Increased dendrite branching in AβPP/PS1 mice and elongation of dendrite arbors by fasudil administration

Journal of Alzheimer's Disease

Volumn 20, Issue 4, 2010, Pages 1003-1008

  Couch, Brian A ^a   Demarco, George J ^a   Gourley, Shannon L ^a,b   Koleske, Anthony J ^a,b  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amyloid protein precursor; dendrites; fasudil; hippocampus; intracerebroventricular infusion; presenilin 1; Rho GTPase; Rho kinase

Indexed keywords

AMYLOID PRECURSOR PROTEIN; FASUDIL; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ENZYME INHIBITOR; PRESENILIN 1; PROTEIN KINASE INHIBITOR; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DENDRITE; GENE OVEREXPRESSION; GENETIC REGULATION; MORPHOMETRICS; MOUSE; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PYRAMIDAL NERVE CELL; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENETICS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; NERVE CELL; PHYSIOLOGY; ULTRASTRUCTURE;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; DENDRITES; ENZYME INHIBITORS; INJECTIONS, INTRAVENTRICULAR; MICE; MICE, TRANSGENIC; NEURONS; PRESENILIN-1; PROTEIN KINASE INHIBITORS; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES;

EID: 77954546832     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-091114     Document Type: Article

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