Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 22, 1999, Pages 12810-12815

  Skibola, Christine F ^a   Smith, Martyn T ^a   Kane, Eleanor ^b   Roman, Eve ^b   Rollinson, Sara ^c   Cartwright, Raymond A ^b   Morgan, Gareth ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Leukaemia Res Fund Ctr Clin E   (United Kingdom)

^c UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CELL DNA; METHYLENETETRAHYDROFOLIC ACID;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DNA DETERMINATION; ENZYME ACTIVITY; FOLATE METABOLISM; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMOGENESIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK ASSESSMENT;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; BASE SEQUENCE; DNA PRIMERS; FEMALE; GENOTYPE; HUMANS; LEUKEMIA; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; POLYMORPHISM, GENETIC;

EID: 0033607241     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.22.12810     Document Type: Article

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