-
1
-
-
33748612728
-
Uncompetitive antagonism of AMPA receptors: Mechanistic insights from studies of polyamine toxin derivatives
-
Andersen TF, Tikhonov DB, Bolcho U, Bolshakov K, Nelson JK, Pluteanu F, Mellor IR, Egebjerg J, Stromgaard K (2006) Uncompetitive antagonism of AMPA receptors: mechanistic insights from studies of polyamine toxin derivatives. J Med Chem 49 (18):5414-5423
-
(2006)
J. Med. Chem.
, vol.49
, Issue.18
, pp. 5414-5423
-
-
Andersen, T.F.1
Tikhonov, D.B.2
Bolcho, U.3
Bolshakov, K.4
Nelson, J.K.5
Pluteanu, F.6
Mellor, I.R.7
Egebjerg, J.8
Stromgaard, K.9
-
2
-
-
28444461786
-
Naturally occurring polyamines: Interaction with macromolecules
-
Bachrach U (2005) Naturally occurring polyamines: interaction with macromolecules. Curr Protein Pept Sci 6 (6):559-566
-
(2005)
Curr. Protein Pept. Sci.
, vol.6
, Issue.6
, pp. 559-566
-
-
Bachrach, U.1
-
3
-
-
0019959890
-
The actions of some esters of 4-hydroxyquinuclidine on guinea-pig ileum, atria and rat fundus strip
-
Barlow RB, Kitchen R (1982) The actions of some esters of 4-hydroxyquinuclidine on guinea-pig ileum, atria and rat fundus strip. Br J Pharmacol 77 (3):549-557
-
(1982)
Br. J. Pharmacol.
, vol.77
, Issue.3
, pp. 549-557
-
-
Barlow, R.B.1
Kitchen, R.2
-
4
-
-
0037298750
-
Beta-amyloid aggregation induced by human acetylcholinesterase: Inhibition studies
-
Bartolini M, Bertucci C, Cavrini V, Andrisano V (2003) Beta-amyloid aggregation induced by human acetylcholinesterase: inhibition studies. Biochem Pharmacol 65 (3):407-416
-
(2003)
Biochem. Pharmacol.
, vol.65
, Issue.3
, pp. 407-416
-
-
Bartolini, M.1
Bertucci, C.2
Cavrini, V.3
Andrisano, V.4
-
5
-
-
0018381173
-
Cardiac muscarinic blocking and atropinic blocking effects of a tetramine disulfide and alpha-adrenoceptor blocking activity
-
Benfey BG, Yong MS, Belleau B, Melchiorre C (1979) Cardiac muscarinic blocking and atropinic blocking effects of a tetramine disulfide and alpha-adrenoceptor blocking activity. Can J Physiol Pharmacol 57 (1):41-47
-
(1979)
Can. J. Physiol. Pharmacol.
, vol.57
, Issue.1
, pp. 41-47
-
-
Benfey, B.G.1
Yong, M.S.2
Belleau, B.3
Melchiorre, C.4
-
6
-
-
0019274478
-
Irreversible alpha adrenoceptor blocking effects and reversible muscarinic blocking and nicotinic blocking effects of tetramine disulfides on the heart
-
Benfey BG, Belleau B, Brasili L, Giannella M, Melchiorre C (1980) Irreversible alpha adrenoceptor blocking effects and reversible muscarinic blocking and nicotinic blocking effects of tetramine disulfides on the heart. Can J Physiol Pharmacol 58 (12):1477-1483
-
(1980)
Can. J. Physiol. Pharmacol.
, vol.58
, Issue.12
, pp. 1477-1483
-
-
Benfey, B.G.1
Belleau, B.2
Brasili, L.3
Giannella, M.4
Melchiorre, C.5
-
7
-
-
0035794150
-
Location of the polyamine binding site in the vestibule of the nicotinic acetylcholine receptor ion channel
-
Bixel MG, Weise C, Bolognesi ML, Rosini M, Brierly MJ, Mellor IR, Usherwood PN, Melchiorre C, Hucho F (2001) Location of the polyamine binding site in the vestibule of the nicotinic acetylcholine receptor ion channel. J Biol Chem 276 (9):6151-6160
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.9
, pp. 6151-6160
-
-
Bixel, M.G.1
Weise, C.2
Bolognesi, M.L.3
Rosini, M.4
Brierly, M.J.5
Mellor, I.R.6
Usherwood, P.N.7
Melchiorre, C.8
Hucho, F.9
-
8
-
-
0037130187
-
Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure
-
Bolognesi ML, Bixel MG, Marucci G, Bartolini M, Krauss M, Angeli P, Antonello A, Rosini M, Tumiatti V, Hucho F, Melchiorre C (2002) Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure. J Med Chem 45 (15):3286-3295
-
(2002)
J. Med. Chem.
, vol.45
, Issue.15
, pp. 3286-3295
-
-
Bolognesi, M.L.1
Bixel, M.G.2
Marucci, G.3
Bartolini, M.4
Krauss, M.5
Angeli, P.6
Antonello, A.7
Rosini, M.8
Tumiatti, V.9
Hucho, F.10
Melchiorre, C.11
-
9
-
-
34948904272
-
Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease
-
Bolognesi ML, Banzi R, Bartolini M, Cavalli A, Tarozzi A, Andrisano V, Minarini A, Rosini M, Tumiatti V, Bergamini C, Fato R, Lenaz G, Hrelia P, Cattaneo A, Recanatini M, Melchiorre C (2007) Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease. J Med Chem 50 (20):4882-4897
-
(2007)
J. Med. Chem.
, vol.50
, Issue.20
, pp. 4882-4897
-
-
Bolognesi, M.L.1
Banzi, R.2
Bartolini, M.3
Cavalli, A.4
Tarozzi, A.5
Andrisano, V.6
Minarini, A.7
Rosini, M.8
Tumiatti, V.9
Bergamini, C.10
Fato, R.11
Lenaz, G.12
Hrelia, P.13
Cattaneo, A.14
Recanatini, M.15
Melchiorre, C.16
-
10
-
-
0024560588
-
The molecular basis of muscarinic receptor diversity
-
Bonner TI (1989) The molecular basis of muscarinic receptor diversity. Trends Neurosc 12 (4):148-151
-
(1989)
Trends Neurosc
, vol.12
, Issue.4
, pp. 148-151
-
-
Bonner, T.I.1
-
11
-
-
34248228763
-
Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases
-
Casero RA Jr, Marton LJ (2007) Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases. Nat Rev Drug Discov 6 (5):373-390
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, Issue.5
, pp. 373-390
-
-
Casero Jr., R.A.1
Marton, L.J.2
-
12
-
-
68549101792
-
Recent advances in the development of polyamine analogues as antitumor agents
-
Casero RA, Woster PM (2009) Recent advances in the development of polyamine analogues as antitumor agents. J Med Chem 52 (15):4551-4573
-
(2009)
J. Med. Chem.
, vol.52
, Issue.15
, pp. 4551-4573
-
-
Casero, R.A.1
Woster, P.M.2
-
13
-
-
39149091398
-
Multi-target-directed ligands to combat neurodegenerative diseases
-
Cavalli A, Bolognesi ML, Minarini A, Rosini M, Tumiatti V, Recanatini M, Melchiorre C (2008) Multi-target-directed ligands to combat neurodegenerative diseases. J Med Chem 51 (3):347-372
-
(2008)
J. Med. Chem.
, vol.51
, Issue.3
, pp. 347-372
-
-
Cavalli, A.1
Bolognesi, M.L.2
Minarini, A.3
Rosini, M.4
Tumiatti, V.5
Recanatini, M.6
Melchiorre, C.7
-
14
-
-
0024472069
-
Structure-activity relationships and pharmacological profile of selective tricyclic antimuscarinics
-
Eberlein WG, Engel W, Mihm G, Rudolf K, Wetzel B, Entzeroth M, Mayer N, Doods HN (1989) Structure-activity relationships and pharmacological profile of selective tricyclic antimuscarinics. Trends Pharmacol Sci Suppl IV: 50-54
-
(1989)
Trends Pharmacol. Sci. Suppl.
, vol.4
, pp. 50-54
-
-
Eberlein, W.G.1
Engel, W.2
Mihm, G.3
Rudolf, K.4
Wetzel, B.5
Entzeroth, M.6
Mayer, N.7
Doods, H.N.8
-
15
-
-
0024040604
-
Structure and synthesis of a potent glutamate receptor antagonist in wasp venom
-
Eldefrawi AT, Eldefrawi ME, Konno K, Mansour NA, Nakanishi K, Oltz E, Usherwood PN (1988) Structure and synthesis of a potent glutamate receptor antagonist in wasp venom. Proc Natl Acad Sci USA 85 (13):4910-4913
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, Issue.13
, pp. 4910-4913
-
-
Eldefrawi, A.T.1
Eldefrawi, M.E.2
Konno, K.3
Mansour, N.A.4
Nakanishi, K.5
Oltz, E.6
Usherwood, P.N.7
-
16
-
-
46749118974
-
Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease
-
Fisher A (2008) Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease. Neurotherapeutics 5 (3):433-442
-
(2008)
Neurotherapeutics
, vol.5
, Issue.3
, pp. 433-442
-
-
Fisher, A.1
-
17
-
-
4944242891
-
Polyamines and cancer: Old molecules, new understanding
-
Gerner EW, Meyskens FL Jr (2004) Polyamines and cancer: old molecules, new understanding. Nat Rev Cancer 4 (10):781-792
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.10
, pp. 781-792
-
-
Gerner, E.W.1
Meyskens Jr., F.L.2
-
18
-
-
0024419883
-
The selectivity filter of a ligand-gated ion channel. The helix-M2 model of the ion channel of the nicotinic acetylcholine receptor
-
Hucho F, Hilgenfeld R (1989) The selectivity filter of a ligand-gated ion channel. The helix-M2 model of the ion channel of the nicotinic acetylcholine receptor. FEBS Lett 257 (1):17-23
-
(1989)
FEBS Lett.
, vol.257
, Issue.1
, pp. 17-23
-
-
Hucho, F.1
Hilgenfeld, R.2
-
19
-
-
0029863697
-
Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: Possible role of the peripheral site of the enzyme
-
Inestrosa NC, Alvarez A, Perez CA, Moreno RD, Vicente M, Linker C, Casanueva OI, Soto C, Garrido J (1996) Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron 16 (4):881-891
-
(1996)
Neuron
, vol.16
, Issue.4
, pp. 881-891
-
-
Inestrosa, N.C.1
Alvarez, A.2
Perez, C.A.3
Moreno, R.D.4
Vicente, M.5
Linker, C.6
Casanueva, O.I.7
Soto, C.8
Garrido, J.9
-
20
-
-
0032105387
-
Structure-function analysis of muscarinic acetylcholine receptors
-
Kostenis E, Zeng FY, Wess J (1998) Structure-function analysis of muscarinic acetylcholine receptors. J Phys 92 (3-4): 265-268
-
(1998)
J. Phys.
, vol.92
, Issue.3-4
, pp. 265-268
-
-
Kostenis, E.1
Zeng, F.Y.2
Wess, J.3
-
21
-
-
0023925110
-
Polymethylene tetramines: A new generation of selective muscarinic antagonists
-
Melchiorre C (1988) Polymethylene tetramines: a new generation of selective muscarinic antagonists. Trends Pharmacol Sci 9 (6):216-220
-
(1988)
Trends Pharmacol. Sci.
, vol.9
, Issue.6
, pp. 216-220
-
-
Melchiorre, C.1
-
22
-
-
0025367609
-
Polymethylene tetraamines: A novel class of cardioselective M2-antagonists
-
Melchiorre C (1990) Polymethylene tetraamines: a novel class of cardioselective M2-antagonists. Med Res Rev 10 (3):327-349
-
(1990)
Med. Res. Rev.
, vol.10
, Issue.3
, pp. 327-349
-
-
Melchiorre, C.1
-
23
-
-
0023068542
-
Differential blockade of muscarinic receptor subtypes by polymethylene tetraamines. Novel class of selective antagonists of cardiac M-2 muscarinic receptors
-
Melchiorre C, Cassinelli A, Quaglia W (1987) Differential blockade of muscarinic receptor subtypes by polymethylene tetraamines. Novel class of selective antagonists of cardiac M-2 muscarinic receptors. J Med Chem 30 (1):201-204
-
(1987)
J. Med. Chem.
, vol.30
, Issue.1
, pp. 201-204
-
-
Melchiorre, C.1
Cassinelli, A.2
Quaglia, W.3
-
24
-
-
0024472072
-
Polymethylene tetraamines as muscarinic receptor probes
-
Melchiorre C, Minarini A, Angeli P, Giardina D, Gulini U, Quaglia W (1989) Polymethylene tetraamines as muscarinic receptor probes. Trends Pharmacol Sci Suppl IV: 55-59
-
(1989)
Trends Pharmacol. Sci. Suppl.
, vol.4
, pp. 55-59
-
-
Melchiorre, C.1
Minarini, A.2
Angeli, P.3
Giardina, D.4
Gulini, U.5
Quaglia, W.6
-
25
-
-
0027133582
-
Synthesis and biological activity of some methoctramine-related tetraamines bearing a 11-acetyl-5, 11-dihydro-6H-pyr-ido[2, 3-b][1, 4]-benzodiazepin-6-one moiety as antimuscarinics: A second generation of highly selective M2 muscarinic receptor antagonists
-
Melchiorre C, Bolognesi ML, Chiarini A, Minarini A, Spampinato S (1993) Synthesis and biological activity of some methoctramine-related tetraamines bearing a 11-acetyl-5, 11-dihydro-6H-pyr-ido[2, 3-b][1, 4]-benzodiazepin-6-one moiety as antimuscarinics: a second generation of highly selective M2 muscarinic receptor antagonists. J Med Chem 36 (23):3734-3737
-
(1993)
J. Med. Chem.
, vol.36
, Issue.23
, pp. 3734-3737
-
-
Melchiorre, C.1
Bolognesi, M.L.2
Chiarini, A.3
Minarini, A.4
Spampinato, S.5
-
26
-
-
0028910769
-
Design, synthesis and biological-activity of some tetraamines related to methoctramine and 4-DAMP
-
Melchiorre C, Minarini A, Spampinato S, Tumiatti V (1995) Design, synthesis and biological-activity of some tetraamines related to methoctramine and 4-DAMP. Bioorg Med Chem Lett 5 (8):785-790
-
(1995)
Bioorg Med. Chem. Lett.
, vol.5
, Issue.8
, pp. 785-790
-
-
Melchiorre, C.1
Minarini, A.2
Spampinato, S.3
Tumiatti, V.4
-
27
-
-
0032561371
-
Acetylcholinesterase noncovalent inhibitors based on a poly-amine backbone for potential use against Alzheimer's disease
-
Melchiorre C, Andrisano V, Bolognesi ML, Budriesi R, Cavalli A, Cavrini V, Rosini M, Tumiatti V, Recanatini M (1998) Acetylcholinesterase noncovalent inhibitors based on a poly-amine backbone for potential use against Alzheimer's disease. J Med Chem 41 (22):4186-4189
-
(1998)
J. Med. Chem.
, vol.41
, Issue.22
, pp. 4186-4189
-
-
Melchiorre, C.1
Andrisano, V.2
Bolognesi, M.L.3
Budriesi, R.4
Cavalli, A.5
Cavrini, V.6
Rosini, M.7
Tumiatti, V.8
Recanatini, M.9
-
28
-
-
0037369134
-
Polymethylene tetraamine backbone as template for the development of biologically active polyamines
-
Melchiorre C, Antonello A, Banzi R, Bolognesi ML, Minarini A, Rosini M, Tumiatti V (2003) Polymethylene tetraamine backbone as template for the development of biologically active polyamines. Med Res Rev 23 (2):200-233
-
(2003)
Med. Res. Rev.
, vol.23
, Issue.2
, pp. 200-233
-
-
Melchiorre, C.1
Antonello, A.2
Banzi, R.3
Bolognesi, M.L.4
Minarini, A.5
Rosini, M.6
Tumiatti, V.7
-
29
-
-
8844234955
-
Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons
-
Mellor IR, Ogilvie J, Pluteanu F, Clothier RH, Parker TL, Rosini M, Minarini A, Tumiatti V, Melchiorre C (2004) Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons. Eur J Pharm 505 (1-3): 37-50
-
(2004)
Eur. J. Pharm.
, vol.505
, Issue.1-3
, pp. 37-50
-
-
Mellor, I.R.1
Ogilvie, J.2
Pluteanu, F.3
Clothier, R.H.4
Parker, T.L.5
Rosini, M.6
Minarini, A.7
Tumiatti, V.8
Melchiorre, C.9
-
30
-
-
0027945826
-
Design, synthesis, and biological activity of methoctramine-related tetraamines bearing an 11-acetyl-5, 11-dihydro-6H-pyrido[2, 3-b][1, 4] benzodiazepin-6-one moiety: Structural requirements for optimum occupancy of muscarinic receptor subtypes as revealed by symmetrical and unsymmetrical polyamines
-
Minarini A, Bolognesi ML, Budriesi R, Canossa M, Chiarini A, Cacciaguerra S (1994) Design, synthesis, and biological activity of methoctramine-related tetraamines bearing an 11-acetyl-5, 11-dihydro-6H-pyrido[2, 3-b][1, 4] benzodiazepin-6-one moiety: structural requirements for optimum occupancy of muscarinic receptor subtypes as revealed by symmetrical and unsymmetrical polyamines. J Med Chem 37 (20):3363-3372
-
(1994)
J. Med. Chem.
, vol.37
, Issue.20
, pp. 3363-3372
-
-
Minarini, A.1
Bolognesi, M.L.2
Budriesi, R.3
Canossa, M.4
Chiarini, A.5
Cacciaguerra, S.6
-
31
-
-
0030776090
-
Structure-binding relation of philanthotoxins from nicotinic acetylcholine receptor binding assay
-
Nakanishi K, Huang X, Jiang H, Liu Y, Fang K, Huang D, Choi SK, Katz E, Eldefrawi M (1997) Structure-binding relation of philanthotoxins from nicotinic acetylcholine receptor binding assay. Bioorg Med Chem 5 (10):1969-1988
-
(1997)
Bioorg Med. Chem.
, vol.5
, Issue.10
, pp. 1969-1988
-
-
Nakanishi, K.1
Huang, X.2
Jiang, H.3
Liu, Y.4
Fang, K.5
Huang, D.6
Choi, S.K.7
Katz, E.8
Eldefrawi, M.9
-
32
-
-
0028938451
-
Synthesis, muscarinic blocking activity and molecular modeling studies of 4-DAMP-related compounds
-
Recanatini M, Tumiatti V, Budriesi R, Chiarini A, Sabatino P, Bolognesi ML, Melchiorre C (1995) Synthesis, muscarinic blocking activity and molecular modeling studies of 4-DAMP-related compounds. Bioorg Med Chem 3 (3):267-277
-
(1995)
Bioorg Med. Chem.
, vol.3
, Issue.3
, pp. 267-277
-
-
Recanatini, M.1
Tumiatti, V.2
Budriesi, R.3
Chiarini, A.4
Sabatino, P.5
Bolognesi, M.L.6
Melchiorre, C.7
-
33
-
-
0033576672
-
Design, synthesis, and biological evaluation of symmetrically and unsymmetrically substituted methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists
-
Rosini M, Budriesi R, Bixel MG, Bolognesi ML, Chiarini A, Hucho F, Krogsgaard-Larsen P, Mellor IR, Minarini A, Tumiatti V, Usherwood PN, Melchiorre C (1999) Design, synthesis, and biological evaluation of symmetrically and unsymmetrically substituted methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. J Med Chem 42 (25):5212-5223
-
(1999)
J. Med. Chem.
, vol.42
, Issue.25
, pp. 5212-5223
-
-
Rosini, M.1
Budriesi, R.2
Bixel, M.G.3
Bolognesi, M.L.4
Chiarini, A.5
Hucho, F.6
Krogsgaard-Larsen, P.7
Mellor, I.R.8
Minarini, A.9
Tumiatti, V.10
Usherwood, P.N.11
Melchiorre, C.12
-
34
-
-
0037171738
-
Structure-activity relationships of methoctramine-related poly-amines as muscular nicotinic receptor noncompetitive antagonists. 2. Role of polymethylene chain lengths separating amine functions and of substituents on the terminal nitrogen atoms
-
Rosini M, Bixel MG, Marucci G, Budriesi R, Krauss M, Bolognesi ML, Minarini A, Tumiatti V, Hucho F, Melchiorre C (2002) Structure-activity relationships of methoctramine-related poly-amines as muscular nicotinic receptor noncompetitive antagonists. 2. Role of polymethylene chain lengths separating amine functions and of substituents on the terminal nitrogen atoms. J Med Chem 45 (9):1860-1878
-
(2002)
J. Med. Chem.
, vol.45
, Issue.9
, pp. 1860-1878
-
-
Rosini, M.1
Bixel, M.G.2
Marucci, G.3
Budriesi, R.4
Krauss, M.5
Bolognesi, M.L.6
Minarini, A.7
Tumiatti, V.8
Hucho, F.9
Melchiorre, C.10
-
35
-
-
0024533681
-
Allosteric inhibition of nicotinic acetylcholine receptors of vertebrates and insects by philanthotoxin
-
Rozental R, Scoble GT, Albuquerque EX, Idriss M, Sherby S, Sattelle DB, Nakanishi K, Konno K, Eldefrawi AT, Eldefrawi ME (1989) Allosteric inhibition of nicotinic acetylcholine receptors of vertebrates and insects by philanthotoxin. J Pharmacol Exp Ther 249 (1):123-130
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.249
, Issue.1
, pp. 123-130
-
-
Rozental, R.1
Scoble, G.T.2
Albuquerque, E.X.3
Idriss, M.4
Sherby, S.5
Sattelle, D.B.6
Nakanishi, K.7
Konno, K.8
Eldefrawi, A.T.9
Eldefrawi, M.E.10
-
36
-
-
40749160944
-
Disease-modifying therapies in Alzheimer's disease
-
Salloway S, Mintzer J, Weiner MF, Cummings JL (2008) Disease-modifying therapies in Alzheimer's disease. Alzheimers Dement 4 (2):65-79
-
(2008)
Alzheimers Dement
, vol.4
, Issue.2
, pp. 65-79
-
-
Salloway, S.1
Mintzer, J.2
Weiner, M.F.3
Cummings, J.L.4
-
37
-
-
0032561259
-
Spermine causes caspase activation in leukaemia cells
-
Stefanelli C, Bonavita F, Stanic I, Mignani M, Facchini A, Pignatti C, Flamigni F, Caldarera CM (1998) Spermine causes caspase activation in leukaemia cells. FEBS Lett 437 (3):233-236
-
(1998)
FEBS Lett.
, vol.437
, Issue.3
, pp. 233-236
-
-
Stefanelli, C.1
Bonavita, F.2
Stanic, I.3
Mignani, M.4
Facchini, A.5
Pignatti, C.6
Flamigni, F.7
Caldarera, C.M.8
-
38
-
-
1942495754
-
AMPA receptor ligands: Synthetic and pharmacological studies of polyamines and polyamine toxins
-
Stromgaard K, Mellor I (2004) AMPA receptor ligands: synthetic and pharmacological studies of polyamines and polyamine toxins. Med Res Rev 24 (5):589-620
-
(2004)
Med. Res. Rev.
, vol.24
, Issue.5
, pp. 589-620
-
-
Stromgaard, K.1
Mellor, I.2
-
39
-
-
15944411320
-
Polyamine toxins: Development of selective ligands for ionotropic receptors
-
Stromgaard K, Jensen LS, Vogensen SB (2005) Polyamine toxins: development of selective ligands for ionotropic receptors. Toxicon 45 (3):249-254
-
(2005)
Toxicon
, vol.45
, Issue.3
, pp. 249-254
-
-
Stromgaard, K.1
Jensen, L.S.2
Vogensen, S.B.3
-
40
-
-
35649027386
-
White matter NMDA receptors: An unexpected new therapeutic target?
-
Stys PK, Lipton SA (2007) White matter NMDA receptors: an unexpected new therapeutic target? Trends Pharmacol Sci 28 (11):561-566
-
(2007)
Trends Pharmacol. Sci.
, vol.28
, Issue.11
, pp. 561-566
-
-
Stys, P.K.1
Lipton, S.A.2
-
41
-
-
0035099627
-
Polyamines in cell growth and cell death: Molecular mechanisms and therapeutic applications
-
Thomas T, Thomas TJ (2001) Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell Mol Life Sci 58 (2):244-258
-
(2001)
Cell. Mol. Life Sci.
, vol.58
, Issue.2
, pp. 244-258
-
-
Thomas, T.1
Thomas, T.J.2
-
42
-
-
0037435051
-
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine
-
Tumiatti V, Rosini M, Bartolini M, Cavalli A, Marucci G, Andrisano V, Angeli P, Banzi R, Minarini A, Recanatini M, Melchiorre C (2003) Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine. J Med Chem 46 (6):954-966
-
(2003)
J. Med. Chem.
, vol.46
, Issue.6
, pp. 954-966
-
-
Tumiatti, V.1
Rosini, M.2
Bartolini, M.3
Cavalli, A.4
Marucci, G.5
Andrisano, V.6
Angeli, P.7
Banzi, R.8
Minarini, A.9
Recanatini, M.10
Melchiorre, C.11
-
43
-
-
10644228563
-
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a poly-amine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties
-
Tumiatti V, Andrisano V, Banzi R, Bartolini M, Minarini A, Rosini M, Melchiorre C (2004) Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a poly-amine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties. J Med Chem 47 (26):6490-6498
-
(2004)
J. Med. Chem.
, vol.47
, Issue.26
, pp. 6490-6498
-
-
Tumiatti, V.1
Andrisano, V.2
Banzi, R.3
Bartolini, M.4
Minarini, A.5
Rosini, M.6
Melchiorre, C.7
-
44
-
-
56749149563
-
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a poly-amine backbone. 4. Further investigation on the inner spacer
-
Tumiatti V, Milelli A, Minarini A, Rosini M, Bolognesi ML, Micco M, Andrisano V, Bartolini M, Mancini F, Recanatini M, Cavalli A, Melchiorre C (2008) Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a poly-amine backbone. 4. Further investigation on the inner spacer. J Med Chem 51 (22):7308-7312
-
(2008)
J. Med. Chem.
, vol.51
, Issue.22
, pp. 7308-7312
-
-
Tumiatti, V.1
Milelli, A.2
Minarini, A.3
Rosini, M.4
Bolognesi, M.L.5
Micco, M.6
Andrisano, V.7
Bartolini, M.8
Mancini, F.9
Recanatini, M.10
Cavalli, A.11
Melchiorre, C.12
-
45
-
-
34547651362
-
Polyamine analogues-an update
-
Wallace HM, Niiranen K (2007) Polyamine analogues-an update. Amino acids 33 (2):261-265
-
(2007)
Amino Acids
, vol.33
, Issue.2
, pp. 261-265
-
-
Wallace, H.M.1
Niiranen, K.2
-
46
-
-
0028907038
-
Muscarinic acetylcho-line receptors: Structural basis of ligand binding and G protein coupling
-
Wess J, Blin N, Mutschler E, Bluml K (1995) Muscarinic acetylcho-line receptors: structural basis of ligand binding and G protein coupling. Life Sci 56 (11-12): 915-922
-
(1995)
Life Sci.
, vol.56
, Issue.11-12
, pp. 915-922
-
-
Wess, J.1
Blin, N.2
Mutschler, E.3
Bluml, K.4
-
47
-
-
70249111805
-
Cytotoxicity of methoctramine and methoctramine-related polyamines
-
Zini M, Passariello CL, Gottardi D, Cetrullo S, Flamigni F, Pignatti C, Minarini A, Tumiatti V, Milelli A, Melchiorre C, Stefanelli C (2009) Cytotoxicity of methoctramine and methoctramine-related polyamines. Chem Biol Inter 181 (3):409-416
-
(2009)
Chem. Biol. Inter
, vol.181
, Issue.3
, pp. 409-416
-
-
Zini, M.1
Passariello, C.L.2
Gottardi, D.3
Cetrullo, S.4
Flamigni, F.5
Pignatti, C.6
Minarini, A.7
Tumiatti, V.8
Milelli, A.9
Melchiorre, C.10
Stefanelli, C.11
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