Minimal requirements for murine resistance to infection with Francisella tularensis LVS

Infection and Immunity

Volumn 64, Issue 8, 1996, Pages 3288-3293

  Elkins, Karen L ^a,c   Rhinehart Jones, Tonya R ^a   Culkin, Sarah J ^a   Yee, Daphne ^a   Winegar, Robert K ^b  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE ANTIBODY; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; RB 68C5; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL TRANSFER; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; FATALITY; FRANCISELLA TULARENSIS; GRAM NEGATIVE INFECTION; INFECTION RESISTANCE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE;

EID: 0030055895     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.8.3288-3293.1996     Document Type: Article

References (46)

1. Anthony, L. S. D., E. Ghadirian, F. P. Nestel, and P. A. L. Kongshavn. 1989. The requirement for gamma interferon in resistance of mice to experimental tularemia. Microb. Pathog. 7:421-428.
2. Autenrieth, I. B., V. Vogel, S. Preger, B. Heymer, and J. Heesemann. 1993. Experimental Yersinia entercolitica infection in euthymic and T-cell-deficient athymic nude C57B1/6 mice: comparison of time course, histomorphology, and immune response. Infect. Immun. 61:2585-2595.
3. Baker, C. N., D. G. Hollis, and C. Thornsberry. 1985. Anti-microbial susceptibility testing of Francisella tularensis with a modified Mueller-Hinton broth. J. Clin. Microbiol. 22:212-215.
4. Bancroft, G. J., R. D. Schreiber, G. C. Bosma, M. J. Bosma, and E. R. Unanue. 1987. A T-cell-independent mechanism of macrophage activation by interferon-gamma. J. Immunol. 139:1104-1107.
5. Bancroft, G. J., K. C. F. Sheehan, R. D. Schreiber, and E. R. Unanue. 1989. Tumor necrosis factor is involved in the T-cell-independent pathway of macrophage activation in scid mice. J. Immunol. 143:127-130.
6. Belosevic, M., D. S. Finbloom, P. H. Van der meide, M. V. Slayer, and C. A. Nacy. 1989. Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major. J. Immunol. 143:266-274.
7. Cassatella, M. A. 1995. The production of cytokines by polymorphonuclear neutrophils. Immunol. Today 16:21-26.
8. Clark, E. A., and J. A. Ledbetter. 1994. How B and T cells talk to each other. Nature (London) 367:425-428.
9. Conlan, J. W., and R. J. North. 1991. Neutrophil-mediated dissolution of infected host cells as a defense strategy against a facultative intracellular bacterium. J. Exp. Med. 174:741-744.
10. Conlan, J. W., and R. J. North. 1994. Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody. J. Exp. Med. 179:259-268.
11. + T-cell-dependent and -independent host defense mechanisms can operate to control and resolve primary and secondary Francisella tularensis LVS infection in mice. Infect. Immun. 62:5603-5607.
12. + cells in resistance to primary and secondary infection, delayed-type hypersensitivity and adoptive transfer of resistance. Immunology 71:107-112.
13. Elkins, K. L., D. A. Leiby, R. K. Winegar, C. A. Nacy, and A. H. Fortier. 1992. Rapid generation of specific protective immunity to Francisella tularensis. Infect. Immun. 60:4571-4577.
14. Elkins, K. L., T. Rhinehart-Jones, C. A. Nacy, R. K. Winegar, and A. H. Fortier. 1993. T-cell-independent resistance to infection and generation of immunity to Francisella tularensis. Infect. Immun. 61:823-829.
15. Elkins, K. L., R. K. Winegar, C. A. Nacy, and A. H. Fortier. 1992. Introduction of Francisella tularensis at skin sites induces resistance to infection and generation of protective immunity. Microb. Pathog. 13:417-421.
16. Flynn, J. L., J. Chan, K. J. Triebold, D. Dalton, T. A. Stewart, and B. R. Bloom. 1993. An essential role for interferon γ in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178:2249-2254.
17. Fortier, A. H., M. V. Slayter, R. Ziemba, M. S. Meltzer, and C. A. Nacy. 1991. Live vaccine strain of Francisella tularensis: infection and immunity in mice. Infect. Immun. 59:2922-2928.
18. Harly, J. T., R. D. Schreiber, and M. J. Bevan. 1992. CD8 T cells can protect against an intracellular bacterium in an interferon gamma-independent fashion. Proc. Natl. Acad. Sci. USA 89:11612-11616.
19. Huang, S., W. Hendricks, A. Althage, S. Hemmi, H. Bluethmann, R. Kamiho, J. Vilcek, R. M. Zinkernagel, and M. Aguet. 1993. Immune response in mice that lack the interferon-γ receptor. Science 259:1742-1745.
20. Hunter, C. A., J. S. Ahrams, M. H. Beaman, and J. S. Remington. 1993. Cytokine mRNA in the central nervous system of SCID mice infected with Toxoplasma gondii: importance of T-cell-independent regulation of resistance to T. gondii. Infect. Immun. 61:4038-4044.
21. + T cells. J. Exp. Med. 176:581-586.
22. Kaufmann, S. H. E. 1989. In vitro analysis of the cellular mechanisms involved in immunity to tuberculosis. Rev. Infect. Dis. 11(Suppl. 2):S448-S454.
23. Ladel, C. H., S. Daugelat, and S. H. E. Kaufmann. 1995. Immune response to Mycobacterium bovis bacille Calmette Guérin infection in major histocompatibility complex class I- and II-deficient knock-out mice: contribution of CD4 and CD8 T cells to acquired resistance. Eur. J. Immunol. 25:377-384.
24. Ladel, C. H., I. E. A. Flesch, J. Arnoldi, and S. H. E. Kaufmann. 1994. Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on Listeria monocytogenes infection. J. Immunol. 153:3116-3122.
25. Laskay, T., M. Röllinghoff, and W. Solbach. 1993. Natural killer cells participate in the early defense against Leishmania major infection in mice. Eur. J. Immunol. 23:2237-2241.
26. Leiby, D. A., A. H. Fortier, R. M. Crawford, R. D. Schreiber, and C. A. Nacy. 1992. In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodies. Infect. Immun. 60:84-89.
27. Lennette, E. H. 1964. General principles underlying laboratory diagnosis of virus and rickettsial infections, p. 45. In E. H. Lennette and N. J. Schmidt (ed.), Diagnostic procedures of virus and rickettsial disease. American Public Health Association, New York.
28. Mombaerts, P., J. Arnoldi, F. Russ, S. Tonegawa, and S. H. E. Kaufmann. 1993. Different roles of αβ and γδ T cells in immunity against an intracellular bacterial pathogen. Nature (London) 365:53-56.
29. Nauciel, C., and F. Espinasse-Maes. 1992. Role of gamma interferon and tumor necrosis factor alpha in resistance to Salmonella typhimurium infection. Infect. Immun. 60:450-454.
30. O'Brien, A. D., and E. S. Metcalf. 1982. Control of early Salmonella typhimurium growth in innately Salmonella-resistant mice does not require functional T cells. J. Immunol. 129:1349-1351.
31. Orme, I. M. 1987. The kinetics of emergence and loss of mediatory T lymphocytes acquired in response to infection with Mycobacterium tuberculosis. J. Immunol. 138:293-298.
32. Pfeffer, K., T. Matsuyama, T. Kundig, A. Wakeham, K. Kishihara, A. Shahinian, K. Wiegmann, P. S. Ohashi, M. Kronke, and T. W. Mak. 1993. Mice deficient for the 55kd tumor necrosis factor receptor arc resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73:457-467.
33. Portnoy, D. A. 1992. Innate immunity to a facultative intracellular bacterial pathogen. Curr. Opin. Immunol. 4:20-24.
34. Reimann, J., A. Rudolphi, and M. H. Claesson. 1991. Selective reconstitution of T lymphocyte subsets in scid mice. Immunol. Rev. 124:75-95.
35. Rhinehart-Jones, T. R., A. H. Fortier, and K. L. Elkins. 1994. Transfer of immunity against lethal murine Francisella infection by specific antibody depends on host gamma interferon and T cells. Infect. Immun. 62:3129-3137.
36. Roberts, A. D., D. J. Ordway, and I. M. Orme. 1993. Listeria monocytogenes infection in β2 microglobulin-deficient mice. Infect. Immun. 61:1113-1116.
37. Rothe, J., W. Lesslauer, H. Lotscher, V. Lang, P. Keobel, F. Kontgen, A. Althage, R. Zinkernagel, M. Steinmetz, and H. Bluethmann. 1993. Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listens monocytogenes. Nature (London) 364:798-802.
38. Sandstrom, G., S. Lofgren, and A. Tarnvik. 1988. A capsule-deficient mutant of Francisella tularensis LVS exhibits enhanced sensitivity to killing by serum but diminished sensitivity to killing by polymorphonuclear leukocytes. Infect. Immun. 56:1194-1202.
39. Schreiber, R. D., L. J. Hicks, A. Celada, N. A. Buchmeier, and P. W. Gray. 1985. Monoclonal antibodies to murine gamma-interferon which differentially modulate macrophage activation and anti-viral activity. J. Immunol. 134:1609-1618.
40. Sheehan, K. C. F., N. H. Ruddle, and R. D. Schrieber. 1989. Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors. J. Immunol. 142:3884-3893.
41. Sjöstedt, A., J. W. Conlan, and R. J. North. 1914. Neutrophils are critical for host defense against primary infection with the facultative intracellular bacterium Francisella tularensis in mice and participate in defense against reinfection. Infect. Immun. 62:2779-2783.
42. Swartz, M. N., and A. N. Weinberg. 1987. Miscellaneous bacterial infections with cutaneous manifestations, p. 2136-2151. In T. B. Fitzpatrick, A. Z. Eisen, K. Wolff, I. M. Freedberg, and K. F. Austen (eds.), Dermatology in general medicine, 3rd ed. McGraw-Hill Book Co., New York.
43. Tarnvik, A. 1989. Nature of protective immunity to Francisella tularensis. Rev. Infect. Dis. 11:440-451.
44. Tepper, R. I., R. L. Coffman, and P. Leder. 1992. An cosinophil-dependent mechanism for the antitumor effect of interleukin-4. Science 257:548-551.
45. Tripp, C. S., S. F. Wolf, and E. R. Unanue. 1993. Interleukin 12 and tumor necrosis factor α are costimulators of interferon γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiological antagonist. Proc. Natl. Acad. Sci. USA 90:3725-3729.
46. Yee, D., T. R. Rhinehart-Jones, and K. L. Elkins. Submitted for publication.