메뉴 건너뛰기




Volumn 42, Issue 2-3, 2012, Pages 1055-1064

Autoantibodies from patients with celiac disease inhibit transglutaminase 2 binding to heparin/heparan sulfate and interfere with intestinal epithelial cell adhesion

Author keywords

Adhesion; Autoantibodies; Caco 2 cells; Heparin heparan sulfate; Transglutaminase 2

Indexed keywords

ARGININE; ASPARTIC ACID; AUTOANTIBODY; FIBRONECTIN; GLYCINE; HEPARAN SULFATE; HEPARIN; IMMUNOGLOBULIN A ANTIBODY; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2 ANTIBODY; UNCLASSIFIED DRUG; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

EID: 84859630491     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-011-1020-1     Document Type: Article
Times cited : (14)

References (37)
  • 1
    • 0034695929 scopus 로고    scopus 로고
    • Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin
    • Akimov SS, Krylov D, Fleischman LF, Belkin AM (2000) Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin. J Cell Biol 148:825-838
    • (2000) J Cell Biol , vol.148 , pp. 825-838
    • Akimov, S.S.1    Krylov, D.2    Fleischman, L.F.3    Belkin, A.M.4
  • 2
    • 0037053359 scopus 로고    scopus 로고
    • Analysis of tissue transglutaminase function in the migration of Swiss 3T3 fibroblasts. The active-state conformation of the enzyme does not affect cell motility but is important for its secretion
    • DOI 10.1074/jbc.M109836200
    • Balklava Z, Verderio E, Collighan R, Gross S, Adams J, Griffin M (2002) Analysis of tissue transglutaminase function in the migration of Swiss 3T3 fibroblasts: the active-state conformation of the enzyme does not affect cell motility but is important for its secretion. J Biol Chem 277:16567-16575 (Pubitemid 34967673)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.19 , pp. 16567-16575
    • Balklava, Z.1    Verderio, E.2    Collighan, R.3    Gross, S.4    Adams, J.5    Griffin, M.6
  • 3
    • 34247269631 scopus 로고    scopus 로고
    • Humoral immune response to tissue transglutaminase is related to epithelial cell proliferation in celiac disease
    • DOI 10.1053/j.gastro.2007.01.030, PII S0016508507001655
    • Barone MV, Caputo I, Ribecco MT, Maglio M, Marzari R, Sblattero D, Troncone R, Auricchio S, Esposito C (2007) Humoral immune response to tissue transglutaminase is related to epithelial cell proliferation in celiac disease. Gastroenterology 132:1245-1253 (Pubitemid 46627567)
    • (2007) Gastroenterology , vol.132 , Issue.4 , pp. 1245-1253
    • Barone, M.V.1    Caputo, I.2    Ribecco, M.T.3    Maglio, M.4    Marzari, R.5    Sblattero, D.6    Troncone, R.7    Auricchio, S.8    Esposito, C.9
  • 4
    • 34247610845 scopus 로고    scopus 로고
    • Heparan sulphate proteoglycans fine-tune mammalian physiology
    • DOI 10.1038/nature05817, PII NATURE05817
    • Bishop JR, Schuksz M, Esko JD (2007) Heparan sulphate proteoglycans fine-tune mammalian physiology. Nature 446:1030-1037 (Pubitemid 46676065)
    • (2007) Nature , vol.446 , Issue.7139 , pp. 1030-1037
    • Bishop, J.R.1    Schuksz, M.2    Esko, J.D.3
  • 5
    • 77955271862 scopus 로고    scopus 로고
    • Coeliac disease autoantibodies mediate significant inhibition of tissue transglutaminase
    • Byrne G, Feighery C, Jackson J, Kelly J (2010) Coeliac disease autoantibodies mediate significant inhibition of tissue transglutaminase. Clin Immunol 136:426-431
    • (2010) Clin Immunol , vol.136 , pp. 426-431
    • Byrne, G.1    Feighery, C.2    Jackson, J.3    Kelly, J.4
  • 9
  • 10
    • 0242329754 scopus 로고    scopus 로고
    • Autoantibodies of patients with coeliac disease are insufficient to block tissue transglutaminase activity
    • DOI 10.1136/gut.52.11.1562
    • Dieterich W, Trapp D, Esslinger B, Leidenberger M, Piper J, Hahn E, Schuppan D (2003) Autoantibodies of patients with coeliac disease are insufficient to block tissue transglutaminase activity. Gut 52:1562-1566 (Pubitemid 37363438)
    • (2003) Gut , vol.52 , Issue.11 , pp. 1562-1566
    • Dieterich, W.1    Trapp, D.2    Esslinger, B.3    Leidenberger, M.4    Piper, J.5    Hahn, E.6    Schuppan, D.7
  • 11
    • 0036073617 scopus 로고    scopus 로고
    • Anti-tissue transglutaminase antibodies from coeliac patients inhibit transglutaminase activity both in vitro and in situ
    • DOI 10.1136/gut.51.2.177
    • Esposito C, Paparo F, Caputo I, Rossi M, Maglio M, Sblattero D, Not T, Porta R, Auricchio S, Marzari R, Troncone R (2002) Antitissue transglutaminase antibodies from coeliac patients inhibit transglutaminase activity both in vitro and in situ. Gut 51:177-181 (Pubitemid 34791442)
    • (2002) Gut , vol.51 , Issue.2 , pp. 177-181
    • Esposito, C.1    Paparo, F.2    Caputo, I.3    Rossi, M.4    Maglio, M.5    Sblattero, D.6    Not, T.7    Porta, R.8    Auricchio, S.9    Marzari, R.10    Troncone, R.11
  • 12
    • 0033011434 scopus 로고    scopus 로고
    • Serum immunoglobulin A from patients with celiac disease inhibits human T84 intestinal crypt epithelial cell differentiation
    • Halttunen T, Maki M (1999) Serum immunoglobulin A from patients with celiac disease inhibits human T84 intestinal crypt epithelial cell differentiation. Gastroenterology 116:566-572 (Pubitemid 29106764)
    • (1999) Gastroenterology , vol.116 , Issue.3 , pp. 566-572
    • Halttunen, T.1    Maki, M.2
  • 13
    • 21244479796 scopus 로고    scopus 로고
    • 2-terminal β-sandwich domain of tissue transglutaminase
    • DOI 10.1074/jbc.M503323200
    • Hang J, Zemskov EA, Lorand L, Belkin AM (2005) Identification of a novel recognition sequence for fibronectin within the NH2- terminal beta-sandwich domain of tissue transglutaminase. J Biol Chem 280:23675-23683 (Pubitemid 40884849)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.25 , pp. 23675-23683
    • Hang, J.1    Zemskov, E.A.2    Lorand, L.3    Belkin, A.M.4
  • 14
    • 67651071286 scopus 로고    scopus 로고
    • Transglutaminases and disease: Lessons from genetically engineered mouse models and inherited disorders
    • Iismaa SE, Mearns BM, Lorand L, Graham RM (2009) Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders. Physiol Rev 89:991-1023
    • (2009) Physiol Rev , vol.89 , pp. 991-1023
    • Iismaa, S.E.1    Mearns, B.M.2    Lorand, L.3    Graham, R.M.4
  • 15
    • 72949102295 scopus 로고    scopus 로고
    • Tissue-mediated control of immunopathology in coeliac disease
    • Jabri B, Sollid LM (2009) Tissue-mediated control of immunopathology in coeliac disease. Nat Rev Immunol 9:858-870
    • (2009) Nat Rev Immunol , vol.9 , pp. 858-870
    • Jabri, B.1    Sollid, L.M.2
  • 16
    • 0036136848 scopus 로고    scopus 로고
    • Blisters in the small intestinal mucosa of coeliac patients contain t cells positive for cyclooxygenase 2
    • DOI 10.1136/gut.0500084..
    • Kainulainen H, Rantala I, Collin P, Ruuska T, Paivarinne H, Halttunen T, Lindfors K, Kaukinen K, Maki M (2002) Blisters in the small intestinal mucosa of coeliac patients contain T cells positive for cyclooxygenase 2. Gut 50:84-89 (Pubitemid 34028308)
    • (2002) Gut , vol.50 , Issue.1 , pp. 84-89
    • Kainulainen, H.1    Rantala, I.2    Collin, P.3    Ruuska, T.4    Paivarinne, H.5    Halttunen, T.6    Lindfors, K.7    Kaukinen, K.8    Maki, M.9
  • 17
    • 33744505628 scopus 로고    scopus 로고
    • Coeliac autoantibodies can enhance transamidating and inhibit GTPase activity of tissue transglutaminase: Dependence on reaction environment and enzyme fitness
    • DOI 10.1016/j.jaut.2006.03.002, PII S0896841106000175
    • Kiraly R, Vecsei Z, Demenyi T, Korponay-Szabo IR, Fesus L (2006) Coeliac autoantibodies can enhance transamidating and inhibit GTPase activity of tissue transglutaminase: dependence on reaction environment and enzyme fitness. J Autoimmun 26:278-287 (Pubitemid 43817486)
    • (2006) Journal of Autoimmunity , vol.26 , Issue.4 , pp. 278-287
    • Kiraly, R.1    Vecsei, Z.2    Demenyi, T.3    Korponay-Szabo, I.R.4    Fesus, L.5
  • 18
    • 2342426804 scopus 로고    scopus 로고
    • In vivo targeting of intestinal and extraintestinal transglutaminase 2 by coeliac autoantibodies
    • DOI 10.1136/gut.2003.024836
    • Korponay-Szabo IR, Halttunen T, Szalai Z, Laurila K, Kiraly R, Kovacs JB, Fesus L, Maki M (2004) In vivo targeting of intestinal and extraintestinal transglutaminase 2 by coeliac autoantibodies. Gut 53:641-648 (Pubitemid 38561440)
    • (2004) Gut , vol.53 , Issue.5 , pp. 641-648
    • Korponay-Szabo, I.R.1    Halttunen, T.2    Szalai, Z.3    Laurila, K.4    Kiraly, R.5    Kovacs, J.B.6    Fesus, L.7    Mki, M.8
  • 19
    • 33745135043 scopus 로고    scopus 로고
    • Systematic review: The use of serology to exclude or diagnose coeliac disease (a comparison of the endomysial and tissue transglutaminase antibody tests)
    • DOI 10.1111/j.1365-2036.2006.02967.x
    • Lewis NR, Scott BB (2006) Systematic review: the use of serology to exclude or diagnose coeliac disease (a comparison of the endomysial and tissue transglutaminase antibody tests). Aliment Pharmacol Ther 24:47-54 (Pubitemid 43894004)
    • (2006) Alimentary Pharmacology and Therapeutics , vol.24 , Issue.1 , pp. 47-54
    • Lewis, N.R.1    Scott, B.B.2
  • 20
    • 62949125263 scopus 로고    scopus 로고
    • A role for anti-transglutaminase 2 autoantibodies in the pathogenesis of coeliac disease?
    • Lindfors K, Kaukinen K, Maki M (2009) A role for anti-transglutaminase 2 autoantibodies in the pathogenesis of coeliac disease? Amino Acids 36:685-691
    • (2009) Amino Acids , vol.36 , pp. 685-691
    • Lindfors, K.1    Kaukinen, K.2    Maki, M.3
  • 21
    • 0037022619 scopus 로고    scopus 로고
    • Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity
    • DOI 10.1073/pnas.042454899
    • Liu S, Cerione RA, Clardy J (2002) Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity. Proc Natl Acad Sci USA 99:2743-2747 (Pubitemid 34240531)
    • (2002) Proceedings of the National Academy of Sciences of the United States of America , vol.99 , Issue.5 , pp. 2743-2747
    • Liu, S.1    Cerione, R.A.2    Clardy, J.3
  • 22
    • 0037317032 scopus 로고    scopus 로고
    • Transglutaminases: Crosslinking enzymes with pleiotropic functions
    • DOI 10.1038/nrm1014
    • Lorand L, Graham RM (2003) Transglutaminases: crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol 4:140-156 (Pubitemid 36172696)
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , Issue.2 , pp. 140-156
    • Lorand, L.1    Graham, R.M.2
  • 24
    • 78049427740 scopus 로고    scopus 로고
    • Transglutaminase 2: A multitasking protein in the complex circuitry of inflammation and cancer
    • Mehta K, Kumar A, Kim HI (2010) Transglutaminase 2: a multitasking protein in the complex circuitry of inflammation and cancer. Biochem Pharmacol 80:1921-1929
    • (2010) Biochem Pharmacol , vol.80 , pp. 1921-1929
    • Mehta, K.1    Kumar, A.2    Kim, H.I.3
  • 27
    • 38549156658 scopus 로고    scopus 로고
    • Transglutaminase 2 undergoes a large conformational change upon activation
    • Pinkas DM, Strop P, Brunger AT, Khosla C (2007) Transglutaminase 2 undergoes a large conformational change upon activation. PLoS Biol 5:e327
    • (2007) PLoS Biol , vol.5
    • Pinkas, D.M.1    Strop, P.2    Brunger, A.T.3    Khosla, C.4
  • 28
    • 0029775681 scopus 로고    scopus 로고
    • RGD and other recognition sequences for integrins
    • DOI 10.1146/annurev.cellbio.12.1.697
    • Ruoslahti E (1996) RGD and other recognition sequences for integrins. Annu Rev Cell Dev Biol 12:697-715 (Pubitemid 26422728)
    • (1996) Annual Review of Cell and Developmental Biology , vol.12 , pp. 697-715
    • Ruoslahti, E.1
  • 29
    • 67650513329 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans are receptors for the cell-surface trafficking and biological activity of transglutaminase-2
    • Scarpellini A, Germack R, Lortat-Jacob H, Muramatsu T, Billett E, Johnson T, Verderio EA (2009) Heparan sulfate proteoglycans are receptors for the cell-surface trafficking and biological activity of transglutaminase-2. J Biol Chem 284:18411-18423
    • (2009) J Biol Chem , vol.284 , pp. 18411-18423
    • Scarpellini, A.1    Germack, R.2    Lortat-Jacob, H.3    Muramatsu, T.4    Billett, E.5    Johnson, T.6    Verderio, E.A.7
  • 31
    • 64849087024 scopus 로고    scopus 로고
    • A modified ELISA for improved detection of IgA, IgG, and IgM anti-tissue transglutaminase antibodies in celiac disease
    • Teesalu K, Agardh D, Panarina M, Utt M, Uibo O, Uibo R (2009) A modified ELISA for improved detection of IgA, IgG, and IgM anti-tissue transglutaminase antibodies in celiac disease. Clin Chim Acta 403:37-41
    • (2009) Clin Chim Acta , vol.403 , pp. 37-41
    • Teesalu, K.1    Agardh, D.2    Panarina, M.3    Utt, M.4    Uibo, O.5    Uibo, R.6
  • 32
    • 51049089580 scopus 로고    scopus 로고
    • Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling
    • Telci D, Wang Z, Li X, Verderio EA, Humphries MJ, Baccarini M, Basaga H, Griffin M (2008) Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling. J Biol Chem 283:20937-20947
    • (2008) J Biol Chem , vol.283 , pp. 20937-20947
    • Telci, D.1    Wang, Z.2    Li, X.3    Verderio, E.A.4    Humphries, M.J.5    Baccarini, M.6    Basaga, H.7    Griffin, M.8
  • 34
    • 0142242157 scopus 로고    scopus 로고
    • A novel RGD-independent cell adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis
    • DOI 10.1074/jbc.M303303200
    • Verderio EA, Telci D, Okoye A, Melino G, Griffin M (2003) A novel RGD-independent cell adhesion pathway mediated by fibronectin- bound tissue transglutaminase rescues cells from anoikis. J Biol Chem 278:42604-42614 (Pubitemid 37310534)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.43 , pp. 42604-42614
    • Verderio, E.A.M.1    Telci, D.2    Okoye, A.3    Melino, G.4    Griffin, M.5
  • 35
    • 62949246706 scopus 로고    scopus 로고
    • Novel interactions of TG2 with heparan sulfate proteoglycans: Reflection on physiological implications
    • Verderio EA, Scarpellini A, Johnson TS (2009) Novel interactions of TG2 with heparan sulfate proteoglycans: reflection on physiological implications. Amino Acids 36:671-677
    • (2009) Amino Acids , vol.36 , pp. 671-677
    • Verderio, E.A.1    Scarpellini, A.2    Johnson, T.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.