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Volumn 349, Issue 1-2, 2011, Pages 159-167

Aberrations in one-carbon metabolism induce oxidative DNA damage in sporadic breast cancer

Author keywords

8 oxo 2 deoxyguanosine; Dietary micronutrients; One carbon metabolism; Polymorphisms; Sporadic breast cancer

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ESTRADIOL; FOLIC ACID; GLUTATHIONE; GLYCINE HYDROXYMETHYLTRANSFERASE; HOMOCYSTEINE;

EID: 79952281669     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0670-8     Document Type: Article
Times cited : (49)

References (46)
  • 1
    • 0037972270 scopus 로고    scopus 로고
    • DNA damage and breast cancer risk
    • DOI 10.1093/carcin/bgg037
    • TR Smith MS Miller KK Lohman LD Case JJ Hu 2003 DNA damage and breast cancer risk Carcinogenesis 24 5 883 889 1:CAS:528:DC%2BD3sXkt1Wrsb8%3D 10.1093/carcin/bgg037 12771032 (Pubitemid 36748904)
    • (2003) Carcinogenesis , vol.24 , Issue.5 , pp. 883-889
    • Smith, T.R.1    Miller, M.S.2    Lohman, K.K.3    Case, L.D.4    Hu, J.J.5
  • 2
    • 34547778505 scopus 로고    scopus 로고
    • Polymorphisms of one-carbon-metabolizing genes and risk of breast cancer in a population-based study
    • DOI 10.1093/carcin/bgm061
    • X Xu MD Gammon H Zhang JG Wetmur M Rao SL Teitelbaum JA Britton AI Neugut RM Santella J Chen 2007 Polymorphisms of one-carbon-metabolizing genes and risk of breast cancer in a population-based study Carcinogenesis 28 7 1504 1509 1:CAS:528:DC%2BD2sXos12jurs%3D 10.1093/carcin/bgm061 17372271 (Pubitemid 47241800)
    • (2007) Carcinogenesis , vol.28 , Issue.7 , pp. 1504-1509
    • Xu, X.1    Gammon, M.D.2    Zhang, H.3    Wetmur, J.G.4    Rao, M.5    Teitelbaum, S.L.6    Britton, J.A.7    Neugut, A.I.8    Santella, R.M.9    Chen, J.10
  • 3
    • 0034531005 scopus 로고    scopus 로고
    • Oxidants and antioxidants in breast cancer
    • CB Ambrosone 2000 Oxidants and antioxidants in breast cancer Antioxid Redox Signal 2 903 917 1:CAS:528:DC%2BD3MXlvFyntQ%3D%3D 10.1089/ars.2000.2.4-903 11213491 (Pubitemid 32062336)
    • (2000) Antioxidants and Redox Signaling , vol.2 , Issue.4 , pp. 903-917
    • Ambrosone, C.B.1
  • 4
    • 0028900690 scopus 로고
    • Persistent oxidative stress in cancer
    • 1:CAS:528:DyaK2MXjsFanur4%3D 10.1016/0014-5793(94)01368-B 7821417
    • S Toyokuni K Okamoto J Yodoi H Hiai 1995 Persistent oxidative stress in cancer FEBS Lett 358 1 3 1:CAS:528:DyaK2MXjsFanur4%3D 10.1016/0014-5793(94) 01368-B 7821417
    • (1995) FEBS Lett , vol.358 , pp. 1-3
    • Toyokuni, S.1    Okamoto, K.2    Yodoi, J.3    Hiai, H.4
  • 7
    • 67650489669 scopus 로고    scopus 로고
    • Folic acid or combination of folic acid and vitamin B(12) prevents short-term arsenic trioxide-induced systemic and mitochondrial dysfunction and DNA damage
    • 1:CAS:528:DC%2BD1MXotFCiu78%3D 10.1002/tox.20442 18825727
    • S Majumdar S Mukherjee A Maiti S Karmakar AS Das M Mukherjee A Nanda C Mitra 2009 Folic acid or combination of folic acid and vitamin B(12) prevents short-term arsenic trioxide-induced systemic and mitochondrial dysfunction and DNA damage Environ Toxicol 24 4 377 387 1:CAS:528:DC%2BD1MXotFCiu78%3D 10.1002/tox.20442 18825727
    • (2009) Environ Toxicol , vol.24 , Issue.4 , pp. 377-387
    • Majumdar, S.1    Mukherjee, S.2    Maiti, A.3    Karmakar, S.4    Das, A.S.5    Mukherjee, M.6    Nanda, A.7    Mitra, C.8
  • 8
    • 53149105108 scopus 로고    scopus 로고
    • Induction of oxidative stress and DNA damage in rat brain by a folate/methyl-deficient diet
    • 1:CAS:528:DC%2BD1cXht1SisLjN 10.1016/j.brainres.2008.07.073 18694737
    • TV Bagnyukova CL Powell O Pavliv VP Tryndyak IP Pogribny 2008 Induction of oxidative stress and DNA damage in rat brain by a folate/methyl-deficient diet Brain Res 1237 44 51 1:CAS:528:DC%2BD1cXht1SisLjN 10.1016/j.brainres.2008. 07.073 18694737
    • (2008) Brain Res , vol.1237 , pp. 44-51
    • Bagnyukova, T.V.1    Powell, C.L.2    Pavliv, O.3    Tryndyak, V.P.4    Pogribny, I.P.5
  • 9
    • 33747262660 scopus 로고    scopus 로고
    • Homocysteine stimulates phosphorylation of NADPH oxidase p47phox and p67phox subunits in monocytes via protein kinase Cβ activation
    • 1:CAS:528:DC%2BD28XnsFWqtrc%3D 10.1042/BJ20051810 16626305
    • YL Siow KKW Au-Yeung CWH Woo O Karmin 2006 Homocysteine stimulates phosphorylation of NADPH oxidase p47phox and p67phox subunits in monocytes via protein kinase Cβ activation Biochem J 398 73 82 1:CAS:528: DC%2BD28XnsFWqtrc%3D 10.1042/BJ20051810 16626305
    • (2006) Biochem J , vol.398 , pp. 73-82
    • Siow, Y.L.1    Au-Yeung, K.K.W.2    Woo, C.W.H.3    Karmin, O.4
  • 10
    • 77954544440 scopus 로고    scopus 로고
    • S-adenosylmethionine prevents oxidative stress and modulates glutathione metabolism in TgCRND8 mice fed a B-vitamin deficient diet
    • 1:CAS:528:DC%2BC3cXovFKgtrg%3D 20413874
    • RA Cavallaro A Fuso V Nicolia S Scarpa 2010 S-adenosylmethionine prevents oxidative stress and modulates glutathione metabolism in TgCRND8 mice fed a B-vitamin deficient diet J Alzheimers Dis 20 4 997 1002 1:CAS:528: DC%2BC3cXovFKgtrg%3D 20413874
    • (2010) J Alzheimers Dis , vol.20 , Issue.4 , pp. 997-1002
    • Cavallaro, R.A.1    Fuso, A.2    Nicolia, V.3    Scarpa, S.4
  • 11
    • 0034142268 scopus 로고    scopus 로고
    • Insights into the functions of BRCA1 and BRCA2
    • DOI 10.1016/S0168-9525(99)01930-7, PII S0168952599019307
    • PL Welcsh KN Owens MC King 2000 Insights into the functions of BRCA1 and BRCA2 Trends Genet 16 2 69 74 1:CAS:528:DC%2BD3cXpsFGqtg%3D%3D 10.1016/S0168-9525(99)01930-7 10652533 (Pubitemid 30084719)
    • (2000) Trends in Genetics , vol.16 , Issue.2 , pp. 69-74
    • Welcsh, P.L.1    Owens, K.N.2    King, M.-C.3
  • 12
    • 7444271583 scopus 로고    scopus 로고
    • BRCA1 induces antioxidant gene expression and resistance to oxidative stress
    • DOI 10.1158/0008-5472.CAN-04-1119
    • I Bae S Fan Q Meng JK Rih HJ Kim HJ Kang J Xu ID Goldberg AK Jaiswal EM Rosen 2004 BRCA1 induces antioxidant gene expression and resistance to oxidative stress Cancer Res 64 21 7893 7909 1:CAS:528:DC%2BD2cXptFelsrs%3D 10.1158/0008-5472.CAN-04-1119 15520196 (Pubitemid 39446923)
    • (2004) Cancer Research , vol.64 , Issue.21 , pp. 7893-7909
    • Bae, I.1    Fan, S.2    Meng, Q.3    Jeong, K.R.4    Hee, J.K.5    Hyo, J.K.6    Xu, J.7    Goldberg, I.D.8    Jaiswal, A.K.9    Rosen, E.M.10
  • 13
    • 0034703861 scopus 로고    scopus 로고
    • Glutamate carboxypeptidase II: A polymorphism associated with lower levels of serum folate and hyperhomocysteinemia
    • 1:CAS:528:DC%2BD3cXoslWmsLw%3D 10.1093/hmg/9.19.2837 11092759
    • AM Devlin EH Ling JM Peerson S Fernando R Clarke AD Smith CH Halsted 2000 Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia Hum Mol Genet 9 19 2837 2844 1:CAS:528:DC%2BD3cXoslWmsLw%3D 10.1093/hmg/9.19.2837 11092759
    • (2000) Hum Mol Genet , vol.9 , Issue.19 , pp. 2837-2844
    • Devlin, A.M.1    Ling, E.H.2    Peerson, J.M.3    Fernando, S.4    Clarke, R.5    Smith, A.D.6    Halsted, C.H.7
  • 14
    • 0033805360 scopus 로고    scopus 로고
    • A polymorphism (80 G- ≥a) in the reduced folate carrier gene and its associations with folate status and hyperhomocysteinemia
    • 1:CAS:528:DC%2BD3cXmsFemurc%3D 10.1006/mgme.2000.3034 10993718
    • A Chango N Emery-Fillon GP de Courcy D Lambert M Pfister DS Rosenblatt JP Nicolas 2000 A polymorphism (80 G- ≥A) in the reduced folate carrier gene and its associations with folate status and hyperhomocysteinemia Mol Genet Metab 70 310 315 1:CAS:528:DC%2BD3cXmsFemurc%3D 10.1006/mgme.2000.3034 10993718
    • (2000) Mol Genet Metab , vol.70 , pp. 310-315
    • Chango, A.1    Emery-Fillon, N.2    De Courcy, G.P.3    Lambert, D.4    Pfister, M.5    Rosenblatt, D.S.6    Nicolas, J.P.7
  • 15
    • 0032515921 scopus 로고    scopus 로고
    • Molecular cloning, characterization and alternative splicing of the human cytoplasmic serine hydroxymethyltransferase gene
    • DOI 10.1016/S0378-1119(98)00085-7, PII S0378111998000857
    • S Girgis IM Nasrallah JR Suh E Oppenheim KA Zanetti MG Mastri PJ Stover 1998 Molecular cloning, characterization and alternative splicing of the human cytoplasmic serine hydroxymethyltransferase gene Gene 210 2 315 324 1:CAS:528:DyaK1cXis1CmsL0%3D 10.1016/S0378-1119(98)00085-7 9573390 (Pubitemid 28171454)
    • (1998) Gene , vol.210 , Issue.2 , pp. 315-324
    • Girgis, S.1    Nasrallah, I.M.2    Suh, J.R.3    Oppenheim, E.4    Zanetti, K.A.5    Mastri, M.G.6    Stover, P.J.7
  • 16
    • 0035671827 scopus 로고    scopus 로고
    • Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression
    • K Kawakami D Salonga JM Park KD Danenberg H Uetake J Brabender K Omura G Watanabe PV Danenberg 2001 Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression Clin Cancer Res 7 12 4096 4101 1:CAS:528:DC%2BD38XltFShsg%3D%3D 11751507 (Pubitemid 34044633)
    • (2001) Clinical Cancer Research , vol.7 , Issue.12 , pp. 4096-4101
    • Kawakami, K.1    Salonga, D.2    Park, J.M.3    Danenberg, K.D.4    Uetake, H.5    Brabender, J.6    Omura, K.7    Watanabe, G.8    Danenberg, P.V.9
  • 17
    • 0034518362 scopus 로고    scopus 로고
    • Searching expressed sequence tag databases: Discovery and confirmation of a common polymorphism in the thymidylate synthase gene
    • CM Ulrich J Bigler CM Velicer EA Greene FM Farin JD Potter 2000 Searching expressed sequence tag databases: discovery and confirmation of a common polymorphism in the thymidylate synthase gene Cancer Epidemiol Biomarkers Prev 9 1381 1385 1:CAS:528:DC%2BD3MXktFahsg%3D%3D 11142426 (Pubitemid 32044809)
    • (2000) Cancer Epidemiology Biomarkers and Prevention , vol.9 , Issue.12 , pp. 1381-1385
    • Ulrich, C.M.1    Bigler, J.2    Velicer, C.M.3    Greene, E.A.4    Farin, F.M.5    Potter, J.D.6
  • 22
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • 1:CAS:528:DyaG1MXotl2ksA%3D%3D 10.1016/0003-9861(59)90090-6 13650640
    • GL Ellman 1959 Tissue sulfhydryl groups Arch Biochem Biophys 82 1 70 77 1:CAS:528:DyaG1MXotl2ksA%3D%3D 10.1016/0003-9861(59)90090-6 13650640
    • (1959) Arch Biochem Biophys , vol.82 , Issue.1 , pp. 70-77
    • Ellman, G.L.1
  • 23
    • 79952282910 scopus 로고    scopus 로고
    • Interactions of 5′-UTR thymidylate synthase polymorphism with 677C→ T methylene tetrahydrofolate reductase and 66A→ G methyltetrahydrofolate homocysteine methyl-transferase reductase polymorphisms determine susceptibility to coronary artery disease
    • Epub (PMID: 20962453)
    • Lakshmi VS, Naushad SM, Rupasree Y, Rao SD, Kutala1 VK (2010) Interactions of 5′-UTR thymidylate synthase polymorphism with 677C→ T methylene tetrahydrofolate reductase and 66A→ G methyltetrahydrofolate homocysteine methyl-transferase reductase polymorphisms determine susceptibility to coronary artery disease. J Atheroscler Thromb, Epub (PMID: 20962453)
    • (2010) J Atheroscler Thromb
    • Lakshmi, V.S.1    Naushad, S.M.2    Rupasree, Y.3    Rao, S.D.4    Kutalal, V.K.5
  • 24
    • 0031873791 scopus 로고    scopus 로고
    • Optimized procedure for DNA isolation from fresh and cryopreserved clotted human blood useful in clinical molecular testing
    • LA Salazar MH Hirata SA Cavalli MO Machado RD Hirata 1998 Optimized procedure for DNA isolation from fresh and cryopreserved clotted human blood useful in clinical molecular testing Clin Chem 44 8 Pt 1 1748 1750 1:CAS:528:DyaK1cXltleksro%3D 9702967 (Pubitemid 28381222)
    • (1998) Clinical Chemistry , vol.44 , Issue.8 , pp. 1748-1750
    • Salazar, L.A.1    Hirata, M.H.2    Cavalli, S.A.3    Machado, M.O.4    Hirata, R.D.C.5
  • 25
    • 84886588424 scopus 로고    scopus 로고
    • Kutala. Oxidative stress is associated with genetic polymorphisms in one-carbon metabolism in coronary artery disease
    • in press
    • Vijay Lakshmi SV, Naushad SM, Roopa Y, Seshagiri Rao D, Vijay K. Kutala. Oxidative stress is associated with genetic polymorphisms in one-carbon metabolism in coronary artery disease. Cell Biochem Biophys (in press)
    • Cell Biochem Biophys
    • Vijay Lakshmi, S.V.1    Naushad, S.M.2    Roopa, Y.3    Seshagiri Rao, D.4    Vijay, K.5
  • 26
  • 27
    • 1242269326 scopus 로고    scopus 로고
    • MTHFR Polymorphisms, Dietary Folate Intake, and Breast Cancer Risk: Results from the Shanghai Breast Cancer Study
    • DOI 10.1158/1055-9965.EPI-03-0273
    • MJ Shrubsole YT Gao Q Cai XO Shu Q Dai JR Hébert F Jin W Zheng 2004 MTHFR polymorphisms, dietary folate intake, and breast cancer risk: results from the shanghai breast cancer study Cancer Epidemiol Biomarkers Prev 13 2 190 196 1:CAS:528:DC%2BD2cXhtleisrg%3D 10.1158/1055-9965.EPI-03-0273 14973091 (Pubitemid 38222548)
    • (2004) Cancer Epidemiology Biomarkers and Prevention , vol.13 , Issue.2 , pp. 190-196
    • Shrubsole, M.J.1    Gao, Y.-T.2    Cai, Q.3    Shu, X.O.4    Dai, Q.5    Hebert, J.R.6    Jin, F.7    Zheng, W.8
  • 28
    • 34547778505 scopus 로고    scopus 로고
    • Polymorphisms of one-carbon-metabolizing genes and risk of breast cancer in a population-based study
    • DOI 10.1093/carcin/bgm061
    • X Xu MD Gammon H Zhang JG Wetmur M Rao SL Teitelbaum JA Britton AI Neugut RM Santella J Chen 2007 Polymorphisms of one-carbon-metabolizing genes and risk of breast cancer in a population-based study Carcinogenesis 28 7 1504 1509 1:CAS:528:DC%2BD2sXos12jurs%3D 10.1093/carcin/bgm061 17372271 (Pubitemid 47241800)
    • (2007) Carcinogenesis , vol.28 , Issue.7 , pp. 1504-1509
    • Xu, X.1    Gammon, M.D.2    Zhang, H.3    Wetmur, J.G.4    Rao, M.5    Teitelbaum, S.L.6    Britton, J.A.7    Neugut, A.I.8    Santella, R.M.9    Chen, J.10
  • 29
    • 47549118870 scopus 로고    scopus 로고
    • Polymorphism of cytosolic serine hydroxymethyltransferase, estrogen and breast cancer risk among Chinese women in Taiwan
    • DOI 10.1007/s10549-007-9754-x
    • CW Cheng JC Yu CS Huang JC Shieh YP Fu HW Wang PE Wu CY Shen 2008 Polymorphism of cytosolic serine hydroxymethyltransferase, estrogen and breast cancer risk among Chinese women in Taiwan Breast Cancer Res Treat 111 1 145 155 1:CAS:528:DC%2BD1cXos1Wnsbc%3D 10.1007/s10549-007-9754-x 17896178 (Pubitemid 352009223)
    • (2008) Breast Cancer Research and Treatment , vol.111 , Issue.1 , pp. 145-155
    • Cheng, C.-W.1    Yu, J.-C.2    Huang, C.-S.3    Shieh, J.-C.4    Fu, Y.-P.5    Wang, H.-W.6    Wu, P.-E.7    Shen, C.-Y.8
  • 31
    • 79952114981 scopus 로고    scopus 로고
    • Genetic polymorphisms in folate and alcohol metabolism and breast cancer risk: A case-control study in Thai women
    • 1:CAS:528:DC%2BC3cXhtFOqtL7E 10.1007/s10549-010-0804-4 20180013
    • S Sangrajrang Y Sato H Sakamoto S Ohnami T Khuhaprema T Yoshida 2010 Genetic polymorphisms in folate and alcohol metabolism and breast cancer risk: a case-control study in Thai women Breast Cancer Res Treat 123 3 885 893 1:CAS:528:DC%2BC3cXhtFOqtL7E 10.1007/s10549-010-0804-4 20180013
    • (2010) Breast Cancer Res Treat , vol.123 , Issue.3 , pp. 885-893
    • Sangrajrang, S.1    Sato, Y.2    Sakamoto, H.3    Ohnami, S.4    Khuhaprema, T.5    Yoshida, T.6
  • 34
    • 33645514418 scopus 로고    scopus 로고
    • MTR and MTRR polymorphisms, dietary intake, and breast cancer risk
    • 1:CAS:528:DC%2BD28Xit1OmsLY%3D 10.1158/1055-9965.EPI-05-0576 16537721
    • MJ Shrubsole Y Gao iQ Ca XO Shu Q Dai F Jin W Zheng 2006 MTR and MTRR polymorphisms, dietary intake, and breast cancer risk Cancer Epidemiol Biomarkers Prev 15 586 588 1:CAS:528:DC%2BD28Xit1OmsLY%3D 10.1158/1055-9965.EPI- 05-0576 16537721
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 586-588
    • Shrubsole, M.J.1    Gao, Y.2    Iq, C.3    Shu, X.O.4    Dai, Q.5    Jin, F.6    Zheng, W.7
  • 35
    • 33751355257 scopus 로고    scopus 로고
    • Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk
    • DOI 10.1093/jnci/djj440
    • SJ Lewis RM Harbord R Harris GD Smith 2006 Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk J Natl Cancer Inst 98 22 1607 1622 1:CAS:528:DC%2BD28XhtlSms7vN 10.1093/jnci/djj440 17105984 (Pubitemid 44811644)
    • (2006) Journal of the National Cancer Institute , vol.98 , Issue.22 , pp. 1607-1622
    • Lewis, S.J.1    Harbord, R.M.2    Harris, R.3    Smith, G.D.4
  • 36
    • 64349101889 scopus 로고    scopus 로고
    • One-carbon metabolism and breast cancer: An epidemiological perspective
    • 1:CAS:528:DC%2BD1MXlsFWkt7k%3D 10.1016/S1673-8527(08)60108-3 19376481
    • X Xu J Chen 2009 One-carbon metabolism and breast cancer: an epidemiological perspective J Genet Genomics 36 4 203 214 1:CAS:528: DC%2BD1MXlsFWkt7k%3D 10.1016/S1673-8527(08)60108-3 19376481
    • (2009) J Genet Genomics , vol.36 , Issue.4 , pp. 203-214
    • Xu, X.1    Chen, J.2
  • 37
    • 70249148054 scopus 로고    scopus 로고
    • Elevated level of 8-oxo-7,8-dihydro-2′-deoxyguanosine in leukocytes of BRCA1 mutation carriers compared to healthy controls
    • 1:CAS:528:DC%2BD1MXhtVOms7nP 10.1002/ijc.24600 19623658
    • T Dziaman T Huzarski D Gackowski R Rozalski A Siomek A Szpila J Guz J Lubinski R Olinski 2009 Elevated level of 8-oxo-7,8-dihydro-2′- deoxyguanosine in leukocytes of BRCA1 mutation carriers compared to healthy controls Int J Cancer 125 9 2209 2213 1:CAS:528:DC%2BD1MXhtVOms7nP 10.1002/ijc.24600 19623658
    • (2009) Int J Cancer , vol.125 , Issue.9 , pp. 2209-2213
    • Dziaman, T.1    Huzarski, T.2    Gackowski, D.3    Rozalski, R.4    Siomek, A.5    Szpila, A.6    Guz, J.7    Lubinski, J.8    Olinski, R.9
  • 38
    • 77949542434 scopus 로고    scopus 로고
    • 8-Hydroxydeoxyguanosine: A new potential independent prognostic factor in breast cancer
    • 1:CAS:528:DC%2BC3cXjt1ymsr8%3D 10.1038/sj.bjc.6605565 20179711
    • H Sova A Jukkola-Vuorinen U Puistola S Kauppila P Karihtala 2010 8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer Br J Cancer 102 6 1018 1023 1:CAS:528:DC%2BC3cXjt1ymsr8%3D 10.1038/sj.bjc.6605565 20179711
    • (2010) Br J Cancer , vol.102 , Issue.6 , pp. 1018-1023
    • Sova, H.1    Jukkola-Vuorinen, A.2    Puistola, U.3    Kauppila, S.4    Karihtala, P.5
  • 39
    • 0035874990 scopus 로고    scopus 로고
    • Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients
    • J Schmielau OJ Finn 2001 Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients Cancer Res 61 12 4756 4760 1:CAS:528: DC%2BD3MXks1Grtbg%3D 11406548 (Pubitemid 32691887)
    • (2001) Cancer Research , vol.61 , Issue.12 , pp. 4756-4760
    • Schmielau, J.1    Finn, O.J.2
  • 40
    • 0028015832 scopus 로고
    • Production of hydrogen peroxide by transforming growth factor-β1 and its involvement in induction of egr-1 in mouse osteoblastic cells
    • DOI 10.1083/jcb.126.4.1079
    • M Ohba M Shibanuma T Kuroki K Nose 1994 Production of hydrogen peroxide by transforming growth factor-beta 1 and its involvement in induction of egr-1 in mouse osteoblastic cells J Cell Biol 126 4 1079 1088 1:CAS:528: DyaK2cXlt1Kjsbo%3D 10.1083/jcb.126.4.1079 8051207 (Pubitemid 24252152)
    • (1994) Journal of Cell Biology , vol.126 , Issue.4 , pp. 1079-1088
    • Ohba, M.1    Shibanuma, M.2    Kuroki, T.3    Nose, K.4
  • 41
    • 0026021362 scopus 로고
    • Production of large amounts of hydrogen peroxide by human tumor cells
    • 1:CAS:528:DyaK3MXpvFagsw%3D%3D 1846317
    • TP Szatrowski CF Nathan 1991 Production of large amounts of hydrogen peroxide by human tumor cells Cancer Res 51 3 794 798 1:CAS:528: DyaK3MXpvFagsw%3D%3D 1846317
    • (1991) Cancer Res , vol.51 , Issue.3 , pp. 794-798
    • Szatrowski, T.P.1    Nathan, C.F.2
  • 42
    • 61449135006 scopus 로고    scopus 로고
    • Association of parental hyperhomocysteinemia and C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism with recurrent pregnancy loss
    • 1:CAS:528:DC%2BD1MXivVSjt7o%3D 10.1016/j.clinbiochem.2008.12.003 19111530
    • V Govindaiah SM Naushad K Prabhakara PC Krishna A Radha Rama Devi 2009 Association of parental hyperhomocysteinemia and C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism with recurrent pregnancy loss Clin Biochem 42 4-5 380 386 1:CAS:528:DC%2BD1MXivVSjt7o%3D 10.1016/j. clinbiochem.2008.12.003 19111530
    • (2009) Clin Biochem , vol.42 , Issue.45 , pp. 380-386
    • Govindaiah, V.1    Naushad, S.M.2    Prabhakara, K.3    Krishna, P.C.4    Radha Rama Devi, A.5
  • 43
    • 0034813210 scopus 로고    scopus 로고
    • Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-κB in human Hep G2 cells
    • DOI 10.1016/S0753-3322(01)00095-6
    • CL Chern RF Huang YH Chen JT Cheng TZ Liu 2001 Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells Biomed Pharmacother 55 8 434 442 1:CAS:528: DC%2BD3MXotlGktrg%3D 10.1016/S0753-3322(01)00095-6 11686576 (Pubitemid 32913567)
    • (2001) Biomedicine and Pharmacotherapy , vol.55 , Issue.8 , pp. 434-442
    • Chern, C.-L.1    Huang, R.-F.S.2    Chen, Y.-H.3    Cheng, J.-T.4    Liu, T.-Z.5
  • 44
    • 51049093216 scopus 로고    scopus 로고
    • The reduced folate carrier (RFC) is cytotoxic to cells underconditions of severe folate deprivation. RFC as a double edged sword in folate homeostasis
    • 1:CAS:528:DC%2BD1cXoslWrs7c%3D 10.1074/jbc.M802812200 18499665
    • I Ifergan G Jansen YG Assaraf 2008 The reduced folate carrier (RFC) is cytotoxic to cells underconditions of severe folate deprivation. RFC as a double edged sword in folate homeostasis J Biol Chem 283 30 20687 20695 1:CAS:528:DC%2BD1cXoslWrs7c%3D 10.1074/jbc.M802812200 18499665
    • (2008) J Biol Chem , vol.283 , Issue.30 , pp. 20687-20695
    • Ifergan, I.1    Jansen, G.2    Assaraf, Y.G.3
  • 45
    • 25144475606 scopus 로고    scopus 로고
    • Properties of human and rabbit cytosolic serine hydroxymethyltransferase are changed by single nucleotide polymorphic mutations
    • DOI 10.1016/j.abb.2005.07.018, PII S0003986105003127
    • TF Fu S Hunt V Schirch MK Safo BH Chen 2005 Properties of human and rabbit cytosolic serine hydroxymethyltransferase are changed by single nucleotide polymorphic mutations Arch Biochem Biophys 442 1 92 101 1:CAS:528:DC%2BD2MXhtVeiu7vM 10.1016/j.abb.2005.07.018 16137637 (Pubitemid 41334803)
    • (2005) Archives of Biochemistry and Biophysics , vol.442 , Issue.1 , pp. 92-101
    • Fu, T.-F.1    Hunt, S.2    Schirch, V.3    Safo, M.K.4    Chen, B.-H.5


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