In vivo molecular imaging of experimental joint inflammation by combined 18F-FDG positron emission tomography and computed tomography

Arthritis Research and Therapy

Volumn 12, Issue 6, 2010, Pages

  Irmler, Ingo M ^a   Opfermann, Thomas ^b   Gebhardt, Peter ^b   Gajda, Mieczyslaw ^a   Bräuer, Rolf ^a   Saluz, Hans P ^b,c   Kamradt, Thomas ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b HANS KNÖLL INSTITUTE   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18; GLUCOSE 6 PHOSPHATE ISOMERASE; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; CARPAL JOINT; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; HISTOPATHOLOGY; IN VIVO STUDY; MOLECULAR IMAGING; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOISOTOPE DISTRIBUTION; TARSAL JOINT; VALIDITY; ANIMAL; DBA MOUSE; METHODOLOGY; RADIOGRAPHY; SCINTISCANNING; VALIDATION STUDY;

ANIMALS; ARTHRITIS, EXPERIMENTAL; FLUORODEOXYGLUCOSE F18; MICE; MICE, INBRED DBA; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 78049325660     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar3176     Document Type: Article

References (28)

1. Cornelius P, Marlowe M, Pekala PH. Regulation of glucose transport by tumor necrosis factor-alpha in cultured murine 3T3-L1 fibroblasts. J Trauma 1990, 30(12 Suppl):S15-S20. 10.1097/00005373-199012001-00006, 2123942.
2. Gamelli RL, Liu H, He LK, Hofmann CA. Augmentations of glucose uptake and glucose transporter-1 in macrophages following thermal injury and sepsis in mice. J Leukoc Biol 1996, 59:639-647.
3. Matsui T, Nakata N, Nagai S, Nakatani A, Takahashi M, Momose T, Ohtomo K, Koyasu S. Inflammatory cytokines and hypoxia contribute to 18F-FDG uptake by cells involved in pannus formation in rheumatoid arthritis. J Nucl Med 2009, 50:920-926. 10.2967/jnumed.108.060103, 19443596.
4. Yamada S, Kubota K, Kubota R, Ido T, Tamahashi N. High accumulation of fluorine-18-fluorodeoxyglucose in turpentine-induced inflammatory tissue. J Nucl Med 1995, 36:1301-1306.
5. Jones HA, Cadwallader KA, White JF, Uddin M, Peters AM, Chilvers ER. Dissociation between respiratory burst activity and deoxyglucose uptake in human neutrophil granulocytes: implications for interpretation of (18)F-FDG PET images. J Nucl Med 2002, 43:652-657.
6. Deichen JT, Prante O, Gack M, Schmiedehausen K, Kuwert T. Uptake of [18F]fluorodeoxyglucose in human monocyte-macrophages in vitro. Eur J Nucl Med Mol Imaging 2003, 30:267-273. 10.1007/s00259-002-1018-8, 12552345.
7. Palmer WE, Rosenthal DI, Schoenberg OI, Fischman AJ, Simon LS, Rubin RH, Polisson RP. Quantification of inflammation in the wrist with gadolinium-enhanced MR imaging and PET with 2-[F-18]-fluoro-2-deoxy-D-glucose. Radiology 1995, 196:647-655.
8. Beckers C, Ribbens C, Andre B, Marcelis S, Kaye O, Mathy L, Kaiser MJ, Hustinx R, Foidart J, Malaise MG. Assessment of disease activity in rheumatoid arthritis with (18)F-FDG PET. J Nucl Med 2004, 45:956-964.
9. Olafsen T, Betting D, Kenanova VE, Salazar FB, Clarke P, Said J, Raubitschek AA, Timmerman JM, Wu AM. Recombinant anti-CD20 antibody fragments for small-animal PET imaging of B-cell lymphomas. J Nucl Med 2009, 50:1500-1508. 10.2967/jnumed.108.060426, 2852538, 19690034.
10. Vogel WV, van Riel PL, Oyen WJ. FDG-PET/CT can visualise the extent of inflammation in rheumatoid arthritis of the tarsus. Eur J Nucl Med Mol Imaging 2007, 34:439. 10.1007/s00259-006-0246-8, 17048035.
11. Schubert D, Maier B, Morawietz L, Krenn V, Kamradt T. Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered mice. J Immunol 2004, 172:4503-4509.
12. Bockermann R, Schubert D, Kamradt T, Holmdahl R. Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase. Arthritis Res Ther 2005, 7:R1316-1324. 10.1186/ar1829, 1297579, 16277685.
13. Iwanami K, Matsumoto I, Tanaka Y, Inoue A, Goto D, Ito S, Tsutsumi A, Sumida T. Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis. Arthritis Res Ther 2008, 10:R130. 10.1186/ar2545, 2656230, 18992137.
14. Matsumoto I, Zhang H, Yasukochi T, Iwanami K, Tanaka Y, Inoue A, Goto D, Ito S, Tsutsumi A, Sumida T. Therapeutic effects of antibodies to tumor necrosis factor-alpha, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis. Arthritis Res Ther 2008, 10:R66. 10.1186/ar2437, 2483457, 18534002.
15. Tanaka-Watanabe Y, Matsumoto I, Iwanami K, Inoue A, Goto D, Ito S, Tsutsumi A, Sumida T. B cells play a crucial role as antigen-presenting cells and collaborate with inflammatory cytokines in glucose-6-phosphate isomerase-induced arthritis. Clin Exp Immunol 2009, 155:285-294. 10.1111/j.1365-2249.2008.03816.x, 2675260, 19032549.
16. Frey O, Meisel J, Hutloff A, Bonhagen K, Bruns L, Kroczek RA, Morawietz L, Kamradt T. Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis. Ann Rheum Dis 2010, 69:1495-1501. 10.1136/ard.2009.119164, 20498202.
17. Frey O, Reichel A, Bonhagen K, Morawietz L, Rauchhaus U, Kamradt T. Regulatory T cells control the transition from acute into chronic inflammation in glucose-6-phosphate isomerase-induced arthritis. Ann Rheum Dis 2010, 69:1511-1518. 10.1136/ard.2009.123422, 20498199.
18. Boettger MK, Hensellek S, Richter F, Gajda M, Stockigt R, von Banchet GS, Brauer R, Schaible HG. Antinociceptive effects of tumor necrosis factor alpha neutralization in a rat model of antigen-induced arthritis: evidence of a neuronal target. Arthritis Rheum 2008, 58:2368-2378. 10.1002/art.23608, 18668541.
19. Constantinescu CC, Mukherjee J. Performance evaluation of an Inveon PET preclinical scanner. Phys Med Biol 2009, 54:2885-2899. 10.1088/0031-9155/54/9/020, 2838767, 19384008.
20. Visser EP, Disselhorst JA, Brom M, Laverman P, Gotthardt M, Oyen WJ, Boerman OC. Spatial resolution and sensitivity of the Inveon small-animal PET scanner. J Nucl Med 2009, 50:139-147. 10.2967/jnumed.108.055152, 19139188.
21. Brenner M, Braun C, Oster M, Gulko PS. Thermal signature analysis as a novel method for evaluating inflammatory arthritis activity. Ann Rheum Dis 2006, 65:306-311. 10.1136/ard.2004.035246, 1798043, 16150784.
22. Hoffmann MH, Hopf R, Niederreiter B, Redl H, Smolen JS, Steiner G. Gait changes precede overt arthritis and strongly correlate with symptoms and histopathological events in pristane-induced arthritis. Arthritis Res Ther 2010, 12:R41. 10.1186/ar2950, 2888188, 20222952.
23. Vincelette J, Xu Y, Zhang LN, Schaefer CJ, Vergona R, Sullivan ME, Hampton TG, Wang YX. Gait analysis in a murine model of collagen-induced arthritis. Arthritis Res Ther 2007, 9:R123. 10.1186/ar2331, 2246242, 18036238.
24. Barrera P, Oyen WJ, Boerman OC, van Riel PL. Scintigraphic detection of tumour necrosis factor in patients with rheumatoid arthritis. Ann Rheum Dis 2003, 62:825-828. 10.1136/ard.62.9.825, 1754647, 12922953.
25. Martins FP, Gutfilen B, de Souza SA, de Azevedo MN, Cardoso LR, Fraga R, da Fonseca LM. Monitoring rheumatoid arthritis synovitis with 99mTc-anti-CD3. Br J Radiol 2008, 81:25-29. 10.1259/bjr/63780400, 18039720.
26. Chapman PT, Jamar F, Keelan ET, Peters AM, Haskard DO. Use of a radiolabeled monoclonal antibody against E-selectin for imaging of endothelial activation in rheumatoid arthritis. Arthritis Rheum 1996, 39:1371-1375. 10.1002/art.1780390815, 8702446.
27. Jamar F, Houssiau FA, Devogelaer JP, Chapman PT, Haskard DO, Beaujean V, Beckers C, Manicourt DH, Peters AM. Scintigraphy using a technetium 99m-labelled anti-E-selectin Fab fragment in rheumatoid arthritis. Rheumatology (Oxford) 2002, 41:53-61. 10.1093/rheumatology/41.1.53, 11792880.
28. Conti F, Priori R, Chimenti MS, Coari G, Annovazzi A, Valesini G, Signore A. Successful treatment with intraarticular infliximab for resistant knee monarthritis in a patient with spondylarthropathy: a role for scintigraphy with 99mTc-infliximab. Arthritis Rheum 2005, 52:1224-1226. 10.1002/art.20979, 15818709.