Salmonella pathogenicity island 2-encoded type III secretion system mediates exclusion of NADPH oxidase assembly from the phagosomal membrane

Journal of Immunology

Volumn 166, Issue 9, 2001, Pages 5741-5748

  Gallois, A ^a   Klein, J R ^a   Allen, L A H ^a   Jones, B D ^a   Nauseef, W M ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LACTATE DEHYDROGENASE (CYTOCHROME); REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; VIRULENCE FACTOR;

ACIDIFICATION; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYSOSOME; PATHOGENICITY; PHAGOSOME; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SALMONELLA; SALMONELLA TYPHIMURIUM;

EID: 0035339862     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.9.5741     Document Type: Article

References (37)

1. Salmonellosis: Host immune responses and bacterial virulence determinants
2. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
3. Intraceliular replication is essential for the virulence of Salmonella typhimurium
4. Unravelling the mysteries of virulence gene regulation in Salmonella typhimurium
5. Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cells
6. Type III protein secretion systems in bacterial pathogens of animals and plants
7. Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria
8. Molecular basis of the interaction of Salmonella with the intestinal mucosa
9. Simultaneous identification of bacterial virulence genes by negative selection
10. Identification of a pathogenicity island required for Salmonella survival in host cells
11. Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages
12. Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival
13. Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase
14. 558: Identification of two juxtaposed extracellular domains
15. Topological mapping of neutrophil cytochrome b epitopes with phage-display libraries
16. phox with phagosomes in neutrophils from patients with X-linked chronic granulomatous disease
17. Functional analysis of ssaJ and the ssaK/U operon, 13 genes encoding components of the type III secretion apparatus of Salmonella pathogenicity island 2
18. Transcriptional organization and function of invasion genes within Salmonella enterica serovar Typhimurium pathogenicity island 1, including the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes
19. The Salmonella pathogenicity island 2-encoded proteins sseC and sseD are essential for virulence and are substrates of the type III secretion system
20. Activation of phospholipase D is tightly coupled to the phagocytosis of Mycobacterium tuberculosis or opsonized zymosan by human macrophages
21. Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes
22. NADPH oxidase activation and assembly during phagocytosis
23. Lack of enhanced oxygen consumption by polymorphonuclear leukocytes on phagocytosis of virulent Salmonella typhi
24. Diminished neutrophil oxidative metabolism after phagocytosis of virulent Salmonella typhi
25. The unique trafficking pattern of Salmonella typhimurium-containing phagosomes in murine macrophages is independent of the mechanism of bacterial entry
26. Live Salmonella modulate expression of Rah proteins to persist in a specialized compartment and escape transport to lysosomes
27. A Salmonella virulence protein that inhibits cellular trafficking
28. Proton conductance of the plasma membrane: Properties, regulation, and functional role
29. + conductance in NADPH oxidase-defective neutrophils
30. Electron currents generated by the human phagocyte NADPH oxidase
31. + conductance in eosinophils: Unique characteristics and absence in chronic granulomatous disease
32. + channel generated through alternative splicing of the NADPH oxidase homolog NOH-1
33. phox
34. Different subcellular localization of cytochrome b and the dormant NADPH-oxidase in neutrophils and macrophages: Effect on the production of reactive oxygen species during phagocytosis
35. Cytoskeleton-membrane interaction and the remodeling of the cell surface during phagocytosis and chemotaxis
36. Distribution of receptors and functions on cell surfaces: Quantitation of ligand-receptor mobility and a new model for the control of plasma membrane topography
37. Surface and cytoskeletal events regulating leukocyte membrane topography