Role of polyamines, their analogs and transglutaminases in biological and clinical perspectives

Amino Acids

Volumn 42, Issue 2-3, 2012, Pages 397-409

  Agostinelli, Enzo ^a  

^a Pasteur Institute   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AGMATINE; AMINE OXIDASE (COPPER CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING); ANTIMONY DERIVATIVE; ANTIZYME; ARGININE; BIOGENIC AMINE; ELONGATION FACTOR 2; INITIATION FACTOR 5A; JASMONIC ACID METHYL ESTER; MONOAMINE OXIDASE B INHIBITOR; N1,N11 DIETHYLNORSPERMINE; ORNITHINE; ORNITHINE DECARBOXYLASE; ORNITHINE DECARBOXYLASE INHIBITOR; OXIDOREDUCTASE; PERMEASE; POLYAMINE; POLYAMINE OXIDASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN LYSINE 6 OXIDASE; PUTRESCINE; REACTIVE OXYGEN METABOLITE; S ADENOSYLMETHIONINE; SPERMIDINE; SPERMIDINE SYNTHASE; SPERMINE; SPERMINE OXIDASE; TRYPANOTHIONE REDUCTASE; UNCLASSIFIED DRUG;

AUTOIMMUNE DISEASE; BIOCHEMISTRY; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CATARACT; CELIAC DISEASE; CELL CYCLE REGULATION; CELL DEATH; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CONFERENCE PAPER; DEGENERATIVE DISEASE; DIABETES MELLITUS; DISEASE ASSOCIATION; ENZYME SUBSTRATE; ENZYMOLOGY; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENETIC REGULATION; HEALTH HAZARD; HEART HYPERTROPHY; HELICOBACTER PYLORI; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RESPONSE; INFLAMMATION; LEISHMANIA; LIQUID CHROMATOGRAPHY; MALARIA; MALIGNANT NEOPLASTIC DISEASE; MEDICAL RESEARCH; MEMBRANE TRANSPORT; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OBESITY; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PANCREATITIS; PATHOGENESIS; PATHOPHYSIOLOGY; PEER REVIEW; PLANT GROWTH; PLANT STRESS; POLYAMINE METABOLISM; POLYAMINE SYNTHESIS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN INTERACTION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TEA; EDITORIAL; METABOLISM; PHYSIOLOGY;

BIOGENIC POLYAMINES; TRANSGLUTAMINASES;

EID: 84861703571     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-011-1129-2     Document Type: Conference Paper

References (155)

1. Agostinelli E, Arancia G, Dalla Vedova L, Belli F, Marra M, Salvi M, Toninello A (2004) The biological functions of polyamine oxidation products by amine oxidases: perspectives of clinical applications. Amino Acids 27:347-358 (Pubitemid 40110080)
2. Agostinelli E, Condello M, Molinari A, Tempera G, Viceconte N, Arancia G (2009) Cytotoxicity of spermine oxidation products to multidrug resistant melanoma cells (M14 ADR2): sensitization by MDL 72527, a lysosomotropic compound. Int J Oncol 35:485-498
3. Agostinelli E, Seiler N (2006) Non-irradiation-derived reactive oxygen species (ROS) and cancer: therapeutic implications. Amino Acids 31:341-355 (Pubitemid 44537062)
4. Agostinelli E, Belli F, Molinari A, Condello M, Palmigiani P, DallaVedova L, Marra M, Seiler N, Arancia G (2006) Toxicity of enzymatic oxidation products of spermine to human melanoma cells (M14): sensitization by heat and MDL 72527. Biochim Biophys Acta 1763:1040-1050 (Pubitemid 44466116)
5. Agostinelli E, Marques MPM, Calheiros R, Gil FPSC, Tempera G, Viceconte N, Battaglia V, Grancara S, Toninello A (2010a) Polyamines: fundamental characters in chemistry and biology. Amino Acids 38:393-403
6. Agostinelli E, Tempera G, Viceconte N, Saccoccio S, Battaglia V, Grancara S, Toninello A, Stevanato R (2010b) Potential anticancer application of polyamine oxidation products formed by amine oxidase: a new therapeutic approach. Amino Acids 38:353-368
7. Agostinelli E, Toninello A, Vianello F, Stevanato R (2011) Do mammalian amine oxidases and the mitochondrial polyamine transporter have similar protein structures? Amino Acids (in this issue). doi:10.1007/s00726-011-0988-x
8. Amendola R, Cervelli M, Fratini E, Polticelli F, Sallustio DE, Mariottini P (2009) Spermine metabolism and anticancer therapy. Current Cancer Drug Targets 9:118-130
9. Arancia G, Calcabrini A, Marra M, Crateri P, Artico M, Martone A, Martelli F, Agostinelli E (2004) Mitochondrial alterations induced by serum amine oxidase and spermine on human multidrug resistant tumor cells. Amino Acids 26:273-282 (Pubitemid 38829791)
10. Arisan ED, Ç oker A, Palavan-Ü nsal N (2011) Polyamine depletion enhances the roscovitine-induced apoptosis through the activation of mitochondria in HCT116 colon carcinoma cells. Amino Acids (in this issue). doi:10.1007/s00726-011-1040-x
11. Averill-Bates DA, Cherif A, Agostinelli E, Tanel A, Fortier G (2005) Anti-tumoral effect of native and immobilized bovine serum amine oxidase in a mouse melanoma model. Biochem Pharmacol 69:1693-1704 (Pubitemid 40780069)
12. Bachrach U (2004) Polyamines and cancer: minireview article. Amino Acids 4:307-309 (Pubitemid 39093131)
13. Bachrach U (2011) Concluding remarks. Amino Acids (in this issue). doi:10.1007/s00726-011-1022-z
14. Bachrach U, Wang YC, Tabib A (2001) Polyamines: new cues in cellular signal transduction. News Physiol Sci 16:106-109 (Pubitemid 33570296)
15. Baiocco P, Ilari A, Ceci P, Orsini S, Gramiccia M, Di Muccio T, Colotti G (2011) Inhibitory effect of silver nanoparticles on trypanothione reductase activity and Leishmania infantum proliferation. ACS Med Chem Lett 2:230-233
16. Bandino A, Battaglia V, Bravoco V, Busletta C, Compagnone A, Cravanzola C, Meli F, Agostinelli E, Parola M, Colombatto S (2011) Chronic exposure to agmatine results in the selection of agmatine-resistant hepatoma cells. Amino Acids (in this issue). doi:10.1007/s00726-011-0993-0
17. Battaglia V, Tibaldi E, Grancara S, Zonta F, Brunati AM, Martinis P, Bragadin M, Grillo MA, Tempera G, Agostinelli E, Toninello A (2011) Effect of peroxides on spermine transport in rat brain and liver mitochondria. Amino Acids (in this issue). doi:10.1007/ s00726-011-0990-3
18. Battaglia V, Grancara S, Mancon M, Cravanzola C, Colombatto S, Grillo MA, Tempera G, Agostinelli E, Toninello A (2010) Agmatine transport in brain mitochondria: a different mechanism from that in liver mitochondria. Amino Acids 38:423-430
19. Bonaiuto E, Minarini A, Tumiatti V, Milelli A, Lunelli M, Pegoraro M, Rizzoli V, Di Paolo ML (2011) Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. Amino Acids (in this issue). doi:10.1007/s00726-011-1006-z
20. Brückner H, Flassig S, Kirschbaum J (2011) Determination of biogenic amines in infusions of tea (Camellia sinensis) by HPLC after derivatization with 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl). Amino Acids (in this issue). doi:10.1007/s00726-011-1003-2
21. Büttner K, Hertel TC, Pietzsch M (2011) Increased thermostability of microbial transglutaminase by combination of several hot spots evolved by random and saturation mutagenesis. Amino Acids (in this issue). doi:10.1007/s00726-011-1015-y
22. Caccamo D, Currò M, Ferlazzo N, Condello S, Ientile R (2011) Monitoring of transglutaminase2 under different oxidative stress conditions. Amino Acids (in this issue). doi:10.1007/s00726-011-1018-8
23. Calcabrini A, Arancia G, Marra M, Crateri P, Befani O, Martone A, Agostinelli E (2002) Enzymatic oxidation products of spermine induce greater cytotoxic effects on human multidrug- resistant colon carcinoma cells (LoVo) than on their wild type counterparts. Int J Cancer 99:43-52 (Pubitemid 34273196)
24. Caputo I, Barone MV, Martucciello S, Lepretti M, Esposito C (2009) Tissue transglutaminase in celiac disease: role of autoantibodies. Amino Acids 36:693-699
25. Casero RA Jr, Pegg AE (2010) Polyamine catabolism and disease. Biochem J 421:323-338
26. Casero RA, Woster PM (2009) Recent advances in the development of polyamine analogues as antitumor agents. J Med Chem 52:4551-4573
27. Cecchi L, D'Amato G, Ayres JG, Galan C, Forastiere F, Forsberg B, Gerritsen J, Nunes C, Behrendt H, Akdis C, Dahl R, Annesi- Maesano I (2010) Projections of the effects of climate change on allergic asthma: the contribution of aerobiology. Allergy 65: 1073-1081
28. Cerrada-Gimenez M, Häkkinen MR, Vepsäläinen J, Auriola S, Alhonen L, Keinänen TA (2011) Polyamine flux analysis by determination of heavy isotope incorporation from 13C, 15Nenriched amino acids into polyamines by LC-MS/MS. Amino Acids (in this issue). doi:10.1007/s00726-011-1024-x
29. Cerrada-Gimenez M, Häyrinen J, Juutinen S, Reponen T, Jänne J, Alhonen L (2010) Proteomic analysis of livers from a transgenic mouse line with activated polyamine catabolism. Amino Acids 38:613-622
30. Cervelli M, Amendola R, Polticelli F, Mariottini P (2011) Spermine oxidase: ten years after. Amino Acids (in this issue). doi: 10.1007/s00726-011- 1014-z
31. Cetrullo S, Facchini A, Stanic I, Tantini B, Pignatti C, Caldarera CM, Flamigni F (2010) Difluoromethylornithine inhibits hypertrophic, pro-fibrotic and pro-apoptotic actions of aldosterone in cardiac cells. Amino Acids 38:525-531
32. Chaturvedi R, Asim M, Hoge S, Lewis ND, Singh K, Barry DP, de Sablet T, Piazuelo MB, Sarvaria AR, Cheng Y, Closs EI, Casero RA, Jr., Gobert AP, Wilson KT (2010) Polyamines impair immunity to Helicobacter pylori by inhibiting L-arginine uptake required for nitric oxide production. Gastroenterology 139:1686-1698, e1681-e1686
33. Chaturvedi R, de Sablet T, Coburn LA, Gobert AP, Wilson KT (2011) Arginine and polyamines in Helicobacter pylori-induced immune dysregulation and gastric carcinogenesis. Amino Acids (in this issue). doi:10.1007/s00726-011- 1038-4
34. Childs AC, Mehta DJ, Gerner EW (2003) Polyamine-dependent gene expression. Cell Mol Life Sci 60:1394-1406 (Pubitemid 36900522)
35. Cohen SS (1998) A guide to the polyamines. Oxford University Press, New York
36. Colotti G, Ilari A (2011) Polyamine metabolism in Leishmania: from arginine to trypanothione. Amino Acids 40:269-285
37. Compagnone A, Bandino A, Meli F, Bravoco V, Cravanzola C, Parola M, Colombatto S (2011) Polyamines modulate epithelialto- mesenchymal transition. Amino Acids (in this issue). doi: 10.1007/s00726-011-0995-y
38. Condello S, Currò M, Ferlazzo N, Caccamo D, Satriano J, Ientile R (2011a) Agmatine effects on mitochondrial membrane potential and NF-jB activation protect against rotenone-induced cell damage in human neuronal-like SH-SY5Y cells. J Neurochem 116:67-75
39. Condello S, Calabrò E, Caccamo D, Currò M, Ferlazzo N, Satriano J, Magazù S, Ientile R (2011b) Protective effects of agmatine in rotenone-induced damage of human SH-SY5Y neuroblastoma cells: Fourier transform infrared spectroscopy analysis in a model of Parkinson's disease. Amino Acids (in this issue). doi: 10.1007/s00726-011-0994-z
40. Correa-Fiz F, Reyes-Palomares A, Fajardo I, Melgarejo E, Gutierrez A, García-Ranea JA, Medina MA, Sánchez-Jiménez F (2011) Regulatory cross-talk of mouse liver polyamine and methionine metabolic pathways: a systemic approach to its physiopathological consequences. Amino Acids (in this issue). doi:10.1007/ s00726-011-1044-6
41. Deasey S, Grichenko O, Du S, Nurminskaya M (2011) Characterization of the transglutaminase gene family in zebrafish and in vivo analysis of transglutaminase-dependent bone mineralization. Amino Acids (in this issue). doi:10.1007/s00726-011-1021-0
42. Del Duca S, Cai G, Di Sandro A, Serafini-Fracassini D (2010) Compatible and self-incompatible pollination in Pyrus communis displays different polyamine levels and transglutaminase activity. Amino Acids 38:659-667
43. Di Pierro P, Mariniello L, Sorrentino A, Villalonga R, Chico B, Porta R (2010) Putrescine-polysaccharide conjugates as transglutaminase substrates and their possible use in producing crosslinked films. Amino Acids 38:669-675
44. Dias CAO, Borges Gregio AP, Rossi D, Carrilho Galvão F, Watanabe TF, Park MH, Valentini SR, Zanelli CF (2011) eIF5A interacts functionally with eEF2. Amino Acids (in this issue). doi: 10.1007/s00726-011-0985-0
45. Dulloo I, Gopalan G, Melino G, Sabapathy K (2010) The antiapoptotic DeltaNp73 is degraded in a c-Jun dependent manner upon genotoxic stress through the antizyme-mediated pathway. Proc Natl Acad Sci USA 107:4902-4907
46. Eisenberg T, Knauer H, Schauer A, Buttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Frohlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F (2009) Induction of autophagy by spermidine promotes longevity. Nat Cell Biol 11:1305-1314
47. Facchini A, Borzì RM, Olivotto E, Platano D, Pagani S, Cetrullo S, Flamigni F (2011) Role of polyamines in hypertrophy and terminal differentiation of osteoarthritic chondrocytes. Amino Acids (in this issue). doi:10.1007/s00726-011-1041-9
48. Fincato P, Moschou PN, Spedaletti V, Tavazza R, Angelini R, Federico R, Roubelakis-Angelakis KA, Tavladoraki P (2011a) Functional diversity inside the Arabidopsis polyamine oxidase gene family. J Exp Bot 62:1155-1168
49. Fincato P, Moschou PN, Ahou A, Angelini R, Roubelakis-Angelakis KA, Federico R, Tavladoraki P (2011b) The members of Arabidopsis thaliana PAO gene family exhibit distinct tissueand organ-specific expression pattern during seedling growth and flower development. Amino Acids (in this issue). doi:10.1007/ s00726-011-0999-7
50. Fingrut O, Flescher E (2002) Plant stress hormones suppress the proliferation and induce apoptosis in human cancer cells. Leukemia 16:608-616 (Pubitemid 34449741)
51. Folk JE (1983) Mechanism and basis for specificity of transglutaminase- catalyzed epsilon-(gamma-glutamyl) lysine bond formation. Adv Enzymol Relat Areas Mol Biol 54:1-56
52. Fraser AV, Goodwin AC, Hacker-Prietz A, Sugar E, Woster PM, Casero Jr. RA (2011) Knockdown of Ornithine Decarboxylase Antizyme 1 causes loss of uptake regulation leading to increased N1, N11-bis(ethyl)norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells. Amino Acids (in this issue). doi:10.1007/s00726-011-1030-z
53. Gentile A, Antognoni F, Iorio RA, Distefano G, Las Casas G, La Malfa S, Serafini-Fracassini D, Del Duca S (2011) Polyamines and transglutaminase activity are involved in compatible and self-incompatible pollination of Citrus grandis. Amino Acids (in this issue). doi:10.1007/s00726-011-1017-9
54. Giordano E, Hillary RA, Vary TC, Pegg AE, Sumner AD, Caldarera CM, Zhang X-Q, Song J, Wang JF, Cheung JY, Shantz LM (2011) Overexpression of ornithine decarboxylase decreases ventricular systolic function during induction of cardiac hypertrophy. Amino Acids (in this issue). doi:10.1007/s00726-011-1023-y
55. Goldenthal MJ, Marín-García J (2004) Mitochondrial signaling pathways: a receiver/integrator organelle. Mol Cell Biochem 262:1-16 (Pubitemid 39158049)
56. Goodwin A, Jadallah S, Toubaji A, Lecksell K, Hicks J, Kowalski J, Bova G, De Marzo A, Netto G, Casero RA Jr (2008) Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues. Prostate 68:766-772 (Pubitemid 351632948)
57. Grancara S, Battaglia V, Martinis P, Viceconte N, Agostinelli E, Toninello A, Deana R (2011) Mitochondrial oxidative stress induced by Ca2+ and monoamines. Different behaviour of liver and brain mitochondria in undergoing permeability transition. Amino Acids (in this issue). doi:10.1007/s00726-011- 0991-2
58. Griffin M, Casadio R, Bergamini CM (2002) Transglutaminases: nature's biological glues. Biochem J 368:377-396 (Pubitemid 35454517)
59. Groppa MD, Rosales EP, Iannone MF, Benavides MP (2008) Nitric oxide, polyamines and Cd-induced phytotoxicity in wheat roots. Phytochemistry 69:2609-2615
60. Handa AK, Mattoo AK (2010) Differential and functional interactions emphasize the multiple roles of polyamines in plants. Plant Physiol Biochem 48:540-546
61. Hauber J (2010) Revisiting an old acquaintance: role for eIF5A in diabetes. J Clin Invest 120:1806-1868
62. Hegardt C, Johannsson OT, Oredsson SM (2002) Rapid caspasedependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1, N11-diethylnorspermine. Eur J Biochem 269:1033-1039 (Pubitemid 34175425)
63. Hyvönen MT, Uimari A, Vepsäläinen J, Khomutov AR, Keinänen TA, Alhonen L (2011a) Tissue-specific alternative splicing of spermidine/spermine N1-acetyltransferase. Amino Acids (in this issue). doi:10.1007/s00726-011-1027-7
64. Hyvönen MT, Keinänen TA, Khomutov M, Simonian A, Vepsäläinen J, Park JH, Khomutov AR, Alhonen L, Park MH (2011b) Effects of novel C-methylated spermidine analogs on cell growth via hypusination of eukaryotic translation initiation factor 5A. Amino Acids (in this issue). doi:10.1007/s00726-011-0984-1
65. Häkkinen MR (2011) Polyamine analysis by LC-MS. Methods Mol Biol 720:505-518
66. Igarashi K, Kashiwagi K (2010) Modulation of cellular function by polyamines. Int J Biochem Cell Biol 42:39-51
67. Iismaa SE, Mearns BM, Lorand L, Graham RM (2009) Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders. Physiol Rev 89:991-1023
68. Ikeguchi Y, Bewley MC, Pegg AE (2006) Aminopropyltransferases: function, structure and genetics. J Biochem 139:1-9 (Pubitemid 43258840)
69. Ilari A, Baiocco P, Messori L, Fiorillo A, Boffi A, Gramiccia M, Di Muccio T, Colotti G (2011) A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of Trypanothione Reductase from Leishmania infantum in complex with Auranofin reveals a dual mechanism of enzyme inhibition. Amino Acids (in this issue). doi:10.1007/s00726-011-0997-9
70. Illingworth C, Michael AJ (2011) Plant ornithine decarboxylase is not post-transcriptionally feedback regulated by polyamines but can interact with a cytosolic ribosomal protein S15 polypeptide. Amino Acids (in this issue). doi:10.1007/s00726-011-1029-5
71. Iorio RA, Di Sandro A, Paris R, Pagliarani G, Tartarini S, Ricci G, Serafini Fracassini D, Verderio E, Del Duca S (2011) Simulated environmental criticalities affect transglutaminase of Malus and Corylus pollens having different allergenic potential. Amino Acids (in this issue). doi:10.1007/s00726-011-1043-7
72. Ishii I, Ikeguchi Y, Mano H, Wada M, Pegg AE, Shirahata A (2011a) Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells. Amino Acids (in this issue). doi:10.1007/s00726-011-1037-5
73. Ishii I, Suzuki T, Kaneko H, Uchida M, Suzuki Y, Higashi K, Yagi S, Ariyoshi N, Igarashi K, Kitada M (2011b) Correlation between antizyme 1 and differentiation of vascular smooth muscle cells cultured in honeycomb-like type-I collagen matrix. Amino Acids (in this issue). doi:10.1007/s00726-011- 1034-8
74. Johansson VM, Thuvesson I, Alm K, Oredsson SM (2011) Novel anti-apoptotic effect of the retinoblastoma protein - implications for polyamine analogue toxicity. Amino Acids (in this issue). doi:10.1007/s00726-011-1007-y
75. Kahana C (2007) Ubiquitin dependent and independent protein degradation in the regulation of cellular polyamines. Amino Acids 33:225-230 (Pubitemid 47222965)
76. Kahana C (2009) Antizyme and antizyme inhibitor, a regulatory tango. Cell Mol Life Sci 66:2479-2488
77. Kaiser A (2011) Translational control of eIF5a in various diseases. Amino Acids (in this issue). doi:10.1007/s00726-011-1042-8
78. Kalluri R, Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119:1420-1428
79. Kashiwagi K, Kuraishi A, Tomitori H, Igarashi A, Nishimura K, Shirahata A, Igarashi K (2000) Identification of the putrescine recognition site on polyamine transport protein PotE. J Biol Chem 275:36007-36012
80. Kashiwagi K, Shibuya S, Tomitori H, Kuraishi A, Igarashi K (1997) Excretion and uptake of putrescine by the PotE protein in Escherichia coli. J Biol Chem 272:6318-6323 (Pubitemid 27118106)
81. Kausch KD, Sobolev AP, Goyal RK, Fatima T, Laila-Beevi R, Saftner RA, Handa AK, Mattoo AK (2011) Methyl jasmonate deficiency alters cellular metabolome, including the aminome of tomato (Solanum lycopersicum L.) fruit. Amino Acids (in this issue). doi:10.1007/s00726-011-1000-5
82. Keren-Paz A, Bercovich Z, Porat Z, Erez O, Brener O, Kahana C (2006) Overexpression of antizyme-inhibitor in NIH3T3 fibroblasts provides growth advantage through neutralization of antizyme functions. Oncogene 25:5163-5172 (Pubitemid 44285985)
83. Kirschbaum J, Rebscher K, Brückner H (2000) Liquid chromatographic determination of biogenic amines in fermented foods after derivatization with 3, 5-dinitrobenzoyl chloride. J Chromatogr A 881:517-530 (Pubitemid 30332232)
84. Kleman JP, Aeschlimann D, Paulsson M, Van der Rest M (1995) Transglutaminase-catalyzed cross-linking of fibrils of collagen V/XI in A204 rhabdomyosarcoma cells. Biochemistry 34: 13768-13775
85. Koponen T, Cerrada-Gimenez M, Pirinen E, Hohtola E, Paananen J, Vuohelainen S, Tusa M, Pirnes-Karhu S, Heikkinen S, Virkama ̈ki A, Uimari A, Alhonen L, Laakso M (2011) The activation of hepatic and muscle polyamine catabolism improves glucose homeostasis. Amino Acids (in this issue). doi: 10.1007/s00726-011-1013-0
86. Kramer DL, Diegelman P, Jell J, Vujcic S, Merali S, Porter CW (2008) Polyamine acetylation modulates polyamine metabolic flux, a prelude to broader metabolic consequences. J Biol Chem 283:4241-4251
87. Kusano T, Berberich T, Tateda C, Takahashi Y (2008) Polyamines: essential factors for growth and survival. Planta 228:367-381
88. Lewis ND, Asim M, Barry DP, de Sablet T, Singh K, Piazuelo MB, Gobert AP, Chaturvedi R, Wilson KT (2011) Immune evasion by Helicobacter pylori is mediated by induction of macrophage arginase II. J Immunol 186:3632-3641
89. Li G, Regunathan S, Barrow CJ, Eshraghi J, Cooper R, Reis DJ (1994) Agmatine: an endogenous clonidine-displacing substance in the brain. Science 263:966-969 (Pubitemid 24094560)
90. Lindfors K, Kaukinen K, Mäki M (2009) A role for anti-transglutaminase 2 autoantibodies in the pathogenesis of coeliac disease? Amino Acids 36:685-691
91. Lindsay GS, Wallace HM (1999) Changes in polyamine catabolism in HL-60 human promyelogenous leukaemic cells in response to etoposide-induced apoptosis. Biochem J 337:83-87 (Pubitemid 29039086)
92. López-Contreras AJ, Ramos-Molina B, Cremades A, Peñafiel R (2010) Antizyme inhibitor 2: molecular, cellular and physiological aspects. Amino Acids 38:603-611
93. Mangold U (2006) Antizyme inhibitor: mysterious modulator of cell proliferation. Cell Mol Life Sci 63:2095-2101 (Pubitemid 44465684)
94. Martinis P, Battaglia V, Grancara S, Dalla Via L, Di Noto V, Saccoccio S, Agostinelli E, Bragadin M, Grillo MA, Toninello A (2011) Further characterization of agmatine binding to mitochondrial membranes. Involvement of imidazoline I2 receptor. Amino Acids (in this issue). doi:10.1007/s00726-011- 0992-1
95. Marton LJ, Pegg AE (1995) Polyamines as targets for therapeutic intervention. Annu Rev Pharmacol Toxicol 35:55-91
96. Marverti G, Guaitoli G, Ligabue A, Frassineti C, Monti MG, Lombardi P, Costi MP (2011) Distamycin A and derivatives as synergic drugs in cisplatin-sensitive and -resistant ovarian cancer cells. Amino Acids (in this issue). doi:10.1007/s00726-011-1039-3
97. Marverti G, Ligabue A, Guerrieri D, Paglietti G, Piras S, Costi MP, Farina D, Frassineti C, Monti MG, Moruzzi MS (2010) Spermidine/Spermine N1-acetyltranferase modulation by novel folate cycle inhibitors in cisplatin-sensitive and -resistant human ovarian cancer cell lines. Gynecol Oncol 117:202-210
98. Mattoo AK, Handa AK (2008) Higher polyamines restore and enhance metabolic memory in ripening fruit. Plant Sci 174:386-393
99. Mattoo AK, Minocha SC, Minocha R, Handa AK (2010) Polyamines and cellular metabolism in plants: transgenic approaches reveal different responses to diamine putrescine versus higher polyamines spermidine and spermine. Amino Acids 38:405-413
100. Minarini A, Milelli A, Tumiatti V, Rosini M, Bolognesi ML, Melchiorre C (2010) Synthetic polyamines: an overview of their multiple biological activities. Amino Acids 38:383-392
101. Mishina T, Fuchimukai K, Igarashi K, Tashiro K, Shiokawa K (2011) Modification of secondary head-forming activity of microinjected Db-catenin mRNA by co-injected spermine and spermidine in Xenopus early embryos. Amino Acids (in this issue). doi: 10.1007/s00726-011-0996-x
102. Morgan DML (1988) Polyamine oxidases and oxidized polyamines. In: Bachrach U, Heimer Y (eds) The physiology of polyamines (Vol. 1). CRC Press, Boca Raton, pp 203-229
103. Moschou PN, Paschalidis KA, Roubelakis-Angelakis KA (2008) Plant polyamine catabolism. The state of the art. Plant Signal Behav 3:1061-1066 (Pubitemid 352847663)
104. Nayvelt I, John S, Hsu H-C, Yang P, Liu W, Das G, Hyvonen M, Alhonen L, Keinanen T, Shirahata A, Patel R, Thomas T, Thomas TJ (2011) A potential estrogen mimetic effect of a bis(ethyl)polyamine analogue on estrogen receptor positive MCF-7 breast cancer cells. Amino Acids (in this issue). doi: 10.1007/s00726-011-1005-0
105. Nishimura K, Lee SB, Park JH, Park MH (2011) Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development. Amino Acids (in this issue). doi:10.1007/s00726-011-0986-z
106. Nurminskaya M, Magee C, Faverman L, Linsenmayer TF (2003) Chondrocyte-derived transglutaminase promotes maturation of preosteoblasts in periosteal bone. Dev Biol 263:139-152 (Pubitemid 37268009)
107. Olsen RR, Chung I, Zetter BR (2011) Knockdown of antizyme inhibitor decreases prostate tumor growth in vivo. Amino Acids (in this issue). doi:10.1007/s00726-011-1032-x
108. Ono Y, Wook Kim D, Watanabe K, Sasaki A, Niitsu M, Berberich T, Kusano T, Takahashi Y(2011) Constitutively and highly expressed Oryza sativa polyamine oxidases localize in peroxisomes and catalyze polyamine back conversion. Amino Acids (in this issue). doi:10.1007/s00726-011-1002-3
109. Park MH (2006) The post-translational synthesis of a polyaminederived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A). J Biochem 139:161-169
110. Park MH, Nishimura K, Zanelli CF, Valentini SR (2010) Functional significance of eIF5A and its hypusine modification in eukaryotes. Review. Amino Acids 38:491-500
111. Pegg AE (1988) Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy. Cancer Res 48:759-774 (Pubitemid 18061860)
112. Pegg AE (2008) Spermidine/spermine-N(1)-acetyltransferase: a key metabolic regulator. Am J Physiol Endocrinol Metab 294:E995-E1010
113. Perez-Leal O, Merali S (2011) Regulation of polyamine metabolism by translational control: a mini review. Amino Acids (in this issue). doi:10.1007/s00726-011-1036-6
114. Pietilä M, Lampinen A, Pellinen R, Alhonen L (2011) Inducible expression of antizyme 1 in prostate cancer cell lines after lentivirus mediated gene transfer. Amino Acids (in this issue). doi:10.1007/s00726-011-1033-9
115. Pignatti C, Tantini B, Stefanelli C, Flamigni F (2004) Signal transduction pathways linking polyamines to apoptosis. Amino Acids 27:359-365 (Pubitemid 40110081)
116. Pirnes-Karhu S, Sironen R, Alhonen L, Uimari A (2011) Lipopolysaccharide- induced anti-inflammatory acute phase response is enhanced in spermidine/spermine N1-acetyltransferase (SSAT) overexpressing mice. Amino Acids (in this issue). doi: 10.1007/s00726-011-1026-8
117. Poulin R, Casero RA, Soulet D (2011) Recent advances in the molecular biology of metazoan polyamine transport. Amino Acids (in this issue). doi:10.1007/s00726-011-0987-y
118. Ramos-Molina B, López-Contreras AJ, Cremades A, Peñafiel R (2011) Differential expression of ornithine decarboxylase antizyme inhibitors and antizymes in rodent tissues and human cell lines. Amino Acids (in this issue). doi:10.1007/s00726-011-1031-y
119. Reis DJ, Regunathan S (2000) Is agmatine a novel neurotransmitter in brain? Trends Pharmacol Sci 21:187-193 (Pubitemid 30243201)
120. Reyes-Palomares A, Montañez R, Sánchez-Jiménez F, Medina MÁ (2011) A combined model of hepatic polyamine and sulfur amino acid metabolism to analyze S-adenosyl methionine availability. Amino Acids (in this issue). doi:10.1007/s00726-011-1035-7
121. Rodríguez-Caso C, Montañez R, Cascante M, Sánchez-Jiménez F, Medina MA (2006) Mathematical modeling of polyamine metabolism in mammals. J Biol Chem 281:21799-21812 (Pubitemid 44181884)
122. Rosales EP, Iannone MF, Groppa MD, Benavides MP (2011a) Nitric oxide inhibits nitrate reductase activity in wheat leaves. Plant Physiol Biochem 49:124-130
123. Rosales EP, Iannone MF, Groppa MD, Benavides MP (2011b) Polyamines modulate nitrate reductase activity in wheat leaves. Involvement of nitric oxide. Amino Acids (in this issue). doi: 10.1007/s00726-011-1001-4
124. Saiki R, Park H, Ishii I, Yoshida M, Nishimura K, Toida T, Tatsukawa H, Kojima S, Ikeguchi Y, Pegg AE, Kashiwagi K, Igarashi K (2011) Brain infarction correlates more closely with acrolein than with reactive oxygen species. Biochem Biophys Res Commun 404:1044-1049
125. Satriano J, Matsufuji S, Murakami Y, Lortie MJ, Schwartz D, Kelly CJ, Hayashi S, Blantz RC (1998) Agmatine suppresses proliferation by frameshift induction of antizyme and attenuation of cellular polyamine levels. J Biol Chem 273:15313-15316 (Pubitemid 28298130)
126. Seiler N (1992) Polyamine catabolism and elimination by the vertebrate organism. In: Dowling RH, Fölsch UR, Löser G (eds) Polyamines in the gastrointestinal tract. Kluwer, Dordrecht, pp 65-85
127. Seiler N, Raul F (2005) Polyamines and apoptosis. J Cell Mol Med 9:623-642 (Pubitemid 44151950)
128. Serafini-Fracassini D, Della Mea M, Tasco G, Casadio R, Del Duca S (2009) Plant and animal transglutaminases: do similar functions imply similar structures? Amino Acids 36:643-657
129. Shanmugasundaram S, Logan-Mauney S, Burgos K, Nurminskaya M (2011) Tissue transglutaminase regulates chondrogenesis in mesenchymal stem cells on collagen type XI matrices. Amino Acids (in this issue). doi:10.1007/s00726-011-1019-7
130. Shantz LM, Giordano E (2006) Polyamine metabolism and the hypertrophic heart. In: Wang J-Y, Casero RA (eds) Polyamine cell signaling: physiology, pharmacology and cancer research. Humana Press, Totowa. ISBN 1-58829-625-3123-137
131. Shao L, Majumdar R, Minocha SC (2011) Profiling the aminopropyltransferases in plants: their structure, expression and manipulation. Amino Acids (in this issue). doi:10.1007/s00726-011-0998-8
132. Shi C, Welsh PA, Sass-Kuhn S, Wang X, McCloskey DE, Pegg AE, Feith DJ (2011) Characterization of transgenic mice with overexpression of spermidine synthase. Amino Acids (in this issue). doi:10.1007/s00726-011-1028-6
133. Soksawatmaekhin W, Uemura T, Fukiwake N, Kashiwagi K, Igarashi K (2006) Identification of the cadaverine recognition site on the cadaverine-lysine antiporter CadB. J Biol Chem281:29213-29220 (Pubitemid 44507064)
134. Sollid LM, Khosla C (2005) Future therapeutic options for celiac disease. Nat Clin Pract Gastroenterol Hepatol 2:140-147 (Pubitemid 40812513)
135. Sommer C, Hertel TC, Schmelzer CEH, Pietzsch M (2011) Investigations on the activation of recombinant microbial pro-transglutaminase: in contrast to proteinase K, dispase removes the Histidine-tag. Amino Acids (in this issue). doi:10.1007/s00726-011-1016-x
136. Stevanato R, Mondovì B, Befani O, Scarpa M, Rigo A (1994) Electrostatic control of oxidative deamination catalysed by bovine serum amine oxidase. Biochem J 299:317-320 (Pubitemid 24106325)
137. Tabolacci C, Lentini A, Provenzano B, Beninati S (2011) Evidences for a role of protein cross-links in transglutaminase-related disease. Amino Acids (in this issue). doi:10.1007/s00726-011-1011-2
138. Tabor H, Rosenthal SM, Tabor CW (1958) The biosynthesis of spermidine and spermine from putrescine and methionine. J Biol Chem 233:907-914
139. Tavladoraki P, Cona A, Federico R, Tempera G, Viceconte N, Saccoccio S, Battaglia V, Toninello A, Agostinelli E (2011) Polyamine catabolism: target for anti-proliferative therapies in animals and stress tolerance strategies in plants. Amino Acids (in this issue). doi:10.1007/s00726-011-1012-1
140. Tavladoraki P, Rossi MN, Saccuti G, Perez-Amador MA, Polticelli F, Angelini R, Federico R (2006) Heterologous expression and biochemical characterization of a polyamine oxidase from Arabidopsis involved in polyamine back-conversion. Plant Physiol 141:1519-1532 (Pubitemid 44223301)
141. Teesalu K, Panarina M, Uibo O, Uibo R, Utt M (2011) Autoantibodies from patients with celiac disease inhibit transglutaminase 2 binding to heparin/heparan sulphate and interfere with intestinal epithelial cell adhesion. Amino Acids (in this issue). doi:10.1007/s00726-011-1020-1
142. Thomas T, Thomas TJ (2001) Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell Mol Life Sci 58:244-258 (Pubitemid 32217356)
143. Tobias KE, Kahana C (1995) Exposure to ornithine results in excessive accumulation of putrescine and apoptotic cell death in ornithine decarboxylase overproducing mouse myeloma cells. Cell Growth Differ 6:1279-1285
144. Tomitori H, Kashiwagi K, Igarashi K (2011) Structure and function of polyamine-amino acid antiporters CadB and PotE in Escherichia coli. Amino Acids (in this issue). doi:10.1007/s00726-011-0989-9
145. Toninello A, Salvi M, Mondovì B (2004) Interaction of biologically active amines with mitochondria and their role in the mitochondrial- mediated pathway of apoptosis. Curr Med Chem 11:2349-2374 (Pubitemid 39172354)
146. Tseng H-C, Tang J-B, Sudhakar Gandhi PS, Luo C-W, Ou C-M, Tseng C-J, Lin H-J, Chen Y-H (2011) Mutual Adaptation between mouse transglutaminase 4 and its native substrates in the formation of copulatory plug. Amino Acids (in this issue). doi:10.1007/s00726-011-1009-9
147. Uimari A, Merentie M, Sironen R, Pirnes-Karhu S, Peräniemi S, Alhonen L (2011) Overexpression of spermidine/spermine N1- acetyltransferase or treatment with N1-N11-diethylnorspermine attenuates the severity of zinc-induced pancreatitis in mouse. Amino Acids (in this issue). doi:10.1007/s00726-011- 1025-9
148. van den Akker J, Schoorl MJ, Bakker EN, VanBavel E (2010) Small artery remodeling: current concepts and questions. J Vasc Res 47:183-202
149. van den Akker J, van Weert A, Afink G, Bakker ENTP, van der Pol E, Böing AN, Nieuwland R, VanBavel E (2011a) Transglutaminase 2 is secreted from smooth muscle cells by transamidationdependent microparticle formation. Amino Acids (in this issue). doi:10.1007/s00726-011-1010-3
150. van den Akker J, van Bavel E, van Geel R, Matlung HL, Janssen GMC, van Veelen PA, Boelens WC, De Mey JGR, Bakker EN (2011b) The redox state of transglutaminase 2 controls arterial remodeling. Plos One 6:e23067. doi:10.1371/journal.pone.0023067
151. Wang Z, Griffin M (2011) TG2 a novel extracellular protein with multiple functions. Amino Acids (in this issue). doi:10.1007/ s00726-011-1008-x
152. Wang Z, Collighan RJ, Gross SR, Danen EH, Orend G, Telci D, Griffin M (2010) RGD-independent cell adhesion via a tissue transglutaminase-fibronectin matrix promotes fibronectin fibril deposition and requires syndecan-4/2 and alpha5beta1 integrin co-signaling. J Biol Chem 285:40212-40229
153. Xu J, Wang W, Ludeman M, Cheng K, Hayami T, Lotz JC, Kapila S (2008) Chondrogenic differentiation of human mesenchymal stem cells in 3D alginate gels. Tissue Eng Part A 14:667-680 (Pubitemid 351684744)
154. Zanelli CF, Valentini SR (2007) Is there a role for eIF5A in translation? Review. Amino Acids 33:351-358 (Pubitemid 47222979)
155. Zhu Q, Huang Y, Marton LJ, Woster PM, Davidson NE, Casero RA Jr (2011) Polyamine analogues modulate gene expression by inhibiting Lysine-Specific Demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells. Amino Acids (in this issue). doi:10.1007/s00726-011-1004-1