Folate deficiency increases mtDNA and D-1 mtDNA deletion in aged brain of mice lacking uracil-DNA glycosylase

Experimental Neurology

Volumn 228, Issue 2, 2011, Pages 253-258

  Kronenberg, Golo ^a   Gertz, Karen ^a   Overall, Rupert W ^b   Harms, Christoph ^a   Klein, Jeanette ^a   Page, Melissa M ^c   Stuart, Jeffrey A ^c   Endres, Matthias ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^c BROCK UNIVERSITY   (Canada)

Author keywords

DNA repair; Folate; Mitochondrial DNA; Mitochondrial DNA deletion; Neurodegeneration; Uracil

Indexed keywords

CITRATE SYNTHASE; LACTATE DEHYDROGENASE; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; URACIL; URACIL DNA GLYCOSIDASE;

AGED; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; EXCISION REPAIR; FOLIC ACID DEFICIENCY; GENE DELETION; GENOTYPE; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

EID: 79952702673     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.01.014     Document Type: Article

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