Lipopolysaccharide-induced anti-inflammatory acute phase response is enhanced in spermidine/spermine N 1-acetyltransferase (SSAT) overexpressing mice

Amino Acids

Volumn 42, Issue 2-3, 2012, Pages 473-484

  Pirnes Karhu, Sini ^a   Sironen, Reijo ^a,b   Alhonen, Leena ^a   Uimari, Anne ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Immune response; Lipopolysaccharide (LPS); Polyamine; Spermidine spermine N1 acetyltransferase (SSAT)

Indexed keywords

ACYLTRANSFERASE; ALANINE AMINOTRANSFERASE; BACTERIUM LIPOPOLYSACCHARIDE; C REACTIVE PROTEIN; CREATININE; GAMMA INTERFERON; HAPTOGLOBIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; ORNITHINE DECARBOXYLASE; OROSOMUCOID; POLYAMINE; PUTRESCINE; SPERMIDINE SPERMINE N1 ACETYLTRANSFERASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; DIAMINE ACETYLTRANSFERASE; DIAMINE N-ACETYLTRANSFERASE; LIPOPOLYSACCHARIDE; PRIMER DNA;

ACUTE PHASE RESPONSE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; GENE OVEREXPRESSION; IMMUNE RESPONSE; KIDNEY PARENCHYMA; LIVER PARENCHYMA; MORTALITY; MOUSE; NONHUMAN; POLYAMINE METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL RATE; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; CHEMICALLY INDUCED DISORDER; ENZYMOLOGY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY;

ANIMALIA; BACTERIA (MICROORGANISMS); MUS; MUS MUSCULUS;

ACETYLTRANSFERASES; ACUTE-PHASE REACTION; ANIMALS; BASE SEQUENCE; CYTOKINES; DNA PRIMERS; LIPOPOLYSACCHARIDES; MICE; SURVIVAL RATE;

EID: 84861684304     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-011-1026-8     Document Type: Article

References (47)

1. Alhonen L, Parkkinen JJ, Keinanen T, Sinervirta R, Herzig KH, Janne J (2000) Activation of polyamine catabolism in transgenic rats induces acute pancreatitis. Proc Natl Acad Sci USA97:8290-8295 (Pubitemid 30639665)
2. Babbar N, Hacker A, Huang Y, Casero RA Jr (2006) Tumor necrosis factor alpha induces spermidine/spermine N1-acetyltransferase through nuclear factor kappaB in non-small cell lung cancer cells. J Biol Chem 281:24182-24192 (Pubitemid 44274192)
3. Babbar N, Murray-Stewart T, Casero RA Jr (2007) Inflammation and polyamine catabolism: the good, the bad and the ugly. Biochem Soc Trans 35:300-304 (Pubitemid 46596495)
4. Badolato R, Wang JM, Murphy WJ, Lloyd AR, Michiel DF, Bausserman LL, Kelvin DJ, Oppenheim JJ (1994) Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes. J Exp Med 180:203-209 (Pubitemid 24181069)
5. Baek JH, Liu YV, McDonald KR, Wesley JB, Zhang H, Semenza GL (2007) Spermidine/spermine N(1)-acetyltransferase-1 binds to hypoxia-inducible factor-1alpha (HIF-1alpha) and RACK1 and promotes ubiquitination and degradation of HIF-1alpha. J Biol Chem 282:33358-33366 (Pubitemid 350159504)
6. Baydoun AR, Morgan DM (1998) Inhibition of ornithine decarboxylase potentiates nitric oxide production in LPS-activated J774 cells. Br J Pharmacol 125:1511-1516 (Pubitemid 28548564)
7. Bernacki RJ, Oberman EJ, Seweryniak KE, Atwood A, Bergeron RJ, Porter CW (1995) Preclinical antitumor efficacy of the polyamine analogue N1, N11-diethylnorspermine administered by multiple injection or continuous infusion. Clin Cancer Res 1:847-857
8. Boutten A, Dehoux M, Deschenes M, Rouzeau JD, Bories PN, Durand G (1992) Alpha 1-acid glycoprotein potentiates lipopolysaccharide- induced secretion of interleukin-1 beta, interleukin- 6 and tumor necrosis factor-alpha by human monocytes and alveolar and peritoneal macrophages. Eur J Immunol 22:2687-2695
9. Bradley JR (2008) TNF-mediated inflammatory disease. J Pathol 214:149-160 (Pubitemid 351160153)
10. Chen C, Young BA, Coleman CS, Pegg AE, Sheppard D (2004) Spermidine/spermine N1-acetyltransferase specifically binds to the integrin alpha9 subunit cytoplasmic domain and enhances cell migration. J Cell Biol 167:161-170 (Pubitemid 39363423)
11. Christenson K, Bjorkman L, Tangemo C, Bylund J (2008) Serum amyloid A inhibits apoptosis of human neutrophils via a P2X7- sensitive pathway independent of formyl peptide receptor-like 1. J Leukoc Biol 83:139-148
12. deHart GW, Jin T, McCloskey DE, Pegg AE, Sheppard D et al (2008) The alpha9beta1 integrin enhances cell migration by polyaminemediated modulation of an inward-rectifier potassium channel. Proc Natl Acad Sci USA 105:7188-7193 (Pubitemid 351754453)
13. Facchini A, Borzi RM, Marcu KB, Stefanelli C, Olivotto E, Goldring MB, Facchini A, Flamigni F (2005) Polyamine depletion inhibits NF-kappaB binding to DNA and interleukin-8 production in human chondrocytes stimulated by tumor necrosis factor-alpha. J Cell Physiol 204:956-963 (Pubitemid 41099282)
14. Fournier T, Medjoubi-N N, Porquet D (2000) Alpha-1-acid glycoprotein. Biochim Biophys Acta 1482:157-171
15. Gabay C, Kushner I (1999) Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 340:448-454 (Pubitemid 29084777)
16. Hasko G, Kuhel DG, Marton A, Nemeth ZH, Deitch EA, Szabo C (2000) Spermine differentially regulates the production of interleukin-12 p40 and interleukin-10 and suppresses the release of the T helper 1 cytokine interferon-gamma. Shock 14:144-149
17. He RL, Zhou J, Hanson CZ, Chen J, Cheng N, Ye RD (2009) Serum amyloid A induces G-CSF expression and neutrophilia via Tolllike receptor 2. Blood 113:429-437
18. Hyvonen T, Keinanen TA, Khomutov AR, Khomutov RM, Eloranta TO (1992) Monitoring of the uptake and metabolism of aminooxy analogues of polyamines in cultured cells by highperformance liquid chromatography. J Chromatogr 574:17-21
19. Hyvonen MT, Sinervirta R, Grigorenko N, Khomutov AR, Vepsalainen J, Keinanen TA, Alhonen L (2010) alpha-Methylspermidine protects against carbon tetrachloride-induced hepatic and pancreatic damage. Amino Acids 38:575-581
20. Janne J, Williams-Ashman HG (1971) On the purification of L-ornithine decarboxylase from rat prostate and effects of thiol compounds on the enzyme. J Biol Chem 246:1725-1732
21. Jirillo E, Caccavo D, Magrone T, Piccigallo E, Amati L, Lembo A, Kalis C, Gumenscheimer M (2002) The role of the liver in the response to LPS: experimental and clinical findings. J Endotoxin Res 8:319-327 (Pubitemid 35460666)
22. Kumar H, Kawai T, Akira S (2009) Toll-like receptors and innate immunity. Biochem Biophys Res Commun 388:621-625
23. Libert C, Brouckaert P, Fiers W (1994) Protection by alpha 1-acid glycoprotein against tumor necrosis factor-induced lethality. J Exp Med 180:1571-1575
24. Lin WJ, Yeh WC (2005) Implication of Toll-like receptor and tumor necrosis factor alpha signaling in septic shock. Shock 24:206-209
25. Moshage H (1997) Cytokines and the hepatic acute phase response. J Pathol 181:257-266 (Pubitemid 27156836)
26. Oh SK, Pavlotsky N, Tauber AI (1990) Specific binding of haptoglobin to human neutrophils and its functional consequences. J Leukoc Biol 47:142-148 (Pubitemid 20061667)
27. Opal SM, DePalo VA (2000) Anti-inflammatory cytokines. Chest 117:1162-1172 (Pubitemid 30228378)
28. Oyanagui Y (1984) Anti-inflammatory effects of polyamines in serotonin and carrageenan paw edemata - possible mechanism to increase vascular permeability inhibitory protein level which is regulated by glucocorticoids and superoxide radical. Agents Actions 14:228-237 (Pubitemid 14170238)
29. Pegg AE (2008) Spermidine/spermine-N(1)-acetyltransferase: a key metabolic regulator. Am J Physiol Endocrinol Metab 294:E995-E1010
30. Peranzoni E, Marigo I, Dolcetti L, Ugel S, Sonda N, Taschin E, Mantelli B, Bronte V, Zanovello P (2007) Role of arginine metabolism in immunity and immunopathology. Immunobiology 212:795-812
31. Persson L (2009) Polyamine homoeostasis. Essays Biochem 46:11-24
32. Pietila M, Alhonen L, Halmekyto M, Kanter P, Janne J, Porter CW (1997) Activation of polyamine catabolism profoundly alters tissue polyamine pools and affects hair growth and female fertility in transgenic mice overexpressing spermidine/spermine N1-acetyltransferase. J Biol Chem 272:18746-18751 (Pubitemid 27318220)
33. Pirinen E, Kuulasmaa T, Pietila M, Heikkinen S, Tusa M, Itkonen P, Boman S, Skommer J, Virkamaki A, Hohtola E, Kettunen M, Fatrai S, Kansanen E, Koota S, Niiranen K, Parkkinen J, Levonen AL, Yla-Herttuala S, Hiltunen JK, Alhonen L, Smith U, Janne J, Laakso M (2007) Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism. Mol Cell Biol 27: 4953-4967 (Pubitemid 47016144)
34. Pirinen E, Gylling H, Itkonen P, Yaluri N, Heikkinen S, Pietila M, Kuulasmaa T, Tusa M, Cerrada-Gimenez M, Pihlajamaki J, Alhonen L, Janne J, Miettinen TA, Laakso M (2010) Activated polyamine catabolism leads to low cholesterol levels by enhancing bile acid synthesis. Amino Acids 38:549-560
35. Puntambekar SS, Davis DS, Hawel L, 3rd, Crane J, Byus CV, Carson MJ (2011) LPS-induced CCL2 expression and macrophage influx into the murine central nervous system is polyaminedependent. Brain Behav Immun 25:629-639
36. Rakonczay Z Jr, Hegyi P, Dosa S, Ivanyi B, Jarmay K, Biczo G, Hracsko Z, Varga IS, Karg E, Kaszaki J, Varro A, Lonovics J, Boros I, Gukovsky I, Gukovskaya AS, Pandol SJ, Takacs T (2008) A new severe acute necrotizing pancreatitis model induced by L-ornithine in rats. Crit Care Med 36:2117-2127
37. Rasanen TL, Alhonen L, Sinervirta R, Uimari A, Kaasinen K, Keinanen T, Herzig KH, Janne J (2003) Gossypol activates pancreatic polyamine catabolism in normal rats and induces acute pancreatitis in transgenic rats over-expressing spermidine/ spermine N1-acetyltransferase. Scand J Gastroenterol 38: 787-793 (Pubitemid 36920502)
38. Sander LE, Sackett SD, Dierssen U, Beraza N, Linke RP, Muller M, Blander JM, Tacke F, Trautwein C (2010) Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function. J Exp Med 207:1453-1464
39. Seki S, Habu Y, Kawamura T, Takeda K, Dobashi H, Ohkawa T, Hiraide H (2000) The liver as a crucial organ in the first line of host defense: the roles of Kupffer cells, natural killer (NK) cells and NK1.1 Ag ? T cells in T helper 1 immune responses. Immunol Rev 174:35-46 (Pubitemid 30201377)
40. Seki E, Tsutsui H, Nakano H, Tsuji N, Hoshino K, Adachi O, Adachi K, Futatsugi S, Kuida K, Takeuchi O, Okamura H, Fujimoto J, Akira S, Nakanishi K (2001) Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta. J Immunol 166:2651-2657 (Pubitemid 32173504)
41. Shah N, Thomas T, Shirahata A, Sigal LH, Thomas TJ (1999) Activation of nuclear factor kappaB by polyamines in breast cancer cells. Biochemistry 38:14763-14774
42. Soulet D, Rivest S (2003) Polyamines play a critical role in the control of the innate immune response in the mouse central nervous system. J Cell Biol 162:257-268 (Pubitemid 36928839)
43. Van Amersfoort ES, Van Berkel TJ, Kuiper J (2003) Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clin Microbiol Rev 16:379-414 (Pubitemid 36871313)
44. Vasson MP, Roch-Arveiller M, Couderc R, Baguet JC, Raichvarg D (1994) Effects of alpha-1 acid glycoprotein on human polymorphonuclear neutrophils: influence of glycan microheterogeneity. Clin Chim Acta 224:65-71 (Pubitemid 24076065)
45. Zahedi K, Barone S, Kramer DL, Amlal H, Alhonen L, Janne J, Porter CW, Soleimani M (2010) The role of spermidine/spermine N1- acetyltransferase in endotoxin-induced acute kidney injury. Am J Physiol Cell Physiol 299:C164-C174
46. Zhang M, Caragine T, Wang H, Cohen PS, Botchkina G, Soda K, Bianchi M, Ulrich P, Cerami A, Sherry B, Tracey KJ (1997) Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counterregulatory mechanism that restrains the immune response. J Exp Med 185:1759-1768 (Pubitemid 27242197)
47. Zhu S, Ashok M, Li J, Li W, Yang H, Wang P, Tracey KJ, Sama AE, Wang H (2009) Spermine protects mice against lethal sepsis partly by attenuating surrogate inflammatory markers. Mol Med 15:275-282