-
1
-
-
33847026354
-
Autophagy delays apoptotic death in breast cancer cells following DNA damage
-
Abedin MJ, Wang D, McDonnell MA, Lehmann U, Kelekar A (2007) Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death Differ 14:500-510
-
(2007)
Cell Death Differ
, vol.14
, pp. 500-510
-
-
Abedin, M.J.1
Wang, D.2
McDonnell, M.A.3
Lehmann, U.4
Kelekar, A.5
-
2
-
-
77953072474
-
Polyamines: Fundamental characters in chemistry and biology
-
Agostinelli E, Marques MP, Calheiros R, Gil FP, Tempera G, Viceconte N, Battaglia V, Grancara S, Toninello A (2010a) Polyamines: fundamental characters in chemistry and biology. Amino Acids 38:393-403
-
(2010)
Amino Acids
, vol.38
, pp. 393-403
-
-
Agostinelli, E.1
Marques, M.P.2
Calheiros, R.3
Gil, F.P.4
Tempera, G.5
Viceconte, N.6
Battaglia, V.7
Grancara, S.8
Toninello, A.9
-
3
-
-
77953078312
-
Potential anticancer application of polyamine oxidation products formed by amine oxidase: A new therapeutic approach
-
Agostinelli E, Tempera G, Viceconte N, Saccoccio S, Battaglia V, Grancara S, Toninello A, Stevanato R (2010b) Potential anticancer application of polyamine oxidation products formed by amine oxidase: a new therapeutic approach. Amino Acids 38:353-368
-
(2010)
Amino Acids
, vol.38
, pp. 353-368
-
-
Agostinelli, E.1
Tempera, G.2
Viceconte, N.3
Saccoccio, S.4
Battaglia, V.5
Grancara, S.6
Toninello, A.7
Stevanato, R.8
-
4
-
-
0026647229
-
Antitumor activity of N, N'-bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts
-
Bernacki RJ, Bergeron RJ, Porter CW (1992) Antitumor activity of N, N'-bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts. Cancer Res 52:2424-2430
-
(1992)
Cancer Res
, vol.52
, pp. 2424-2430
-
-
Bernacki, R.J.1
Bergeron, R.J.2
Porter, C.W.3
-
5
-
-
0029085526
-
Preclinical antitumor efficacy of the polyamine analogue N1, N11-diethylnorspermine administered by multiple injection or continuous infusion
-
Bernacki RJ, Oberman EJ, Seweryniak KE, Atwood A, Bergeron RJ, Porter CW (1995) Preclinical antitumor efficacy of the polyamine analogue N1, N11-diethylnorspermine administered by multiple injection or continuous infusion. Clin Cancer Res 1:847-857
-
(1995)
Clin Cancer Res
, vol.1
, pp. 847-857
-
-
Bernacki, R.J.1
Oberman, E.J.2
Seweryniak, K.E.3
Atwood, A.4
Bergeron, R.J.5
Porter, C.W.6
-
6
-
-
34248228763
-
Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases
-
DOI 10.1038/nrd2243, PII NRD2243
-
Casero RA Jr, Marton LJ (2007) Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases. Nat Rev Drug Discov 6:373-390 (Pubitemid 46705201)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.5
, pp. 373-390
-
-
Casero, R.A.1
Marton, L.J.2
-
7
-
-
0035418231
-
Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells
-
Chen Y, Kramer DL, Diegelman P, Vujcic S, Porter CW (2001) Apoptotic signaling in polyamine analogue- treated SK-MEL-28 human melanoma cells. Cancer Res 61:6437-6444 (Pubitemid 32783249)
-
(2001)
Cancer Research
, vol.61
, Issue.17
, pp. 6437-6444
-
-
Chen, Y.1
Kramer, D.L.2
Diegelman, P.3
Vujcic, S.4
Porter, C.W.5
-
8
-
-
0030659113
-
11 diethylnorspermine in patients with advanced malignancy
-
DOI 10.1023/A:1005827231849
-
Creaven PJ, Perez R, Pendyala L, Meropol NJ, Loewen G, Levine E, Berghorn E, Raghavan D (1997) Unusual central nervous system toxicity in a phase I study of N1, N11-diethylnorspermine in patients with advanced malignancy. Invest New Drugs 15:227-234 (Pubitemid 27453877)
-
(1997)
Investigational New Drugs
, vol.15
, Issue.3
, pp. 227-234
-
-
Creaven, P.J.1
Perez, R.2
Pendyala, L.3
Meropol, N.J.4
Loewen, G.5
Levine, E.6
Berghorn, E.7
Raghavan, D.8
-
9
-
-
0033214906
-
The polyamine oxidase inhibitor MDL-72,527 selectively induces apoptosis of transformed hematopoietic cells through lysosomotropic effects
-
Dai H, Kramer DL, Yang C, Murti KG, Porter CW, Cleveland JL (1999) The polyamine oxidase inhibitor MDL-72, 527 selectively induces apoptosis of transformed hematopoietic cells through lysosomotropic effects. Cancer Res 59:4944-4954 (Pubitemid 29472900)
-
(1999)
Cancer Research
, vol.59
, Issue.19
, pp. 4944-4954
-
-
Dai, H.1
Kramer, D.L.2
Yang, C.3
Murti, K.G.4
Porter, C.W.5
Cleveland, J.L.6
-
10
-
-
33744484533
-
Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cells
-
Daniel F, Legrand A, Pessayre D, Vadrot N, Descatoire V, Bernuau D (2006) Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cells. World J Gastroenterol 12:2895-2900 (Pubitemid 43805460)
-
(2006)
World Journal of Gastroenterology
, vol.12
, Issue.19
, pp. 2895-2900
-
-
Daniel, F.1
Legrand, A.2
Pessayre, D.3
Vadrot, N.4
Descatoire, V.5
Bernuau, D.6
-
11
-
-
33947427915
-
Resveratrol impairs the formation of MDA-MB-231 multicellular tumor spheroids concomitant with ceramide accumulation
-
DOI 10.1016/j.canlet.2006.08.013, PII S0304383506005027
-
Dolfini E, Roncoroni L, Dogliotti E, Sala G, Erba E, Sacchi N, Ghidoni R (2007) Resveratrol impairs the formation of MDAMB- 231 multicellular tumor spheroids concomitant with ceramide accumulation. Cancer Lett 249:143-147 (Pubitemid 46452922)
-
(2007)
Cancer Letters
, vol.249
, Issue.2
, pp. 143-147
-
-
Dolfini, E.1
Roncoroni, L.2
Dogliotti, E.3
Sala, G.4
Erba, E.5
Sacchi, N.6
Ghidoni, R.7
-
12
-
-
70449529855
-
Induction of autophagy by spermidine promotes longevity
-
Eisenberg T, Knauer H, Schauer A, Buttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L et al (2009) Induction of autophagy by spermidine promotes longevity. Nat Cell Biol 11:1305-1314
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1305-1314
-
-
Eisenberg, T.1
Knauer, H.2
Schauer, A.3
Buttner, S.4
Ruckenstuhl, C.5
Carmona-Gutierrez, D.6
Ring, J.7
Schroeder, S.8
Magnes, C.9
Antonacci, L.10
Fussi, H.11
Deszcz, L.12
-
13
-
-
0033835275
-
Molecular correlates of the action of bis(ethyl)polyamines in breast cancer cell growth inhibition and apoptosis
-
Faaland CA, Thomas TJ, Balabhadrapathruni S, Langer T, Mian S, Shirahata A, Gallo MA, Thomas T (2000) Molecular correlates of the action of bis(ethyl)polyamines in breast cancer cell growth inhibition and apoptosis. Biochem Cell Biol 78:415-426
-
(2000)
Biochem Cell Biol
, vol.78
, pp. 415-426
-
-
Faaland, C.A.1
Thomas, T.J.2
Balabhadrapathruni, S.3
Langer, T.4
Mian, S.5
Shirahata, A.6
Gallo, M.A.7
Thomas, T.8
-
14
-
-
4944242891
-
Polyamines and cancer: Old molecules, new understanding
-
DOI 10.1038/nrc1454
-
Gerner EW, Meyskens FL Jr (2004) Polyamines and cancer: old molecules, new understanding. Nat Rev Cancer 4:781-792 (Pubitemid 39331150)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.10
, pp. 781-792
-
-
Gerner, E.W.1
Meyskens Jr., F.L.2
-
15
-
-
77953060178
-
Metabolism of N-alkylated spermine analogues by polyamine and spermine oxidases
-
Häkkinen MR, Hyvönen MT, Auriola S, Casero RA Jr, Vepsäläinen J, Khomutov AR, Alhonen L, Keinänen TA (2009) Metabolism of N-alkylated spermine analogues by polyamine and spermine oxidases. Amino Acids 38:369-381
-
(2009)
Amino Acids
, vol.38
, pp. 369-381
-
-
Häkkinen, M.R.1
Hyvönen, M.T.2
Auriola, S.3
Casero Jr., R.A.4
Vepsäläinen, J.5
Khomutov, A.R.6
Alhonen, L.7
Keinänen, T.A.8
-
16
-
-
0026504737
-
Monitoring of the uptake and metabolism of aminooxy analogues of polyamines in cultured cells by highperformance liquid chromatography
-
Hyvönen T, Keinänen TA, Khomutov AR, Khomutov RM, Eloranta TO (1992) Monitoring of the uptake and metabolism of aminooxy analogues of polyamines in cultured cells by highperformance liquid chromatography. J Chromatogr 574:17-21
-
(1992)
J Chromatogr
, vol.574
, pp. 17-21
-
-
Hyvönen, T.1
Keinänen, T.A.2
Khomutov, A.R.3
Khomutov, R.M.4
Eloranta, T.O.5
-
17
-
-
0015239342
-
On the purification of Lornithine decarboxylase from rat prostate and effects of thiol compounds on the enzyme
-
Jänne J, Williams-Ashman HG (1971) On the purification of Lornithine decarboxylase from rat prostate and effects of thiol compounds on the enzyme. J Biol Chem 246:1725-1732
-
(1971)
J Biol Chem
, vol.246
, pp. 1725-1732
-
-
Jänne, J.1
Williams-Ashman, H.G.2
-
18
-
-
54249107573
-
Regulation of estrogenic effects by beclin 1 in breast cancer cells
-
John S, Nayvelt I, Hsu HC, Yang P, Liu W, Das GM, Thomas T, Thomas TJ (2008) Regulation of estrogenic effects by beclin 1 in breast cancer cells. Cancer Res 68:7855-7863
-
(2008)
Cancer Res
, vol.68
, pp. 7855-7863
-
-
John, S.1
Nayvelt, I.2
Hsu, H.C.3
Yang, P.4
Liu, W.5
Das, G.M.6
Thomas, T.7
Thomas, T.J.8
-
19
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y, Yoshimori T (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19:5720-5728
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
20
-
-
59249102240
-
Cytosolic LC3 ratio as a quantitative index of macroautophagy
-
Kadowaki M, Karim MR (2009) Cytosolic LC3 ratio as a quantitative index of macroautophagy. Methods Enzymol 452:199-213
-
(2009)
Methods Enzymol
, vol.452
, pp. 199-213
-
-
Kadowaki, M.1
Karim, M.R.2
-
21
-
-
64049119546
-
Unique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity
-
Karmakar S, Foster EA, Smith CL (2009) Unique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity. Endocrinology 150:1588-1596
-
(2009)
Endocrinology
, vol.150
, pp. 1588-1596
-
-
Karmakar, S.1
Foster, E.A.2
Smith, C.L.3
-
22
-
-
2142652244
-
Therapeutic targeting in the estrogen receptor hormonal pathway
-
Katzenellenbogen BS, Frasor J (2004) Therapeutic targeting in the estrogen receptor hormonal pathway. Semin Oncol 31:28-38 (Pubitemid 38543938)
-
(2004)
Seminars in Oncology
, vol.31
, Issue.1 SUPPL. 3
, pp. 28-38
-
-
Katzenellenbogen, B.S.1
Frasor, J.2
-
23
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC et al (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4:151-175 (Pubitemid 351231180)
-
(2008)
Autophagy
, vol.4
, Issue.2
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
Aliev, G.5
Askew, D.S.6
Baba, M.7
Baehrecke, E.H.8
Bahr, B.A.9
Ballabio, A.10
Bamber, B.A.11
Bassham, D.C.12
Bergamini, E.13
Bi, X.14
Biard-Piechaczyk, M.15
Blum, J.S.16
Bredesen, D.E.17
Brodsky, J.L.18
Brumell, J.H.19
Brunk, U.T.20
Bursch, W.21
Camougrand, N.22
Cebollero, E.23
Cecconi, F.24
Chen, Y.25
Chin, L.-S.26
Choi, A.27
Chu, C.T.28
Chung, J.29
Clarke, P.G.H.30
Clark, R.S.B.31
Clarke, S.G.32
Clave, C.33
Cleveland, J.L.34
Codogno, P.35
Colombo, M.I.36
Cotomontes, A.37
Cregg, J.M.38
Cuervo, A.M.39
Debnath, J.40
Demarchi, F.41
Dennis, P.B.42
Dennis, P.A.43
Deretic, V.44
Devenish, R.J.45
Di Sano, F.46
Dice, J.F.47
DiFiglia, M.48
Dinesh-Kumar, S.49
Distelhorst, C.W.50
Djavaheri-Mergny, M.51
Dorsey, F.C.52
Droge, W.53
Dron, M.54
Dunn Jr., W.A.55
Duszenko, M.56
Eissa, N.T.57
Elazar, Z.58
Esclatine, A.59
Eskelinen, E.-L.60
Fesus, L.61
Finley, K.D.62
Fuentes, J.M.63
Fueyo, J.64
Fujisaki, K.65
Galliot, B.66
more..
-
24
-
-
77956992175
-
Mechanism of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation
-
Konduri SD, Medisetty R, Liu W, Kaipparettu BA, Srivastava P, Brauch H, Fritz P, Swetzig WM, Gardner AE, Khan SA, Das GM (2010) Mechanism of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation. Proc Natl Acad Sci USA 107:15081-15086
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15081-15086
-
-
Konduri, S.D.1
Medisetty, R.2
Liu, W.3
Kaipparettu, B.A.4
Srivastava, P.5
Brauch, H.6
Fritz, P.7
Swetzig, W.M.8
Gardner, A.E.9
Khan, S.A.10
Das, G.M.11
-
25
-
-
0032170524
-
Lysosomal sequestration of polyamine analogues in Chinese hamster ovary cells resistant to the S-adenosylmethionine decarboxylase inhibitor, CGP- 48664
-
Kramer DL, Black JD, Mett H, Bergeron RJ, Porter CW (1998) Lysosomal sequestration of polyamine analogues in Chinese hamster ovary cells resistant to the S-adenosylmethionine decarboxylase inhibitor, CGP-48664. Cancer Res 58:3883-3890 (Pubitemid 28405644)
-
(1998)
Cancer Research
, vol.58
, Issue.17
, pp. 3883-3890
-
-
Kramer, D.L.1
Black, J.D.2
Mett, H.3
Bergeron, R.J.4
Porter, C.W.5
-
26
-
-
0034030477
-
Polyamine profiles in tumor, normal tissue of the homologous breast, blood, and urine of breast cancer sufferers
-
DOI 10.1023/A:1006319818530
-
Leveque J, Foucher F, Bansard JY, Havouis R, Grall JY, Moulinoux JP (2000a) Polyamine profiles in tumor, normal tissue of the homologous breast, blood, and urine of breast cancer sufferers. Breast Cancer Res Treat 60:99-105 (Pubitemid 30307469)
-
(2000)
Breast Cancer Research and Treatment
, vol.60
, Issue.2
, pp. 99-105
-
-
Leveque, J.1
Foucher, F.2
Bansard, J.-Y.3
Havouis, R.4
Grall, J.-Y.5
Moulinoux, J.-P.6
-
27
-
-
0034113012
-
Benefits of complete polyamine deprivation in hormone responsive and hormone resistant MCF-7 human breast adenocarcihoma in vivo
-
Leveque J, Foucher F, Havouis R, Desury D, Grall JY, Moulinoux JP (2000b) Benefits of complete polyamine deprivation in hormone responsive and hormone resistant MCF-7 human breast adenocarcinoma in vivo. Anticancer Res 20:97-101 (Pubitemid 30189739)
-
(2000)
Anticancer Research
, vol.20
, Issue.1 A
, pp. 97-101
-
-
Leveque, J.1
Foucher, F.2
Havouis, R.3
Desury, D.4
Grall, J.-Y.5
Moulinoux, J.-P.6
-
28
-
-
41149098579
-
Estrogen receptors outside the nucleus in breast cancer
-
DOI 10.1007/s10549-007-9618-4
-
Levin ER, Pietras RJ (2008) Estrogen receptors outside the nucleus in breast cancer. Breast Cancer Res Treat 108:351-361 (Pubitemid 351431076)
-
(2008)
Breast Cancer Research and Treatment
, vol.108
, Issue.3
, pp. 351-361
-
-
Levin, E.R.1
Pietras, R.J.2
-
29
-
-
25144506835
-
Autophagy in cell death: An innocent convict?
-
DOI 10.1172/JCI26390
-
Levine B, Yuan J (2005) Autophagy in cell death: an innocent convict? J Clin Invest 115:2679-2688 (Pubitemid 41434392)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.10
, pp. 2679-2688
-
-
Levine, B.1
Yuan, J.2
-
30
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B (1999) Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402:672-676 (Pubitemid 129516338)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
31
-
-
3042547161
-
The G protein-coupled receptor GPR30 Mediates c-fos up-regulation by 17β-estradiol and phytoestrogens in breast cancer cells
-
DOI 10.1074/jbc.M403588200
-
Maggiolini M, Vivacqua A, Fasanella G, Recchia AG, Sisci D, Pezzi V, Montanaro D, Musti AM, Picard D, Ando S (2004) The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells. J Biol Chem 279:27008-27016 (Pubitemid 38812536)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.26
, pp. 27008-27016
-
-
Maggiolini, M.1
Vivacqua, A.2
Fasanella, G.3
Recchia, A.G.4
Sisci, D.5
Pezzi, V.6
Montanaro, D.7
Musti, A.M.8
Picard, D.9
Ando, S.10
-
32
-
-
0026779817
-
Role of polyamines in the growth of hormone- responsive and - Resistant human breast cancer cells in nude mice
-
Manni A, Badger B, Martel J, Demers L (1992) Role of polyamines in the growth of hormone- responsive and - resistant human breast cancer cells in nude mice. Cancer Lett 66:1-9
-
(1992)
Cancer Lett
, vol.66
, pp. 1-9
-
-
Manni, A.1
Badger, B.2
Martel, J.3
Demers, L.4
-
33
-
-
0029081697
-
Induction of programmed cell death in human breast cancer cells by an unsymmetrically alkylated polyamine analogue
-
McCloskey DE, Casero RA Jr, Woster PM, Davidson NE (1995) Induction of programmed cell death in human breast cancer cells by an unsymmetrically alkylated polyamine analogue. Cancer Res 55:3233-3236
-
(1995)
Cancer Res
, vol.55
, pp. 3233-3236
-
-
McCloskey, D.E.1
Casero Jr., R.A.2
Woster, P.M.3
Davidson, N.E.4
-
34
-
-
28844445488
-
11- diethylnorspermine on melanoma cell proliferation
-
DOI 10.1002/ijc.21359
-
Minchin RF, Knight S, Arulpragasam A, Fogel-Petrovic M (2006) Concentration-dependent effects of N1, N11-diethylnorspermine on melanoma cell proliferation. Int J Cancer 118:509-512 (Pubitemid 41779094)
-
(2006)
International Journal of Cancer
, vol.118
, Issue.2
, pp. 509-512
-
-
Minchin, R.F.1
Knight, S.2
Arulpragasam, A.3
Fogel-Petrovic, M.4
-
35
-
-
0031016204
-
Effects of chain length modification and bis(ethyl) substitution of spermine analogs on purine-purine-pyrimidine triplex DNA stabilization, aggregation, and conformational transitions
-
DOI 10.1021/bi9624494
-
Musso M, Thomas T, Shirahata A, Sigal LH, Van Dyke MW, Thomas TJ (1997) Effects of chain length modification and bis(ethyl) substitution of spermine analogs on purine-purine-pyrimidine triplex DNA stabilization, aggregation, and conformational transitions. Biochemistry 36:1441-1449 (Pubitemid 27074968)
-
(1997)
Biochemistry
, vol.36
, Issue.6
, pp. 1441-1449
-
-
Musso, M.1
Thomas, T.2
Shirahata, A.3
Sigal, L.H.4
Van Dyke, M.W.5
Thomas, T.J.6
-
36
-
-
57249083972
-
Structural basis of target recognition by Atg8/LC3 during selective autophagy
-
Noda NN, Kumeta H, Nakatogawa H, Satoo K, Adachi W, Ishii J, Fujioka Y, Ohsumi Y, Inagaki F (2008) Structural basis of target recognition by Atg8/LC3 during selective autophagy. Genes Cells 13:1211-1218
-
(2008)
Genes Cells
, vol.13
, pp. 1211-1218
-
-
Noda, N.N.1
Kumeta, H.2
Nakatogawa, H.3
Satoo, K.4
Adachi, W.5
Ishii, J.6
Fujioka, Y.7
Ohsumi, Y.8
Inagaki, F.9
-
37
-
-
70350537033
-
Nuclear receptor coregulators in cancer biology
-
O'Malley BW, Kumar R (2009) Nuclear receptor coregulators in cancer biology. Cancer Res 69:8217-8222
-
(2009)
Cancer Res
, vol.69
, pp. 8217-8222
-
-
O'Malley, B.W.1
Kumar, R.2
-
38
-
-
77953072049
-
The polyamine transport system as a target for anticancer drug development
-
Palmer AJ, Wallace HM (2010) The polyamine transport system as a target for anticancer drug development. Amino Acids 38:415-422
-
(2010)
Amino Acids
, vol.38
, pp. 415-422
-
-
Palmer, A.J.1
Wallace, H.M.2
-
39
-
-
28844480406
-
2 in polyamine analogue-treated human breast cancer cell lines
-
DOI 10.1074/jbc.M508177200
-
Pledgie A, Huang Y, Hacker A, Zhang Z, Woster PM, Davidson NE, Casero RA Jr (2005) Spermine oxidase SMO(PAOh1), Not N1- acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines. J Biol Chem 280:39843-39851 (Pubitemid 41779118)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.48
, pp. 39843-39851
-
-
Pledgie, A.1
Huang, Y.2
Hacker, A.3
Zhang, Z.4
Woster, P.M.5
Davidson, N.E.6
Casero Jr., R.A.7
-
40
-
-
0025267832
-
Morphological evidence for an apparent lysosomotropic activity by unsaturated putrescine analogues
-
Porter CW, Stanek J, Black J, Vaughan M, Ganis B, Pleshkewych A (1990) Morphological evidence for an apparent lysosomotropic activity by unsaturated putrescine analogues. Cancer Res 50:1929-1935 (Pubitemid 20098846)
-
(1990)
Cancer Research
, vol.50
, Issue.6
, pp. 1929-1935
-
-
Porter, C.W.1
Stanek, J.2
Black, J.3
Vaughan, M.4
Ganis, B.5
Pleshkewych, A.6
-
41
-
-
0027338998
-
11-bis(ethyl)norspermine against human melanoma xenografts and possible biochemical correlates of drug action
-
Porter CW, Bernacki RJ, Miller J, Bergeron RJ (1993) Antitumor activity of N1, N11-bis(ethyl)norspermine against human melanoma xenografts and possible biochemical correlates of drug action. Cancer Res 53:581-586 (Pubitemid 23059440)
-
(1993)
Cancer Research
, vol.53
, Issue.3
, pp. 581-586
-
-
Porter, C.W.1
Bernacki, R.J.2
Miller, J.3
Bergeron, R.J.4
-
42
-
-
42549085713
-
Difference between genomic actions of estrogen versus raloxifene in human ovarian cancer cell lines
-
DOI 10.1038/sj.onc.1210926, PII 1210926
-
Sasaki H, Hayakawa J, Terai Y, Kanemura M, Tanabe-Kimura A, Kamegai H, Seino-Noda H, Ezoe S, Matsumura I, Kanakura Y, Sakata M, Tasaka K et al (2008) Difference between genomic actions of estrogen versus raloxifene in human ovarian cancer cell lines. Oncogene 27:2737-2745 (Pubitemid 351581462)
-
(2008)
Oncogene
, vol.27
, Issue.19
, pp. 2737-2745
-
-
Sasaki, H.1
Hayakawa, J.2
Terai, Y.3
Kanemura, M.4
Tanabe-Kimura, A.5
Kamegai, H.6
Seino-Noda, H.7
Ezoe, S.8
Matsumura, I.9
Kanakura, Y.10
Sakata, M.11
Tasaka, K.12
Ohmichi, M.13
-
43
-
-
0642364447
-
Resveratrol induces growth inhibition and apoptosis in metastatic breast cancer cells via de novo ceramide signaling
-
DOI 10.1096/fj.03-0292fje
-
Scarlatti F, Sala G, Somenzi G, Signorelli P, Sacchi N, Ghidoni R (2003) Resveratrol induces growth inhibition and apoptosis in metastatic breast cancer cells vid de novo ceramide signaling. FASEB J 17:2339-2341 (Pubitemid 39561486)
-
(2003)
FASEB Journal
, vol.17
, Issue.15
, pp. 2339-2341
-
-
Scarlatti, F.1
Sala, G.2
Somenzi, G.3
Signorelli, P.4
Sacchi, N.5
Ghidoni, R.6
-
44
-
-
47249094223
-
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
-
DOI 10.1038/cdd.2008.51, PII CDD200851
-
Scarlatti F, Maffei R, Beau I, Codogno P, Ghidoni R (2008) Role of non-canonical Beclin 1- independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Differ 15:1318-1329 (Pubitemid 351984760)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.8
, pp. 1318-1329
-
-
Scarlatti, F.1
Maffei, R.2
Beau, I.3
Codogno, P.4
Ghidoni, R.5
-
45
-
-
0035967111
-
Regulation of estrogenic and nuclear factor κB functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells
-
DOI 10.1038/sj.onc.1204247
-
Shah N, Thomas TJ, Lewis JS, Klinge CM, Shirahata A, Gelinas C, Thomas T (2001) Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells. Oncogene 20:1715-1729 (Pubitemid 32368018)
-
(2001)
Oncogene
, vol.20
, Issue.14
, pp. 1715-1729
-
-
Shah, N.1
Thomas, T.J.2
Lewis, J.S.3
Klinge, C.M.4
Shirahata, A.5
Gelinas, C.6
Thomas, T.7
-
46
-
-
0032875359
-
Antitumor effects of bis(ethyl)polyamine analogs on mammary tumor development in FVB/NTgN (MMTVneu) transgenic mice
-
DOI 10.1016/S0304-3835(99)00215-3, PII S0304383599002153
-
Shah N, Antony T, Haddad S, Amenta P, Shirahata A, Thomas TJ, Thomas T (1999) Antitumor effects of bis(ethyl)polyamine analogs on mammary tumor development in FVB/NTgN (MMTVneu) transgenic mice. Cancer Lett 146:15-23 (Pubitemid 29462552)
-
(1999)
Cancer Letters
, vol.146
, Issue.1
, pp. 15-23
-
-
Shah, N.1
Antony, T.2
Haddad, S.3
Amenta, P.4
Shirahata, A.5
Thomas, T.J.6
Thomas, T.7
-
47
-
-
0026665552
-
Differential effects of the spermine analog, N1, N12- bis(ethyl)-spermine, on polyamine metabolism and cell growth in human melanoma cell lines and melanocytes
-
Shappell NW, Miller JT, Bergeron RJ, Porter CW (1992) Differential effects of the spermine analog, N1, N12- bis(ethyl)-spermine, on polyamine metabolism and cell growth in human melanoma cell lines and melanocytes. Anticancer Res 12:1083-1089
-
(1992)
Anticancer Res
, vol.12
, pp. 1083-1089
-
-
Shappell, N.W.1
Miller, J.T.2
Bergeron, R.J.3
Porter, C.W.4
-
48
-
-
60849133029
-
The polyamine analogue N1, N11- diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines
-
Stanic I, Facchini A, Borzi RM, Stefanelli C, Flamigni F (2009) The polyamine analogue N1, N11- diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines. J Cell Physiol 219:109-116
-
(2009)
J Cell Physiol
, vol.219
, pp. 109-116
-
-
Stanic, I.1
Facchini, A.2
Borzi, R.M.3
Stefanelli, C.4
Flamigni, F.5
-
49
-
-
0035094510
-
11-diethylnorspermine (DENSPM) administered TID for 6 days in patients with advanced malignancies
-
DOI 10.1023/A:1006448516938
-
Streiff RR, Bender JF (2001) Phase 1 study of N1-N11-diethylnorspermine (DENSPM) administered TID for 6 days in patients with advanced malignancies. Invest New Drugs 19:29-39 (Pubitemid 32209783)
-
(2001)
Investigational New Drugs
, vol.19
, Issue.1
, pp. 29-39
-
-
Streiff, R.R.1
Bender, J.F.2
-
51
-
-
4644325161
-
Estrogen receptors as targets for drug development for breast cancer, osteoporosis and cardiovascular diseases
-
DOI 10.2174/1568009043332880
-
Thomas T, Gallo MA, Thomas TJ (2004) Estrogen receptors as targets for drug development for breast cancer, osteoporosis and cardiovascular diseases. Curr Cancer Drug Targets 4:483-499 (Pubitemid 39304492)
-
(2004)
Current Cancer Drug Targets
, vol.4
, Issue.6
, pp. 483-499
-
-
Thomas, T.1
Gallo, M.A.2
Thomas, T.J.3
-
52
-
-
0028265460
-
Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: Therapeutic implications
-
Thomas T, Thomas TJ (1994a) Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications. Breast Cancer Res Treat 29:189-201 (Pubitemid 24112620)
-
(1994)
Breast Cancer Research and Treatment
, vol.29
, Issue.2
, pp. 189-201
-
-
Thomas, T.1
Thomas, T.J.2
-
53
-
-
0028205818
-
Regulation of cyclin B1 by estradiol and polyamines in MCF-7 breast cancer cells
-
Thomas T, Thomas TJ (1994b) Regulation of cyclin B1 by estradiol and polyamines in MCF-7 breast cancer cells. Cancer Res 54:1077-1084 (Pubitemid 24085466)
-
(1994)
Cancer Research
, vol.54
, Issue.4
, pp. 1077-1084
-
-
Thomas, T.1
Thomas, T.J.2
-
54
-
-
0035099627
-
Polyamines in cell growth and cell death: Molecular mechanisms and therapeutic applications
-
Thomas T, Thomas TJ (2001) Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell Mol Life Sci 58:244-258 (Pubitemid 32217356)
-
(2001)
Cellular and Molecular Life Sciences
, vol.58
, Issue.2
, pp. 244-258
-
-
Thomas, T.1
Thomas, T.J.2
-
56
-
-
68749096058
-
Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts
-
Uimari A, Keinänen TA, Karppinen A, Woster P, Uimari P, Jänne J, Alhonen L (2009) Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts. Biochem J 422:101-109
-
(2009)
Biochem J
, vol.422
, pp. 101-109
-
-
Uimari, A.1
Keinänen, T.A.2
Karppinen, A.3
Woster, P.4
Uimari, P.5
Jänne, J.6
Alhonen, L.7
-
57
-
-
33646239176
-
Physiologic levels of 2-methoxyestradiol interfere with nongenomic signaling of 17beta-estradiol in human breast cancer cells
-
Vijayanathan V, Venkiteswaran S, Nair SK, Verma A, Thomas TJ, Zhu BT, Thomas T (2006) Physiologic levels of 2-methoxyestradiol interfere with nongenomic signaling of 17beta-estradiol in human breast cancer cells. Clin Cancer Res 12:2038-2048
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2038-2048
-
-
Vijayanathan, V.1
Venkiteswaran, S.2
Nair, S.K.3
Verma, A.4
Thomas, T.J.5
Zhu, B.T.6
Thomas, T.7
-
58
-
-
59149104324
-
A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family
-
Vogel CF, Matsumura F (2009) A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family. Biochem Pharmacol 77:734-745
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 734-745
-
-
Vogel, C.F.1
Matsumura, F.2
-
59
-
-
0346734280
-
11-Diethylnorspermine (DENSpm) Daily for Five Days Every 21 Days in Patients with Previously Treated Metastatic Breast Cancer
-
Wolff AC, Armstrong DK, Fetting JH, Carducci MK, Riley CD, Bender JF, Casero RA Jr, Davidson NE (2003) A Phase II study of the polyamine analog N1, N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer. Clin Cancer Res 9:5922-5928 (Pubitemid 38018077)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.16
, pp. 5922-5928
-
-
Wolff, A.C.1
Armstrong, D.K.2
Fetting, J.H.3
Carducci, M.K.4
Riley, C.D.5
Bender, J.F.6
Casero Jr., R.A.7
Davidson, N.E.8
-
60
-
-
30944469849
-
Estrogen carcinogenesis in breast cancer
-
Yager JD, Davidson NE (2006) Estrogen carcinogenesis in breast cancer. N Engl J Med 354:270-282
-
(2006)
N Engl J Med
, vol.354
, pp. 270-282
-
-
Yager, J.D.1
Davidson, N.E.2
-
61
-
-
64049113909
-
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol- 3-kinase complex
-
Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, Heintz N, Yue Z (2009) Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol- 3-kinase complex. Nat Cell Biol 11:468-476
-
(2009)
Nat Cell Biol
, vol.11
, pp. 468-476
-
-
Zhong, Y.1
Wang, Q.J.2
Li, X.3
Yan, Y.4
Backer, J.M.5
Chait, B.T.6
Heintz, N.7
Yue, Z.8
-
62
-
-
0031573408
-
A one-step fluorometric method for the continuous measurement of monoamine oxidase activity
-
DOI 10.1006/abio.1997.2392
-
Zhou M, Panchuck-Voloshina NA (1997) A one-step fluorimetric method for the continuous measurement of monoamine oxidase activity. Anal Biochem 253:169-174 (Pubitemid 27508168)
-
(1997)
Analytical Biochemistry
, vol.253
, Issue.2
, pp. 169-174
-
-
Zhou, M.1
Panchuk-Voloshina, N.2
|