Indoleamine 2,3-dioxygenase 1 is a lung-specific innate immune defense mechanism that inhibits growth of Francisella tularensis tryptophan auxotrophs

Infection and Immunity

Volumn 78, Issue 6, 2010, Pages 2723-2733

  Peng, Kaitian ^a   Monack, Denise M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE 1; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUXOTROPHIC MUTANT; BACTERIAL GENE; BACTERIAL GROWTH; BIOSYNTHESIS; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISEASE MODEL; FEMALE; FRANCISELLA; FRANCISELLA NOVICIDA; FRANCISELLA NOVICIDA INFECTION; FRANCISELLA TULARENSIS; GENE IDENTIFICATION; GRAM NEGATIVE INFECTION; INNATE IMMUNITY; LUNG INFECTION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE; TULAREMIA;

ANIMALS; BIOSYNTHETIC PATHWAYS; CELL LINE; COLONY COUNT, MICROBIAL; FEMALE; FRANCISELLA TULARENSIS; GENE EXPRESSION PROFILING; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; LUNG; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SPLEEN; STREPTOCOCCUS PNEUMONIAE; TRYPTOPHAN; VIRULENCE FACTORS;

EID: 77952718220     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00008-10     Document Type: Article

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