The dendritic tree and brain disorders

Molecular and Cellular Neuroscience

Volumn 50, Issue 1, 2012, Pages 10-20

  Kulkarni, Vaishali A ^a   Firestein, Bonnie L ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANXIETY; AUTISM; BIOCHEMISTRY; BIPOLAR DISORDER; BRAIN DISEASE; BRAIN FUNCTION; CELL MATURATION; CELL STRUCTURE; DEMENTIA; DENDRITE; DOWN SYNDROME; FRAGILE X SYNDROME; HUMAN; MENTAL DEFICIENCY; NERVE CELL DIFFERENTIATION; NERVE FIBER; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; RETT SYNDROME; REVIEW; SCHIZOPHRENIA; STRESS; SYNAPSE;

ANIMALS; AXONS; BRAIN; CYTOSKELETON; DENDRITES; HUMANS; MENTAL DISORDERS; MICE; NERVOUS SYSTEM DISEASES; SYNAPSES;

EID: 84859638601     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2012.03.005     Document Type: Review

References (244)

1. Agarwala K.L., Ganesh S., Suzuki T., Akagi T., Kaneko K., Amano K., Tsutsumi Y., Yamaguchi K., Hashikawa T., Yamakawa K. Dscam is associated with axonal and dendritic features of neuronal cells. J. Neurosci. Res. 2001, 66:337-346.
2. Ahnert-Hilger G., Holtje M., Grosse G., Pickert G., Mucke C., Nixdorf-Bergweiler B., Boquet P., Hofmann F., Just I. Differential effects of Rho GTPases on axonal and dendritic development in hippocampal neurones. J. Neurochem. 2004, 90:9-18.
3. Akhmanova A., Hoogenraad C.C., Drabek K., Stepanova T., Dortland B., Verkerk T., Vermeulen W., Burgering B.M., De Zeeuw C.I., Grosveld F., Galjart N. Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts. Cell 2001, 104:923-935.
4. Akum B.F., Chen M., Gunderson S.I., Riefler G.M., Scerri-Hansen M.M., Firestein B.L. Cypin regulates dendrite patterning in hippocampal neurons by promoting microtubule assembly. Nat. Neurosci. 2004, 7:145-152.
5. Al-Bassam J., Chang F. Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP. Trends Cell Biol. 2011, 21:604-614.
6. Al-Bassam J., Kim H., Brouhard G., van Oijen A., Harrison S.C., Chang F. CLASP promotes microtubule rescue by recruiting tubulin dimers to the microtubule. Dev. Cell 2010, 19:245-258.
7. Alves-Sampaio A., Troca-Marin J.A., Montesinos M.L. NMDA-mediated regulation of DSCAM dendritic local translation is lost in a mouse model of Down's syndrome. J. Neurosci.: Off. J. Soc. Neurosci. 2010, 30:13537-13548.
8. Anderton B.H., Callahan L., Coleman P., Davies P., Flood D., Jicha G.A., Ohm T., Weaver C. Dendritic changes in Alzheimer's disease and factors that may underlie these changes. Prog. Neurobiol. 1998, 55:595-609.
9. Antar L.N., Afroz R., Dictenberg J.B., Carroll R.C., Bassell G.J. Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses. J. Neurosci.: Off. J. Soc. Neurosci. 2004, 24:2648-2655.
10. Arimura N., Kaibuchi K. Key regulators in neuronal polarity. Neuron 2005, 48:881-884.
11. Armstrong D. Recent developments in neuropathology-electron microscopy-brain pathology. Eur. Child Adolesc. Psychiatry 1997, 6(Suppl. 1):69-70.
12. Armstrong D.D. Rett syndrome neuropathology review 2000. Brain Dev. 2001, 23(Suppl. 1):S72-S76.
13. Armstrong D., Dunn J.K., Antalffy B., Trivedi R. Selective dendritic alterations in the cortex of Rett syndrome. J. Neuropathol. Exp. Neurol. 1995, 54:195-201.
14. Armstrong D.D., Dunn K., Antalffy B. Decreased dendritic branching in frontal, motor and limbic cortex in Rett syndrome compared with trisomy 21. J. Neuropathol. Exp. Neurol. 1998, 57:1013-1017.
15. Arnal I., Heichette C., Diamantopoulos G.S., Chrétien D. CLIP-170/tubulin-curved oligomers coassemble at microtubule ends and promote rescues. Curr. Biol. 2004, 14:2086-2095.
16. Baas P.W., Lin S. Hooks and comets: the story of microtubule polarity orientation in the neuron. Dev. Neurobiol. 2011, 71:403-418.
17. Baas P.W., Deitch J.S., Black M.M., Banker G.A. Polarity orientation of microtubules in hippocampal neurons: uniformity in the axon and nonuniformity in the dendrite. Proc. Natl. Acad. Sci. U. S. A. 1988, 85:8335-8339.
18. Baas P.W., Black M.M., Banker G.A. Changes in microtubule polarity orientation during the development of hippocampal neurons in culture. J. Cell Biol. 1989, 109:3085-3094.
19. Bacon J.P., Murphey R.K. Receptive fields of cricket giant interneurones are related to their dendritic structure. J. Physiol. 1984, 352:601-623.
20. Barenfel'd L.S. Down syndrome: pathogenesis, radioresistant DNA synthesis and chromosomal instability. Tsitologiia 2002, 44:379-386.
21. Bassell G.J., Warren S.T. Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function. Neuron 2008, 60:201-214.
22. Becker L.E., Armstrong D.L., Chan F. Dendritic atrophy in children with Down's syndrome. Ann. Neurol. 1986, 20:520-526.
23. Becker L., Mito T., Takashima S., Onodera K. Growth and development of the brain in Down syndrome. Prog. Clin. Biol. Res. 1991, 373:133-152.
24. Belichenko P.V.O.A., Hagberg B., Dahlström A. Rett syndrome: 3-D confocal microscopy of cortical pyramidal dendrites and afferents. Neuroreport 1994, 5:1509-1513.
25. Benavides-Piccione R., Ballesteros-Yanez I., de Lagran M.M., Elston G., Estivill X., Fillat C., Defelipe J., Dierssen M. On dendrites in Down syndrome and DS murine models: a spiny way to learn. Prog. Neurobiol. 2004, 74:111-126.
26. Bennett M. Positive and negative symptoms in schizophrenia: the NMDA receptor hypofunction hypothesis, neuregulin/ErbB4 and synapse regression. Aust. N. Z. J. Psychiatry 2009, 43:711-721.
27. Bianchi M., Hagan J.J., Heidbreder C.A. Neuronal plasticity, stress and depression: involvement of the cytoskeletal microtubular system?. Curr. Drug Targets CNS Neurol. Disord. 2005, 4:597-611.
28. Black M.M., Baas P.W. The basis of polarity in neurons. Trends Neurosci. 1989, 12:211-214.
29. Blanpied T.A., Ehlers M.D. Microanatomy of dendritic spines: emerging principles of synaptic pathology in psychiatric and neurological disease. Biol. Psychiatry 2004, 55:1121-1127.
30. Bongmba O.Y., Martinez L.A., Elhardt M.E., Butler K., Tejada-Simon M.V. Modulation of dendritic spines and synaptic function by Rac1: a possible link to Fragile X syndrome pathology. Brain Res. 2011, 1399:79-95.
31. Bosc C., Cronk J.D., Pirollet F., Watterson D.M., Haiech J., Job D., Margolis R.I. Cloning, expression and properties of the microtubule stabilizing protein STOP. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:2125-2130.
32. Bosco A., Linden R. BDNF and NT-4 differentially modulate neurite outgrowth in developing retinal ganglion cells. J. Neurosci. Res. 1999, 57:759-769.
33. Bourne J.N., Harris K.M. Balancing structure and function at hippocampal dendritic spines. Annu. Rev. Neurosci. 2008, 31:47-67.
34. Braak E., Braak H. Alzheimer's disease: transiently developing dendritic changes in pyramidal cells of sector CA1 of the Ammon's horn. Acta Neuropathol. 1997, 93:323-325.
35. Broadbelt K., Byne W., Jones L.B. Evidence for a decrease in basilar dendrites of pyramidal cells in schizophrenic medial prefrontal cortex. Schizophr. Res. 2002, 58:75-81.
36. Brzustowicz L.M., Simone J., Mohseni P., Hayter J.E., Hodgkinson K.A., Chow E.W., Bassett A.S. Linkage disequilibrium mapping of schizophrenia susceptibility to the CAPON region of chromosome 1q22. Am. J. Hum. Genet. 2004, 74:1057-1063.
37. Burton P.R. Dendrites of mitral cell neurons contain microtubules of opposite polarity. Brain Res. 1988, 473:107-115.
38. Cajal S.R. Textura del sistema nervioso del hombre y de los vertebrados 1899-1904, Madrid Imprenta y Librera de Nicols Moya.
39. Calabresi P., Picconi B., Parnetti L., Di Filippo M. A convergent model for cognitive dysfunctions in Parkinson's disease: the critical dopamine-acetylcholine synaptic balance. Lancet Neurol. 2006, 5:974-983.
40. Campbell D.B., D'Oronzio R., Garbett K., Ebert P.J., Mirnics K., Levitt P., Persico A.M. Disruption of cerebral cortex MET signaling in autism spectrum disorder. Ann. Neurol. 2007, 62:243-250.
41. Carrel D., Du Y., Komlos D., Hadzimichalis N.M., Kwon M., Wang B., Brzustowicz L.M., Firestein B.L. NOS1AP regulates dendrite patterning of hippocampal neurons through a carboxypeptidase E-mediated pathway. J. Neurosci.: Off. J. Soc. Neurosci. 2009, 29:8248-8258.
42. Casanova M.F. Functional and anatomical aspects of prefrontal pathology in schizophrenia. Schizophr. Bull. 1997, 23:517-519.
43. Casanova M.F., Goldberg T.E., Suddath R.L., Daniel D.G., Rawlings R., Lloyd D.G., Loats H.L., Kleinman J.E., Weinberger D.R. Quantitative shape analysis of the temporal and prefrontal lobes of schizophrenic patients: a magnetic resonance image study. J. Neuropsychiatry Clin. Neurosci. 1990, 2:363-372.
44. Chapleau C.A., Calfa G.D., Lane M.C., Albertson A.J., Larimore J.L., Kudo S., Armstrong D.L., Percy A.K., Pozzo-Miller L. Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations. Neurobiol. Dis. 2009, 35:219-233.
45. Charych E.I., Akum B.F., Goldberg J.S., Jornsten R.J., Rongo C., Zheng J.Q., Firestein B.L. Activity-independent regulation of dendrite patterning by postsynaptic density protein PSD-95. J. Neurosci.: Off. J. Soc. Neurosci. 2006, 26:10164-10176.
46. Chen H., Firestein B.L. RhoA regulates dendrite branching in hippocampal neurons by decreasing cypin protein levels. J. Neurosci. 2007, 27:8378-8386.
47. Chen J., Magavi S.S., Macklis J.D. Neurogenesis of corticospinal motor neurons extending spinal projections in adult mice. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:16357-16362.
48. Chen S.X., Tari P.K., She K., Haas K. Neurexin-neuroligin cell adhesion complexes contribute to synaptotropic dendritogenesis via growth stabilization mechanisms in vivo. Neuron 2010, 67:967-983.
49. Cheng L., Mao Y. mDia3-EB1-APC: a connection between kinetochores and microtubule plus ends. Commun. Integr. Biol. 2011, 4:480-482.
50. Cline H.T. Dendritic arbor development and synaptogenesis. Curr. Opin. Neurobiol. 2001, 11:118-126.
51. Coleman P.D., Flood D.G. Neuron numbers and dendritic extent in normal aging and Alzheimer's disease. Neurobiol. Aging 1987, 8:521-545.
52. Conrad C.D., McLaughlin K.J., Harman J.S., Foltz C., Wieczorek L., Lightner E., Wright R.L. Chronic glucocorticoids increase hippocampal vulnerability to neurotoxicity under conditions that produce CA3 dendritic retraction but fail to impair spatial recognition memory. J. Neurosci.: Off. J. Soc. Neurosci. 2007, 27:8278-8285.
53. Cooper M.W., Smith S.J. A real-time analysis of growth cone-target cell interactions during the formation of stable contacts between hippocampal neurons in culture. J. Neurobiol. 1992, 23:814-828.
54. Couch B.A., DeMarco G.J., Gourley S.L., Koleske A.J. Increased dendrite branching in AbetaPP/PS1 mice and elongation of dendrite arbors by fasudil administration. J. Alzheimers Dis. 2010, 20:1003-1008.
55. Craig A.M., Banker G. Neuronal polarity. Annu. Rev. Neurosci. 1994, 17:267-310.
56. Crossin K.L., Krushel L.A. Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily. Developmental Dynamics : An Official Publication of the American Association of Anatomists 2000, 218:260-279.
57. Cubelos B., Sebastian-Serrano A., Beccari L., Calcagnotto M.E., Cisneros E., Kim S., Dopazo A., Alvarez-Dolado M., Redondo J.M., Bovolenta P., Walsh C.A., Nieto M. Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex. Neuron 2010, 66:523-535.
58. Dahlhaus R., El-Husseini A. Altered neuroligin expression is involved in social deficits in a mouse model of the fragile X syndrome. Behav. Brain Res. 2010, 208:96-105.
59. Dailey M.E., Smith S.J. The dynamics of dendritic structure in developing hippocampal slices. J. Neurosci.: Off. J. Soc. Neurosci. 1996, 16:2983-2994.
60. Danzer S.C., Kotloski R.J., Walter C., Hughes M., McNamara J.O. Altered morphology of hippocampal dentate granule cell presynaptic and postsynaptic terminals following conditional deletion of TrkB. Hippocampus 2008, 18:668-678.
61. De Rubeis S., Bagni C. Fragile X mental retardation protein control of neuronal mRNA metabolism: insights into mRNA stability. Mol. Cell. Neurosci. 2010, 43:43-50.
62. de Ruiter J.P., Uylings H.B. Morphometric and dendritic analysis of fascia dentata granule cells in human aging and senile dementia. Brain Res. 1987, 402:217-229.
63. Dehmelt L., Halpain S. The MAP2/Tau family of microtubule-associated proteins. Genome Biol. 2005, 6:204.
64. Dent E.W., Barnes A.M., Tang F., Kalil K. Netrin-1 and semaphorin 3A promote or inhibit cortical axon branching, respectively, by reorganization of the cytoskeleton. J. Neurosci.: Off. J. Soc. Neurosci. 2004, 24:3002-3012.
65. Diamantopoulos G.S., Perez F., Goodson H.V., Batelier G., Melki R., Kreis T.E., Rickard J.E. Dynamic localization of CLIP-170 to microtubule plus ends is coupled to microtubule assembly. J. Cell Biol. 1999, 11:99-112.
66. Dickstein D.L., Brautigam H., Stockton S.D., Schmeidler J., Hof P.R. Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau. Brain Struct. Funct. 2010, 214:161-179.
67. Dierssen M., de Lagran M.M. DYRK1A (dual-specificity tyrosine-phosphorylated and -regulated kinase 1A): a gene with dosage effect during development and neurogenesis. Sci. World J. 2006, 6:1911-1922.
68. Dijkhuizen P.A., Ghosh A. BDNF regulates primary dendrite formation in cortical neurons via the PI3-kinase and MAP kinase signaling pathways. J. Neurobiol. 2005, 62:278-288.
69. Dolen G., Bear M.F. Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome. J. Physiol. 2008, 586:1503-1508.
70. Dowjat W.K., Adayev T., Kuchna I., Nowicki K., Palminiello S., Hwang Y.W., Wegiel J. Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome. Neurosci. Lett. 2007, 413:77-81.
71. Drabek K., van Ham M., Stepanova T., Draegestein K., van Horssen R., Sayas C.L., Akhmanova A., Ten Hagen T., Smits R., Fodde R., Grosveld F., Galjart N. Role of CLASP2 in microtubule stabilization and the regulation of persistent motility. Curr. Biol. 2006, 16:2259-2264.
72. Durand C.M., Perroy J., Loll F., Perrais D., Fagni L., Bourgeron T., Montcouquiol M., Sans N. SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism. Mol. Psychiatry 2012, 17:71-84.
73. Eiland L., McEwen B.S. Early life stress followed by subsequent adult chronic stress potentiates anxiety and blunts hippocampal structural remodeling. Hippocampus 2012, 22:82-91.
74. el Hachimi K.H., Foncin J.F. Loss of dendritic spines in Alzheimer's disease. C. R. Acad. Sci. III 1990, 311:397-402.
75. Elston G.N. Cortex, cognition and the cell: new insights into the pyramidal neuron and prefrontal function. Cereb. Cortex 2003, 13:1124-1138.
76. Emsley J.G., Mitchell B.D., Kempermann G., Macklis J.D. Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells. Prog. Neurobiol. 2005, 75:321-341.
77. Engert F.B.T. Dendritic spine changes associated with hippocampal long term plasticity. Nat. Cell Biol. 1999, 399:66-70.
78. Feng Y., Gutekunst C.A., Eberhart D.E., Yi H., Warren S.T., Hersch S.M. Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes. J. Neurosci.: Off. J. Soc. Neurosci. 1997, 17:1539-1547.
79. Fiala J., Feinberg M., Popov V., Harris K.M. Synaptogenesis via dendritic filopodia in developing hippocampal area CA1. J. Neurosci. 1998, 18:8900-8911.
80. Fischer M., K.S., Knutti D., Matus A. Rapid actin-based plasticity in dendritic spines. Neuron 1998, 20:847-854.
81. Flood D.G. Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. II. Subiculum. Brain Res. 1991, 540:83-95.
82. Flood D.G., Guarnaccia M., Coleman P.D. Dendritic extent in human CA2-3 hippocampal pyramidal neurons in normal aging and senile dementia. Brain Res. 1987, 409:88-96.
83. Folker E.S., Baker B., Goodson H.V. Interactions between CLIP-170, tubulin, and microtubules: implications for the mechanism of Clip-170 plus-end tracking behavior. Mol. Biol. Cell 2005, 16:5373-5384.
84. Fombonne E. The epidemiology of autism: a review. Psychol. Med. 1999, 29:769-786.
85. Fombonne E. Epidemiological surveys of autism and other pervasive developmental disorders: an update. J. Autism Dev. Disord. 2003, 33:365-382.
86. Fombonne E. Epidemiology of autistic disorder and other pervasive developmental disorders. J. Clin. Psychiatry 2005, 66(Suppl. 10):3-8.
87. Franklin J.L., Berechid B.E., Cutting F.B., Presente A., Chambers C.B., Foltz D.R., Ferreira A., Nye J.S. Autonomous and non-autonomous regulation of mammalian neurite development by Notch 1 and Delta1. Curr. Biol. 1999, 9:1448-1457.
88. Friedlander S., Pothier P., Morrison D., Herman L. The role of neurological-developmental delay in childhood psychopathology. Am. J. Orthopsychiatry 1982, 52:102-108.
89. Fukuda T., Itoh M., Ichikawa T., Washiyama K., Goto Y. Delayed maturation of neuronal architecture and synaptogenesis in cerebral cortex of Mecp2-deficient mice. J. Neuropathol. Exp. Neurol. 2005, 64:537-544.
90. Galjart N. Plus-end-tracking proteins and their interactions at microtubule ends. Curr. Biol. 2010, 20:R528-R537.
91. Garber K.B., Visootsak J., Warren S.T. Fragile X syndrome. Eur. J. Hum. Genet. 2008, 16:666-672.
92. Garey L. When cortical development goes wrong: schizophrenia as a neurodevelopmental disease of microcircuits. J. Anat. 2010, 217:324-333.
93. Garey L.J., Ong W.Y., Patel T.S., Kanani M., Davis A., Mortimer A.M., Barnes T.R., Hirsch S.R. Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia. J. Neurol. Neurosurg. Psychiatry 1998, 65:446-453.
94. Garey L.J., Von Bussmann K.A., Hirsch S.R. Decreased numerical density of kainate receptor-positive neurons in the orbitofrontal cortex of chronic schizophrenics. Exp. Brain Res. 2006, 173:234-242.
95. Georges P.C., Hadzimichalis N.M., Sweet E.S., Firestein B.L. The yin-yang of dendrite morphology: unity of actin and microtubules. Mol. Neurobiol. 2008, 38:270-284.
96. Giacometti E., Luikenhuis S., Beard C., Jaenisch R. Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:1931-1936.
97. Glantz L.A., Lewis D.A. Reduction of synaptophysin immunoreactivity in the prefrontal cortex of subjects with schizophrenia. Regional and diagnostic specificity. Arch. Gen. Psychiatry 1997, 54:943-952.
98. Glantz L.A., Lewis D.A. Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch. Gen. Psychiatry 2000, 57:65-73.
99. Glantz L.A., Lewis D.A. Dendritic spine density in schizophrenia and depression. Arch. Gen. Psychiatry 2001, 58:203.
100. Goedert M., Crowther R.A., Garner C.C. Molecular characterization of microtubule-associated proteins tau and MAP2. Trends Neurosci. 1991, 14:193-199.
101. Golden J.A., Hyman B.T. Development of the superior temporal neocortex is anomalous in trisomy 21. J. Neuropathol. Exp. Neurol. 1994, 53:513-520.
102. Gonzales M.L., LaSalle J.M. The role of MeCP2 in brain development and neurodevelopmental disorders. Curr. Psychiatry Rep. 2010, 12:127-134.
103. Goslin K., Schreyer D.J., Skene J.H., Banker G. Development of neuronal polarity: GAP-43 distinguishes axonal from dendritic growth cones. Nature 1988, 336:672-674.
104. Gu J., Zheng J.Q. Microtubules in dendritic spine development and plasticity. Open Neurosci. J. 2009, 3:128-133.
105. Gu J., Firestein B.L., Zheng J.Q. Microtubules in dendritic spine development. J. Neurosci.: Off. J. Soc. Neurosci. 2008, 28:12120-12124.
106. Guillaud L., Bosc C., Fourest-Lieuvin A., Denarier E., Pirollet F., Lafanechère L., Job D. STOP proteins are responsible for the high degree of microtubule stabilization observed in neuronal cells. J. Cell Biol. 1998, 13:167-179.
107. Gutierrez H., Dolcet X., Tolcos M., Davies A. HGF regulates the development of cortical pyramidal dendrites. Development 2004, 131:3717-3726.
108. Hageman I., Nielsen M., Wortwein G., Diemer N.H., Jorgensen M.B. Electroconvulsive stimulations prevent stress-induced morphological changes in the hippocampus. Stress (Amsterdam, Neth.) 2008, 11:282-289.
109. Hagerman R., Hoem G., Hagerman P. Fragile X and autism: intertwined at the molecular level leading to targeted treatments. Mol. Autism 2010, 1:12.
110. Hall H., Bozic D., Fauser C., Engel J. Trimerization of cell adhesion molecule L1 mimics clustered L1 expression on the cell surface: influence on L1-ligand interactions and on promotion of neurite outgrowth. J. Neurochem. 2000, 75:336-346.
111. Halpain S., Dehmelt L. The MAP1 family of microtubule-associated proteins. Genome Biol. 2006, 7:224.
112. Hammerle B., Carnicero A., Elizalde C., Ceron J., Martinez S., Tejedor F.J. Expression patterns and subcellular localization of the Down syndrome candidate protein MNB/DYRK1A suggest a role in late neuronal differentiation. Eur. J. Neurosci. 2003, 17:2277-2286.
113. Han G., Liu B., Zhang J., Zuo W., Morris N.R., Xiang X. The Aspergillus cytoplasmic dynein heavy chain and NUDF localize to microtubule ends and affect microtubule dynamics. Curr. Biol. 2001, 11:719-724.
114. Hanks S.D., Flood D.G. Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. I. CA1 of hippocampus. Brain Res. 1991, 540:63-82.
115. Harris K.M. Structure, development, and plasticity of dendritic spines. Curr. Opin. Neurobiol. 1999, 9:343-348.
116. Harrison P.J., McLaughlin D., Kerwin R.W. Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. Lancet 1991, 337:450-452.
117. Harvey I., Ron M.A., Du Boulay G., Wicks D., Lewis S.W., Murray R.M. Reduction of cortical volume in schizophrenia on magnetic resonance imaging. Psychol. Med. 1993, 23:591-604.
118. Hashimoto K., Iyo M. Glutamate hypothesis of schizophrenia and targets for new antipsychotic drugs. Nihon Shinkei Seishin Yakurigaku Zasshi 2002, 22:3-13.
119. Hassold T.J., Jacobs P.A. Trisomy in man. Annu. Rev. Genet. 1984, 18:69-97.
120. Hill J.J., Hashimoto T., Lewis D.A. Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia. Mol. Psychiatry 2006, 11:557-566.
121. Hirsch S.R., Das I., Garey L.J., de Belleroche J. A pivotal role for glutamate in the pathogenesis of schizophrenia, and its cognitive dysfunction. Pharmacol. Biochem. Behav. 1997, 56:797-802.
122. Honnappa S., Gouveia S., Weisbrich A., Damberger F.F., Bhavesh N.S., Jawhari H., Grigoriev I., van Rijssel F.J., Buey R.M., Lawera A., Jelesarov I., Winkler F.K., Wüthrich K., Akhmanova A., Steinmetz M.O. An EB1-binding motif acts as a microtubule tip localization signal. Cell 2009, 138:366-376.
123. Hu X., Viesselmann C., Nam S., Merriam E., Dent E.W. Activity-dependent dynamic microtubule invasion of dendritic spines. J. Neurosci.: Off. J. Soc. Neurosci. 2008, 28:13094-13105.
124. Hutsler J.J., Zhang H. Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders. Brain Res. 2010, 1309:83-94.
125. Huttenlocher P.R. Dendritic development and mental defect. Neurology 1970, 20:381.
126. Ichtchenko K., Nguyen T., Sudhof T.C. Structures, alternative splicing, and neurexin binding of multiple neuroligins. J. Biol. Chem. 1996, 271:2676-2682.
127. Itoh M., Ide S., Takashima S., Kudo S., Nomura Y., Segawa M., Kubota T., Mori H., Tanaka S., Horie H., Tanabe Y., Goto Y. Methyl CpG-binding protein 2 (a mutation of which causes Rett syndrome) directly regulates insulin-like growth factor binding protein 3 in mouse and human brains. J. Neuropathol. Exp. Neurol. 2007, 66:117-123.
128. Jamain S., Quach H., Betancur C., Rastam M., Colineaux C., Gillberg I.C., Soderstrom H., Giros B., Leboyer M., Gillberg C., Bourgeron T. Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nat. Genet. 2003, 34:27-29.
129. Jaworski J., Kapitein L.C., Gouveia S.M., Dortland B.R., Wulf P.S., Grigoriev I., Camera P., Spangler S.A., Di Stefano P., Demmers J., Krugers H., Defilippi P., Akhmanova A., Hoogenraad C.C. Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron 2009, 61:85-100.
130. Jellinger K., Seitelberger F. Neuropathology of Rett syndrome. Am. J. Med. Genet. Suppl. 1986, 1:259-288.
131. Jentarra G.M., Olfers S.L., Rice S.G., Srivastava N., Homanics G.E., Blue M., Naidu S., Narayanan V. Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation. BMC Neurosci. 2010, 11:19.
132. Job D., Rauch C.T., Fischer E.H., Margolis R.L. Recycling of cold-stable microtubules: evidence that cold stability is due to substoichiometric polymer blocks. Biochem. Cell Biol. 1982, 21:509-515.
133. Jontes J.D., Smith S.J. Filopodia, spines, and the generation of synaptic diversity. Neuron 2000, 27:11-14.
134. Jontes J.D., Buchanan J., Smith S.J. Growth cone and dendrite dynamics in zebrafish embryos: early events in synaptogenesis imaged in vivo. Nat. Neurosci. 2000, 3:231-237.
135. Jugloff D.G., Jung B.P., Purushotham D., Logan R., Eubanks J.H. Increased dendritic complexity and axonal length in cultured mouse cortical neurons overexpressing methyl-CpG-binding protein MeCP2. Neurobiol. Dis. 2005, 19:18-27.
136. Kant G.J., Leu J.R., Anderson S.M., Mougey E.H. Effects of chronic stress on plasma corticosterone, ACTH and prolactin. Physiol. Behav. 1987, 40:775-779.
137. Kapitein L.C., Yau K.W., Hoogenraad C.C. Microtubule dynamics in dendritic spines. Methods Cell Biol. 2010, 97:111-132.
138. Kauer J.A., Malenka R.C. Synaptic plasticity and addiction. Nat. Rev. Neurosci. 2007, 8:844-858.
139. Kaufmann W.E., Moser H.W. Dendritic anomalies in disorders associated with mental retardation. Cereb. Cortex 2000, 10:981-991.
140. Kaufmann W.E., Naidu S., Budden S. Abnormal expression of microtubule-associated protein 2 (MAP-2) in neocortex in Rett syndrome. Neuropediatrics 1995, 26:109-113.
141. Kaufmann W.E., Taylor C.V., Hohmann C.F., Sanwal I.B., Naidu S. Abnormalities in neuronal maturation in Rett syndrome neocortex: preliminary molecular correlates. Eur. Child Adolesc. Psychiatry 1997, 6(Suppl. 1):75-77.
142. Kemper T.L. Neuropathology of Down syndrome. The Psychobiology of Down Syndrome 1988, 269-289. MIT, Cambridge, M.A. L. Nadel (Ed.).
143. Kentrup H., Joost H.G., Heimann G., Becker W. Minibrain/DYRK1A gene: candidate gene for mental retardation in Down's syndrome?. Klin. Padiatr. 2000, 212:60-63.
144. Kita K., Wittmann T., Näthke I.S., Waterman-Storer C.M. Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1. Mol. Biol. Cell 2006, 17:2331-2345.
145. Kobayashi T., Shiroguchi K., Edamatsu M., Toyoshima Y.Y. Microtubule-binding properties of dynactin p150 expedient for dynein motility. Biochem. Biophys. Res. Commun. 2006, 340:23-28.
146. Kolluri N., Sun Z., Sampson A.R., Lewis D.A. Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia. Am. J. Psychiatry 2005, 162:1200-1202.
147. Kolomeets N.S., Orlovskaya D.D., Rachmanova V.I., Uranova N.A. Ultrastructural alterations in hippocampal mossy fiber synapses in schizophrenia: a postmortem morphometric study. Synapse (New York, N.Y.) 2005, 57:47-55.
148. Kolomeets N.S., Orlovskaya D.D., Uranova N.A. Decreased numerical density of CA3 hippocampal mossy fiber synapses in schizophrenia. Synapse (New York, N.Y.) 2007, 61:615-621.
149. Kremeyer B., Garcia J., Kymalainen H., Wratten N., Restrepo G., Palacio C., Miranda A.L., Lopez C., Restrepo M., Bedoya G., Brzustowicz L.M., Ospina-Duque J., Arbelaez M.P., Ruiz-Linares A. Evidence for a role of the NOS1AP (CAPON) gene in schizophrenia and its clinical dimensions: an association study in a South American population isolate. Hum. Hered. 2009, 67:163-173.
150. Kwan A.C., Dombeck D.A., Webb W.W. Polarized microtubule arrays in apical dendrites and axons. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:11370-11375.
151. Kwon M., Fernandez J.R., Zegarek Gregory F., Lo Sean B., Firestein Bonnie L. BDNF-promoted increases in proximal dendrite occur via CREB-dependent transcriptional regulation of Cypin. J. Neurosci. 2011, 31:9735-9745.
152. Laifenfeld D., Klein E., Ben-Shachar D. Norepinephrine alters the expression of genes involved in neuronal sprouting and differentiation: relevance for major depression and antidepressant mechanisms. J. Neurochem. 2002, 83:1054-1064.
153. Larimore J.L., Chapleau C.A., Kudo S., Theibert A., Percy A.K., Pozzo-Miller L. Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations. Neurobiol. Dis. 2009, 34:199-211.
154. Lau C.G., Zukin R.S. NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nat. Rev. Neurosci. 2007, 8:413-426.
155. Li Z., Van Aelst L., Cline H.T. Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo. Nat. Neurosci. 2000, 3:217-225.
156. Li N., Zhao C.T., Wang Y., Yuan X.B. The transcription factor Cux1 regulates dendritic morphology of cortical pyramidal neurons. PLoS One 2010, 5:e10596.
157. Magavi S.S., Leavitt B.R., Macklis J.D. Induction of neurogenesis in the neocortex of adult mice. Nature 2000, 405:951-955.
158. Maletic-Savatic M., Malinow R., Svoboda K. Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity. Science 1999, 283:1923-1927.
159. Marin-Padilla M. Structural abnormalities of the cerebral cortex in human chromosomal aberrations: a Golgi study. Brain Res. 1972, 44:625-629.
160. Marin-Padilla M. Pyramidal cell abnormalities in the motor cortex of a child with Down's syndrome. A Golgi study. J. Comp. Neurol. 1976, 167:63-81.
161. McAllister A.K. Cellular and molecular mechanisms of dendrite growth. Cereb. Cortex 2000, 10:963-973.
162. McAllister A.K., Lo D.C., Katz L.C. Neurotrophins regulate dendritic growth in developing visual cortex. Neuron 1995, 15:791-803.
163. McAllister A.K., Katz L.C., Lo D.C. Neurotrophin regulation of cortical dendritic growth requires activity. Neuron 1996, 17:1057-1064.
164. McAllister A.K., Katz L.C., Lo D.C. Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth. Neuron 1997, 18:767-778.
165. Mehraein P., Yamada M., Tarnowska-Dziduszko E. Quantitative study on dendrites and dendritic spines in Alzheimer's disease and senile dementia. Adv. Neurol. 1975, 12:453-458.
166. Mimori-Kiyosue Y., Shiina N., Tsukita S. The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubules. Curr. Biol. 2000, 10:865-868.
167. Mimori-Kiyosue Y., Grigoriev I., Lansbergen G., Sasaki H., Matsui C., Severin F., Galjart N., Grosveld F., Vorobjev I., Tsukita S., Akhmanova A. CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. J. Cell Biol. 2005, 168:141-153.
168. Mueller B.K., Mack H., Teusch N. Rho kinase, a promising drug target for neurological disorders. Nat. Rev. Drug Discov. 2005, 4:387-398.
169. Muhle R., Trentacoste S.V., Rapin I. The genetics of autism. Pediatrics 2004, 13:e472-e486.
170. Nakayama A.Y., Harms M.B., Luo L. Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons. J. Neurosci.: Off. J. Soc. Neurosci. 2000, 20:5329-5338.
171. Niblock M.M., Brunso-Bechtold J.K., Riddle D.R. Insulin-like growth factor I stimulates dendritic growth in primary somatosensory cortex. J. Neurosci. 2000, 20:4165-4176.
172. Niell C.M., Meyer M.P., Smith S.J. In vivo imaging of synapse formation on a growing dendritic arbor. Nat. Neurosci. 2004, 7:254-260.
173. O'Donnell W.T., Warren S.T. A decade of molecular studies of fragile X syndrome. Annu. Rev. Neurosci. 2002, 25:315-338.
174. Ong W.Y., Garey L.J. Ultrastructural features of biopsied temporopolar cortex (area 38) in a case of schizophrenia. Schizophr. Res. 1993, 10:15-27.
175. Parrish J.Z., Emoto K., Kim M.D., Jan Y.N. Mechanisms that regulate establishment, maintenance, and remodeling of dendritic fields. Annu. Rev. Neurosci. 2007, 30:399-423.
176. Perez F., Diamantopoulos G., Stalder R., Kreis T.E. CLIP-170 highlights growing microtubule ends in vivo. Cell 1999, 19:517-527.
177. Persico A.M., Bourgeron T. Searching for ways out of the autism maze: genetic, epigenetic and environmental clues. Trends Neurosci. 2006, 29:349-358.
178. Petralia R.S., Wang Y.X., Wenthold R.J. The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J. Neurosci.: Off. J. Soc. Neurosci. 1994, 14:6102-6120.
179. Petratos S., Li Q.X., George A.J., Hou X., Kerr M.L., Unabia S.E., Hatzinisiriou I., Maksel D., Aguilar M.I., Small D.H. The beta-amyloid protein of Alzheimer's disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism. Brain: J. Neurol. 2008, 131:90-108.
180. Pfeiffer B.E., Huber K.M. Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation. J. Neurosci.: Off. J. Soc. Neurosci. 2007, 27:3120-3130.
181. Pilpel Y., Segal M. Activation of PKC induces rapid morphological plasticity in dendrites of hippocampal neurons via Rac and Rho-dependent mechanisms. Eur. J. Neurosci. 2004, 19:3151-3164.
182. Polleux F., Morrow T., Ghosh A. Semaphorin 3A is a chemoattractant for cortical apical dendrites. Nat. Neurosci. 2000, 404:567-573.
183. Poulain F.E., Sobel A. The microtubule network and neuronal morphogenesis: dynamic and coordinated orchestration through multiple players. Mol. Cell. Neurosci. 2010, 43:15-32.
184. Powell E.M., Muhlfriedel S., Bolz J., Levitt P. Differential regulation of thalamic and cortical axonal growth by hepatocyte growth factor/scatter factor. Dev. Neurosci. 2003, 25:197-206.
185. Prichard L., Deloulmes J.C., Storm D.R. Interactions between neurogranin and calmodulin in vivo. J. Biol. Chem. 1999, 274:7689-7694.
186. Prinz M., Prinz B., Schulz E. The growth of non-pyramidal neurons in the primary motor cortex of man: a Golgi study. Histol. Histopathol. 1997, 12:895-900.
187. Purpura D.P. Dendritic spine "dysgenesis" and mental retardation. Science 1974, 186:1126-1128.
188. Radley J.J., Sisti H.M., Hao J., Rocher A.B., McCall T., Hof P.R., McEwen B.S., Morrison J.H. Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex. Neuroscience 2004, 125:1-6.
189. Rajan I., Cline H.T. Glutamate receptor activity is required for normal development of tectal cell dendrites in vivo. J. Neurosci.: Off. J. Soc. Neurosci. 1998, 18:7836-7846.
190. Rapin I. Autism. N. Engl. J. Med. 1997, 337:97-104.
191. Raymond G.V., Bauman M.L., Kemper T.L. Hippocampus in autism: a Golgi analysis. Acta Neuropathol. 1996, 91:117-119.
192. Raz N., Torres I.J., Briggs S.D., Spencer W.D., Thornton A.E., Loken W.J., Gunning F.M., McQuain J.D., Driesen N.R., Acker J.D. Selective neuroanatomic abnormalities in Down's syndrome and their cognitive correlates: evidence from MRI morphometry. Neurology 1995, 45:356-366.
193. Redmond L., Ghosh A. The role of Notch and Rho GTPase signaling in the control of dendritic development. Curr. Opin. Neurobiol. 2001, 11:111-117.
194. Redmond L., Oh S.R., Hicks C., Weinmaster G., Ghosh A. Nuclear Notch1 signaling and the regulation of dendritic development. Nat. Neurosci. 2000, 3:30-40.
195. Ruchhoeft M.L., Ohnuma S., McNeill L., Holt C.E., Harris W.A. The neuronal architecture of Xenopus retinal ganglion cells is sculpted by rho-family GTPases in vivo. J. Neurosci. 1999, 19:8454-8463.
196. Rudelli R.D., B.W., Wisniewski K., Jenkins E.C., Laure-Kamionowska M., Connell F., Wisniewski H.M. Adult fragile X syndrome. Cliniconeuropathologic findings. Acta Neuropathol. 1985, 67:289-295.
197. Salama-Cohen P., Arevalo M.A., Meier J., Grantyn R., Rodriguez-Tebar A. NGF controls dendrite development in hippocampal neurons by binding to p75NTR and modulating the cellular targets of Notch. Mol. Biol. Cell 2005, 16:339-347.
198. Salama-Cohen P., Arevalo M.A., Grantyn R., Rodriguez-Tebar A. Notch and NGF/p75NTR control dendrite morphology and the balance of excitatory/inhibitory synaptic input to hippocampal neurones through Neurogenin 3. J. Neurochem. 2006, 97:1269-1278.
199. Sandblad L., Busch K., Tittmann P., Gross H., Brunner D., Hoenger A. The Schizosaccharomyces pombe EB1 homolog Mal3p binds and stabilizes the microtubule lattice seam. Cell 2006, 127:1415-1424.
200. Sapolsky R.M. Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch. Gen. Psychiatry 2000, 57:925-935.
201. Sapolsky R.M., Uno H., Rebert C.S., Finch C.E. Hippocampal damage associated with prolonged glucocorticoid exposure in primates. J. Neurosci.: Off. J. Soc. Neurosci. 1990, 10:2897-2902.
202. Schulz E., Scholz B. Neurohistological findings in the parietal cortex of children with chromosome aberrations. J. Hirnforsch. 1992, 33:37-62.
203. Schumann C.M., Hamstra J., Goodlin-Jones B.L., Lotspeich L.J., Kwon H., Buonocore M.H., Lammers C.R., Reiss Amaral D.G. The amygdala is enlarged in children but not adolescents with autism; the hippocampus is enlarged at all ages. J. Neurosci. 2004, 24:6392-6640.
204. Schuyler S.C., Pellman D. Microtubule "plus-end-tracking proteins": the end is just the beginning. Cell 2001, 105:421-424.
205. Selemon L.D., Rajkowska G., Goldman-Rakic P.S. Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17. Arch. Gen. Psychiatry 1995, 52:805-818. discussion 819-820.
206. Selkoe D.J. Alzheimer's disease is a synaptic failure. Science 2002, 298(5594):789-791.
207. Simon-Areces J., Dopazo A., Dettenhofer M., Rodriguez-Tebar A., Garcia-Segura L.M., Arevalo M.A. Formin1 mediates the induction of dendritogenesis and synaptogenesis by neurogenin3 in mouse hippocampal neurons. PLoS One 2011, 6:e21825.
208. Siuciak J.A., Lewis D.R., Wiegand S.J., Lindsay R.M. Antidepressant-like effect of brain-derived neurotrophic factor(BDNF). Pharmacol. Biochem. Behav. 1997, 56:131-137.
209. Slaughter T., Black M. STOP (stable-tubule-only-polypeptide) is preferentially associated with the stable domain of axonal microtubules. J. Neurocytol. 2003, 32:399-413.
210. Smith M.A., Makino S., Kvetnanskv R., Post R. Stress alters the express of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. J. Neurosci. 1995, 15:l768-l1777.
211. Soetanto A., Wilson R.S., Talbot K., Un A., Schneider J.A., Sobiesk M., Kelly J., Leurgans S., Bennett D.A., Arnold S.E. Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans. Arch. Gen. Psychiatry 2010, 67:448-457.
212. Song J.Y., Ichtchenko K., Sudhof T.C., Brose N. Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:1100-1105.
213. Sousa N., Lukoyanov N.V., Madeira M.D., Almeida O.F., Paula-Barbosa M.M. Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement. Neuroscience 2000, 97:253-266.
214. Stein-Behrens B., Mattson M.P., Chang I., Yeh M., Sapolsky R. Stress exacerbates neuron loss and cytoskeletal pathology in the hippocampus. J. Neurosci.: Off. J. Soc. Neurosci. 1994, 14:5373-5380.
215. Stephan K.E., Baldeweg T., Friston K.J. Synaptic plasticity and dysconnection in schizophrenia. Biol. Psychiatry 2006, 59:929-939.
216. Stephan K.E., Friston K.J., Frith C.D. Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring. Schizophr. Bull. 2009, 35:509-527.
217. Suddath R.L., Casanova M.F., Goldberg T.E., Daniel D.G., Kelsoe J.R., Weinberger D.R. Temporal lobe pathology in schizophrenia: a quantitative magnetic resonance imaging study. Am. J. Psychiatry 1989, 146:464-472.
218. Sudhof T.C. Neuroligins and neurexins link synaptic function to cognitive disease. Nature 2008, 455:903-911.
219. Sweet E.S., Tseng C.Y., Firestein B.L. To branch or not to branch: how PSD-95 regulates dendrites and spines. Bioarchitecture 2011, 1:69-73.
220. Tabuchi K., Blundell J., Etherton M.R., Hammer R.E., Liu X., Powell C.M., Sudhof T.C. A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science 2007, 318:71-76.
221. Takashima S., Ieshima A., Nakamura H., Becker L.E. Dendrites, dementia and the Down syndrome. Brain Dev. 1989, 11:131-133.
222. Tata D.A., Anderson B.J. The effects of chronic glucocorticoid exposure on dendritic length, synapse numbers and glial volume in animal models: implications for hippocampal volume reductions in depression. Physiol. Behav. 2010, 99:186-193.
223. Taupin P. Consideration of adult neurogenesis from basic science to therapy. Med. Sci. Monit. 2005, 11:LE16-LE17.
224. Taupin P. Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells. Int. J. Med. Sci. 2008, 5:127-132.
225. Tejedor F.J., Hammerle B. MNB/DYRK1A as a multiple regulator of neuronal development. FEBS J. 2011, 278:223-235.
226. Terry R.D., Masliah E., Salmon D.P., Butters N., DeTeresa R., Hill R., Hansen L.A., Katzman R. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann. Neurol. 1991, 30:572-580.
227. Timpl R.J.B. The laminins. Matrix Biol.: J. Int. Soc. Matrix Biol. 1994, 14:13729-13732.
228. Uno H., Tarara R., Else J.G., Suleman M.A., Sapolsky R.M. Hippocampal damage associated with prolonged and fatal stress in primates. J. Neurosci.: Off. J. Soc. Neurosci. 1989, 9:1705-1711.
229. Van Aelst L., Cline H.T. Rho GTPases and activity-dependent dendrite development. Curr. Opin. Neurobiol. 2004, 14:297-304.
230. Verkerk A.J., Pieretti M., Sutcliffe J.S., Fu Y.H., Kuhl D.P., Pizzuti A., Reiner O., Richards S., Victoria M.F., Zhang F.P., et al. Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell 1991, 65:905-914.
231. Wadsworth W.G. Moving around in a worm: netrin UNC-6 and circumferential axon guidance in C. elegans. Trends Neurosci. 2002, 25:423-429.
232. Warner-Schmidt J.L., Duman R.S. Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus 2006, 16:239-249.
233. Whitford K.L., Marillat V., Stein E., Goodman C.S., Tessier-Lavigne M., Chedotal A., Ghosh A. Regulation of cortical dendrite development by Slit-Robo interactions. Neuron 2002, 33:47-61.
234. Wisniewski K.E.a.K.E. Abnormal neurogenesis and synaptogenesisin Down syndrome brain. Dev. Brain Dysfunct. 1994, 7:289-301.
235. Woolley C.S., Gould E., McEwen B.S. Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons. Brain Res. 1990, 531:225-231.
236. Young E.A., Haskett R.F., Murphy-Weinberg V., Watson S.J., Akil H. Loss of glucocorticoid fast feedback in depression. Arch. Gen. Psychiatry 1991, 48:693-699.
237. 2+ elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J. Neurosci.: Off. J. Soc. Neurosci. 2010, 30:11938-11950.
238. Zhang C., Milunsky J.M., Newton S., Ko J., Zhao G., Maher T.A., Tager-Flusberg H., Bolliger M.F., Carter A.S., Boucard A.A., Powell C.M., Sudhof T.C. A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export. J. Neurosci.: Off. J. Soc. Neurosci. 2009, 29:10843-10854.
239. Zheng Y., Wildonger J., Ye B., Zhang Y., Kita A., Younger S.H., Zimmerman S., Jan L.Y., Jan Y.N. Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons. Nat. Cell Biol. 2008, 10:1172-1180.
240. Zhou Z., Hong E.J., Cohen S., Zhao W.N., Ho H.Y., Schmidt L., Chen W.G., Lin Y., Savner E., Griffith E.C., Hu L., Steen J.A., Weitz C.J., Greenberg M.E. Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation. Neuron 2006, 52:255-269.
241. Zipursky R.B., Lim K.O., Sullivan E.V., Brown B.W., Pfefferbaum A. Widespread cerebral gray matter volume deficits in schizophrenia. Arch. Gen. Psychiatry 1992, 49:195-205.
242. Ziv N.E., Smith S.J. Evidence for a role of dendritic filopodia in synaptogenesis and spine formation. Neuron 1996, 17:91-102.
243. Zoghbi H.Y. Postnatal neurodevelopmental disorders: meeting at the synapse?. Science 2003, 302:826-830.
244. Zumbrunn J., Kinoshita K., Hyman A.A., Näthke I.S. Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation. Curr. Biol. 2001, 11:44-49.