Effects of novel C-methylated spermidine analogs on cell growth via hypusination of eukaryotic translation initiation factor 5A

Amino Acids

Volumn 42, Issue 2-3, 2012, Pages 685-695

  Hyvönen, Mervi T ^a   Keinänen, Tuomo A ^a   Khomutov, Maxim ^b   Simonian, Alina ^b   Vepsäläinen, Jouko ^a   Park, Jong Hwan ^c   Khomutov, Alex R ^b   Alhonen, Leena ^a   Park, Myung Hee ^c  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^c NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Cell growth; Deoxyhypusine synthase; EIF5A; Hypusine; Methylated spermidine; Polyamine

Indexed keywords

ALPHA METHYLATED SPERMIDINE; BETA METHYLATED SPERMIDINE; DEOXYHYPUSINE SYNTHASE; EFLORNITHINE; GAMMA METHYLATED SPERMIDINE; HYPUSINE; INITIATION FACTOR 5A; OMEGA METHYLATED SPERMIDINE; PUTRESCINE; SPERMIDINE; SPERMIDINE DERIVATIVE; SPERMINE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; INITIATION FACTOR; LYSINE; RNA BINDING PROTEIN;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DEPLETION; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; ENANTIOMER; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HYPUSINATION; IN VITRO STUDY; MALE; MOLECULAR STABILITY; POLYAMINE METABOLISM; PRIORITY JOURNAL; PROTEIN MODIFICATION; RACEMIC MIXTURE; CELL DIVISION; METABOLISM; METHYLATION; TUMOR CELL LINE; WESTERN BLOTTING;

EUKARYOTA; MAMMALIA;

BLOTTING, WESTERN; CELL DIVISION; CELL LINE, TUMOR; HUMANS; LYSINE; MALE; METHYLATION; PEPTIDE INITIATION FACTORS; RNA-BINDING PROTEINS; SPERMIDINE;

EID: 84861688175     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-011-0984-1     Document Type: Article

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