Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 733, Issue 1-2, 2012, Pages 21-33

  Fenech, Michael ^a  

^a CSIRO   (Australia)

Author keywords

Chromosome aberrations; DNA methylation; Folate; Folic acid; Genome; Homocysteine; Integrity; Micronuclei; Mitochondrial DNA; Recommended daily allowance; Telomere; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; DEOXYURIDINE PHOSPHATE; DNA; FOLIC ACID; HOMOCYSTEINE; METHIONINE SYNTHASE; MITOCHONDRIAL DNA; S ADENOSYLMETHIONINE; THYMIDINE PHOSPHATE; URACIL;

ALCOHOLISM; AMINO ACID BLOOD LEVEL; CELL NUCLEUS; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CHROMOSOME FRAGILE SITE; CULTURE MEDIUM; CYANOCOBALAMIN DEFICIENCY; CYTOKINESIS; DIET SUPPLEMENTATION; DIETARY REFERENCE INTAKE; DISEASE ASSOCIATION; DNA DAMAGE; DNA METABOLISM; DNA METHYLATION; ENZYME ACTIVITY; EPIGENETICS; FOLIC ACID DEFICIENCY; FOOD FREQUENCY QUESTIONNAIRE; GENE DELETION; GENE MUTATION; GENETIC VARIABILITY; GENOMIC INSTABILITY; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTESTINE ABSORPTION; IONIZING RADIATION; MICRONUCLEUS; MITOCHONDRIAL GENETICS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RADIATION EXPOSURE; REVIEW; TELOMERE SHORTENING; VITAMIN BLOOD LEVEL; VITAMIN METABOLISM;

ANIMALS; CELLS, CULTURED; DIETARY SUPPLEMENTS; DNA DAMAGE; DNA METHYLATION; FOLIC ACID; FOLIC ACID DEFICIENCY; GENE-ENVIRONMENT INTERACTION; GENOME, MITOCHONDRIAL; GENOMIC INSTABILITY; HUMANS; NUTRITIONAL REQUIREMENTS; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

EID: 84860545260     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2011.11.003     Document Type: Review

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