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Volumn 7, Issue 7, 2005, Pages 957-967

Modulation of biogenesis of the Francisella tularensis subsp. novicida-containing phagosome in quiescent human macrophages and its maturation into a phagolysosome upon activation by IFN-γ

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; CATHEPSIN D; GAMMA INTERFERON; GOLD; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; OVALBUMIN;

EID: 21344436430     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2005.00529.x     Document Type: Article
Times cited : (120)

References (58)
  • 2
    • 0036165063 scopus 로고    scopus 로고
    • A phagosome of one's own: A microbial guide to life in the macrophage
    • Amer, A.O., and Swanson, M.S. (2002) A phagosome of one's own: a microbial guide to life in the macrophage. Curr Opin Microbiol 5: 56-61.
    • (2002) Curr. Opin. Microbiol. , vol.5 , pp. 56-61
    • Amer, A.O.1    Swanson, M.S.2
  • 3
    • 0024933552 scopus 로고
    • The requirement for gamma interferon in resistance of mice to experimental tularemia
    • Anthony, L.S.D., Ghadirian, E., Nestel, F.P., and Kongshavn, P.A. (1989) The requirement for gamma interferon in resistance of mice to experimental tularemia. Microb Pathog 7: 421-428.
    • (1989) Microb. Pathog. , vol.7 , pp. 421-428
    • Anthony, L.S.D.1    Ghadirian, E.2    Nestel, F.P.3    Kongshavn, P.A.4
  • 4
    • 0025834766 scopus 로고
    • Growth of Francisella spp. in rodent macrophages
    • Anthony, L.S.D., Burke, R.D., and Nano, F.E. (1991) Growth of Francisella spp. in rodent macrophages. Infect Immun 59: 3291-3296.
    • (1991) Infect. Immun. , vol.59 , pp. 3291-3296
    • Anthony, L.S.D.1    Burke, R.D.2    Nano, F.E.3
  • 5
    • 0026550652 scopus 로고
    • Growth inhibition of Francisella tularensis live vaccine strain by IFN-gamma-activated macrophages is mediated by reactive nitrogen intermediates derived from 1-arginine metabolism
    • Anthony, L.S.D., Morrissey, P.J., and Nano, F.E. (1992a) Growth inhibition of Francisella tularensis live vaccine strain by IFN-gamma-activated macrophages is mediated by reactive nitrogen intermediates derived from 1-arginine metabolism. J Immunol 148: 1829-1834.
    • (1992) J. Immunol. , vol.148 , pp. 1829-1834
    • Anthony, L.S.D.1    Morrissey, P.J.2    Nano, F.E.3
  • 6
    • 0026550652 scopus 로고
    • Growth inhibition of Francisella tularensis live vaccine strain by IFN-gamma-activated macrophages is mediated by reactive nitrogen intermediates derived from 1-arginine metabolism
    • Anthony, L.S.D., Morrissey, P.J., and Nano, F.E. (1992b) Growth inhibition of Francisella tularensis live vaccine strain by IFN-gamma-activated macrophages is mediated by reactive nitrogen intermediates derived from 1-arginine metabolism. J Immunol 148: 1829-1834.
    • (1992) J. Immunol. , vol.148 , pp. 1829-1834
    • Anthony, L.S.D.1    Morrissey, P.J.2    Nano, F.E.3
  • 7
    • 0023000775 scopus 로고
    • Interferon-gamma-activated human monocytes inhibit the intracellular multiplication of Legionella pneumophila
    • Bhardwaj, N., Nash, T.W., and Horwitz, M.A. (1986) Interferon-gamma-activated human monocytes inhibit the intracellular multiplication of Legionella pneumophila. J Immunol 137: 2662-2669.
    • (1986) J. Immunol. , vol.137 , pp. 2662-2669
    • Bhardwaj, N.1    Nash, T.W.2    Horwitz, M.A.3
  • 8
    • 0024555386 scopus 로고
    • Interferon gamma-activated human monocytes downregulate transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of iron
    • Byrd, T.F., and Horwitz, M.A. (1989) Interferon gamma-activated human monocytes downregulate transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of iron. J Clin Invest 83: 1457-1465.
    • (1989) J. Clin. Invest. , vol.83 , pp. 1457-1465
    • Byrd, T.F.1    Horwitz, M.A.2
  • 9
    • 0024399957 scopus 로고
    • Interferon-induced indoleamine 2,3-dioxygenase activity inhibits Chlamydia psittaci replication in human macrophages
    • Carlin, J.M., Borden, E.C., and Byrne, G.I. (1989) Interferon-induced indoleamine 2,3-dioxygenase activity inhibits Chlamydia psittaci replication in human macrophages. J Interferon Res 9: 329-337.
    • (1989) J. Interferon Res. , vol.9 , pp. 329-337
    • Carlin, J.M.1    Borden, E.C.2    Byrne, G.I.3
  • 10
    • 0036227575 scopus 로고    scopus 로고
    • Tularemia and Q fever
    • Choi, E. (2002) Tularemia and Q fever. Med Clin North Am 86: 393-416.
    • (2002) Med. Clin. North Am. , vol.86 , pp. 393-416
    • Choi, E.1
  • 11
    • 2542552050 scopus 로고    scopus 로고
    • Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages
    • Clemens, D.L., Lee, B.Y., and Horwitz, M.A. (2004) Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages. Infect Immun 72: 3204-3217.
    • (2004) Infect. Immun. , vol.72 , pp. 3204-3217
    • Clemens, D.L.1    Lee, B.Y.2    Horwitz, M.A.3
  • 12
    • 0036353165 scopus 로고    scopus 로고
    • Different host defences are required to protect mice from primary systemic vs. pulmonary infection with the facultative intracellular bacterial pathogen, Francisella tularensis LVS
    • Conlan, J.W., KuoLee, R., Shen, H., and Webb, A. (2002) Different host defences are required to protect mice from primary systemic vs. pulmonary infection with the facultative intracellular bacterial pathogen, Francisella tularensis LVS. Microb Pathog 32: 127-134.
    • (2002) Microb. Pathog. , vol.32 , pp. 127-134
    • Conlan, J.W.1    KuoLee, R.2    Shen, H.3    Webb, A.4
  • 13
    • 0042624851 scopus 로고    scopus 로고
    • Multiple T cell subsets control Francisella tularensis LVS intracellular growth without stimulation through macrophage interferon gamma receptors
    • Cowley, S.C., and Elkins, K.L. (2003) Multiple T cell subsets control Francisella tularensis LVS intracellular growth without stimulation through macrophage interferon gamma receptors. J Exp Med 198: 379-389.
    • (2003) J. Exp. Med. , vol.198 , pp. 379-389
    • Cowley, S.C.1    Elkins, K.L.2
  • 14
    • 0031159107 scopus 로고    scopus 로고
    • Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice
    • Dai, W.J., Bartens, W., Kohler, G., Hufnagel, M., Kopf, M., and Brombacher, F. (1997) Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice. J Immunol 158: 5297-5304.
    • (1997) J. Immunol. , vol.158 , pp. 5297-5304
    • Dai, W.J.1    Bartens, W.2    Kohler, G.3    Hufnagel, M.4    Kopf, M.5    Brombacher, F.6
  • 16
    • 0033790751 scopus 로고    scopus 로고
    • Subversion of a young phagosome: The survival strategies of intracellular pathogens
    • Duclos, S., and Desjardins, M. (2000) Subversion of a young phagosome: the survival strategies of intracellular pathogens. Cell Microbiol 2: 365-377.
    • (2000) Cell Microbiol. , vol.2 , pp. 365-377
    • Duclos, S.1    Desjardins, M.2
  • 17
    • 0027534516 scopus 로고
    • T-cell-independent resistance to infection and generation of immunity to Francisella tularensis
    • Elkins, K.L., Rhinehart-Jones, T., Nacy, C.A., Winegar, R.K., and Fortier, A.H. (1993) T-cell-independent resistance to infection and generation of immunity to Francisella tularensis. Infect Immun 61: 823-829.
    • (1993) Infect. Immun. , vol.61 , pp. 823-829
    • Elkins, K.L.1    Rhinehart-Jones, T.2    Nacy, C.A.3    Winegar, R.K.4    Fortier, A.H.5
  • 18
    • 0030055895 scopus 로고    scopus 로고
    • Minimal requirements for murine resistance to infection with Francisella tularensis LVS
    • Elkins, K.L., Rhinehart-Jones, T.R., Culkin, S.J., Yee, D., and Winegar, R.K. (1996) Minimal requirements for murine resistance to infection with Francisella tularensis LVS. Infect Immun 64: 3288-3293.
    • (1996) Infect. Immun. , vol.64 , pp. 3288-3293
    • Elkins, K.L.1    Rhinehart-Jones, T.R.2    Culkin, S.J.3    Yee, D.4    Winegar, R.K.5
  • 19
    • 0031842836 scopus 로고    scopus 로고
    • Nonspecific early protective immunity in Francisella and Listeria infections can be dependent on lymphocytes
    • Elkins, K.L., MacIntyre, A.T., and Rhinehart-Jones, T.R. (1998) Nonspecific early protective immunity in Francisella and Listeria infections can be dependent on lymphocytes. Infect Immun 66: 3467-3469.
    • (1998) Infect. Immun. , vol.66 , pp. 3467-3469
    • Elkins, K.L.1    MacIntyre, A.T.2    Rhinehart-Jones, T.R.3
  • 20
    • 0037297290 scopus 로고    scopus 로고
    • Innate and adaptive immune responses to an intracellular bacterium, Francisella tularensis live vaccine strain
    • Elkins, K.L., Cowley, S.C., and Bosio, C.M. (2003) Innate and adaptive immune responses to an intracellular bacterium, Francisella tularensis live vaccine strain. Microbes Infect 5: 135-142.
    • (2003) Microbes. Infect. , vol.5 , pp. 135-142
    • Elkins, K.L.1    Cowley, S.C.2    Bosio, C.M.3
  • 22
    • 0025253004 scopus 로고
    • Identification of Francisella species and discrimination of type A and type B strains of F. tularensis by 16S rRNA analysis
    • Forsman, M., Sandstrom, G., and Jaurin, B. (1990) Identification of Francisella species and discrimination of type A and type B strains of F. tularensis by 16S rRNA analysis. Appl Environ Microbiol 56: 949-955.
    • (1990) Appl. Environ. Microbiol. , vol.56 , pp. 949-955
    • Forsman, M.1    Sandstrom, G.2    Jaurin, B.3
  • 23
    • 0027954534 scopus 로고
    • Analysis of 16S ribosomal DNA sequences of Francisella strains and utilization for determination of the phylogeny of the genus and for identification of strains by PCR
    • Forsman, M., Sandström, G., and Sjöstedt, A. (1994) Analysis of 16S ribosomal DNA sequences of Francisella strains and utilization for determination of the phylogeny of the genus and for identification of strains by PCR. Int J System Bacteriol 44: 38-46.
    • (1994) Int. J. System Bacteriol. , vol.44 , pp. 38-46
    • Forsman, M.1    Sandström, G.2    Sjöstedt, A.3
  • 24
    • 0026520203 scopus 로고
    • Activation of macrophages for destruction of Francisella tularensis: Identification of cytokines, effector cells, and effector molecules
    • Fortier, A.H., Polsinelli, T., Green, S.J., and Nacy, C.A. (1992) Activation of macrophages for destruction of Francisella tularensis: identification of cytokines, effector cells, and effector molecules. Infect Immun 60: 817-825.
    • (1992) Infect. Immun. , vol.60 , pp. 817-825
    • Fortier, A.H.1    Polsinelli, T.2    Green, S.J.3    Nacy, C.A.4
  • 25
    • 0000669855 scopus 로고
    • Tularemia
    • Francis, E. (1925) Tularemia. JAMA 84: 1243-1250.
    • (1925) JAMA , vol.84 , pp. 1243-1250
    • Francis, E.1
  • 26
    • 0035817635 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest
    • Fratti, R.A., Backer, J.M., Gruenberg, J., Corvera, S., and Deretic, V. (2001) Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest. J Cell Biol 154: 631-644.
    • (2001) J. Cell Biol. , vol.154 , pp. 631-644
    • Fratti, R.A.1    Backer, J.M.2    Gruenberg, J.3    Corvera, S.4    Deretic, V.5
  • 27
    • 0344766146 scopus 로고    scopus 로고
    • Apoptosis in macrophages and alveolar epithelial cells during early stages of infection by Legionella pneumophila and its role in cytopathogenicity
    • Gao, L.-Y., and Abu Kwaik, Y. (1999) Apoptosis in macrophages and alveolar epithelial cells during early stages of infection by Legionella pneumophila and its role in cytopathogenicity. Infect Immun 67: 862-870.
    • (1999) Infect. Immun. , vol.67 , pp. 862-870
    • Gao, L.-Y.1    Abu Kwaik, Y.2
  • 28
    • 0032708119 scopus 로고    scopus 로고
    • Heterogeneity in intracellular replication and cytopathogenicity of Legionella pneumophila and Legionella micdadei in mammalian and protozoan cells
    • Gao, L.-Y., Susa, M., Ticac, B., and Abu Kwaik, Y. (1999) Heterogeneity in intracellular replication and cytopathogenicity of Legionella pneumophila and Legionella micdadei in mammalian and protozoan cells. Microb Pathogen 27: 273-287.
    • (1999) Microb. Pathogen. , vol.27 , pp. 273-287
    • Gao, L.-Y.1    Susa, M.2    Ticac, B.3    Abu Kwaik, Y.4
  • 29
    • 0028048245 scopus 로고
    • Inhibition of Legionella pneumophila growth by gamma interferon in permissive A/J mouse macrophages: Role of reactive oxygen species, nitric oxide, tryptophan, and iron (III)
    • Gebran, S.J., Yamamoto, Y., Newton, C., Klein, T.W., and Friedman, H. (1994) Inhibition of Legionella pneumophila growth by gamma interferon in permissive A/J mouse macrophages: role of reactive oxygen species, nitric oxide, tryptophan, and iron (III). Infect Immun 62: 3197-3205.
    • (1994) Infect. Immun. , vol.62 , pp. 3197-3205
    • Gebran, S.J.1    Yamamoto, Y.2    Newton, C.3    Klein, T.W.4    Friedman, H.5
  • 31
    • 0027511113 scopus 로고
    • Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from 1-arginine and protection against Francisella tularensis infection in Mycobacterium bovis BCG-treated mice
    • Green, S.J., Nacy, C.A., Schreiber, R.D., Granger, D.L., Crawford, R.M., Meltzer, M.S., and Fortier, A.H. (1993) Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from 1-arginine and protection against Francisella tularensis infection in Mycobacterium bovis BCG-treated mice. Infect Immun 61: 689-698.
    • (1993) Infect. Immun. , vol.61 , pp. 689-698
    • Green, S.J.1    Nacy, C.A.2    Schreiber, R.D.3    Granger, D.L.4    Crawford, R.M.5    Meltzer, M.S.6    Fortier, A.H.7
  • 32
    • 0033980383 scopus 로고    scopus 로고
    • Characterization of a macrophage-specific infectivity locus (milA) of Legionella pneumophila
    • Harb, O.S., and Abu Kwaik, Y. (2000) Characterization of a macrophage-specific infectivity locus (milA) of Legionella pneumophila. Infect Immun 68: 368-376.
    • (2000) Infect. Immun. , vol.68 , pp. 368-376
    • Harb, O.S.1    Abu Kwaik, Y.2
  • 33
    • 0037989109 scopus 로고    scopus 로고
    • Francisella novicida LPS has greater immunobiological activity in mice than F. tularensis LPS, and contributes to F. novicida murine pathogenesis
    • Kieffer, T.L., Cowley, S., Nano, F.E., and Elkins, K.L. (2003) Francisella novicida LPS has greater immunobiological activity in mice than F. tularensis LPS, and contributes to F. novicida murine pathogenesis. Microbes Infect 5: 397-403.
    • (2003) Microbes. Infect. , vol.5 , pp. 397-403
    • Kieffer, T.L.1    Cowley, S.2    Nano, F.E.3    Elkins, K.L.4
  • 34
    • 0026035244 scopus 로고
    • Interferon-gamma induced resistance to Legionella pneumophila in susceptible A/J mouse macrophages
    • Klein, T.W., Yamamoto, Y., Brown, H.K., and Friedman, H. (1991) Interferon-gamma induced resistance to Legionella pneumophila in susceptible A/J mouse macrophages. J Leukoc Biol 49: 98-103.
    • (1991) J. Leukoc. Biol. , vol.49 , pp. 98-103
    • Klein, T.W.1    Yamamoto, Y.2    Brown, H.K.3    Friedman, H.4
  • 35
    • 0037970825 scopus 로고    scopus 로고
    • Francisella strains express hemolysins of distinct characteristics
    • Lai, X.H., Wang, S.Y., Edebro, H., and Sjostedt, A. (2003) Francisella strains express hemolysins of distinct characteristics. FEMS Microbiol Lett 224: 91-95.
    • (2003) FEMS Microbiol. Lett. , vol.224 , pp. 91-95
    • Lai, X.H.1    Wang, S.Y.2    Edebro, H.3    Sjostedt, A.4
  • 36
    • 1642447175 scopus 로고    scopus 로고
    • MgIA regulates transcription of virulence factors necessary for Francisella tularensis intraamoebae and intramacrophage survival
    • Lauriano, C.M., Barker, J.R., Yoon, S.S., Nano, F.E., Arulanandam, B.P., Hassett, D.J., and Klose, K.E. (2004) MgIA regulates transcription of virulence factors necessary for Francisella tularensis intraamoebae and intramacrophage survival. Proc Natl Acad Sci USA 101: 4246-4249.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4246-4249
    • Lauriano, C.M.1    Barker, J.R.2    Yoon, S.S.3    Nano, F.E.4    Arulanandam, B.P.5    Hassett, D.J.6    Klose, K.E.7
  • 37
    • 0026571327 scopus 로고
    • In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodies
    • Leiby, D.A., Fortier, A.H., Crawford, R.M., Schreiber, R.D., and Nacy, C.A. (1992) In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodies. Infect Immun 60: 84-89.
    • (1992) Infect. Immun. , vol.60 , pp. 84-89
    • Leiby, D.A.1    Fortier, A.H.2    Crawford, R.M.3    Schreiber, R.D.4    Nacy, C.A.5
  • 38
    • 9244229561 scopus 로고    scopus 로고
    • Distinct roles of reactive nitrogen and oxygen species to control infection with the facultative intracellular bacterium Francisella tularensis
    • Lindgren, H., Stenmark, S., Chen, W., Tarnvik, A., and Sjostedt, A. (2004) Distinct roles of reactive nitrogen and oxygen species to control infection with the facultative intracellular bacterium Francisella tularensis. Infect Immun 72: 7172-7182.
    • (2004) Infect. Immun. , vol.72 , pp. 7172-7182
    • Lindgren, H.1    Stenmark, S.2    Chen, W.3    Tarnvik, A.4    Sjostedt, A.5
  • 39
    • 0242485924 scopus 로고    scopus 로고
    • The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells
    • Meresse, S., Steele-Mortimer, O., Finlay, B.B., and Gorvel, J. P. (1999a) The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells. EMBO J 18: 4394-4403.
    • (1999) EMBO J. , vol.18 , pp. 4394-4403
    • Meresse, S.1    Steele-Mortimer, O.2    Finlay, B.B.3    Gorvel, J.P.4
  • 41
    • 3042687722 scopus 로고    scopus 로고
    • Disruption of the phagosomal membrane and egress of Legionella pneumophila into the cytoplasm during late stages of the intracellular infection of macrophages and Acanthamoeba polyphaga
    • Molmeret, M., Bitar, D., Han, L., and Abu Kwaik, Y. (2004) Disruption of the phagosomal membrane and egress of Legionella pneumophila into the cytoplasm during late stages of the intracellular infection of macrophages and Acanthamoeba polyphaga. Infect Immun 72: 4040-4051.
    • (2004) Infect. Immun. , vol.72 , pp. 4040-4051
    • Molmeret, M.1    Bitar, D.2    Han, L.3    Abu Kwaik, Y.4
  • 42
    • 2942609903 scopus 로고
    • The ecology of tularaemia
    • Morner, T. (1992) The ecology of tularaemia. Rev Sci Tech 11: 1123-1130.
    • (1992) Rev. Sci. Tech. , vol.11 , pp. 1123-1130
    • Morner, T.1
  • 43
    • 0035968220 scopus 로고    scopus 로고
    • SopE acts as an Rab5-specific nucleotide exchange factor and recruits non-prenylated Rab5 on Salmonella-containing phagosomes to promote fusion with early endosomes
    • Mukherjee, K., Parashuraman, S., Raje, M., and Mukhopadhyay, A. (2001) SopE acts as an Rab5-specific nucleotide exchange factor and recruits non-prenylated Rab5 on Salmonella-containing phagosomes to promote fusion with early endosomes. J Biol Chem 276: 23607-23615.
    • (2001) J. Biol. Chem. , vol.276 , pp. 23607-23615
    • Mukherjee, K.1    Parashuraman, S.2    Raje, M.3    Mukhopadhyay, A.4
  • 44
    • 4544341163 scopus 로고    scopus 로고
    • A Francissella tularensis pathogenicity island required for intramacrophage growth
    • Nano, F.E., Zhang, N., Cowley, S.C., Klose, K.E., Cheung, K.K., Roberts, M.J., et al. (2004) A Francissella tularensis pathogenicity island required for intramacrophage growth. J Bacteriol 186: 6430-6436.
    • (2004) J. Bacteriol. , vol.186 , pp. 6430-6436
    • Nano, F.E.1    Zhang, N.2    Cowley, S.C.3    Klose, K.E.4    Cheung, K.K.5    Roberts, M.J.6
  • 45
    • 0021169749 scopus 로고
    • Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone
    • Nash, T.W., Libby, D.M., and Horwitz, M.A. (1984) Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone. J Clin Invest 74: 771-782.
    • (1984) J. Clin. Invest. , vol.74 , pp. 771-782
    • Nash, T.W.1    Libby, D.M.2    Horwitz, M.A.3
  • 46
    • 0023875737 scopus 로고
    • IFN-gamma-activated human alveolar macrophages inhibit the intracellular multiplication of Legionella pneumophila
    • Nash, T.W., Libby, D.M., and Horwitz, M.A. (1988) IFN-gamma-activated human alveolar macrophages inhibit the intracellular multiplication of Legionella pneumophila. J Immunol 140: 3978-3981.
    • (1988) J. Immunol. , vol.140 , pp. 3978-3981
    • Nash, T.W.1    Libby, D.M.2    Horwitz, M.A.3
  • 47
    • 9644307958 scopus 로고    scopus 로고
    • Intranasal interleukin-12 treatment promotes antimicrobial clearance and survival in pulmonary Francisella tularensis subsp. novicida infection
    • Pammit, M.A., Budhavarapu, V.N., Raulie, E.K., Klose, K.E., Teale, J.M., and Arulanandam, B.P. (2004) Intranasal interleukin-12 treatment promotes antimicrobial clearance and survival in pulmonary Francisella tularensis subsp. novicida infection. Antimicrob Agents Chemother 48: 4513-4519.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 4513-4519
    • Pammit, M.A.1    Budhavarapu, V.N.2    Raulie, E.K.3    Klose, K.E.4    Teale, J.M.5    Arulanandam, B.P.6
  • 48
    • 0035081919 scopus 로고    scopus 로고
    • HtrA homologue of Legionella pneumophila: An indispensable element for intracellular infection of mammalian but not protozoan cells
    • Pedersen, L.L., Radulic, M., Doric, M., and Abu Kwaik, Y. (2001) HtrA homologue of Legionella pneumophila: an indispensable element for intracellular infection of mammalian but not protozoan cells. Infect Immun 69: 2569-2579.
    • (2001) Infect. Immun. , vol.69 , pp. 2569-2579
    • Pedersen, L.L.1    Radulic, M.2    Doric, M.3    Abu Kwaik, Y.4
  • 49
    • 0028341477 scopus 로고
    • Nitric oxide-independent killing of Francisella tularensis by IFN-gamma-stimulated murine alveolar macrophages
    • Polsinelli, T., Meltzer, M.S., and Fortier, A.H. (1994) Nitric oxide-independent killing of Francisella tularensis by IFN-gamma-stimulated murine alveolar macrophages. J Immunol 153: 1238-1245.
    • (1994) J. Immunol. , vol.153 , pp. 1238-1245
    • Polsinelli, T.1    Meltzer, M.S.2    Fortier, A.H.3
  • 50
    • 21344468870 scopus 로고    scopus 로고
    • The Francisella tularensis pathogencity island protein IgIC and its regulator MgIA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm
    • Santic, M., Molmeret, M., Klose, K.E., Jones, S., and Abu Kwaik, Y. (2005a) The Francisella tularensis pathogencity island protein IgIC and its regulator MgIA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm. Cell Microbiol 7: 969-979.
    • (2005) Cell Microbiol. , vol.7 , pp. 969-979
    • Santic, M.1    Molmeret, M.2    Klose, K.E.3    Jones, S.4    Abu Kwaik, Y.5
  • 51
    • 17644420042 scopus 로고    scopus 로고
    • Maturation of the Legionella pneumophila-containing phagosome into a phagolysosome within IFN-gamma activated macrophages
    • (in press)
    • Santic, M., Molmeret, M., and Abu Kwaik, Y. (2005b) Maturation of the Legionella pneumophila-containing phagosome into a phagolysosome within IFN-gamma activated macrophages. Infect Immun (in press).
    • (2005) Infect. Immun.
    • Santic, M.1    Molmeret, M.2    Abu Kwaik, Y.3
  • 52
    • 0031914958 scopus 로고    scopus 로고
    • Cytokine activation leads to acidification and increases maturation of Mycobacterium avium-containing phagosomes in murine macrophages
    • Schaible, U.E., Sturgill-Koszycki, S., Schlesinger, P.H., and Russell, D.G. (1998) Cytokine activation leads to acidification and increases maturation of Mycobacterium avium-containing phagosomes in murine macrophages. J Immunol 160: 1290-1296.
    • (1998) J. Immunol. , vol.160 , pp. 1290-1296
    • Schaible, U.E.1    Sturgill-Koszycki, S.2    Schlesinger, P.H.3    Russell, D.G.4
  • 53
    • 0037329843 scopus 로고    scopus 로고
    • Virulence determinants and protective antigens of Francisella tularensis
    • Sjostedt, A. (2003) Virulence determinants and protective antigens of Francisella tularensis. Curr Opin Microbiol 6: 66-71.
    • (2003) Curr. Opin. Microbiol. , vol.6 , pp. 66-71
    • Sjostedt, A.1
  • 54
    • 0030481130 scopus 로고    scopus 로고
    • Mycobacterium-containing phagosomes are accessible to early endosomes and reflect a transitional state in normal phagosome biogenesis
    • Sturgill-Koszycki, S., Schaible, U.E., and Russell, D.G. (1996) Mycobacterium-containing phagosomes are accessible to early endosomes and reflect a transitional state in normal phagosome biogenesis. EMBO J 15: 6960-6968.
    • (1996) EMBO J. , vol.15 , pp. 6960-6968
    • Sturgill-Koszycki, S.1    Schaible, U.E.2    Russell, D.G.3
  • 55
    • 0037342407 scopus 로고    scopus 로고
    • Will the enigma of Francisella tularensis virulence soon be solved?
    • Titball, R.W., Johansson, A., and Forsman, M. (2003) Will the enigma of Francisella tularensis virulence soon be solved? Trends Microbiol 11: 118-123.
    • (2003) Trends Microbiol. , vol.11 , pp. 118-123
    • Titball, R.W.1    Johansson, A.2    Forsman, M.3
  • 56
    • 9444231112 scopus 로고    scopus 로고
    • Francisella tularensis: An overview
    • Titball, R., and Sjosted, A. (2003) Francisella tularensis: an overview. ASM News 69: 558-563.
    • (2003) ASM News , vol.69 , pp. 558-563
    • Titball, R.1    Sjosted, A.2
  • 57
    • 1342344959 scopus 로고    scopus 로고
    • Increases in c-Jun N-terminal kinase/stress-activated protein kinase and p38 activity in monocyte-derived macrophages following the uptake of Legionella pneumophila
    • Welsh, C.T., Summersgill, J.T., and Miller, R.D. (2004) Increases in c-Jun N-terminal kinase/stress-activated protein kinase and p38 activity in monocyte-derived macrophages following the uptake of Legionella pneumophila. Infect Immun 72: 1512-1518.
    • (2004) Infect. Immun. , vol.72 , pp. 1512-1518
    • Welsh, C.T.1    Summersgill, J.T.2    Miller, R.D.3
  • 58
    • 0034279791 scopus 로고    scopus 로고
    • Biogenesis of the sorting endosome: The role of Rab5
    • Woodman, P.G. (2000) Biogenesis of the sorting endosome: the role of Rab5. Traffic 1: 695-701.
    • (2000) Traffic , vol.1 , pp. 695-701
    • Woodman, P.G.1


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