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Volumn 187, Issue 4, 2011, Pages 1845-1855

IFN-β mediates suppression of IL-12p40 in human dendritic cells following infection with virulent Francisella tularensis

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INFLAMMASOME; INTERLEUKIN 12P40; TUMOR NECROSIS FACTOR ALPHA;

EID: 80051920695     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100377     Document Type: Article
Times cited : (31)

References (55)
  • 1
    • 19744368094 scopus 로고    scopus 로고
    • Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis
    • DOI 10.1128/IAI.73.6.3219-3227.2005
    • Coburn, B., Y. Li, D. Owen, B. A. Vallance, and B. B. Finlay. 2005. Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis. Infect. Immun. 73: 3219-3227. (Pubitemid 40745861)
    • (2005) Infection and Immunity , vol.73 , Issue.6 , pp. 3219-3227
    • Coburn, B.1    Li, Y.2    Owen, D.3    Vallance, B.A.4    Finlay, B.B.5
  • 2
    • 17144405602 scopus 로고    scopus 로고
    • TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins
    • Faure, K., T. Sawa, T. Ajayi, J. Fujimoto, K. Moriyama, N. Shime, and J. P. Wiener-Kronish. 2004. TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins. Respir. Res. 5: 1.
    • (2004) Respir. Res. , vol.5 , pp. 1
    • Faure, K.1    Sawa, T.2    Ajayi, T.3    Fujimoto, J.4    Moriyama, K.5    Shime, N.6    Wiener-Kronish, J.P.7
  • 3
    • 0347122085 scopus 로고    scopus 로고
    • Ebola and Marburg Viruses Replicate in Monocyte-Derived Dendritic Cells without Inducing the Production of Cytokines and Full Maturation
    • DOI 10.1086/379199
    • Bosio, C. M., M. J. Aman, C. Grogan, R. Hogan, G. Ruthel, D. Negley, M. Mohamadzadeh, S. Bavari, and A. Schmaljohn. 2003. Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation. J. Infect. Dis. 188: 1630-1638. (Pubitemid 38010672)
    • (2003) Journal of Infectious Diseases , vol.188 , Issue.11 , pp. 1630-1638
    • Bosio, C.M.1    Aman, M.J.2    Grogan, C.3    Hogan, R.4    Ruthel, G.5    Negley, D.6    Mohamadzadeh, M.7    Bavari, S.8    Schmaljohn, A.9
  • 4
    • 33947702199 scopus 로고    scopus 로고
    • Active suppression of the pulmonary immune response by Francisella tularensis Schu4
    • Bosio, C. M., H. Bielefeldt-Ohmann, and J. T. Belisle. 2007. Active suppression of the pulmonary immune response by Francisella tularensis Schu4. J. Immunol. 178: 4538-4547. (Pubitemid 46492406)
    • (2007) Journal of Immunology , vol.178 , Issue.7 , pp. 4538-4547
    • Bosio, C.M.1    Bielefeldt-Ohmann, H.2    Belisle, J.T.3
  • 6
    • 58449133177 scopus 로고    scopus 로고
    • Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4
    • Chase, J. C., J. Celli, and C. M. Bosio. 2009. Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4. Infect. Immun. 77: 180-195.
    • (2009) Infect. Immun. , vol.77 , pp. 180-195
    • Chase, J.C.1    Celli, J.2    Bosio, C.M.3
  • 7
    • 0004198502 scopus 로고
    • University of Montana, University of Montana Foundation, Missoula, MT
    • Jellison, W. L. 1974. Tularemia in North America, 1930-1974. University of Montana, University of Montana Foundation, Missoula, MT.
    • (1974) Tularemia in North America, 1930-1974
    • Jellison, W.L.1
  • 9
    • 0001130195 scopus 로고
    • Prophylactic effectiveness of live and killed tularemia vaccines. I. Production of vaccine and evaluation in the white mouse and guinea pig
    • Eigelsbach, H. T., and C. M. Downs. 1961. Prophylactic effectiveness of live and killed tularemia vaccines. I. Production of vaccine and evaluation in the white mouse and guinea pig. J. Immunol. 87: 415-425.
    • (1961) J. Immunol. , vol.87 , pp. 415-425
    • Eigelsbach, H.T.1    Downs, C.M.2
  • 11
    • 33751511700 scopus 로고    scopus 로고
    • Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells (DC): Uptake of Francisella leads to activation of immature DC and intracellular survival of the bacteria
    • DOI 10.1189/jlb.1205755
    • Ben Nasr, A., J. Haithcoat, J. E. Masterson, J. S. Gunn, T. Eaves-Pyles, and G. R. Klimpel. 2006. Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells (DC): Uptake of Francisella leads to activation of immature DC and intracellular survival of the bacteria. J. Leukoc. Biol. 80: 774-786. (Pubitemid 44835896)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.4 , pp. 774-786
    • Nasr, A.B.1    Haithcoat, J.2    Masterson, J.E.3    Gunn, J.S.4    Eaves-Pyles, T.5    Klimpel, G.R.6
  • 13
    • 45549087455 scopus 로고    scopus 로고
    • Macrophage proinflammatory response to Francisella tularensis live vaccine strain requires coordination of multiple signaling pathways
    • Cole, L. E., A. Santiago, E. Barry, T. J. Kang, K. A. Shirey, Z. J. Roberts, K. L. Elkins, A. S. Cross, and S. N. Vogel. 2008. Macrophage proinflammatory response to Francisella tularensis live vaccine strain requires coordination of multiple signaling pathways. J. Immunol. 180: 6885-6891.
    • (2008) J. Immunol. , vol.180 , pp. 6885-6891
    • Cole, L.E.1    Santiago, A.2    Barry, E.3    Kang, T.J.4    Shirey, K.A.5    Roberts, Z.J.6    Elkins, K.L.7    Cross, A.S.8    Vogel, S.N.9
  • 16
    • 73449132254 scopus 로고    scopus 로고
    • The presence of CD14 overcomes evasion of innate immune responses by virulent Francisella tularensis in human dendritic cells in vitro and pulmonary cells in vivo
    • Chase, J. C., and C. M. Bosio. 2010. The presence of CD14 overcomes evasion of innate immune responses by virulent Francisella tularensis in human dendritic cells in vitro and pulmonary cells in vivo. Infect. Immun. 78: 154-167.
    • (2010) Infect. Immun. , vol.78 , pp. 154-167
    • Chase, J.C.1    Bosio, C.M.2
  • 17
    • 57349126161 scopus 로고    scopus 로고
    • The early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression
    • Chong, A., T. D. Wehrly, V. Nair, E. R. Fischer, J. R. Barker, K. E. Klose, and J. Celli. 2008. The early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression. Infect. Immun. 76: 5488-5499.
    • (2008) Infect. Immun. , vol.76 , pp. 5488-5499
    • Chong, A.1    Wehrly, T.D.2    Nair, V.3    Fischer, E.R.4    Barker, J.R.5    Klose, K.E.6    Celli, J.7
  • 18
    • 0036178266 scopus 로고    scopus 로고
    • Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback
    • DOI 10.1089/107999002753452692
    • Levy, D. E., I. Marié, E. Smith, and A. Prakash. 2002. Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback. J. Interferon Cytokine Res. 22: 87-93. (Pubitemid 34161286)
    • (2002) Journal of Interferon and Cytokine Research , vol.22 , Issue.1 , pp. 87-93
    • Levy, D.E.1    Marie, I.2    Smith, E.3    Prakash, A.4
  • 19
    • 42949086603 scopus 로고    scopus 로고
    • Identification of Francisella tularensis lipoproteins that stimulate the tolllike receptor (TLR) 2/TLR1 heterodimer
    • Thakran, S., H. Li, C. L. Lavine, M. A. Miller, J. E. Bina, X. R. Bina, and F. Re. 2008. Identification of Francisella tularensis lipoproteins that stimulate the tolllike receptor (TLR) 2/TLR1 heterodimer. J. Biol. Chem. 283: 3751-3760.
    • (2008) J. Biol. Chem. , vol.283 , pp. 3751-3760
    • Thakran, S.1    Li, H.2    Lavine, C.L.3    Miller, M.A.4    Bina, J.E.5    Bina, X.R.6    Re, F.7
  • 20
    • 70350441863 scopus 로고    scopus 로고
    • Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands
    • Barbalat, R., L. Lau, R. M. Locksley, and G. M. Barton. 2009. Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands. Nat. Immunol. 10: 1200-1207.
    • (2009) Nat. Immunol. , vol.10 , pp. 1200-1207
    • Barbalat, R.1    Lau, L.2    Locksley, R.M.3    Barton, G.M.4
  • 21
    • 40949134086 scopus 로고    scopus 로고
    • TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta
    • DOI 10.1038/ni1569, PII NI1569
    • Kagan, J. C., T. Su, T. Horng, A. Chow, S. Akira, and R. Medzhitov. 2008. TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferonbeta. Nat. Immunol. 9: 361-368. (Pubitemid 351405105)
    • (2008) Nature Immunology , vol.9 , Issue.4 , pp. 361-368
    • Kagan, J.C.1    Su, T.2    Horng, T.3    Chow, A.4    Akira, S.5    Medzhitov, R.6
  • 22
    • 2542552050 scopus 로고    scopus 로고
    • Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages
    • DOI 10.1128/IAI.72.6.3204-3217.2004
    • Clemens, D. L., B. Y. Lee, and M. A. Horwitz. 2004. Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages. Infect. Immun. 72: 3204-3217. (Pubitemid 38697741)
    • (2004) Infection and Immunity , vol.72 , Issue.6 , pp. 3204-3217
    • Clemens, D.L.1    Lee, B.-Y.2    Horwitz, M.A.3
  • 23
    • 0038731144 scopus 로고    scopus 로고
    • Linking Toll-like receptors to IFN-alpha/beta expression
    • DOI 10.1038/ni0503-432
    • Barton, G. M., and R. Medzhitov. 2003. Linking Toll-like receptors to IFNalpha/ beta expression. Nat. Immunol. 4: 432-433. (Pubitemid 36592435)
    • (2003) Nature Immunology , vol.4 , Issue.5 , pp. 432-433
    • Barton, G.M.1    Medzhitov, R.2
  • 24
    • 0042123694 scopus 로고    scopus 로고
    • Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells
    • DOI 10.1084/jem.20030162
    • Lund, J., A. Sato, S. Akira, R. Medzhitov, and A. Iwasaki. 2003. Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. J. Exp. Med. 198: 513-520. (Pubitemid 36976063)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.3 , pp. 513-520
    • Lund, J.1    Sato, A.2    Akira, S.3    Medzhitov, R.4    Iwasaki, A.5
  • 25
    • 33749151638 scopus 로고    scopus 로고
    • Collaborative action of NF-kappaB and p38 MAPK is involved in CpG DNA-induced IFN-alpha and chemokine production in human plasmacytoid dendritic cells
    • Osawa, Y., S. Iho, R. Takauji, H. Takatsuka, S. Yamamoto, T. Takahashi, S. Horiguchi, Y. Urasaki, T. Matsuki, and S. Fujieda. 2006. Collaborative action of NF-kappaB and p38 MAPK is involved in CpG DNA-induced IFN-alpha and chemokine production in human plasmacytoid dendritic cells. J. Immunol. 177: 4841-4852. (Pubitemid 44469820)
    • (2006) Journal of Immunology , vol.177 , Issue.7 , pp. 4841-4852
    • Osawa, Y.1    Iho, S.2    Takauji, R.3    Takatsuka, H.4    Yamamoto, S.5    Takahashi, T.6    Horiguchi, S.7    Urasaki, Y.8    Matsuki, T.9    Fejieda, S.10
  • 26
    • 65449134827 scopus 로고    scopus 로고
    • Francisella tularensis phagosomal escape does not require acidification of the phagosome
    • Clemens, D. L., B. Y. Lee, and M. A. Horwitz. 2009. Francisella tularensis phagosomal escape does not require acidification of the phagosome. Infect. Immun. 77: 1757-1773.
    • (2009) Infect. Immun. , vol.77 , pp. 1757-1773
    • Clemens, D.L.1    Lee, B.Y.2    Horwitz, M.A.3
  • 27
    • 0028953912 scopus 로고
    • Growth of Francisella tularensis LVS in macrophages: The acidic intracellular compartment provides essential iron required for growth
    • Fortier, A. H., D. A. Leiby, R. B. Narayanan, E. Asafoadjei, R. M. Crawford, C. A. Nacy, and M. S. Meltzer. 1995. Growth of Francisella tularensis LVS in macrophages: The acidic intracellular compartment provides essential iron required for growth. Infect. Immun. 63: 1478-1483.
    • (1995) Infect. Immun. , vol.63 , pp. 1478-1483
    • Fortier, A.H.1    Leiby, D.A.2    Narayanan, R.B.3    Asafoadjei, E.4    Crawford, R.M.5    Nacy, C.A.6    Meltzer, M.S.7
  • 29
    • 34249044447 scopus 로고    scopus 로고
    • Type I interferon signaling is required for activation of the inflammasome during Francisella infection
    • DOI 10.1084/jem.20062665
    • Henry, T., A. Brotcke, D. S. Weiss, L. J. Thompson, and D. M. Monack. 2007. Type I interferon signaling is required for activation of the inflammasome during Francisella infection. J. Exp. Med. 204: 987-994. (Pubitemid 46798143)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.5 , pp. 987-994
    • Henry, T.1    Brotcke, A.2    Weiss, D.S.3    Thompson, L.J.4    Monack, D.M.5
  • 31
    • 25444495693 scopus 로고    scopus 로고
    • The Yin and Yang of type I interferon activity in bacterial infection
    • DOI 10.1038/nri1684, PII NRI1684
    • Decker, T., M. Müller, and S. Stockinger. 2005. The yin and yang of type I interferon activity in bacterial infection. Nat. Rev. Immunol. 5: 675-687. (Pubitemid 43086170)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.9 , pp. 675-687
    • Decker, T.1    Muller, M.2    Stockinger, S.3
  • 32
    • 0032080850 scopus 로고    scopus 로고
    • Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell development
    • McRae, B. L., R. T. Semnani, M. P. Hayes, and G. A. Van Seventer. 1998. Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell development. J. Immunol. 160: 4298-4304. (Pubitemid 28217285)
    • (1998) Journal of Immunology , vol.160 , Issue.9 , pp. 4298-4304
    • McRae, B.L.1    Semnani, R.T.2    Hayes, M.P.3    Van Seventer, G.A.4
  • 33
    • 33745064871 scopus 로고    scopus 로고
    • Interferons limit inflammatory responses by induction of tristetraprolin
    • DOI 10.1182/blood-2005-07-3058
    • Sauer, I., B. Schaljo, C. Vogl, I. Gattermeier, T. Kolbe, M. Müller, P. J. Blackshear, and P. Kovarik. 2006. Interferons limit inflammatory responses by induction of tristetraprolin. Blood 107: 4790-4797. (Pubitemid 43882630)
    • (2006) Blood , vol.107 , Issue.12 , pp. 4790-4797
    • Sauer, I.1    Schaljo, B.2    Vogl, C.3    Gattermeier, I.4    Kolbe, T.5    Muller, M.6    Blackshear, P.J.7    Kovarik, P.8
  • 34
    • 0242412154 scopus 로고    scopus 로고
    • Timing of IFN-beta Exposure during Human Dendritic Cell Maturation and Naive Th Cell Stimulation Has Contrasting Effects on Th1 Subset Generation: A Role for IFN-beta-Mediated Regulation of IL-12 Family Cytokines and IL-18 in Naive Th Cell Differentiation
    • Nagai, T., O. Devergne, T. F. Mueller, D. L. Perkins, J. M. Van Seventer, and G. A. Van Seventer. 2003. Timing of IFN-beta exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: A role for IFN-beta-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation. J. Immunol. 171: 5233-5243. (Pubitemid 37432808)
    • (2003) Journal of Immunology , vol.171 , Issue.10 , pp. 5233-5243
    • Nagai, T.1    Devergne, O.2    Mueller, T.F.3    Perkins, D.L.4    Van Seventer, J.M.5    Van Seventer, G.A.6
  • 35
    • 0036890125 scopus 로고    scopus 로고
    • Interferon-beta differentially regulates expression of the IL-12 family members p35, p40, p19 and EBI3 in activated human dendritic cells
    • DOI 10.1016/S0165-5728(02)00362-4, PII S0165572802003624
    • Van Seventer, J. M., T. Nagai, and G. A. Van Seventer. 2002. Interferon-beta differentially regulates expression of the IL-12 family members p35, p40, p19 and EBI3 in activated human dendritic cells. J. Neuroimmunol. 133: 60-71. (Pubitemid 35346729)
    • (2002) Journal of Neuroimmunology , vol.133 , Issue.1-2 , pp. 60-71
    • Van Seventer, J.M.1    Nagai, T.2    Van Seventer, G.A.3
  • 38
    • 0037243609 scopus 로고    scopus 로고
    • Francisella tularensis inhibits Toll-like receptor-mediated activation of intracellular signalling and secretion of TNF-alpha and IL-1 from murine macrophages
    • DOI 10.1046/j.1462-5822.2003.00251.x
    • Telepnev, M., I. Golovliov, T. Grundström, A. Tärnvik, and A. Sjöstedt. 2003. Francisella tularensis inhibits Toll-like receptor-mediated activation of intracellular signalling and secretion of TNF-alpha and IL-1 from murine macrophages. Cell. Microbiol. 5: 41-51. (Pubitemid 36395119)
    • (2003) Cellular Microbiology , vol.5 , Issue.1 , pp. 41-51
    • Telepnev, M.1    Golovliov, I.2    Grundstrom, T.3    Tarnvik, A.4    Sjostedt, A.5
  • 39
    • 19544395035 scopus 로고    scopus 로고
    • Francisella tularensis LVS initially activates but subsequently down-regulates intracellular signaling and cytokine secretion in mouse monocytic and human peripheral blood mononuclear cells
    • DOI 10.1016/j.micpath.2005.02.003, PII S0882401005000239
    • Telepnev, M., I. Golovliov, and A. Sjöstedt. 2005. Francisella tularensis LVS initially activates but subsequently down-regulates intracellular signaling and cytokine secretion in mouse monocytic and human peripheral blood mononuclear cells. Microb. Pathog. 38: 239-247. (Pubitemid 40733553)
    • (2005) Microbial Pathogenesis , vol.38 , Issue.5-6 , pp. 239-247
    • Telepnev, M.1    Golovliov, I.2    Sjostedt, A.3
  • 40
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • DOI 10.1038/32588
    • Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252. (Pubitemid 28155090)
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 41
    • 0035838979 scopus 로고    scopus 로고
    • Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity
    • Liu, Y. J. 2001. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106: 259-262.
    • (2001) Cell , vol.106 , pp. 259-262
    • Liu, Y.J.1
  • 42
    • 57149084078 scopus 로고    scopus 로고
    • Interrelationship between dendritic cell trafficking and Francisella tularensis dissemination following airway infection
    • Bar-Haim, E., O. Gat, G. Markel, H. Cohen, A. Shafferman, and B. Velan. 2008. Interrelationship between dendritic cell trafficking and Francisella tularensis dissemination following airway infection. PLoS Pathog. 4: e1000211.
    • (2008) PLoS Pathog. , vol.4
    • Bar-Haim, E.1    Gat, O.2    Markel, G.3    Cohen, H.4    Shafferman, A.5    Velan, B.6
  • 43
    • 27744547036 scopus 로고    scopus 로고
    • Francisella tularensis induces aberrant activation of pulmonary dendritic cells
    • Bosio, C. M., and S. W. Dow. 2005. Francisella tularensis induces aberrant activation of pulmonary dendritic cells. J. Immunol. 175: 6792-6801. (Pubitemid 41598924)
    • (2005) Journal of Immunology , vol.175 , Issue.10 , pp. 6792-6801
    • Bosio, C.M.1    Dow, S.W.2
  • 44
    • 55449088081 scopus 로고    scopus 로고
    • Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus
    • Phipps-Yonas, H., J. Seto, S. C. Sealfon, T. M. Moran, and A. Fernandez-Sesma. 2008. Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus. PLoS Pathog. 4: e1000193.
    • (2008) PLoS Pathog. , vol.4
    • Phipps-Yonas, H.1    Seto, J.2    Sealfon, S.C.3    Moran, T.M.4    Fernandez-Sesma, A.5
  • 45
    • 41849089157 scopus 로고    scopus 로고
    • Molecular immunology of experimental primary tularemia in mice infected by respiratory or intradermal routes with type A Francisella tularensis
    • Conlan, J. W., X. Zhao, G. Harris, H. Shen, M. Bolanowski, C. Rietz, A. Sjostedt, and W. Chen. 2008. Molecular immunology of experimental primary tularemia in mice infected by respiratory or intradermal routes with type A Francisella tularensis. Mol. Immunol. 45: 2962-2969.
    • (2008) Mol. Immunol. , vol.45 , pp. 2962-2969
    • Conlan, J.W.1    Zhao, X.2    Harris, G.3    Shen, H.4    Bolanowski, M.5    Rietz, C.6    Sjostedt, A.7    Chen, W.8
  • 46
    • 0034944385 scopus 로고    scopus 로고
    • Type I interferons and IL-12: Convergence and cross-regulation among mediators of cellular immunity
    • DOI 10.1002/1521-4141(200107)31:7<2026::AID-IMMU2026>3.0.CO;2-U
    • Byrnes, A. A., X. Ma, P. Cuomo, K. Park, L. Wahl, S. F. Wolf, H. Zhou, G. Trinchieri, and C. L. Karp. 2001. Type I interferons and IL-12: Convergence and cross-regulation among mediators of cellular immunity. Eur. J. Immunol. 31: 2026-2034. (Pubitemid 32640718)
    • (2001) European Journal of Immunology , vol.31 , Issue.7 , pp. 2026-2034
    • Byrnes, A.A.1    Xiaojing, M.2    Cuomo, P.3    Park, K.4    Wahl, L.5    Wolf, S.F.6    Zhou, H.7    Trinchieri, G.8    Karp, C.L.9
  • 47
    • 0034982136 scopus 로고    scopus 로고
    • Interferon-beta in multiple sclerosis: Altering the balance of interleukin-12 and interleukin-10?
    • DOI 10.1097/00019052-200106000-00016
    • Karp, C. L., A. H. Van Boxel-Dezaire, A. A. Byrnes, and L. Nagelkerken. 2001. Interferon-beta in multiple sclerosis: Altering the balance of interleukin-12 and interleukin-10? Curr. Opin. Neurol. 14: 361-368. (Pubitemid 32510602)
    • (2001) Current Opinion in Neurology , vol.14 , Issue.3 , pp. 361-368
    • Karp, C.L.1    Van Boxel-Dezaire, A.H.H.2    Byrnes, A.A.3    Nagelkerken, L.4
  • 48
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder, K., and J. Tschopp. 2010. The inflammasomes. Cell 140: 821-832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 50
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
    • Ding, A. H., C. F. Nathan, and D. J. Stuehr. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141: 2407-2412.
    • (1988) J. Immunol. , vol.141 , pp. 2407-2412
    • Ding, A.H.1    Nathan, C.F.2    Stuehr, D.J.3
  • 51
    • 55849122258 scopus 로고    scopus 로고
    • RipA, a cytoplasmic membrane protein conserved among Francisella species, is required for intracellular survival
    • Fuller, J. R., R. R. Craven, J. D. Hall, T. M. Kijek, S. Taft-Benz, and T. H. Kawula. 2008. RipA, a cytoplasmic membrane protein conserved among Francisella species, is required for intracellular survival. Infect. Immun. 76: 4934-4943.
    • (2008) Infect. Immun. , vol.76 , pp. 4934-4943
    • Fuller, J.R.1    Craven, R.R.2    Hall, J.D.3    Kijek, T.M.4    Taft-Benz, S.5    Kawula, T.H.6
  • 53
    • 38449100329 scopus 로고    scopus 로고
    • Type I interferons as anti-inflammatory mediators
    • Benveniste, E. N., and H. Qin. 2007. Type I interferons as anti-inflammatory mediators. Sci. STKE 2007: pe70.
    • (2007) Sci. STKE , vol.2007
    • Benveniste, E.N.1    Qin, H.2
  • 54
    • 0034954034 scopus 로고    scopus 로고
    • Interferons alpha and beta as immune regulators - A new look
    • DOI 10.1016/S1074-7613(01)00154-6
    • Biron, C. A. 2001. Interferons alpha and beta as immune regulators - a new look. Immunity 14: 661-664. (Pubitemid 32592413)
    • (2001) Immunity , vol.14 , Issue.6 , pp. 661-664
    • Biron, C.A.1
  • 55
    • 0036127059 scopus 로고    scopus 로고
    • In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70
    • DOI 10.1128/IAI.70.4.1936-1948.2002
    • Elkins, K. L., A. Cooper, S. M. Colombini, S. C. Cowley, and T. L. Kieffer. 2002. In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70. Infect. Immun. 70: 1936-1948. (Pubitemid 34242194)
    • (2002) Infection and Immunity , vol.70 , Issue.4 , pp. 1936-1948
    • Elkins, K.L.1    Cooper, A.2    Colombini, S.M.3    Cowley, S.C.4    Kieffer, T.L.5


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