Cytotoxicity of spermine oxidation products to multidrug resistant melanoma M14 ADR2 cells: Sensitization by the MDL 72527 lysosomotropic compound

International Journal of Oncology

Volumn 35, Issue 3, 2009, Pages 485-498

  Agostinelli, Enzo ^a   Condello, Maria ^b   Molinari, Agnese ^b   Tempera, Giampiero ^a   Viceconte, Nikenza ^a   Arancia, Giuseppe ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Bovine serum amine oxidase; Lysosomotropic compound; MDL 72527; Melanoma cells; Multidrug resistance; Polyamines

Indexed keywords

ACRIDINE ORANGE; ACROLEIN; ALDEHYDE; AMINE OXIDASE (FLAVIN CONTAINING); BOVINE SERUM AMINE OXIDASE; GLYCOPROTEIN P; HYDROGEN PEROXIDE; N,N' BIS(2,3 BUTADIENYL)PUTRESCINE; SPERMINE; SPERMINE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL ULTRASTRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DEAMINATION; HUMAN; HUMAN CELL; LYSOSOME MEMBRANE; MELANOMA CELL; MEMBRANE PERMEABILITY; OXIDATION; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; HUMANS; LYSOSOMES; MELANOMA; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; OXIDATION-REDUCTION; P-GLYCOPROTEIN; PUTRESCINE; SPERMINE;

EID: 70349132707     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000360     Document Type: Article

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