Antigen persistence is required for somatic mutation and affinity maturation of immunoglobulin

European Journal of Immunology

Volumn 30, Issue 8, 2000, Pages 2226-2234

  Wang, Yang ^a   Huang, Guangming ^b   Wang, Jing ^a   Molina, Hector ^b   Chaplin, David D ^b   Fu, Yang Xin ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Affinity maturation; Follicular dendritic cell; Germinal center; Lymphotoxin; Tumor

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN;

ANTIBODY AFFINITY; ANTIGEN SPECIFICITY; ANTIGENICITY; ARTICLE; B LYMPHOCYTE; DENDRITIC CELL; GENE EXPRESSION; GERMINAL CENTER; HAPTEN CARRIER COMPLEX; IMMUNIZATION; MATURATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOMATIC MUTATION; T LYMPHOCYTE;

ANIMALS; ANTIBODY AFFINITY; ANTIBODY FORMATION; ANTIGENS; ANTIGENS, CD; BASE SEQUENCE; DENDRITIC CELLS; GERMINAL CENTER; IMMUNOGLOBULIN CLASS SWITCHING; LYMPHOTOXIN-ALPHA; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUTATION; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I;

EID: 0033838426     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(2000)30:8<2226::AID-IMMU2226>3.0.CO;2-5     Document Type: Article

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