Knockdown of ornithine decarboxylase antizyme 1 causes loss of uptake regulation leading to increased N 1, N 11-bis(ethyl) norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells

Amino Acids

Volumn 42, Issue 2-3, 2012, Pages 529-538

  Fraser, Alison V ^a   Goodwin, Andrew C ^a   Hacker Prietz, Amy ^a   Sugar, Elizabeth ^a   Woster, Patrick M ^b   Casero Jr , Robert A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Antizyme; BENSpm; Ornithine decarboxylase; Polyamines; Spermine

Indexed keywords

ANTIZYME; ANTIZYME 1; CYCLIN D1; N1,N11 DIETHYLNORSPERMINE; ORNITHINE DECARBOXYLASE; PUTRESCINE; SMALL INTERFERING RNA; SPERMIDINE; SPERMINE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; N(1),N(11) DIETHYLNORSPERMINE; N(1),N(11)-DIETHYLNORSPERMINE; POLYAMINE; PROTEIN;

AMINE TRANSPORT; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; POLYAMINE METABOLISM; POLYAMINE TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; ENZYMOLOGY; GENETICS; LUNG TUMOR; METABOLISM; MOLECULAR GENETICS; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PATHOLOGY; TUMOR CELL LINE;

BASE SEQUENCE; BLOTTING, NORTHERN; CELL LINE, TUMOR; GENE KNOCKDOWN TECHNIQUES; HUMANS; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; POLYAMINES; PROTEINS; RNA, SMALL INTERFERING; SPERMINE;

EID: 84861698080     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-011-1030-z     Document Type: Article

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