-
1
-
-
0027958452
-
Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor
-
Samal B, Sun Y, Stearns G, Xie C, Suggs S, McNiece I. Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. Mol. Cell. Biol. 14(2), 1431-1437 (1994).
-
(1994)
Mol. Cell. Biol.
, vol.14
, Issue.2
, pp. 1431-1437
-
-
Samal, B.1
Sun, Y.2
Stearns, G.3
Xie, C.4
Suggs, S.5
McNiece, I.6
-
2
-
-
0035145516
-
Identification of a plasmid-encoded gene from Haemophilus ducreyi which confers NAD independence
-
Martin PR, Shea RJ, Mulks MH. Identification of a plasmid-encoded gene from Haemophilus ducreyi which confers NAD independence. J. Bacteriology 183(4), 1168-1174 (2001).
-
(2001)
J. Bacteriology
, vol.183
, Issue.4
, pp. 1168-1174
-
-
Martin, P.R.1
Shea, R.J.2
Mulks, M.H.3
-
3
-
-
0036856578
-
Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis
-
Rongvaux A, She RJ, Mulks MH et al. Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis. Eur. J. Immunol. 32(11), 3225-3234 (2002).
-
(2002)
Eur. J. Immunol.
, vol.32
, Issue.11
, pp. 3225-3234
-
-
Rongvaux, A.1
She, R.J.2
Mulks, M.H.3
-
4
-
-
19944433652
-
Visfatin: A protein secreted by visceral fat that Mimics the effects of insulin
-
Fukuhara A, Matsuda M, Nishizawa M et al. Visfatin: A protein secreted by visceral fat that Mimics the effects of insulin. Science 307(5708), 426-430 (2005).
-
(2005)
Science
, vol.307
, Issue.5708
, pp. 426-430
-
-
Fukuhara, A.1
Matsuda, M.2
Nishizawa, M.3
-
5
-
-
58049200121
-
Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism
-
Li Y, Zhang Y, Dorweiler B et al. Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism. J. Biol. Chem. 283(50), 34833-34843 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.50
, pp. 34833-34843
-
-
Li, Y.1
Zhang, Y.2
Dorweiler, B.3
-
6
-
-
33846527541
-
Visfatin, an adipocytokine with proinflammatory and immunomodulating properties
-
Moschen AR, Kaser A, Enrich B et al. Visfatin, an adipocytokine with proinflammatory and immunomodulating properties. J. Immunol. 178(3), 1748-1758 (2007).
-
(2007)
J. Immunol.
, vol.178
, Issue.3
, pp. 1748-1758
-
-
Moschen, A.R.1
Kaser, A.2
Enrich, B.3
-
7
-
-
63149089930
-
The NAD World: A new systemic regulatory network for metabolism and aging - Sirt1, systemic NAD biosyn
-
thesis, and their importance
-
Imai S. The NAD World: A new systemic regulatory network for metabolism and aging - Sirt1, systemic NAD biosynthesis, and their importance. Cell Biochem. Biophys. 53(2), 65-74 (2009).
-
(2009)
Cell Biochem. Biophys.
, vol.53
, Issue.2
, pp. 65-74
-
-
Imai, S.1
-
8
-
-
62649156291
-
Nampt: Linking nad biology, metabolism and cancer
-
Garten A, Petzold S, Korner A, Imai S, Kiess W. Nampt: Linking NAD biology, metabolism and cancer. Trends Endocrinol. Metab. 20(3), 130-138 (2009).
-
(2009)
Trends Endocrinol. Metab.
, vol.20
, Issue.3
, pp. 130-138
-
-
Garten, A.1
Petzold, S.2
Korner, A.3
Imai, S.4
Kiess, W.5
-
9
-
-
0023867160
-
The neurotrophic factor neuroleukin is 90% homologous with phosphohexose isomerase
-
Chaput M, Claes V, Portetelle D et al. The neurotrophic factor neuroleukin is 90% homologous with phosphohexose isomerase. Nature 332(6163), 454-455 (1988).
-
(1988)
Nature
, vol.332
, Issue.6163
, pp. 454-455
-
-
Chaput, M.1
Claes, V.2
Portetelle, D.3
-
10
-
-
0026647849
-
Leukocyte chemotactic activity of cyclophilin
-
Xu Q, Leiva MC, Fischkoff SA, Handschumacher RE, Lyttle CR. Leukocyte chemotactic activity of cyclophilin. J. Biol. Chem. 267(17), 11968-11971 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, Issue.17
, pp. 11968-11971
-
-
Xu, Q.1
Leiva, M.C.2
Fischkoff, S.A.3
Handschumacher, R.E.4
Lyttle, C.R.5
-
11
-
-
0028830210
-
CXC chemokines connective tissue activating peptide-III and neutrophil activating peptide-2 are heparin/heparan sulfate-degrading enzymes
-
Hoogewerf AJ, Leone JW, Reardon IM et al. CXC chemokines connective tissue activating peptide-III and neutrophil activating peptide-2 are heparin/heparan sulfate-degrading enzymes. J. Biol. Chem. 270(7), 3268-3277 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.7
, pp. 3268-3277
-
-
Hoogewerf, A.J.1
Leone, J.W.2
Reardon, I.M.3
-
12
-
-
0032127485
-
Direct link between cytokine activity and a catalytic site for macrophage migration inhibitory factor
-
Swope M, Sun HW, Blake PR, Lolis E. Direct link between cytokine activity and a catalytic site for macrophage migration inhibitory factor. EMBO J. 17(13), 3534-3541 (1998).
-
(1998)
EMBO J.
, vol.17
, Issue.13
, pp. 3534-3541
-
-
Swope, M.1
Sun, H.W.2
Blake, P.R.3
Lolis, E.4
-
13
-
-
50949120914
-
Nicotinic acid, nicotinamide, and nicotinamide riboside: A molecular evaluation of NAD+ precursor vitamins in human nutrition
-
Bogan KL, Brenner C. Nicotinic acid, nicotinamide, and nicotinamide riboside: A molecular evaluation of NAD+ precursor vitamins in human nutrition. Annu. Rev. Nutr. 28, 115-130 (2008).
-
(2008)
Annu. Rev. Nutr.
, vol.28
, pp. 115-130
-
-
Bogan, K.L.1
Brenner, C.2
-
15
-
-
0022503270
-
Characterization of an indoleamine 2,3-dioxygenase induced by gamma-interferon in cultured human fibroblasts
-
Pfefferkorn ER, Rebhun S, Eckel M. Characterization of an indoleamine 2,3-dioxygenase induced by gamma-interferon in cultured human fibroblasts. J. Interferon Res. 6(3), 267-279 (1986).
-
(1986)
J. Interferon Res.
, vol.6
, Issue.3
, pp. 267-279
-
-
Pfefferkorn, E.R.1
Rebhun, S.2
Eckel, M.3
-
16
-
-
33745894354
-
Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: Implications in the pathogenesis of rheumatoid arthritis
-
Nowell MA, Richards PJ, Fielding CA et al. Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: Implications in the pathogenesis of rheumatoid arthritis. Arthritis Rheum. 54(7), 2084-2095 (2006).
-
(2006)
Arthritis Rheum.
, vol.54
, Issue.7
, pp. 2084-2095
-
-
Nowell, M.A.1
Richards, P.J.2
Fielding, C.A.3
-
17
-
-
0036162677
-
Genes expressed during the IFNg induced maturation of pre-B cells
-
Patrone L, Damore MA, Lee MB, Malone CS, Wall R. Genes expressed during the IFNg induced maturation of pre-B cells. Mol. Immunol. 38(8), 597-606 (2002).
-
(2002)
Mol. Immunol.
, vol.38
, Issue.8
, pp. 597-606
-
-
Patrone, L.1
Damore, M.A.2
Lee, M.B.3
Malone, C.S.4
Wall, R.5
-
18
-
-
0035062540
-
Genomic organization of the gene coding for human pre-B-cell colony enhancing factor and expression in human fetal membranes
-
Ognjanovic S, Bao S, Yamamoto SY, Garibay-Tupas J, Samal B, Bryant-Greenwood GD. Genomic organization of the gene coding for human pre-B-cell colony enhancing factor and expression in human fetal membranes. J. Mol. Endocrinol. 26(2), 107-117 (2001).
-
(2001)
J. Mol. Endocrinol.
, vol.26
, Issue.2
, pp. 107-117
-
-
Ognjanovic, S.1
Bao, S.2
Yamamoto, S.Y.3
Garibay-Tupas, J.4
Samal, B.5
Bryant-Greenwood, G.D.6
-
19
-
-
0033959206
-
Fetal membrane distention I differentially expressed genes regulated by acute distention in amniotic epithelial (WISH) cells
-
Nemeth E, Tashima LS, Yu Z, Bryant-Greenwood GD. Fetal membrane distention: I. Differentially expressed genes regulated by acute distention in amniotic epithelial (WISH) cells. Am. J. Obstet. Gynecol. 182(1 Pt 1), 50-59 (2000).
-
(2000)
Am. J. Obstet. Gynecol.
, vol.182
, Issue.1 PART 1
, pp. 50-59
-
-
Nemeth, E.1
Tashima, L.S.2
Yu, Z.3
Bryant-Greenwood, G.D.4
-
20
-
-
33745826960
-
Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1
-
Bae SK, Kim SR, Kim JG et al. Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1. FEBS Lett. 580(17), 4105-4113 (2006).
-
(2006)
FEBS Lett.
, vol.580
, Issue.17
, pp. 4105-4113
-
-
Bae, S.K.1
Kim, S.R.2
Kim, J.G.3
-
21
-
-
65549118773
-
Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1
-
Nakahata Y, Sahar S, Astarita G, Kaluzova M, Sassone-Corsi P. Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. Science 324(5927), 654-657 (2009).
-
(2009)
Science
, vol.324
, Issue.5927
, pp. 654-657
-
-
Nakahata, Y.1
Sahar, S.2
Astarita, G.3
Kaluzova, M.4
Sassone-Corsi, P.5
-
22
-
-
34548627517
-
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
-
Yang H, Yang T, Baur JA et al. Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. Cell 130(6), 1095-1107 (2007).
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1095-1107
-
-
Yang, H.1
Yang, T.2
Baur, J.A.3
-
23
-
-
30044443515
-
Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity
-
Pillai JB, Isbatan A, Imai S, Gupta MP. Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity. J. Biol. Chem. 280(52), 43121-43130 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.52
, pp. 43121-43130
-
-
Pillai, J.B.1
Isbatan, A.2
Imai, S.3
Gupta, M.P.4
-
24
-
-
43049121395
-
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
-
Fulco M, Cen Y, Zhao P et al. Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev. Cell 14(5), 661-673 (2008).
-
(2008)
Dev. Cell
, vol.14
, Issue.5
, pp. 661-673
-
-
Fulco, M.1
Cen, Y.2
Zhao, P.3
-
25
-
-
22144459034
-
Pre-B-cell colony-enhancing factor regulates NAD+-dependent protein deacetylase activity and promotes vascular smooth muscle cell maturation
-
Van Der Veer E, Nong Z, O'Neil C, Urquhart B, Freeman D, Pickering JG. Pre-B-cell colony-enhancing factor regulates NAD+-dependent protein deacetylase activity and promotes vascular smooth muscle cell maturation. Circulation Res. 97(1), 25-34 (2005).
-
(2005)
Circulation Res.
, vol.97
, Issue.1
, pp. 25-34
-
-
Van Der Veer, E.1
Nong, Z.2
O'Neil, C.3
Urquhart, B.4
Freeman, D.5
Pickering, J.G.6
-
26
-
-
58149316660
-
Nicotinamide phosphoribosyl transferase/pre-B cell colony-enhancing factor/visfatin is required for lymphocyte development and cellular resistance to genotoxic stress
-
Rongvaux A, Galli M, Denanglaire S et al. Nicotinamide phosphoribosyl transferase/pre-B cell colony-enhancing factor/visfatin is required for lymphocyte development and cellular resistance to genotoxic stress. J. Immunol. 181(7), 4685-4695 (2008).
-
(2008)
J. Immunol.
, vol.181
, Issue.7
, pp. 4685-4695
-
-
Rongvaux, A.1
Galli, M.2
Denanglaire, S.3
-
27
-
-
10944270187
-
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
-
Revollo JR, Grimm AA, Imai S. The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. J. Biol. Chem. 279(49), 50754-50763 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.49
, pp. 50754-50763
-
-
Revollo, J.R.1
Grimm, A.A.2
Imai, S.3
-
28
-
-
0034142176
-
Rheumatoid arthritis and p53: How oxidative stress might alter the course of inflammatory diseases
-
Tak PP, Zvaifler NJ, Green DR, Firestein GS. Rheumatoid arthritis and p53: How oxidative stress might alter the course of inflammatory diseases. Immunol. Today 21(2), 78-82 (2000).
-
(2000)
Immunol. Today
, vol.21
, Issue.2
, pp. 78-82
-
-
Tak, P.P.1
Zvaifler, N.J.2
Green, D.R.3
Firestein, G.S.4
-
29
-
-
35648970517
-
Sirtuins, nuclear hormone receptor acetylation and transcriptional regulation
-
Whittle JR, Powell MJ, Popov VM, Shirley LA, Wang C, Pestell RG. Sirtuins, nuclear hormone receptor acetylation and transcriptional regulation. Trends Endocrinol. Metab. 18(9), 356-364 (2007).
-
(2007)
Trends Endocrinol. Metab.
, vol.18
, Issue.9
, pp. 356-364
-
-
Whittle, J.R.1
Powell, M.J.2
Popov, V.M.3
Shirley, L.A.4
Wang, C.5
Pestell, R.G.6
-
30
-
-
0036709074
-
Human Sir2 and the 'silencing' of p53 activity
-
Smith J. Human Sir2 and the 'silencing' of p53 activity. Trends Cell Biol. 12(9), 404-406 (2002).
-
(2002)
Trends Cell Biol.
, vol.12
, Issue.9
, pp. 404-406
-
-
Smith, J.1
-
31
-
-
80052453175
-
SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance
-
Niederer F, Ospelt C, Brentano F et al. SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann. Rheum. Dis. 70(10), 1866-1873 (2011).
-
(2011)
Ann. Rheum. Dis.
, vol.70
, Issue.10
, pp. 1866-1873
-
-
Niederer, F.1
Ospelt, C.2
Brentano, F.3
-
32
-
-
77951925741
-
Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue
-
Grabiec AM, Krausz S, de Jager W et al. Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue. J. Immunol. 184(5), 2718-2728 (2010).
-
(2010)
J. Immunol.
, vol.184
, Issue.5
, pp. 2718-2728
-
-
Grabiec, A.M.1
Krausz, S.2
De Jager, W.3
-
33
-
-
61349159991
-
Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase
-
Dvir-Ginzberg M, Gagarina V, Lee EJ, Hall DJ. Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase. J. Biol. Chem. 283(52), 36300-36310 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.52
, pp. 36300-36310
-
-
Dvir-Ginzberg, M.1
Gagarina, V.2
Lee, E.J.3
Hall, D.J.4
-
34
-
-
80051536994
-
Nicotinamide phosphoribosyltransferase is essential for interleukin-1beta-mediated dedifferentiation of articular chondrocytes via SIRT1 and extracellular signal-regulated kinase (ERK) complex signaling
-
Hong EH, Yun HS, Kim J et al. Nicotinamide phosphoribosyltransferase is essential for interleukin-1beta-mediated dedifferentiation of articular chondrocytes via SIRT1 and extracellular signal-regulated kinase (ERK) complex signaling. J. Biol. Chem. 286(32), 28619-28631 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, Issue.32
, pp. 28619-28631
-
-
Hong, E.H.1
Yun, H.S.2
Kim, J.3
-
35
-
-
59649117804
-
Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner
-
Van Gool F, Galli M, Gueydan C et al. Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner. Nat. Med. 15(2), 206-210 (2009).
-
(2009)
Nat. Med.
, vol.15
, Issue.2
, pp. 206-210
-
-
Van Gool, F.1
Galli, M.2
Gueydan, C.3
-
36
-
-
70949092805
-
Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE
-
Bruzzone S, Fruscione F, Morando S et al. Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE. PLoS One 4(11), e7897 (2009).
-
(2009)
Plos One
, vol.4
, Issue.11
-
-
Bruzzone, S.1
Fruscione, F.2
Morando, S.3
-
37
-
-
59649125761
-
NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway
-
Skokowa J, Lan D, Thakur BK et al. NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway. Nat. Med. 15(2), 151-158 (2009).
-
(2009)
Nat. Med.
, vol.15
, Issue.2
, pp. 151-158
-
-
Skokowa, J.1
Lan, D.2
Thakur, B.K.3
-
38
-
-
35549002189
-
Nampt/PBEF/visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme
-
Revollo JR, Korner A, Mills KF et al. Nampt/PBEF/visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. Cell Metab. 6(5), 363-375 (2007).
-
(2007)
Cell Metab.
, vol.6
, Issue.5
, pp. 363-375
-
-
Revollo, J.R.1
Korner, A.2
Mills, K.F.3
-
39
-
-
79954634068
-
Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre-B cell colony (PBEF)/visfatin linking obesity and inflammation in humans
-
Friebe D, Neef M, Kratzsch J et al. Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre-B cell colony (PBEF)/visfatin linking obesity and inflammation in humans. Diabetologia 54(5), 1200-1211 (2011).
-
(2011)
Diabetologia
, vol.54
, Issue.5
, pp. 1200-1211
-
-
Friebe, D.1
Neef, M.2
Kratzsch, J.3
-
40
-
-
34848847894
-
Pre-B cell colony-enhancing factor/visfatin, a new marker of inflammation in rheumatoid arthritis with proinflammatory and matrix-degrading activities
-
Brentano F, Schorr O, Ospelt C et al. Pre-B cell colony-enhancing factor/visfatin, a new marker of inflammation in rheumatoid arthritis with proinflammatory and matrix-degrading activities. Arth. Rheum. 56(9), 2829-2839 (2007).
-
(2007)
Arth. Rheum.
, vol.56
, Issue.9
, pp. 2829-2839
-
-
Brentano, F.1
Schorr, O.2
Ospelt, C.3
-
41
-
-
25844491778
-
Plasma visfatin concentrations and fat depot-specific mRNA expression in humans
-
Berndt J, KlÖting N, Kralisch S et al. Plasma visfatin concentrations and fat depot-specific mRNA expression in humans. Diabetes 54(10), 2911-2916 (2005).
-
(2005)
Diabetes
, vol.54
, Issue.10
, pp. 2911-2916
-
-
Berndt, J.1
KlÖting, N.2
Kralisch, S.3
-
42
-
-
33846693322
-
The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals
-
Revollo JR, Grimm AA, Imai SI. The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals. Curr. Opin. Gastroenterol. 23(2), 164-170 (2007).
-
(2007)
Curr. Opin. Gastroenterol.
, vol.23
, Issue.2
, pp. 164-170
-
-
Revollo, J.R.1
Grimm, A.A.2
Imai, S.I.3
-
43
-
-
33644826101
-
Macrophages in human visceral adipose tissue: Increased accumulation in obesity and a source of resistin and visfatin
-
Curat CA, Wegner V, Sengenes C et al. Macrophages in human visceral adipose tissue: Increased accumulation in obesity and a source of resistin and visfatin. Diabetologia 49(4), 744-747 (2006).
-
(2006)
Diabetologia
, vol.49
, Issue.4
, pp. 744-747
-
-
Curat, C.A.1
Wegner, V.2
Sengenes, C.3
-
44
-
-
85047693796
-
Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis
-
Jia SH, Li Y, Parodo J et al. Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. J. Clin. Invest. 113(9), 1318-1327 (2004).
-
(2004)
J. Clin. Invest.
, vol.113
, Issue.9
, pp. 1318-1327
-
-
Jia, S.H.1
Li, Y.2
Parodo, J.3
-
45
-
-
37849187450
-
Visfatin is present in bovine mammary epithelial cells, lactating mammary gland and milk, and its expression is regulated by cAMP pathway
-
Yonezawa T, Haga S, Kobayashi Y, Takahashi T, Obara Y. Visfatin is present in bovine mammary epithelial cells, lactating mammary gland and milk, and its expression is regulated by cAMP pathway. FEBS Lett. 580(28-29), 6635-6643 (2006).
-
(2006)
FEBS Lett.
, vol.580
, Issue.28-29
, pp. 6635-6643
-
-
Yonezawa, T.1
Haga, S.2
Kobayashi, Y.3
Takahashi, T.4
Obara, Y.5
-
46
-
-
72949097428
-
Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes
-
Garten A, Petzold S, Barnikol-Oettler A et al. Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes. Biochem. Biophys. Res. Commun. 391(1), 376-381 (2009).
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.391
, Issue.1
, pp. 376-381
-
-
Garten, A.1
Petzold, S.2
Barnikol-Oettler, A.3
-
47
-
-
34249950921
-
Visfatin is released from 3T3-L1 adipocytes via a non-classical pathway
-
Tanaka M, Nozaki M, Fukuhara A et al. Visfatin is released from 3T3-L1 adipocytes via a non-classical pathway. Biochem. Biophys. Res. Commun. 359(2), 194-201 (2007).
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.359
, Issue.2
, pp. 194-201
-
-
Tanaka, M.1
Nozaki, M.2
Fukuhara, A.3
-
48
-
-
39649100626
-
Serum visfatin concentrations in obese adolescents and its correlation with age and high-density lipoprotein cholesterol
-
Jin H, Jiang B, Tang J et al. Serum visfatin concentrations in obese adolescents and its correlation with age and high-density lipoprotein cholesterol. Diabetes Res. Clin. Pract. 79(3), 412-418 (2008).
-
(2008)
Diabetes Res. Clin. Pract.
, vol.79
, Issue.3
, pp. 412-418
-
-
Jin, H.1
Jiang, B.2
Tang, J.3
-
49
-
-
79960739831
-
A key role for pre-B-cell colony-enhancing factor in experimental hepatitis
-
Moschen AR, Gerner R, Schroll A, Fritz T, Kaser A, Tilg H. A key role for pre-B-cell colony-enhancing factor in experimental hepatitis. Hepatology 54(2), 675-686 (2011).
-
(2011)
Hepatology
, vol.54
, Issue.2
, pp. 675-686
-
-
Moschen, A.R.1
Gerner, R.2
Schroll, A.3
Fritz, T.4
Kaser, A.5
Tilg, H.6
-
50
-
-
67650644583
-
Adipocytokines in systemic lupus erythematosus: Relationship to inflammation, insulin resistance and coronary atherosclerosis
-
Chung CP, Long AG, Solus JF et al. Adipocytokines in systemic lupus erythematosus: Relationship to inflammation, insulin resistance and coronary atherosclerosis. Lupus 18(9), 799-806 (2009).
-
(2009)
Lupus
, vol.18
, Issue.9
, pp. 799-806
-
-
Chung, C.P.1
Long, A.G.2
Solus, J.F.3
-
51
-
-
13544251479
-
Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury
-
Ye SQ, Simon BA, Maloney JP et al. Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. Am. J. Respir. Crit. Care Med. 171(4), 361-370 (2005).
-
(2005)
Am. J. Respir. Crit. Care Med.
, vol.171
, Issue.4
, pp. 361-370
-
-
Ye, S.Q.1
Simon, B.A.2
Maloney, J.P.3
-
52
-
-
33846630857
-
Circulating levels of visfatin/pre-B-cell colony-enhancing factor 1 in relation to genotype, GFR, body composition, and survival in patients with CKD
-
Axelsson J, Witasp A, Carrero JJ et al. Circulating levels of visfatin/pre-B-cell colony-enhancing factor 1 in relation to genotype, GFR, body composition, and survival in patients with CKD. Am. J. Kidney Dis. 49(2), 237-244 (2007).
-
(2007)
Am. J. Kidney Dis.
, vol.49
, Issue.2
, pp. 237-244
-
-
Axelsson, J.1
Witasp, A.2
Carrero, J.J.3
-
53
-
-
33747786726
-
Changes in plasma levels of fat-derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis
-
Otero M, Lago R, Gomez R et al. Changes in plasma levels of fat-derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis. Ann. Rheumatic Dis. 65(9), 1198-1201 (2006).
-
(2006)
Ann. Rheumatic Dis.
, vol.65
, Issue.9
, pp. 1198-1201
-
-
Otero, M.1
Lago, R.2
Gomez, R.3
-
54
-
-
61349104750
-
Peritoneal fluid adipokines: Ready for prime time? Eur
-
Wiest R, Leidl F, Kopp A et al. Peritoneal fluid adipokines: Ready for prime time? Eur. J. Clin. Invest. 39(3), 219-229 (2009).
-
(2009)
J. Clin. Invest.
, vol.39
, Issue.3
, pp. 219-229
-
-
Wiest, R.1
Leidl, F.2
Kopp, A.3
-
55
-
-
55749103395
-
Visfatin/pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: An association with subclinical intrauterine infection in preterm parturition
-
Mazaki-Tovi S, Romero R, Kusanovic JP et al. Visfatin/pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: An association with subclinical intrauterine infection in preterm parturition. J. Perinat. Med. 36(6), 485-496 (2008).
-
(2008)
J. Perinat. Med.
, vol.36
, Issue.6
, pp. 485-496
-
-
Mazaki-Tovi, S.1
Romero, R.2
Kusanovic, J.P.3
-
56
-
-
62749111474
-
Relationship between cerebrospinal fluid visfatin (PBEF/Nampt) levels and adiposity in humans
-
Hallschmid M, Randeva H, Tan BK, Kern W, Lehnert H. Relationship between cerebrospinal fluid visfatin (PBEF/Nampt) levels and adiposity in humans. Diabetes 58(3), 637-640 (2009).
-
(2009)
Diabetes
, vol.58
, Issue.3
, pp. 637-640
-
-
Hallschmid, M.1
Randeva, H.2
Tan, B.K.3
Kern, W.4
Lehnert, H.5
-
57
-
-
67650066805
-
Adipocytokines are associated with radiographic joint damage in rheumatoid arthritis
-
Rho YH, Solus J, Sokka T et al. Adipocytokines are associated with radiographic joint damage in rheumatoid arthritis. Arthritis Rheum. 60(7), 1906-1914 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, Issue.7
, pp. 1906-1914
-
-
Rho, Y.H.1
Solus, J.2
Sokka, T.3
-
58
-
-
79956360551
-
The level of serum visfatin (PBEF) is associated with total number of B cells in patients with rheumatoid arthritis and decreases following B cell depletion therapy
-
Senolt L, Krystufkova O, Hulejova H et al. The level of serum visfatin (PBEF) is associated with total number of B cells in patients with rheumatoid arthritis and decreases following B cell depletion therapy. Cytokine 55(1), 116-121 (2011).
-
(2011)
Cytokine
, vol.55
, Issue.1
, pp. 116-121
-
-
Senolt, L.1
Krystufkova, O.2
Hulejova, H.3
-
59
-
-
77949508778
-
Visfatin is not associated with inflammation or metabolic syndrome in patients with severe rheumatoid arthritis undergoing anti-TNF-Alpha therapy
-
Gonzalez-Gay MA, Vazquez-Rodriguez TR, Garcia-Unzueta MT et al. Visfatin is not associated with inflammation or metabolic syndrome in patients with severe rheumatoid arthritis undergoing anti-TNF-Alpha therapy. Clin. Exp. Rheumatol. 28(1), 56-62 (2010).
-
(2010)
Clin. Exp. Rheumatol.
, vol.28
, Issue.1
, pp. 56-62
-
-
Gonzalez-Gay, M.A.1
Vazquez-Rodriguez, T.R.2
Garcia-Unzueta, M.T.3
-
60
-
-
41849119173
-
Visfatin (pre-B cell colony-enhancing factor) gene expression in patients with rheumatoid arthritis
-
Matsui H, Tsutsumi A, Sugihara M et al. Visfatin (pre-B cell colony-enhancing factor) gene expression in patients with rheumatoid arthritis. Ann. Rheumatic Dis. 67(4), 571-572 (2008).
-
(2008)
Ann. Rheumatic Dis.
, vol.67
, Issue.4
, pp. 571-572
-
-
Matsui, H.1
Tsutsumi, A.2
Sugihara, M.3
-
61
-
-
77951803595
-
Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets
-
Mesko B, Poliska S, Szegedi A et al. Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets. BMC Med. Genomics 3, 15 (2010).
-
(2010)
BMC Med. Genomics
, vol.3
, pp. 15
-
-
Mesko, B.1
Poliska, S.2
Szegedi, A.3
-
62
-
-
33644913982
-
TNF regulates cellular NAD+ metabolism in primary macrophages
-
Iqbal J, Zaidi M. TNF regulates cellular NAD+ metabolism in primary macrophages. Biochem. Biophys. Res. Comm. 342(4), 1312-1318 (2006).
-
(2006)
Biochem. Biophys. Res. Comm.
, vol.342
, Issue.4
, pp. 1312-1318
-
-
Iqbal, J.1
Zaidi, M.2
-
63
-
-
84860249920
-
Inhibition of nicotinamide phosphoribosyltransferase modifies LPS-induced inflammatory responses of human monocytes
-
doi:10.1177/1753425911428553 Epub ahead of print
-
Schilling E, Wehrhahn J, Klein C, Raulien N, Ceglarek U, Hauschildt S. Inhibition of nicotinamide phosphoribosyltransferase modifies LPS-induced inflammatory responses of human monocytes. Innate Immun. doi:10.1177/ 1753425911428553 (2011) (Epub ahead of print).
-
(2011)
Innate Immun.
-
-
Schilling, E.1
Wehrhahn, J.2
Klein, C.3
Raulien, N.4
Ceglarek, U.5
Hauschildt, S.6
-
64
-
-
33847279330
-
Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: Possible role in inflammation and plaque destabilization
-
Dahl TB, Yndestad A, Skjelland M et al. Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: Possible role in inflammation and plaque destabilization. Circulation 115(8), 972-980 (2007).
-
(2007)
Circulation
, vol.115
, Issue.8
, pp. 972-980
-
-
Dahl, T.B.1
Yndestad, A.2
Skjelland, M.3
-
65
-
-
30344471828
-
Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus
-
Chen MP, Chung FM, Chang DM et al. Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. J. Clin. Endocrinol. Metab. 91(1), 295-299 (2006).
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, Issue.1
, pp. 295-299
-
-
Chen, M.P.1
Chung, F.M.2
Chang, D.M.3
-
66
-
-
79954878322
-
Expression patterns of nicotinamide phosphoribosyltransferase and nicotinic acid phosphoribosyltransferase in human malignant lymphomas
-
Olesen UH, Hastrup N, Sehested M. Expression patterns of nicotinamide phosphoribosyltransferase and nicotinic acid phosphoribosyltransferase in human malignant lymphomas. APMIS 119(4-5), 296-303 (2011).
-
(2011)
APMIS
, vol.119
, Issue.4-5
, pp. 296-303
-
-
Olesen, U.H.1
Hastrup, N.2
Sehested, M.3
-
67
-
-
77956037515
-
Over-expression of nicotinamide phosphoribosyltransferase in ovarian cancers
-
Shackelford RE, Bui MM, Coppola D, Hakam A. Over-expression of nicotinamide phosphoribosyltransferase in ovarian cancers. Int. J. Clin. Exp. Pathol. 3(5), 522-527 (2010).
-
(2010)
Int. J. Clin. Exp. Pathol.
, vol.3
, Issue.5
, pp. 522-527
-
-
Shackelford, R.E.1
Bui, M.M.2
Coppola, D.3
Hakam, A.4
-
68
-
-
0033461164
-
A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization
-
Hufton SE, Moerkerk PT, Brandwijk R, De Bruïne AP, Arends JW, Hoogenboom HR. A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization. FEBS Lett. 463(1-2), 77-82 (1999).
-
(1999)
FEBS Lett.
, vol.463
, Issue.1-2
, pp. 77-82
-
-
Hufton, S.E.1
Moerkerk, P.T.2
Brandwijk, R.3
De Bruïne, A.P.4
Arends, J.W.5
Hoogenboom, H.R.6
-
69
-
-
33845476276
-
Increased visfatin messenger ribonucleic acid and protein levels in adipose tissue and adipocytes in women with polycystic ovary syndrome: Parallel increase in plasma visfatin
-
Tan BK, Chen J, Digby JE, Keay SD, Kennedy CR, Randeva HS. Increased visfatin messenger ribonucleic acid and protein levels in adipose tissue and adipocytes in women with polycystic ovary syndrome: Parallel increase in plasma visfatin. J. Clin. Endocrinol. Metab. 91(12), 5022-5028 (2006).
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, Issue.12
, pp. 5022-5028
-
-
Tan, B.K.1
Chen, J.2
Digby, J.E.3
Keay, S.D.4
Kennedy, C.R.5
Randeva, H.S.6
-
70
-
-
0036795752
-
Pre-B-cell colony-enhancing factor, a novel cytokine of human fetal membranes
-
Ognjanovic S, Bryant-Greenwood GD. Pre-B-cell colony-enhancing factor, a novel cytokine of human fetal membranes. Am. J. Obstet. Gynecol. 187(4), 1051-1058 (2002).
-
(2002)
Am. J. Obstet. Gynecol.
, vol.187
, Issue.4
, pp. 1051-1058
-
-
Ognjanovic, S.1
Bryant-Greenwood, G.D.2
-
71
-
-
79959611231
-
Visfatin levels and intima-media thicknesses in rheumatic diseases
-
Ozgen M, Koca SS, Aksoy K, Dagli N, Ustundag B, Isik A. Visfatin levels and intima-media thicknesses in rheumatic diseases. Clin. Rheumatol. 30(6), 757-763 (2010).
-
(2010)
Clin. Rheumatol.
, vol.30
, Issue.6
, pp. 757-763
-
-
Ozgen, M.1
Koca, S.S.2
Aksoy, K.3
Dagli, N.4
Ustundag, B.5
Isik, A.6
-
72
-
-
64849109200
-
Adipokines and systemic lupus erythematosus: Relationship with metabolic syndrome and cardiovascular disease risk factors
-
Vadacca M, Margiotta D, Rigon A et al. Adipokines and systemic lupus erythematosus: Relationship with metabolic syndrome and cardiovascular disease risk factors. J. Rheumatol. 36(2), 295-297 (2009).
-
(2009)
J. Rheumatol.
, vol.36
, Issue.2
, pp. 295-297
-
-
Vadacca, M.1
Margiotta, D.2
Rigon, A.3
-
73
-
-
84860254643
-
Pre-B Cell Colony-enhancing factor as a marker of erosions in rheumatoid arthritis patients
-
Zifzaf D, Kaddah E, El Bakri S, ElZaher A, Abo-Shady R. Pre-B Cell Colony-enhancing factor as a marker of erosions in rheumatoid arthritis patients. Life Sci. J. 8(4), 628-634 (2011).
-
(2011)
Life Sci. J.
, vol.8
, Issue.4
, pp. 628-634
-
-
Zifzaf, D.1
Kaddah, E.2
El Bakri, S.3
ElZaher, A.4
Abo-Shady, R.5
-
74
-
-
79959823404
-
Suppression of leukocyte infiltration and cartilage degradation by selective inhibition of pre-B cell colony-enhancing factor/visfatin/nicotinamide phosphoribosyltransferase: Apo866-mediated therapy in human fibroblasts and murine collagen-induced arthritis
-
Evans L, Williams AS, Hayes AJ, Jones SA, Nowell M. Suppression of leukocyte infiltration and cartilage degradation by selective inhibition of pre-B cell colony-enhancing factor/visfatin/nicotinamide phosphoribosyltransferase: Apo866-mediated therapy in human fibroblasts and murine collagen-induced arthritis. Arthritis Rheum. 63(7), 1866-1877 (2011).
-
(2011)
Arthritis Rheum.
, vol.63
, Issue.7
, pp. 1866-1877
-
-
Evans, L.1
Williams, A.S.2
Hayes, A.J.3
Jones, S.A.4
Nowell, M.5
-
75
-
-
43949131087
-
Crucial role of visfatin/pre-B cell colony-enhancing factor in matrix degradation and prostaglandin E2 synthesis in chondrocytes: Possible influence on osteoarthritis
-
Gosset M, Berenbaum F, Salvat C et al. Crucial role of visfatin/pre-B cell colony-enhancing factor in matrix degradation and prostaglandin E2 synthesis in chondrocytes: Possible influence on osteoarthritis. Arthritis Rheum. 58(5), 1399-1409 (2008).
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.5
, pp. 1399-1409
-
-
Gosset, M.1
Berenbaum, F.2
Salvat, C.3
-
76
-
-
84856291934
-
Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes
-
Yammani RR, Loeser RF Jr. Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes. Arthritis Res. Ther. 14(1), R23 (2011).
-
(2011)
Arthritis Res. Ther.
, vol.14
, Issue.1
-
-
Yammani, R.R.1
Loeser Jr., R.F.2
-
77
-
-
80054979571
-
Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: A possible cause for reduced osteogenesis and increased adipogenesis in older individuals
-
Li Y, He X, He J, Anderstam B, Andersson G, Lindgren U. Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: A possible cause for reduced osteogenesis and increased adipogenesis in older individuals. J. Bone Miner. Res. 26(11), 2656-2664 (2011).
-
(2011)
J. Bone Miner. Res.
, vol.26
, Issue.11
, pp. 2656-2664
-
-
Li, Y.1
He, X.2
He, J.3
Anderstam, B.4
Andersson, G.5
Lindgren, U.6
-
78
-
-
82355190885
-
Sirt1 is a regulator of bone mass and a repressor of Sost encoding for sclerostin, a bone formation inhibitor
-
Cohen-Kfir E, Artsi H, Levin A et al. Sirt1 is a regulator of bone mass and a repressor of Sost encoding for sclerostin, a bone formation inhibitor. Endocrinology 152(12), 4514-4524 (2011).
-
(2011)
Endocrinology
, vol.152
, Issue.12
, pp. 4514-4524
-
-
Cohen-Kfir, E.1
Artsi, H.2
Levin, A.3
-
79
-
-
0034802541
-
Signatures of the immune response
-
Shaffer AL, Rosenwald A, Hurt EM et al. Signatures of the immune response. Immunity 15(3), 375-385 (2001).
-
(2001)
Immunity
, vol.15
, Issue.3
, pp. 375-385
-
-
Shaffer, A.L.1
Rosenwald, A.2
Hurt, E.M.3
-
80
-
-
79958071347
-
Pre-B cell colony-enhancing factor (PBEF/Nampt/visfatin) primes neutrophils for augmented respiratory burst activity through partial assembly of the NADPH oxidase
-
Malam Z, Parodo J, Waheed F, Szaszi K, Kapus A, Marshall JC. Pre-B cell colony-enhancing factor (PBEF/Nampt/visfatin) primes neutrophils for augmented respiratory burst activity through partial assembly of the NADPH oxidase. J. Immunol. 186(11), 6474-6484 (2011).
-
(2011)
J. Immunol.
, vol.186
, Issue.11
, pp. 6474-6484
-
-
Malam, Z.1
Parodo, J.2
Waheed, F.3
Szaszi, K.4
Kapus, A.5
Marshall, J.C.6
-
81
-
-
77955282709
-
Pre-B cell colony enhancing factor/NAMPT/visfatin and its role in inflammation-related bone disease
-
Moschen AR, Geiger S, Gerner R, Tilg H. Pre-B cell colony enhancing factor/NAMPT/visfatin and its role in inflammation-related bone disease. Mutat Res, 690(1-2), 95-101 (2010).
-
(2010)
Mutat. Res.
, vol.690
, Issue.1-2
, pp. 95-101
-
-
Moschen, A.R.1
Geiger, S.2
Gerner, R.3
Tilg, H.4
-
82
-
-
84860258091
-
Decreased Expression of nicotinamide phosphoribosyltransferase (NAMPT) in active juvenile idiopathic arthritis patients receiving methotrexate
-
Chicago IL, USA 4-9 November
-
Fox EJ, Gibson M, Zhang LQ, Leeder JS, Ye SQ, Becker ML. Decreased Expression of nicotinamide phosphoribosyltransferase (NAMPT) in active juvenile idiopathic arthritis patients receiving methotrexate. Presented at: American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting. Chicago, IL, USA 4-9 November 2011.
-
(2011)
Presented at: American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting
-
-
Fox, E.J.1
Gibson, M.2
Zhang, L.Q.3
Leeder, J.S.4
Ye, S.Q.5
Becker, M.L.6
-
83
-
-
84860249918
-
Anti-TNF therapy reduces adipocytokine levels and improves the lipid profile in patients with rheumatoid arthritis: A possible mechanism contributing to lowered cardiovascular risk
-
Atlanta, GA, USA 6-11 November
-
Herenius M, Klaasen R, de Jager W, Prakken BJ, Gerlag D, Tak PP. Anti-TNF therapy reduces adipocytokine levels and improves the lipid profile in patients with rheumatoid arthritis: A possible mechanism contributing to lowered cardiovascular risk. Presented at: American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting. Atlanta, GA, USA 6-11 November 2010.
-
(2010)
Presented at: American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting
-
-
Herenius, M.1
Klaasen, R.2
De Jager, W.3
Prakken, B.J.4
Gerlag, D.5
Tak, P.P.6
-
84
-
-
0345643131
-
Treatment of arthritis by nicotinic acid and nicotinamide
-
Hoffer A. Treatment of arthritis by nicotinic acid and nicotinamide. Can. Med. Assoc. J. 81, 235-238 (1959).
-
(1959)
Can. Med. Assoc. J.
, vol.81
, pp. 235-238
-
-
Hoffer, A.1
-
85
-
-
0026490408
-
Pharmacokinetics of nicotinamide and its effect on blood pressure, pulse and body temperature in normal human volunteers
-
Stratford MR, Rojas A, Hall DW et al. Pharmacokinetics of nicotinamide and its effect on blood pressure, pulse and body temperature in normal human volunteers. Radiother. Oncol. 25(1), 37-42 (1992).
-
(1992)
Radiother. Oncol.
, vol.25
, Issue.1
, pp. 37-42
-
-
Stratford, M.R.1
Rojas, A.2
Hall, D.W.3
-
86
-
-
0036170579
-
WK175, a novel anti-Tumor agent, decreases the intracellular nicotinamide adenine dinucleotide concentration and induces the apoptotic cascade in human leukemia cells
-
Wosikowski K, Mattern K, Schemainda I, Hasmann M, Rattel B, Loser R. WK175, a novel anti-Tumor agent, decreases the intracellular nicotinamide adenine dinucleotide concentration and induces the apoptotic cascade in human leukemia cells. Cancer Res. 62(4), 1057-1062 (2002).
-
(2002)
Cancer Res.
, vol.62
, Issue.4
, pp. 1057-1062
-
-
Wosikowski, K.1
Mattern, K.2
Schemainda, I.3
Hasmann, M.4
Rattel, B.5
Loser, R.6
-
87
-
-
0242526050
-
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis
-
Hasmann M, Schemainda I. FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Res. 63(21), 7436-7442 (2003).
-
(2003)
Cancer Res.
, vol.63
, Issue.21
, pp. 7436-7442
-
-
Hasmann, M.1
Schemainda, I.2
-
88
-
-
0842333189
-
Antiangiogenic potency of FK866/K22.175 a new inhibitor of intracellular NAD biosyn thesis in murine renal cell carcinoma
-
Drevs J, Loser R, Rattel B, Esser N. Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma. Anticancer Res. 23(6C), 4853-4858 (2003).
-
(2003)
Anticancer Res.
, vol.23
, Issue.6 C
, pp. 4853-4858
-
-
Drevs, J.1
Loser, R.2
Rattel, B.3
Esser, N.4
-
89
-
-
18244376911
-
Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy
-
Muruganandham M, Alfieri AA, Matei C et al. Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy. Clin. Cancer Res. 11(9), 3503-3513 (2005).
-
(2005)
Clin. Cancer Res.
, vol.11
, Issue.9
, pp. 3503-3513
-
-
Muruganandham, M.1
Alfieri, A.A.2
Matei, C.3
-
90
-
-
38149105811
-
The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor
-
Holen K, Saltz L, Hollywood E, Burk K, Hanauske A. The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor. Invest. New Drugs 26(1), 45-51 (2008).
-
(2008)
Invest. New Drugs
, vol.26
, Issue.1
, pp. 45-51
-
-
Holen, K.1
Saltz, L.2
Hollywood, E.3
Burk, K.4
Hanauske, A.5
-
91
-
-
79959823404
-
Selective inhibition of PBEF/Visfatin/NAMPT supresses leukocyte infiltration and cartilage degradation
-
Evans LE, Williams AS, Hayes AJ, Jones SA, Nowell MA. Selective inhibition of PBEF/Visfatin/NAMPT supresses leukocyte infiltration and cartilage degradation. Arthritis Rheum. 63(7), 1866-1877 (2011).
-
(2011)
Arthritis Rheum.
, vol.63
, Issue.7
, pp. 1866-1877
-
-
Evans, L.E.1
Williams, A.S.2
Hayes, A.J.3
Jones, S.A.4
Nowell, M.A.5
-
92
-
-
48249105497
-
Pharmacological inhibition of nicotinamide phosphoribosyltransferase/ visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD
-
Busso N, Karababa M, Nobile M et al. Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD. PLoS One 3(5), e2267 (2008).
-
(2008)
Plos One
, vol.3
, Issue.5
-
-
Busso, N.1
Karababa, M.2
Nobile, M.3
-
93
-
-
33745817828
-
Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents
-
Khan JA, Tao X, Tong L. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat. Struct. Mol. Biol. 13(7), 582-588 (2006).
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, Issue.7
, pp. 582-588
-
-
Khan, J.A.1
Tao, X.2
Tong, L.3
-
94
-
-
33747624726
-
Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866
-
Kim MK, Lee JH, Kim H et al. Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866. J. Mol. Biol. 362(1), 66-77 (2006).
-
(2006)
J. Mol. Biol.
, vol.362
, Issue.1
, pp. 66-77
-
-
Kim, M.K.1
Lee, J.H.2
Kim, H.3
-
95
-
-
24344464365
-
The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases
-
Chappie JS, Canaves JM, Han GW, Rife CL, Xu Q, Stevens RC. The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases. Structure 13(9), 1385-1396 (2005).
-
(2005)
Structure
, vol.13
, Issue.9
, pp. 1385-1396
-
-
Chappie, J.S.1
Canaves, J.M.2
Han, G.W.3
Rife, C.L.4
Xu, Q.5
Stevens, R.C.6
-
96
-
-
78049325660
-
In vivo molecular imaging of experimental joint inflammation by combined 18)F-FDG positron emission tomography and computed tomography
-
Irmler IM, Opfermann T, Gebhardt P et al. In vivo molecular imaging of experimental joint inflammation by combined (18)F-FDG positron emission tomography and computed tomography. Arthritis Res. Ther. 12(6), R203 (2010).
-
(2010)
Arthritis Res. Ther.
, vol.12
, Issue.6
-
-
Irmler, I.M.1
Opfermann, T.2
Gebhardt, P.3
-
97
-
-
0036716986
-
A Phase I study of CHS 828 in patients with solid tumor malignancy
-
Hovstadius P, Larsson R, Jonsson E et al. A Phase I study of CHS 828 in patients with solid tumor malignancy. Clin. Cancer Res. 8(9), 2843-2850 (2002).
-
(2002)
Clin. Cancer Res.
, vol.8
, Issue.9
, pp. 2843-2850
-
-
Hovstadius, P.1
Larsson, R.2
Jonsson, E.3
-
98
-
-
14844291424
-
Phase I study and pharmacokinetic of CHS-828, a guanidino-containing compound, administered orally as a single dose every 3 weeks in solid tumours: An ECSG/EORTC study
-
Ravaud A, Cerny T, Terret C et al. Phase I study and pharmacokinetic of CHS-828, a guanidino-containing compound, administered orally as a single dose every 3 weeks in solid tumours: An ECSG/EORTC study. Eur. J. Cancer 41(5), 702-707 (2005).
-
(2005)
Eur. J. Cancer
, vol.41
, Issue.5
, pp. 702-707
-
-
Ravaud, A.1
Cerny, T.2
Terret, C.3
-
99
-
-
77951887249
-
Safety and efficacy of NAD depleting cancer drugs: Results of a Phase I clinical trial of CHS 828 and overview of published data
-
von Heideman A, Berglund Ö, Larsson R, Nygren P. Safety and efficacy of NAD depleting cancer drugs: Results of a Phase I clinical trial of CHS 828 and overview of published data. Cancer Chemother. Pharmacol. 65(6), 1165-1172 (2010).
-
(2010)
Cancer Chemother. Pharmacol.
, vol.65
, Issue.6
, pp. 1165-1172
-
-
Von Heideman, A.1
Berglund, Ö.2
Larsson, R.3
Nygren, P.4
-
100
-
-
77953408297
-
A preclinical study on the rescue of normal tissue by nicotinic acid in high-dose treatment with APO866, a specific nicotinamide phosphoribosyltransferase inhibitor
-
Olesen UH, Thougaard AV, Jensen PB, Sehested M. A preclinical study on the rescue of normal tissue by nicotinic acid in high-dose treatment with APO866, a specific nicotinamide phosphoribosyltransferase inhibitor. Mol. Cancer Ther. 9(6), 1609-1617 (2010).
-
(2010)
Mol. Cancer Ther.
, vol.9
, Issue.6
, pp. 1609-1617
-
-
Olesen, U.H.1
Thougaard, A.V.2
Jensen, P.B.3
Sehested, M.4
-
101
-
-
0033571407
-
CHS 828, a novel pyridyl cyanoguanidine with potent anti-Tumor activity in vitro and in vivo
-
Hjarnaa PJ, Jonsson E, Latini S et al. CHS 828, a novel pyridyl cyanoguanidine with potent anti-Tumor activity in vitro and in vivo. Cancer Res. 59(22), 5751-5757 (1999).
-
(1999)
Cancer Res.
, vol.59
, Issue.22
, pp. 5751-5757
-
-
Hjarnaa, P.J.1
Jonsson, E.2
Latini, S.3
-
102
-
-
84860258689
-
Coadministration of nicotinic acid with the Nampt inhibitor MPC-9528 enhances anti-Tumor activity in Naprt deficient cancer cells in culture and in xenografts
-
FL, USA 2-6 April
-
Fleischer TC, Baichwal VR, Boniface JJ et al. Coadministration of nicotinic acid with the Nampt inhibitor MPC-9528 enhances anti-Tumor activity in Naprt deficient cancer cells in culture and in xenografts. Presented at: AACR 102nd Annual Meeting. Orlando, FL, USA 2-6 April 2011.
-
(2011)
Presented at: AACR 102nd Annual Meeting. Orlando
-
-
Fleischer, T.C.1
Baichwal, V.R.2
Boniface, J.J.3
-
103
-
-
47649094272
-
Synthesis and biological evaluation of isosteric analogs of FK866, an inhibitor of NAD salvage
-
Galli U, Ercolano E, Carraro L et al. Synthesis and biological evaluation of isosteric analogs of FK866, an inhibitor of NAD salvage. ChemMedChem 3(5), 771-779 (2008).
-
(2008)
Chem. Med. Chem.
, vol.3
, Issue.5
, pp. 771-779
-
-
Galli, U.1
Ercolano, E.2
Carraro, L.3
-
104
-
-
67650314923
-
Crystal structure of Rattus norvegicus visfatin/PBEF/Nampt in complex with an FK866-based inhibitor
-
Kang GB, Bae MH, Kim MK, Im I, Kim YC, Eom SH. Crystal structure of Rattus norvegicus visfatin/PBEF/Nampt in complex with an FK866-based inhibitor. Molecules and Cells 27(6), 667-671 (2009).
-
(2009)
Molecules and Cells
, vol.27
, Issue.6
, pp. 667-671
-
-
Kang, G.B.1
Bae, M.H.2
Kim, M.K.3
Im, I.4
Kim, Y.C.5
Eom, S.H.6
-
105
-
-
79952281704
-
Design, synthesis and x-ray crystallographic study of NAmPRTase inhibitors as anti-cancer agents
-
You H, Youn H-S, Im I et al. Design, synthesis and x-ray crystallographic study of NAmPRTase inhibitors as anti-cancer agents. Eur. J. Med. Chem. 46(4), 1153-1164 (2011).
-
(2011)
Eur. J. Med. Chem.
, vol.46
, Issue.4
, pp. 1153-1164
-
-
You, H.1
Youn, H.-S.2
Im, I.3
-
106
-
-
0031472361
-
Novel cyanoguanidines with potent oral anti-Tumor activity
-
Schou C, Ottosen ER, Petersen HJ et al. Novel cyanoguanidines with potent oral anti-Tumor activity. Bioorg. Med. Chem. Lett. 7(24), 3095-3100 (1997).
-
(1997)
Bioorg. Med. Chem. Lett.
, vol.7
, Issue.24
, pp. 3095-3100
-
-
Schou, C.1
Ottosen, E.R.2
Petersen, H.J.3
-
107
-
-
0033571407
-
CHS 828, a novel pyridyl cyanoguanidine with potent anti-Tumor activity in vitro and in vivo
-
Vig Hjarnaa P-J, Jonsson E, Latini S et al. CHS 828, a novel pyridyl cyanoguanidine with potent anti-Tumor activity in vitro and in vivo. Cancer Res. 59(22), 5751-5757 (1999).
-
(1999)
Cancer Res.
, vol.59
, Issue.22
, pp. 5751-5757
-
-
Vig Hjarnaa, P.-J.1
Jonsson, E.2
Latini, S.3
-
108
-
-
0035951688
-
In vivo activity of CHS 828 on hollow-fibre cultures of primary human tumor cells from patients
-
Jonsson E, Friberg LE, Karlsson MO et al. In vivo activity of CHS 828 on hollow-fibre cultures of primary human tumor cells from patients. Cancer Lett. 162(2), 193-200 (2001).
-
(2001)
Cancer Lett.
, vol.162
, Issue.2
, pp. 193-200
-
-
Jonsson, E.1
Friberg, L.E.2
Karlsson, M.O.3
-
109
-
-
0035218022
-
Activity of CHS 828 in primary cultures of human hematological and solid tumors in vitro
-
Aleskog A, Bashir-Hassan S, Hovstadius P et al. Activity of CHS 828 in primary cultures of human hematological and solid tumors in vitro. Anticancer Drugs 12(10), 821-827 (2001).
-
(2001)
Anticancer Drugs
, vol.12
, Issue.10
, pp. 821-827
-
-
Aleskog, A.1
Bashir-Hassan, S.2
Hovstadius, P.3
-
110
-
-
70350538957
-
The Small Molecule GMX1778 is a potent inhibitor of NAD+ biosyn thesis: Strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors
-
Watson M, Roulston A, Blec L et al. The Small Molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: Strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors. Mol. Cell. Biol. 29(21), 5872-5888 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.29
, Issue.21
, pp. 5872-5888
-
-
Watson, M.1
Roulston, A.2
Blec, L.3
-
111
-
-
77951932803
-
Metronomic administration of the drug GMX1777, a cellular NAD synthesis inhibitor, results in neuroblastoma regression and vessel maturation without inducing drug resistance
-
Fuchs D, Rodriguez A, Eriksson S, Christofferson R, Sundberg C, Azarbayjani F. Metronomic administration of the drug GMX1777, a cellular NAD synthesis inhibitor, results in neuroblastoma regression and vessel maturation without inducing drug resistance. Intl J. Cancer 126(12), 2773-2789 (2010).
-
(2010)
Intl J. Cancer
, vol.126
, Issue.12
, pp. 2773-2789
-
-
Fuchs, D.1
Rodriguez, A.2
Eriksson, S.3
Christofferson, R.4
Sundberg, C.5
Azarbayjani, F.6
-
112
-
-
0032171607
-
Cell cycle effects of CB30865, a lipophilic quinazoline-based analog of the antifolate thymidylate synthase inhibitor ICI 198583 with an undefined mechanism of action
-
Skelton LA, Ormerod MG, Titley JC, Jackman AL. Cell cycle effects of CB30865, a lipophilic quinazoline-based analog of the antifolate thymidylate synthase inhibitor ICI 198583 with an undefined mechanism of action. Cytometry 33(1), 56-66 (1998).
-
(1998)
Cytometry
, vol.33
, Issue.1
, pp. 56-66
-
-
Skelton, L.A.1
Ormerod, M.G.2
Titley, J.C.3
Jackman, A.L.4
-
113
-
-
0032996591
-
A novel class of lipophilic quinazoline-based folic acid analogs: Cytotoxic agents with a folate-independent locus
-
Skelton LA, Ormerod MG, Titley J, Kimbell R, Brunton LA, Jackman AL. A novel class of lipophilic quinazoline-based folic acid analogs: Cytotoxic agents with a folate-independent locus. Br. J. Cancer 79(11-12), 1692-1701 (1999).
-
(1999)
Br. J. Cancer
, vol.79
, Issue.11-12
, pp. 1692-1701
-
-
Skelton, L.A.1
Ormerod, M.G.2
Titley, J.3
Kimbell, R.4
Brunton, L.A.5
Jackman, A.L.6
-
114
-
-
77953696907
-
Chemical proteomics identifies nampt as the target of CB30865, an orphan cytotoxic compound
-
Fleischer TC, Murphy BR, Flick JS et al. Chemical proteomics identifies nampt as the target of CB30865, an orphan cytotoxic compound. Chem. Biol. 17(6), 659-664 (2010).
-
(2010)
Chem. Biol.
, vol.17
, Issue.6
, pp. 659-664
-
-
Fleischer, T.C.1
Murphy, B.R.2
Flick, J.S.3
-
115
-
-
78650348764
-
Analogs of 4-[(7-Bromo-2-methyl-4-oxo-3H-quinazolin-6-yl)methylprop-2- ynylamino] -N-(3-pyridylmethyl)benzamide (CB-30865) as potent inhibitors of nicotinamide phosphoribosyltransferase (Nampt)
-
Lockman JW, Murphy BR, Zigar DF et al. Analogs of 4-[(7-Bromo-2-methyl-4- oxo-3H-quinazolin-6-yl)methylprop-2-ynylamino]-N-(3-pyridylmethyl)benzamide (CB-30865) as potent inhibitors of nicotinamide phosphoribosyltransferase (Nampt). J. Med.Chem. 53(24), 8734-8746 (2010).
-
(2010)
J. Med.Chem.
, vol.53
, Issue.24
, pp. 8734-8746
-
-
Lockman, J.W.1
Murphy, B.R.2
Zigar, D.F.3
-
116
-
-
84860258088
-
MPI-0486348: A novel inhibitor of nicotinamide phosphoribosyltransferase induces tumor regression in a preclinical model
-
Washington DC USA 17-21 April
-
Fleischer TC, Baichwal VR, Bradford CL et al. MPI-0486348: A novel inhibitor of nicotinamide phosphoribosyltransferase induces tumor regression in a preclinical model. Presented at: AACR 101st Annual Meeting. Washington DC, USA 17-21 April 2010.
-
(2010)
Presented at: AACR 101st Annual Meeting
-
-
Fleischer, T.C.1
Baichwal, V.R.2
Bradford, C.L.3
-
117
-
-
79952439080
-
A fluorometric assay for high-Throughput screening targeting nicotinamide phosphoribosyltransferase
-
Zhang R-Y, Qin Y, Lv X-Q et al. A fluorometric assay for high-Throughput screening targeting nicotinamide phosphoribosyltransferase. Anal. Biochem. 412(1), 18-25 (2011).
-
(2011)
Anal. Biochem.
, vol.412
, Issue.1
, pp. 18-25
-
-
Zhang, R.-Y.1
Qin, Y.2
Lv, X.-Q.3
-
118
-
-
74249085615
-
Natural phenolic compounds from medicinal herbs and dietary plants: Potential use for cancer prevention
-
Huang WY, Cai YZ, Zhang Y. Natural phenolic compounds from medicinal herbs and dietary plants: Potential use for cancer prevention. Nutr. Cancer 62(1), 1-20 (2010).
-
(2010)
Nutr. Cancer
, vol.62
, Issue.1
, pp. 1-20
-
-
Huang, W.Y.1
Cai, Y.Z.2
Zhang, Y.3
-
119
-
-
78649947146
-
Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase
-
Olesen UH, Petersen JG, Garten A et al. Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase. BMC Cancer 10, 677 (2010).
-
(2010)
BMC Cancer
, vol.10
, pp. 677
-
-
Olesen, U.H.1
Petersen, J.G.2
Garten, A.3
-
120
-
-
53049090681
-
Therapeutic T-cell manipulation in rheumatoid arthritis: Past, present and future
-
Isaacs JD. Therapeutic T-cell manipulation in rheumatoid arthritis: Past, present and future. Rheumatology (Oxford) 47(10), 1461-1468 (2008).
-
(2008)
Rheumatology (Oxford)
, vol.47
, Issue.10
, pp. 1461-1468
-
-
Isaacs, J.D.1
-
122
-
-
0036850176
-
Molecular mechanisms of sulfasalazine-induced T-cell apoptosis
-
Liptay S, Fulda S, Schanbacher M et al. Molecular mechanisms of sulfasalazine-induced T-cell apoptosis. Br. J. Pharmacol. 137(5), 608-620 (2002).
-
(2002)
Br. J. Pharmacol.
, vol.137
, Issue.5
, pp. 608-620
-
-
Liptay, S.1
Fulda, S.2
Schanbacher, M.3
-
124
-
-
84860258690
-
Basal NAD levels and Nampt expression correlate with in vitro and in vivo sensitivity of tumor cell lines to the Nampt inhibitor MPC09528
-
Orlando, FL, USA 2-6 April
-
Boniface JJ, Baichwal VR, Cimbora DM et al. Basal NAD levels and Nampt expression correlate with in vitro and in vivo sensitivity of tumor cell lines to the Nampt inhibitor MPC09528. Presented at: AACR 102nd Annual Meeting. Orlando, FL, USA, 2-6 April 2011.
-
(2011)
Presented at: AACR 102nd Annual Meeting
-
-
Boniface, J.J.1
Baichwal, V.R.2
Cimbora, D.M.3
-
125
-
-
84860258087
-
Pharmacokinetics, anti-Tumor activity and therapeutic index of Nampt inhibitor MPC-8640 in mice
-
San Francisco, CA, USA 12-16 November
-
Carlson RO, Willardsen JA, Lockman JW et al. Pharmacokinetics, anti-Tumor activity and therapeutic index of Nampt inhibitor MPC-8640 in mice. Presented at: AACR-NCI-EORTC International Conference. San Francisco, CA, USA, 12-16 November 2011.
-
(2011)
Presented at: AACR-NCI-EORTC International Conference
-
-
Carlson, R.O.1
Willardsen, J.A.2
Lockman, J.W.3
|