S.1    Bellinger-Kawahara, C.G.2    Payne, N.R.3    Horwitz, M.A.4
  • 201
    • 0025278804 scopus 로고
    • Phagocytosis of leprosy bacilli is mediated by complement receptors CR1 and CR3 on human monocytes and complement component C3 in serum
    • Schlesinger LS, Horwitz MA. 1990. Phagocytosis of leprosy bacilli is mediated by complement receptors CR1 and CR3 on human monocytes and complement component C3 in serum. J. Clin. Invest. 85:1304-1314.
    • (1990) J. Clin. Invest. , vol.85 , pp. 1304-1314
    • Schlesinger, L.S.1    Horwitz, M.A.2
  • 202
    • 0842266786 scopus 로고    scopus 로고
    • Interferon-gamma: An overview of signals, mechanisms and functions
    • Schroder K, Hertzog PJ, Ravasi T, Hume DA. 2004. Interferon-gamma: an overview of signals, mechanisms and functions. J. Leukoc. Biol. 75:163-189.
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 163-189
    • Schroder, K.1    Hertzog, P.J.2    Ravasi, T.3    Hume, D.A.4
  • 203
    • 33751501420 scopus 로고    scopus 로고
    • Differential infection of mononuclear phagocytes by Francisella tularensis: Role of the macrophage mannose receptor
    • Schulert GS, Allen LA. 2006. Differential infection of mononuclear phagocytes by Francisella tularensis: role of the macrophage mannose receptor. J. Leukoc. Biol. 80:563-571.
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 563-571
    • Schulert, G.S.1    Allen, L.A.2
  • 204
    • 63149103523 scopus 로고    scopus 로고
    • Francisella tularensis genes required for inhibition of the neutrophil respiratory burst and intramacrophage growth identified by
    • random transposon mutagenesis of strain LVS.
    • Schulert GS, et al. 2009. Francisella tularensis genes required for inhibition of the neutrophil respiratory burst and intramacrophage growth identified by random transposon mutagenesis of strain LVS. Infect. Immun. 77:1324-1336.
    • (2009) Infect. Immun. , vol.77 , pp. 1324-1336
    • Schulert, G.S.1
  • 205
    • 34248379117 scopus 로고    scopus 로고
    • A defined O-antigen polysaccharide mutant of Francisella tularensis live vaccine strain has attenuated virulence while retaining its protective capacity
    • Sebastian S, et al. 2007. A defined O-antigen polysaccharide mutant of Francisella tularensis live vaccine strain has attenuated virulence while retaining its protective capacity. Infect. Immun. 75:2591-2602.
    • (2007) Infect. Immun. , vol.75 , pp. 2591-2602
    • Sebastian, S.1
  • 206
    • 77957730038 scopus 로고    scopus 로고
    • The fslE homolog, FTL-0439 (fupA/B), mediates siderophore-dependent iron uptake in Francisella tularensis LVS
    • Sen B, Meeker A, Ramakrishnan G. 2010. The fslE homolog, FTL-0439 (fupA/B), mediates siderophore-dependent iron uptake in Francisella tularensis LVS. Infect. Immun. 78:4276-4285.
    • (2010) Infect. Immun. , vol.78 , pp. 4276-4285
    • Sen, B.1    Meeker, A.2    Ramakrishnan, G.3
  • 207
    • 84857195479 scopus 로고    scopus 로고
    • Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction
    • Shi CS, et al. 2012. Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction. Nat. Immunol. 13:255-263.
    • (2012) Nat. Immunol. , vol.13 , pp. 255-263
    • Shi, C.S.1
  • 208
    • 56149111288 scopus 로고    scopus 로고
    • Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism
    • Shirey KA, Cole LE, Keegan AD, Vogel SN. 2008. Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism. J. Immunol. 181:4159-4167.
    • (2008) J. Immunol. , vol.181 , pp. 4159-4167
    • Shirey, K.A.1    Cole, L.E.2    Keegan, A.D.3    Vogel, S.N.4
  • 209
    • 0037152173 scopus 로고    scopus 로고
    • Yersinia V-antigen exploits Toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression
    • Sing A, et al. 2002. Yersinia V-antigen exploits Toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression. J. Exp. Med. 196:1017-1024.
    • (2002) J. Exp. Med. , vol.196 , pp. 1017-1024
    • Sing, A.1
  • 210
    • 34748912454 scopus 로고    scopus 로고
    • Tularemia: History, epidemiology, pathogen physiology, and clinical manifestations
    • Sjöstedt A. 2007. Tularemia: history, epidemiology, pathogen physiology, and clinical manifestations. Ann. N. Y. Acad. Sci. 1105:1-29.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1105 , pp. 1-29
    • Sjöstedt, A.1
  • 211
    • 0028301218 scopus 로고
    • Neutrophils are critical for host defense against primary infection with the facultative intracellular bacterium Francisella tularensis in mice and participate in defense against reinfection
    • Sjostedt A, Conlan JW, North RJ. 1994. Neutrophils are critical for host defense against primary infection with the facultative intracellular bacterium Francisella tularensis in mice and participate in defense against reinfection. Infect. Immun. 62:2779-2783.
    • (1994) Infect. Immun. , vol.62 , pp. 2779-2783
    • Sjostedt, A.1    Conlan, J.W.2    North, R.J.3
  • 212
  • 213
    • 0024395660 scopus 로고
    • O antigen and lipid A phosphoryl groups in resistance of Salmonella typhimurium LT-2 to nonoxidative killing in human polymorphonuclear neutrophils
    • Stinavage P, Martin L, Spitznagel J. 1989. O antigen and lipid A phosphoryl groups in resistance of Salmonella typhimurium LT-2 to nonoxidative killing in human polymorphonuclear neutrophils. Infect. Immun. 57:3894-3900.
    • (1989) Infect. Immun. , vol.57 , pp. 3894-3900
    • Stinavage, P.1    Martin, L.2    Spitznagel, J.3
  • 214
    • 84862579338 scopus 로고    scopus 로고
    • The capBCA locus is required for intracellular growth of Francisella tularensis LVS
    • Su J, et al. 2011. The capBCA locus is required for intracellular growth of Francisella tularensis LVS. Front. Microbiol. 2:83.
    • (2011) Front. Microbiol. , vol.2 , pp. 83
    • Su, J.1
  • 215
    • 34249868441 scopus 로고    scopus 로고
    • Genome-wide identification of Francisella tularensis virulence determinants
    • Su J, et al. 2007. Genome-wide identification of Francisella tularensis virulence determinants. Infect. Immun. 75:3089-3101.
    • (2007) Infect. Immun. , vol.75 , pp. 3089-3101
    • Su, J.1
  • 216
    • 33744734682 scopus 로고    scopus 로고
    • Characterization of the siderophore of Francisella tularensis and role of fslA in siderophore production
    • Sullivan JT, Jeffery EF, Shannon JD, Ramakrishnan G. 2006. Characterization of the siderophore of Francisella tularensis and role of fslA in siderophore production. J. Bacteriol. 188:3785-3795.
    • (2006) J. Bacteriol. , vol.188 , pp. 3785-3795
    • Sullivan, J.T.1    Jeffery, E.F.2    Shannon, J.D.3    Ramakrishnan, G.4
  • 218
    • 50949133928 scopus 로고    scopus 로고
    • Francisella targets cholesterol-rich host cell membrane domains for entry into macrophages
    • Tamilselvam B, Daefler S. 2008. Francisella targets cholesterol-rich host cell membrane domains for entry into macrophages. J. Immunol. 180:8262-8271.
    • (2008) J. Immunol. , vol.180 , pp. 8262-8271
    • Tamilselvam, B.1    Daefler, S.2
  • 219
    • 0025944659 scopus 로고
    • Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism
    • Taylor MW, Feng GS. 1991. Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism. FASEB J. 5:2516-2522.
    • (1991) FASEB J. , vol.5 , pp. 2516-2522
    • Taylor, M.W.1    Feng, G.S.2
  • 220
    • 0037243609 scopus 로고    scopus 로고
    • Francisella tularensis inhibits Toll-like receptor-mediated activation of intracellular signalling and secretion of TNF-alpha and IL-1 from murine macrophages
    • Telepnev M, Golovliov I, Grundstrom T, Tarnvik A, Sjostedt A. 2003. Francisella tularensis inhibits Toll-like receptor-mediated activation of intracellular signalling and secretion of TNF-alpha and IL-1 from murine macrophages. Cell. Microbiol. 5:41-51.
    • (2003) Cell. Microbiol. , vol.5 , pp. 41-51
    • Telepnev, M.1    Golovliov, I.2    Grundstrom, T.3    Tarnvik, A.4    Sjostedt, A.5
  • 221
    • 42949086603 scopus 로고    scopus 로고
    • Identification of Francisella tularensis lipoproteins that stimulate the Toll-like receptor (TLR) 2/TLR1 heterodimer
    • Thakran S, et al. 2008. Identification of Francisella tularensis lipoproteins that stimulate the Toll-like receptor (TLR) 2/TLR1 heterodimer. J. Biol. Chem. 283:3751-3760.
    • (2008) J. Biol. Chem. , vol.283 , pp. 3751-3760
    • Thakran, S.1
  • 222
    • 33845979136 scopus 로고    scopus 로고
    • The immunologically distinct O antigens from Francisella tularensis subspecies tularensis and Francisella novicida are both virulence determinants and protective antigens
    • Thomas RM, et al. 2007. The immunologically distinct O antigens from Francisella tularensis subspecies tularensis and Francisella novicida are both virulence determinants and protective antigens. Infect. Immun. 75:371-378.
    • (2007) Infect. Immun. , vol.75 , pp. 371-378
    • Thomas, R.M.1
  • 223
    • 7944220803 scopus 로고    scopus 로고
    • Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition
    • Travassos LH, et al. 2004. Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. EMBO Rep. 5:1000-1006.
    • (2004) EMBO Rep. , vol.5 , pp. 1000-1006
    • Travassos, L.H.1
  • 224
    • 28444439557 scopus 로고    scopus 로고
    • A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccine
    • Twine S, et al. 2005. A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccine. Infect. Immun. 73:8345-8352.
    • (2005) Infect. Immun. , vol.73 , pp. 8345-8352
    • Twine, S.1
  • 225
    • 78049394393 scopus 로고    scopus 로고
    • Mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence
    • Ulland TK, et al. 2010. Mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence. J. Immunol. 185:2670-2674.
    • (2010) J. Immunol. , vol.185 , pp. 2670-2674
    • Ulland, T.K.1
  • 226
    • 0036216769 scopus 로고    scopus 로고
    • Phagocytosis of microbes: Complexity in action
    • Underhill DM, Ozinsky A. 2002. Phagocytosis of microbes: complexity in action. Annu. Rev. Immunol. 20:825-852.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 825-852
    • Underhill, D.M.1    Ozinsky, A.2
  • 227
    • 65249108735 scopus 로고    scopus 로고
    • Autophagy genes in immunity
    • Virgin HW, Levine B. 2009. Autophagy genes in immunity. Nat. Immunol. 10:461-470.
    • (2009) Nat. Immunol. , vol.10 , pp. 461-470
    • Virgin, H.W.1    Levine, B.2
  • 228
    • 0025372570 scopus 로고
    • TolC, an Escherichia coli outer membrane protein required for hemolysin secretion
    • Wandersman C, Delepelaire P. 1990. TolC, an Escherichia coli outer membrane protein required for hemolysin secretion. Proc. Natl. Acad. Sci. U. S. A. 87:4776-4780.
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 4776-4780
    • Wandersman, C.1    Delepelaire, P.2
  • 229
    • 0034112116 scopus 로고    scopus 로고
    • Bacterial heme sources: The role of heme, hemoprotein receptors and hemophores
    • Wandersman C, Stojiljkovic I. 2000. Bacterial heme sources: the role of heme, hemoprotein receptors and hemophores. Curr. Opin. Microbiol. 3:215-220.
    • (2000) Curr. Opin. Microbiol. , vol.3 , pp. 215-220
    • Wandersman, C.1    Stojiljkovic, I.2
  • 231
    • 33845256842 scopus 로고    scopus 로고
    • Structure and biosynthesis of free lipid A molecules that replace lipopolysaccharide in Francisella tularensis subsp. novicida
    • Wang X, et al. 2006. Structure and biosynthesis of free lipid A molecules that replace lipopolysaccharide in Francisella tularensis subsp. novicida. Biochemistry 45:14427-14440.
    • (2006) Biochemistry , vol.45 , pp. 14427-14440
    • Wang, X.1
  • 232
    • 0016227934 scopus 로고
    • Iron and susceptibility to infectious disease
    • Weinberg ED. 1974. Iron and susceptibility to infectious disease. Science 184:952-956.
    • (1974) Science , vol.184 , pp. 952-956
    • Weinberg, E.D.1
  • 233
    • 34347270217 scopus 로고    scopus 로고
    • In vivo negative selection screen identifies genes required for Francisella virulence
    • Weiss DS, et al. 2007. In vivo negative selection screen identifies genes required for Francisella virulence. Proc. Natl. Acad. Sci. U. S. A. 104:6037-6042.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 6037-6042
    • Weiss, D.S.1
  • 234
    • 0022295839 scopus 로고
    • Inhibition of complement-mediated opsonization and phagocytosis of Streptococcus pyogenes by D fragments of fibrinogen and fibrin bound to cell surface M protein
    • Whitnack E, Beachey EH. 1985. Inhibition of complement-mediated opsonization and phagocytosis of Streptococcus pyogenes by D fragments of fibrinogen and fibrin bound to cell surface M protein. J. Exp. Med. 162:1983-1997.
    • (1985) J. Exp. Med. , vol.162 , pp. 1983-1997
    • Whitnack, E.1    Beachey, E.H.2
  • 235
    • 70350446682 scopus 로고    scopus 로고
    • Francisella tularensis induces extensive caspase-3 activation and apoptotic cell death in the tissues of infected mice
    • Wickstrum JR, et al. 2009. Francisella tularensis induces extensive caspase-3 activation and apoptotic cell death in the tissues of infected mice. Infect. Immun. 77:4827-4836.
    • (2009) Infect. Immun. , vol.77 , pp. 4827-4836
    • Wickstrum, J.R.1
  • 236
    • 70350437274 scopus 로고    scopus 로고
    • Francisella tularensis induces ubiquitin-dependent major histocompatibility complex class II degradation in activated macrophages
    • Wilson JE, Katkere B, Drake JR. 2009. Francisella tularensis induces ubiquitin-dependent major histocompatibility complex class II degradation in activated macrophages. Infect. Immun. 77:4953-4965.
    • (2009) Infect. Immun. , vol.77 , pp. 4953-4965
    • Wilson, J.E.1    Katkere, B.2    Drake, J.R.3
  • 237
    • 33846928937 scopus 로고    scopus 로고
    • Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like response
    • Woolard MD, et al. 2007. Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like response. J. Immunol. 178:2065-2074.
    • (2007) J. Immunol. , vol.178 , pp. 2065-2074
    • Woolard, M.D.1
  • 238
    • 0018179447 scopus 로고
    • Induction of pulmonary indoleamine 2,3-dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide
    • Yoshida R, Hayaishi O. 1978. Induction of pulmonary indoleamine 2,3-dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide. Proc. Natl. Acad. Sci. U. S. A. 75:3998-4000.
    • (1978) Proc. Natl. Acad. Sci. U. S. A. , vol.75 , pp. 3998-4000
    • Yoshida, R.1    Hayaishi, O.2
  • 239
    • 0022512370 scopus 로고
    • Interferon: A mediator of indoleamine 2,3-dioxygenase induction by lipopolysaccharide, poly(I) X poly(C), and pokeweed mitogen in mouse lung
    • Yoshida R, Oku T, Imanishi J, Kishida T, Hayaishi O. 1986. Interferon: a mediator of indoleamine 2,3-dioxygenase induction by lipopolysaccharide, poly(I) X poly(C), and pokeweed mitogen in mouse lung. Arch. Biochem. Biophys. 249:596-604.
    • (1986) Arch. Biochem. Biophys. , vol.249 , pp. 596-604
    • Yoshida, R.1    Oku, T.2    Imanishi, J.3    Kishida, T.4    Hayaishi, O.5
  • 240
    • 43449125594 scopus 로고    scopus 로고
    • The presence of infectious extracellular Francisella tularensis subsp. novicida in murine plasma after pulmonary challenge
    • Yu JJ, et al. 2008. The presence of infectious extracellular Francisella tularensis subsp. novicida in murine plasma after pulmonary challenge. Eur. J. Clin. Microbiol. Infect. Dis. 27:323-325.
    • (2008) Eur. J. Clin. Microbiol. Infect. Dis. , vol.27 , pp. 323-325
    • Yu, J.J.1
  • 241
    • 79960675331 scopus 로고    scopus 로고
    • Host-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity
    • Zarrella TM, et al. 2011. Host-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity. PLoS One 6:e22335.
    • (2011) PLoS One , vol.6
    • Zarrella, T.M.1
  • 242
    • 2942744657 scopus 로고    scopus 로고
    • Double mechanism for apical tryptophan depletion in polarized human bronchial epithelium
    • Zegarra-Moran O, et al. 2004. Double mechanism for apical tryptophan depletion in polarized human bronchial epithelium. J. Immunol. 173:542-549.
    • (2004) J. Immunol. , vol.173 , pp. 542-549
    • Zegarra-Moran, O.1
  • 243
    • 33744539146 scopus 로고    scopus 로고
    • IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways
    • Zhao J, et al. 2006. IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. J. Biol. Chem. 281:10073-10080.
    • (2006) J. Biol. Chem. , vol.281 , pp. 10073-10080
    • Zhao, J.1
  • 244
    • 78349274608 scopus 로고    scopus 로고
    • A two-component Kdo hydrolase in the inner membrane of Francisella novicida
    • Zhao J, Raetz CR. 2010. A two-component Kdo hydrolase in the inner membrane of Francisella novicida. Mol. Microbiol. 78:820-836.
    • (2010) Mol. Microbiol. , vol.78 , pp. 820-836
    • Zhao, J.1    Raetz, C.R.2


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