A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccine

Infection and Immunity

Volumn 73, Issue 12, 2005, Pages 8345-8352

  Twine, Susan ^a   Byström, Mona ^b   Chen, Wangxue ^a   Forsman, Mats ^b   Golovliov, Igor ^c   Johansson, Anders ^b,c   Kelly, John ^a   Lindgren, Helena ^c   Svensson, Kerstin ^b   Zingmark, Carl ^c   Conlan, Wayne ^a   Sjöstedt, Anders ^c  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b SWEDISH DEFENCE RESEARCH AGENCY   (Sweden)

^c UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

LIVE VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM MUTANT; COLONY FORMING UNIT; CONTROLLED STUDY; DELETION MUTANT; FEMALE; FRANCISELLA TULARENSIS; LETHAL DOSE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS;

ADMINISTRATION, CUTANEOUS; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BACTERIAL VACCINES; FEMALE; FRANCISELLA TULARENSIS; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MUTATION; PROTEOMICS; SKIN; TULAREMIA; VACCINES, ATTENUATED; VIRULENCE;

EID: 28444439557     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.12.8345-8352.2005     Document Type: Article

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