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Volumn 42, Issue 2-3, 2012, Pages 549-558

Knockdown of antizyme inhibitor decreases prostate tumor growth in vivo

Author keywords

Antizyme inhibitor; Cell proliferation; Prostate cancer; Tumor growth

Indexed keywords

ANTIZYME INHIBITOR 1; CELL PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; AZIN1 PROTEIN, HUMAN; CARRIER PROTEIN; PRIMER DNA;

EID: 84861684351     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-011-1032-x     Document Type: Article
Times cited : (14)

References (48)
  • 2
    • 0026683752 scopus 로고
    • Ornithine decarboxylase activity is critical for cell transformation
    • DOI 10.1038/360355a0
    • Auvinen M, Paasinen A, Andersson LC, Holtta E (1992) Ornithine decarboxylase activity is critical for cell transformation. Nature 360(6402):355-358. doi:10.1038/360355a0 (Pubitemid 23000675)
    • (1992) Nature , vol.360 , Issue.6402 , pp. 355-358
    • Auvinen, M.1    Paasinen, A.2    Andersson, L.C.3    Holtta, E.4
  • 3
    • 4143153834 scopus 로고    scopus 로고
    • Polyamines and cancer: Minireview article
    • Bachrach U (2004) Polyamines and cancer: minireview article. Amino Acids 26(4):307-309. doi:10.1007/s00726-004-0076-6 (Pubitemid 39093131)
    • (2004) Amino Acids , vol.26 , Issue.4 , pp. 307-309
    • Bachrach, U.1
  • 5
    • 32944470417 scopus 로고    scopus 로고
    • Emerging concepts in targeting the polyamine metabolic pathway in epithelial cancer chemoprevention and chemotherapy
    • DOI 10.1093/jb/mvj022
    • Basuroy UK, Gerner EW (2006) Emerging concepts in targeting the polyamine metabolic pathway in epithelial cancer chemoprevention and chemotherapy. J Biochem 139(1):27-33. doi: 10.1093/jb/mvj022 (Pubitemid 43258843)
    • (2006) Journal of Biochemistry , vol.139 , Issue.1 , pp. 27-33
    • Basuroy, U.K.1    Gerner, E.W.2
  • 6
    • 12844280568 scopus 로고    scopus 로고
    • Stable siRNAmediated silencing of antizyme inhibitor: Regulation of ornithine decarboxylase activity
    • doi:10.1016/j.bbrc.2004.11.172
    • Choi KS, Suh YH, Kim WH, Lee TH, Jung MH (2005) Stable siRNAmediated silencing of antizyme inhibitor: regulation of ornithine decarboxylase activity. Biochem Biophys Res Commun 328(1):206-212. doi:10.1016/j.bbrc.2004.11.172
    • (2005) Biochem Biophys Res Commun , vol.328 , Issue.1 , pp. 206-212
    • Choi, K.S.1    Suh, Y.H.2    Kim, W.H.3    Lee, T.H.4    Jung, M.H.5
  • 7
    • 0035067587 scopus 로고    scopus 로고
    • Antizyme, a mediator of ubiquitin-independent proteasomal degradation
    • DOI 10.1016/S0300-9084(01)01252-4
    • Coffino P (2001a) Antizyme, a mediator of ubiquitin-independent proteasomal degradation. Biochimie 83(3-4):319-323 (Pubitemid 32293652)
    • (2001) Biochimie , vol.83 , Issue.3-4 , pp. 319-323
    • Coffino, P.1
  • 8
    • 0035291218 scopus 로고    scopus 로고
    • Regulation of cellular polyamines by antizyme
    • DOI 10.1038/35056508
    • Coffino P (2001b) Regulation of cellular polyamines by antizyme. Nat Rev Mol Cell Biol 2(3):188-194. doi:10.1038/35056508 (Pubitemid 33675743)
    • (2001) Nature Reviews Molecular Cell Biology , vol.2 , Issue.3 , pp. 188-194
    • Coffino, P.1
  • 9
    • 4944242891 scopus 로고    scopus 로고
    • Polyamines and cancer: Old molecules, new understanding
    • DOI 10.1038/nrc1454
    • Gerner EW, Meyskens FL Jr (2004) Polyamines and cancer: old molecules, new understanding. Nat Rev Cancer 4(10):781-792. doi:10.1038/nrc1454 (Pubitemid 39331150)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.10 , pp. 781-792
    • Gerner, E.W.1    Meyskens Jr., F.L.2
  • 10
    • 0035824568 scopus 로고    scopus 로고
    • Proteasomal degradation of Smad1 induced by bone morphogenetic proteins
    • doi:10.1074/jbc.M105500200
    • Gruendler C, Lin Y, Farley J, Wang T (2001) Proteasomal degradation of Smad1 induced by bone morphogenetic proteins. J Biol Chem 276(49):46533-46543. doi:10.1074/jbc.M105500200
    • (2001) J Biol Chem , vol.276 , Issue.49 , pp. 46533-46543
    • Gruendler, C.1    Lin, Y.2    Farley, J.3    Wang, T.4
  • 11
    • 0034329458 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in normal and tumor human gastric tissue
    • doi:10.1006/geno.2000.6338
    • Jung MH, Kim SC, Jeon GA, Kim SH, Kim Y, Choi KS, Park SI, Joe MK, Kimm K (2000) Identification of differentially expressed genes in normal and tumor human gastric tissue. Genomics 69(3):281-286. doi:10.1006/geno.2000.6338
    • (2000) Genomics , vol.69 , Issue.3 , pp. 281-286
    • Jung, M.H.1    Kim, S.C.2    Jeon, G.A.3    Kim, S.H.4    Kim, Y.5    Choi, K.S.6    Park, S.I.7    Joe, M.K.8    Kimm, K.9
  • 12
    • 27744492409 scopus 로고    scopus 로고
    • Mechanisms of protein degradation: An odyssey with ODC
    • Kahana C, Asher G, Shaul Y (2005) Mechanisms of protein degradation: an odyssey with ODC. Cell Cycle 4(11):1461-1464
    • (2005) Cell Cycle , vol.4 , Issue.11 , pp. 1461-1464
    • Kahana, C.1    Asher, G.2    Shaul, Y.3
  • 13
    • 34247129066 scopus 로고    scopus 로고
    • Antizyme inhibitor: A defective ornithine decarboxylase or a physiological regulator of polyamine biosynthesis and cellular proliferation
    • DOI 10.1042/BST0350311
    • Keren-Paz A, Bercovich Z, Kahana C (2007) Antizyme inhibitor: a defective ornithine decarboxylase or a physiological regulator of polyamine biosynthesis and cellular proliferation. Biochem Soc Trans 35(Pt 2):311-313. doi:10.1042/bst0350311 (Pubitemid 46596497)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.2 , pp. 311-313
    • Keren-Paz, A.1    Bercovich, Z.2    Kahana, C.3
  • 14
    • 33747830765 scopus 로고    scopus 로고
    • Overexpression of antizyme-inhibitor in NIH3T3 fibroblasts provides growth advantage through neutralization of antizyme functions
    • DOI 10.1038/sj.onc.1209521, PII 1209521
    • Keren-Paz A, Bercovich Z, Porat Z, Erez O, Brener O, Kahana C (2006) Overexpression of antizyme-inhibitor in NIH3T3 fibroblasts provides growth advantage through neutralization of antizyme functions. Oncogene 25(37):5163-5172. doi:10.1038/ sj.onc.1209521 (Pubitemid 44285985)
    • (2006) Oncogene , vol.25 , Issue.37 , pp. 5163-5172
    • Keren-Paz, A.1    Bercovich, Z.2    Porat, Z.3    Erez, O.4    Brener, O.5    Kahana, C.6
  • 15
    • 33746102203 scopus 로고    scopus 로고
    • Regulation of cell proliferation by the antizyme inhibitor: Evidence for an antizyme-independent mechanism
    • DOI 10.1242/jcs.02966
    • Kim SW, Mangold U, Waghorne C, Mobascher A, Shantz L, Banyard J, Zetter BR (2006) Regulation of cell proliferation by the antizyme inhibitor: evidence for an antizyme-independent mechanism. J Cell Sci 119(Pt 12):2583-2591. doi:10.1242/ jcs.02966 (Pubitemid 44070439)
    • (2006) Journal of Cell Science , vol.119 , Issue.12 , pp. 2583-2591
    • Kim, S.W.1    Mangold, U.2    Waghorne, C.3    Mobascher, A.4    Shantz, L.5    Banyard, J.6    Zetter, B.R.7
  • 16
    • 0034667393 scopus 로고    scopus 로고
    • Inhibition of ornithine decarboxylase (ODC) decreases tumor vascularization and reverses spontaneous tumors in ODC/Ras transgenic mice
    • Lan L, Trempus C, Gilmour SK (2000) Inhibition of ornithine decarboxylase (ODC) decreases tumor vascularization and reverses spontaneous tumors in ODC/Ras transgenic mice. Cancer Res 60(20):5696-5703
    • (2000) Cancer Res , vol.60 , Issue.20 , pp. 5696-5703
    • Lan, L.1    Trempus, C.2    Gilmour, S.K.3
  • 18
    • 0026667106 scopus 로고
    • Regulated degradation of ornithine decarboxylase requires interaction with the polyamine-inducible protein antizyme
    • Li X, Coffino P (1992) Regulated degradation of ornithine decarboxylase requires interaction with the polyamine-inducible protein antizyme. Mol Cell Biol 12(8):3556-3562
    • (1992) Mol Cell Biol , vol.12 , Issue.8 , pp. 3556-3562
    • Li, X.1    Coffino, P.2
  • 19
    • 35348851301 scopus 로고    scopus 로고
    • Antizyme1 mediates AURKAIP1-dependent degradation of Aurora-A
    • DOI 10.1038/sj.onc.1210482, PII 1210482
    • Lim SK, Gopalan G (2007) Antizyme1 mediates AURKAIP1- dependent degradation of Aurora-A. Oncogene 26(46):6593-6603. doi:10.1038/sj.onc.1210482 (Pubitemid 47573681)
    • (2007) Oncogene , vol.26 , Issue.46 , pp. 6593-6603
    • Lim, S.K.1    Gopalan, G.2
  • 20
    • 33749050639 scopus 로고    scopus 로고
    • Antizyme inhibitor: Mysterious modulator of cell proliferation
    • DOI 10.1007/s00018-005-5583-4
    • Mangold U (2006) Antizyme inhibitor: mysterious modulator of cell proliferation. Cell Mol Life Sci 63(18):2095-2101. doi:10.1007/ s00018-005-5583-4 (Pubitemid 44465684)
    • (2006) Cellular and Molecular Life Sciences , vol.63 , Issue.18 , pp. 2095-2101
    • Mangold, U.1
  • 21
    • 38549170354 scopus 로고    scopus 로고
    • Antizyme, a mediator of ubiquitin-independent proteasomal degradation and its inhibitor localize to centrosomes and modulate centriole amplification
    • DOI 10.1038/sj.onc.1210685, PII 1210685
    • Mangold U, Hayakawa H, Coughlin M, Munger K, Zetter BR (2008) Antizyme, a mediator of ubiquitin-independent proteasomal degradation and its inhibitor localize to centrosomes and modulate centriole amplification. Oncogene 27(5):604-613. doi: 10.1038/sj.onc.1210685 (Pubitemid 351158895)
    • (2008) Oncogene , vol.27 , Issue.5 , pp. 604-613
    • Mangold, U.1    Hayakawa, H.2    Coughlin, M.3    Munger, K.4    Zetter, B.R.5
  • 23
    • 0029050287 scopus 로고
    • Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase
    • Megosh L, Gilmour SK, Rosson D, Soler AP, Blessing M, Sawicki JA, O'Brien TG (1995) Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase. Cancer Res 55(19):4205-4209
    • (1995) Cancer Res , vol.55 , Issue.19 , pp. 4205-4209
    • Megosh, L.1    Gilmour, S.K.2    Rosson, D.3    Soler, A.P.4    Blessing, M.5    Sawicki, J.A.6    O'Brien, T.G.7
  • 24
    • 0345535621 scopus 로고    scopus 로고
    • Development of difluoromethylornithine (DFMO) as a chemoprevention agent
    • Meyskens FL Jr, Gerner EW (1999) Development of difluoromethylornithine (DFMO) as a chemoprevention agent. Clin Cancer Res 5(5):945-951 (Pubitemid 29233206)
    • (1999) Clinical Cancer Research , vol.5 , Issue.5 , pp. 945-951
    • Meyskens Jr., F.L.1    Gerner, E.W.2
  • 26
    • 0031983566 scopus 로고    scopus 로고
    • Human prostatic carcinoma cell lines display altered regulation of polyamine transport in response to polyamine analogs and inhibitors
    • DOI 10.1002/(SICI)1097-0045(1 9980101)34:1<51::AID-PR OS7>3.0.CO;2-N
    • Mi Z, Kramer DL, Miller JT, Bergeron RJ, Bernacki R, Porter CW (1998) Human prostatic carcinoma cell lines display altered regulation of polyamine transport in response to polyamine analogs and inhibitors. Prostate 34(1):51-60 (Pubitemid 28023826)
    • (1998) Prostate , vol.34 , Issue.1 , pp. 51-60
    • Mi, Z.1    Kramer, D.L.2    Miller, J.T.3    Bergeron, R.J.4    Bernacki, R.5    Porter, C.W.6
  • 27
    • 0030020026 scopus 로고    scopus 로고
    • Cloning of antizyme inhibitor, a highly homologous protein to ornithine decarboxylase
    • DOI 10.1074/jbc.271.7.3340
    • Murakami Y, Ichiba T, Matsufuji S, Hayashi S (1996) Cloning of antizyme inhibitor, a highly homologous protein to ornithine decarboxylase. J Biol Chem 271(7):3340-3342 (Pubitemid 26065634)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.7 , pp. 3340-3342
    • Murakami, Y.1    Ichiba, T.2    Matsufuji, S.3    Hayashi, S.-I.4
  • 28
    • 0026714435 scopus 로고
    • Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination
    • DOI 10.1038/360597a0
    • Murakami Y, Matsufuji S, Kameji T, Hayashi S, Igarashi K, Tamura T, Tanaka K, Ichihara A (1992) Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination. Nature 360(6404):597-599. doi:10.1038/360597a0 (Pubitemid 23000711)
    • (1992) Nature , vol.360 , Issue.6404 , pp. 597-599
    • Murakami, Y.1    Matsufuji, S.2    Kameji, T.3    Hayashi, S.4    Igarashi, K.5    Tamura, T.6    Tanaka, K.7    Ichihara, A.8
  • 29
    • 67349133592 scopus 로고    scopus 로고
    • The change of antizyme inhibitor expression and its possible role during mammalian cell cycle
    • doi:10.1016/j.yexcr. 2009.04.024
    • Murakami Y, Suzuki J, Samejima K, Kikuchi K, Hascilowicz T, Murai N, Matsufuji S, Oka T (2009) The change of antizyme inhibitor expression and its possible role during mammalian cell cycle. Exp Cell Res 315(13):2301-2311. doi:10.1016/j.yexcr. 2009.04.024
    • (2009) Exp Cell Res , vol.315 , Issue.13 , pp. 2301-2311
    • Murakami, Y.1    Suzuki, J.2    Samejima, K.3    Kikuchi, K.4    Hascilowicz, T.5    Murai, N.6    Matsufuji, S.7    Oka, T.8
  • 30
    • 77953063729 scopus 로고    scopus 로고
    • Developmental alterations in expression and subcellular localization of antizyme and antizyme inhibitor and their functional importance in the murine mammary gland
    • doi: 10.1007/s00726-009-0422-9
    • Murakami Y, Suzuki J, Samejima K, Oka T (2010) Developmental alterations in expression and subcellular localization of antizyme and antizyme inhibitor and their functional importance in the murine mammary gland. Amino Acids 38(2):591-601. doi: 10.1007/s00726-009-0422-9
    • (2010) Amino Acids , vol.38 , Issue.2 , pp. 591-601
    • Murakami, Y.1    Suzuki, J.2    Samejima, K.3    Oka, T.4
  • 33
    • 77953072049 scopus 로고    scopus 로고
    • The polyamine transport system as a target for anticancer drug development
    • doi:10.1007/s00726-009-0400-2
    • Palmer AJ, Wallace HM (2010) The polyamine transport system as a target for anticancer drug development. Amino Acids 38(2):415-422. doi:10.1007/s00726- 009-0400-2
    • (2010) Amino Acids , vol.38 , Issue.2 , pp. 415-422
    • Palmer, A.J.1    Wallace, H.M.2
  • 34
    • 33744951504 scopus 로고    scopus 로고
    • Regulation of ornithine decarboxylase
    • DOI 10.1074/jbc.R500031200
    • Pegg AE (2006) Regulation of ornithine decarboxylase. J Biol Chem 281(21):14529-14532. doi:10.1074/jbc.R500031200 (Pubitemid 43855154)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.21 , pp. 14529-14532
    • Pegg, A.E.1
  • 35
    • 0032522797 scopus 로고    scopus 로고
    • Polyamines regulate expression of the neoplastic phenotype in mouse skin
    • Peralta Soler A, Gilliard G, Megosh L, George K, O'Brien TG (1998) Polyamines regulate expression of the neoplastic phenotype in mouse skin. Cancer Res 58(8):1654-1659 (Pubitemid 28215088)
    • (1998) Cancer Research , vol.58 , Issue.8 , pp. 1654-1659
    • Soler, A.P.1    Gilliard, G.2    Megosh, L.3    George, K.4    O'Brien, T.G.5
  • 36
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29(9):e45
    • (2001) Nucleic Acids Res , vol.29 , Issue.9
    • Pfaffl, M.W.1
  • 39
    • 34547669262 scopus 로고    scopus 로고
    • Regulation of ornithine decarboxylase during oncogenic transformation: Mechanisms and therapeutic potential
    • DOI 10.1007/s00726-007-0531-2, Special Issue: Polyamines and their Analogs in Cancer and other Diseases
    • Shantz LM, Levin VA (2007) Regulation of ornithine decarboxylase during oncogenic transformation: mechanisms and therapeutic potential. Amino Acids 33(2):213-223. doi:10.1007/s00726-007-0531-2 (Pubitemid 47222977)
    • (2007) Amino Acids , vol.33 , Issue.2 , pp. 213-223
    • Shantz, L.M.1    Levin, V.A.2
  • 40
    • 0031691298 scopus 로고    scopus 로고
    • Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin
    • DOI 10.1093/carcin/19.8.1409
    • Smith MK, Trempus CS, Gilmour SK (1998) Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin. Carcinogenesis 19(8):1409-1415 (Pubitemid 28409839)
    • (1998) Carcinogenesis , vol.19 , Issue.8 , pp. 1409-1415
    • Smith, M.K.1    Trempus, C.S.2    Gilmour, S.K.3
  • 41
    • 56449109565 scopus 로고    scopus 로고
    • Hypoxiamediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase
    • doi:10.1158/0008-5472.can-08-2340
    • Svensson KJ, Welch JE, Kucharzewska P, Bengtson P, Bjurberg M, Pahlman S, Ten Dam GB, Persson L, Belting M (2008) Hypoxiamediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase. Cancer Res 68(22):9291-9301. doi:10.1158/0008-5472.can-08-2340
    • (2008) Cancer Res , vol.68 , Issue.22 , pp. 9291-9301
    • Svensson, K.J.1    Welch, J.E.2    Kucharzewska, P.3    Bengtson, P.4    Bjurberg, M.5    Pahlman, S.6    Ten Dam, G.B.7    Persson, L.8    Belting, M.9
  • 42
    • 58049150521 scopus 로고    scopus 로고
    • Role of ornithine decarboxylase antizyme inhibitor in vivo
    • doi:10.1111/j.1365-2443.2008.01249.x
    • Tang H, Ariki K, Ohkido M, Murakami Y, Matsufuji S, Li Z, Yamamura K (2009) Role of ornithine decarboxylase antizyme inhibitor in vivo. Genes Cells 14(1):79-87. doi:10.1111/j.1365-2443.2008.01249.x
    • (2009) Genes Cells , vol.14 , Issue.1 , pp. 79-87
    • Tang, H.1    Ariki, K.2    Ohkido, M.3    Murakami, Y.4    Matsufuji, S.5    Li, Z.6    Yamamura, K.7
  • 43
    • 84925581435 scopus 로고    scopus 로고
    • Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma
    • 805 e791. doi:10.1053/j.gastro.2010. 06.005
    • Thompson PA, Wertheim BC, Zell JA, Chen WP, McLaren CE, LaFleur BJ, Meyskens FL, Gerner EW (2010) Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma. Gastroenterology 139(3):797-805, 805 e791. doi:10.1053/j.gastro.2010. 06.005
    • (2010) Gastroenterology , vol.139 , Issue.3 , pp. 797-805
    • Thompson, P.A.1    Wertheim, B.C.2    Zell, J.A.3    Chen, W.P.4    McLaren, C.E.5    Lafleur, B.J.6    Meyskens, F.L.7    Gerner, E.W.8
  • 44
    • 0032474907 scopus 로고    scopus 로고
    • Reduction of ornithine decarboxylase antizyme (ODC-Az) level in the 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis model
    • Tsuji T, Todd R, Meyer C, McBride J, Liao PH, Huang MF, Chou MY, DonoffRB,WongDT (1998)Reduction of ornithine decarboxylase antizyme (ODC-Az) level in the 7, 12-dimethylbenz(a)anthraceneinduced hamster buccal pouch carcinogenesis model. Oncogene 16(26):3379-3385. doi:10.1038/sj.onc.1201887 (Pubitemid 28349680)
    • (1998) Oncogene , vol.16 , Issue.26 , pp. 3379-3385
    • Tsuji, T.1    Todd, R.2    Meyer, C.3    McBride, J.4    Liao, P.-H.5    Huang, M.-F.6    Chou, M.-Y.7    Donoff, R.B.8    Wong, D.T.W.9
  • 46
  • 48
    • 68349123550 scopus 로고    scopus 로고
    • Risk of cardiovascular events in a randomized placebocontrolled, double-blind trial of difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas
    • doi:10.1158/1940-6207.capr-08-0203
    • Zell JA, Pelot D, Chen WP, McLaren CE, Gerner EW, Meyskens FL (2009) Risk of cardiovascular events in a randomized placebocontrolled, double-blind trial of difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas. Cancer Prev Res 2(3):209-212. doi:10.1158/1940-6207.capr- 08-0203
    • (2009) Cancer Prev Res , vol.2 , Issue.3 , pp. 209-212
    • Zell, J.A.1    Pelot, D.2    Chen, W.P.3    McLaren, C.E.4    Gerner, E.W.5    Meyskens, F.L.6


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