메뉴 건너뛰기




Volumn 27, Issue 31, 2007, Pages 8278-8285

Chronic glucocorticoids increase hippocampal vulnerability to neurotoxicity under conditions that produce CA3 dendritic retraction but fail to impair spatial recognition memory

Author keywords

Corticosterone; Dendritic arborization; Depression; Exploration; Glucocorticoid; Hippocampus; Ibotenic acid; Learning and memory; Neuronal death; Rat; Recognition memory; Stress

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID; PHENYTOIN;

EID: 34547689480     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2121-07.2007     Document Type: Article
Times cited : (129)

References (42)
  • 2
    • 0029974277 scopus 로고    scopus 로고
    • The effects of chronic corticosterone on memory performance in the platform maze task
    • Bardgett ME, Newcomer JW, Taylor GT (1996) The effects of chronic corticosterone on memory performance in the platform maze task. Physiol Behav 59:1111-1115.
    • (1996) Physiol Behav , vol.59 , pp. 1111-1115
    • Bardgett, M.E.1    Newcomer, J.W.2    Taylor, G.T.3
  • 3
    • 0028858985 scopus 로고
    • Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats
    • Bodnoff SR, Humphreys AG, Lehman JC, Diamond DM, Rose GM, Meaney MJ (1995) Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats. J Neurosci 15:61-69.
    • (1995) J Neurosci , vol.15 , pp. 61-69
    • Bodnoff, S.R.1    Humphreys, A.G.2    Lehman, J.C.3    Diamond, D.M.4    Rose, G.M.5    Meaney, M.J.6
  • 4
    • 0038077367 scopus 로고    scopus 로고
    • Chronic administration of corticosterone impairs spatial reference memory before spatial working memory in rats
    • Coburn-Litvak PS, Pothakos K, Tata DA, McCloskey DP, Anderson BJ (2003) Chronic administration of corticosterone impairs spatial reference memory before spatial working memory in rats. Neurobiol Learn Mem 80:11-23.
    • (2003) Neurobiol Learn Mem , vol.80 , pp. 11-23
    • Coburn-Litvak, P.S.1    Pothakos, K.2    Tata, D.A.3    McCloskey, D.P.4    Anderson, B.J.5
  • 7
    • 0030447110 scopus 로고    scopus 로고
    • Chronic stress impairs rat spatial memory on the Y-maze, and this effect is blocked by tianeptine pretreatment
    • Conrad CD, Galea LA, Kuroda Y, McEwen BS (1996) Chronic stress impairs rat spatial memory on the Y-maze, and this effect is blocked by tianeptine pretreatment. Behav Neurosci 110:1321-1334.
    • (1996) Behav Neurosci , vol.110 , pp. 1321-1334
    • Conrad, C.D.1    Galea, L.A.2    Kuroda, Y.3    McEwen, B.S.4
  • 8
    • 0032838203 scopus 로고    scopus 로고
    • Support for a biomodal role for type II adrenal steroid receptors in spatial memory
    • Conrad CD, Lupien SJ, McEwen BS (1999a) Support for a biomodal role for type II adrenal steroid receptors in spatial memory. Neurobiol Learn Mem 72:39-46.
    • (1999) Neurobiol Learn Mem , vol.72 , pp. 39-46
    • Conrad, C.D.1    Lupien, S.J.2    McEwen, B.S.3
  • 9
    • 0343750698 scopus 로고    scopus 로고
    • Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy
    • Conrad CD, Magariños AM, LeDoux JE, McEwen BS (1999b) Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy. Behav Neurosci 113:902-913.
    • (1999) Behav Neurosci , vol.113 , pp. 902-913
    • Conrad, C.D.1    Magariños, A.M.2    LeDoux, J.E.3    McEwen, B.S.4
  • 10
    • 1842826385 scopus 로고    scopus 로고
    • Chronic stress enhances ibotenic acid-induced damage selectively within the hippocampal CA3 region of male, but not female rats
    • Conrad CD, Jackson JL, Wise L (2004) Chronic stress enhances ibotenic acid-induced damage selectively within the hippocampal CA3 region of male, but not female rats. Neuroscience 125:759-767.
    • (2004) Neuroscience , vol.125 , pp. 759-767
    • Conrad, C.D.1    Jackson, J.L.2    Wise, L.3
  • 11
    • 0027368053 scopus 로고
    • Cognitive deficits induced in young rats by long-term corticosterone administration
    • Dachir S, Kadar T, Robinzon B, Levy A (1993) Cognitive deficits induced in young rats by long-term corticosterone administration. Behav Neural Biol 60:103-109.
    • (1993) Behav Neural Biol , vol.60 , pp. 103-109
    • Dachir, S.1    Kadar, T.2    Robinzon, B.3    Levy, A.4
  • 12
    • 0029023666 scopus 로고
    • Nimodipine counteracts corticosterone-induced habituation impairments
    • Dachir S, Robinzon B, Grauer E, Levy A (1995) Nimodipine counteracts corticosterone-induced habituation impairments. Neurobiol Learn Mem 63:241-245.
    • (1995) Neurobiol Learn Mem , vol.63 , pp. 241-245
    • Dachir, S.1    Robinzon, B.2    Grauer, E.3    Levy, A.4
  • 13
    • 0012346476 scopus 로고    scopus 로고
    • Hypothalamo-pituitary-adrenal axis
    • Fink G, ed, pp, San Diego: Academic
    • Dallman MF, Bhatnagar S, Via V (2000) Hypothalamo-pituitary-adrenal axis. In: Encyclopedia of stress, Vol 2 (Fink G, ed), pp 468-477. San Diego: Academic.
    • (2000) Encyclopedia of stress , vol.2 , pp. 468-477
    • Dallman, M.F.1    Bhatnagar, S.2    Via, V.3
  • 14
    • 0037123750 scopus 로고    scopus 로고
    • 17b-Estradiol treatment retards excitotoxic delayed degeneration in substantia nigra reticulata neurons
    • DeGiorgio LA, Attardi B, Shimizu Y, Ogata M, Volpe BT (2002) 17b-Estradiol treatment retards excitotoxic delayed degeneration in substantia nigra reticulata neurons. Brain Res 936:15-20.
    • (2002) Brain Res , vol.936 , pp. 15-20
    • DeGiorgio, L.A.1    Attardi, B.2    Shimizu, Y.3    Ogata, M.4    Volpe, B.T.5
  • 15
    • 20044395965 scopus 로고    scopus 로고
    • Stress and the brain: From adaptation to disease
    • de Kloet ER, Joëls M, Holsboer F (2005) Stress and the brain: from adaptation to disease. Nat Rev 6:463-475.
    • (2005) Nat Rev , vol.6 , pp. 463-475
    • de Kloet, E.R.1    Joëls, M.2    Holsboer, F.3
  • 16
    • 21044434915 scopus 로고    scopus 로고
    • Rheumatoid arthritis: An overview of new and emerging therapies
    • Doan T, Massarotti E (2005) Rheumatoid arthritis: an overview of new and emerging therapies. J Clin Pharmacol 45:751-762.
    • (2005) J Clin Pharmacol , vol.45 , pp. 751-762
    • Doan, T.1    Massarotti, E.2
  • 17
    • 0030065554 scopus 로고    scopus 로고
    • Impairment of maze learning in rats following long-term glucocorticoid treatments
    • Endo Y, Nishimura J, Kimura F (1996) Impairment of maze learning in rats following long-term glucocorticoid treatments. Neurosci Lett 203:199-202.
    • (1996) Neurosci Lett , vol.203 , pp. 199-202
    • Endo, Y.1    Nishimura, J.2    Kimura, F.3
  • 18
    • 0024592102 scopus 로고
    • The dendritic morphology of pyramidal neurons in the rat hippocampal CA3 area. I. Cell types
    • Fitch JM, Juraska JM, Washington LW (1989) The dendritic morphology of pyramidal neurons in the rat hippocampal CA3 area. I. Cell types. Brain Res 479:105-114.
    • (1989) Brain Res , vol.479 , pp. 105-114
    • Fitch, J.M.1    Juraska, J.M.2    Washington, L.W.3
  • 19
    • 0024444808 scopus 로고
    • On the use of ibotenic acid to lesion selectively different components of the hippocampal formation
    • Jarrard LE (1989) On the use of ibotenic acid to lesion selectively different components of the hippocampal formation. J Neurosci Methods 29:251-259.
    • (1989) J Neurosci Methods , vol.29 , pp. 251-259
    • Jarrard, L.E.1
  • 20
    • 33746224915 scopus 로고    scopus 로고
    • Chronic stress impairs spatial memory and motivation for reward without disrupting motor ability and motivation to explore
    • Kleen JK, Sitomer MT, Killeen PR, Conrad CD (2006) Chronic stress impairs spatial memory and motivation for reward without disrupting motor ability and motivation to explore. Behav Neurosci 120:842-851.
    • (2006) Behav Neurosci , vol.120 , pp. 842-851
    • Kleen, J.K.1    Sitomer, M.T.2    Killeen, P.R.3    Conrad, C.D.4
  • 21
    • 0018263702 scopus 로고
    • Hippocampal aging and adrenocorticoids: Quantitative correlations
    • Landfield PW, Waymire JC, Lynch G (1978) Hippocampal aging and adrenocorticoids: quantitative correlations. Science 202:1098-1102.
    • (1978) Science , vol.202 , pp. 1098-1102
    • Landfield, P.W.1    Waymire, J.C.2    Lynch, G.3
  • 22
    • 0027287607 scopus 로고
    • Effects of chronic corticosterone ingestion on spatial memory performance and hippocampal serotonergic function
    • Luine VN, Spencer RL, McEwen BS (1993) Effects of chronic corticosterone ingestion on spatial memory performance and hippocampal serotonergic function. Brain Res 616:65-70.
    • (1993) Brain Res , vol.616 , pp. 65-70
    • Luine, V.N.1    Spencer, R.L.2    McEwen, B.S.3
  • 23
    • 0029146057 scopus 로고
    • Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Comparison of stressors
    • Magariños AM, McEwen BS (1995a) Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: comparison of stressors. Neuroscience 69:83-88.
    • (1995) Neuroscience , vol.69 , pp. 83-88
    • Magariños, A.M.1    McEwen, B.S.2
  • 24
    • 0029120661 scopus 로고
    • Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Involvement of glucocorticoid secretion and excitatory amino acid receptors
    • Magariños AM, McEwen BS (1995b) Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Involvement of glucocorticoid secretion and excitatory amino acid receptors. Neuroscience 69:89-98.
    • (1995) Neuroscience , vol.69 , pp. 89-98
    • Magariños, A.M.1    McEwen, B.S.2
  • 25
    • 0342621693 scopus 로고    scopus 로고
    • Morphological changes in the hippocampal CA3 region induced by non-invasive glucocorticoid administration: A paradox
    • Magariños AM, Orchinik M, McEwen BS (1998) Morphological changes in the hippocampal CA3 region induced by non-invasive glucocorticoid administration: a paradox. Brain Res 809:314-318.
    • (1998) Brain Res , vol.809 , pp. 314-318
    • Magariños, A.M.1    Orchinik, M.2    McEwen, B.S.3
  • 26
    • 0034667292 scopus 로고    scopus 로고
    • Effects of adverse experiences on brain structure and function
    • McEwen BS (2000) Effects of adverse experiences on brain structure and function. Biol Psychiatry 48:721-731.
    • (2000) Biol Psychiatry , vol.48 , pp. 721-731
    • McEwen, B.S.1
  • 27
    • 34447558468 scopus 로고    scopus 로고
    • The effects of chronic stress on hippocampal morphology and function: An evaluation of chronic restraint paradigms
    • McLaughlin KJ, Gomez J, Baran SE, Conrad CD (2007) The effects of chronic stress on hippocampal morphology and function: an evaluation of chronic restraint paradigms. Brain Res 1161:56-64.
    • (2007) Brain Res , vol.1161 , pp. 56-64
    • McLaughlin, K.J.1    Gomez, J.2    Baran, S.E.3    Conrad, C.D.4
  • 28
    • 18244421615 scopus 로고    scopus 로고
    • Chronic corticosterone impairs memory performance in the Barnes maze
    • McLay RN, Freeman SM, Zadina JE (1998) Chronic corticosterone impairs memory performance in the Barnes maze. Physiol Behav 63:933-937.
    • (1998) Physiol Behav , vol.63 , pp. 933-937
    • McLay, R.N.1    Freeman, S.M.2    Zadina, J.E.3
  • 29
    • 0035666488 scopus 로고    scopus 로고
    • Do glucocorticoids contribute to brain aging?
    • Nichols NR, Zieba M, Bye N (2001) Do glucocorticoids contribute to brain aging? Brain Res Rev 37:273-286.
    • (2001) Brain Res Rev , vol.37 , pp. 273-286
    • Nichols, N.R.1    Zieba, M.2    Bye, N.3
  • 31
    • 0032928466 scopus 로고    scopus 로고
    • Corticosterone and phenytoin reduce neuronal nitric oxide synthase messenger RNA expression in rat hippocampus
    • Reagan LP, McKittrick CR, McEwen BS (1999) Corticosterone and phenytoin reduce neuronal nitric oxide synthase messenger RNA expression in rat hippocampus. Neuroscience 91:211-219.
    • (1999) Neuroscience , vol.91 , pp. 211-219
    • Reagan, L.P.1    McKittrick, C.R.2    McEwen, B.S.3
  • 32
    • 0022399686 scopus 로고
    • Glucocorticoid toxicity in the hippocampus: Temporal aspects of neuronal vulnerability
    • Sapolsky RM (1985) Glucocorticoid toxicity in the hippocampus: temporal aspects of neuronal vulnerability. Brain Res 359:300-305.
    • (1985) Brain Res , vol.359 , pp. 300-305
    • Sapolsky, R.M.1
  • 33
    • 17844375406 scopus 로고    scopus 로고
    • The influence of social hierarchy on primate health
    • Sapolsky RM (2005) The influence of social hierarchy on primate health. Science 308:648-652.
    • (2005) Science , vol.308 , pp. 648-652
    • Sapolsky, R.M.1
  • 34
    • 0022345349 scopus 로고
    • Glucocorticoids potentiate ischemic injury to neurons: Therapeutic implications
    • Sapolsky RM, Pulsinelli WA (1985) Glucocorticoids potentiate ischemic injury to neurons: therapeutic implications. Science 229:1397-1399.
    • (1985) Science , vol.229 , pp. 1397-1399
    • Sapolsky, R.M.1    Pulsinelli, W.A.2
  • 35
    • 0023946137 scopus 로고
    • Glucocorticoid toxicity in the hippocampus: In vitro demonstration
    • Sapolsky RM, Packan DR, Vale WW (1988) Glucocorticoid toxicity in the hippocampus: in vitro demonstration. Brain Res 453:367-371.
    • (1988) Brain Res , vol.453 , pp. 367-371
    • Sapolsky, R.M.1    Packan, D.R.2    Vale, W.W.3
  • 36
    • 0003638683 scopus 로고
    • revised edition. New York: McGraw-Hill
    • Seyle H (1984) The stress of life, revised edition. New York: McGraw-Hill.
    • (1984) The stress of life
    • Seyle, H.1
  • 37
    • 0028131169 scopus 로고
    • Stress exacerbates neuron loss and cytoskeletal pathology in the hippocampus
    • Stein-Behrens B, Mattson MP, Chang I, Yeh M, Sapolsky R (1994) Stress exacerbates neuron loss and cytoskeletal pathology in the hippocampus. J Neurosci 14:5373-5380.
    • (1994) J Neurosci , vol.14 , pp. 5373-5380
    • Stein-Behrens, B.1    Mattson, M.P.2    Chang, I.3    Yeh, M.4    Sapolsky, R.5
  • 38
    • 0024409623 scopus 로고
    • Hippocampal damage associated with prolonged and fatal stress in primates
    • Uno H, Tarara R, Else JG, Suleman MA, Sapolsky RM (1989) Hippocampal damage associated with prolonged and fatal stress in primates. J Neurosci 9:1705-1711.
    • (1989) J Neurosci , vol.9 , pp. 1705-1711
    • Uno, H.1    Tarara, R.2    Else, J.G.3    Suleman, M.A.4    Sapolsky, R.M.5
  • 39
    • 0026781307 scopus 로고
    • Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons
    • Watanabe Y, Gould E, McEwen BS (1992a) Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. Brain Res 588:341-345.
    • (1992) Brain Res , vol.588 , pp. 341-345
    • Watanabe, Y.1    Gould, E.2    McEwen, B.S.3
  • 40
    • 0026939448 scopus 로고
    • Phenytoin prevents stress- and corticosterone-induced atrophy of CA3 pyramidal neurons
    • Watanabe Y, Gould E, Cameron HA, Daniels DC, McEwen BS (1992b) Phenytoin prevents stress- and corticosterone-induced atrophy of CA3 pyramidal neurons. Hippocampus 2:431-436.
    • (1992) Hippocampus , vol.2 , pp. 431-436
    • Watanabe, Y.1    Gould, E.2    Cameron, H.A.3    Daniels, D.C.4    McEwen, B.S.5
  • 41
    • 0025168942 scopus 로고
    • Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons
    • Woolley CS, Gould E, McEwen BS (1990) Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons. Brain Res 531:225-231.
    • (1990) Brain Res , vol.531 , pp. 225-231
    • Woolley, C.S.1    Gould, E.2    McEwen, B.S.3
  • 42
    • 33746210780 scopus 로고    scopus 로고
    • Attenuating corticosterone levels on the day of memory assessment prevents chronic stress-induced impairments in spatial memory
    • Wright RL, Lightner EN, Harman JS, Meijer OC, Conrad CD (2006) Attenuating corticosterone levels on the day of memory assessment prevents chronic stress-induced impairments in spatial memory. Eur J Neurosci 24:595-605.
    • (2006) Eur J Neurosci , vol.24 , pp. 595-605
    • Wright, R.L.1    Lightner, E.N.2    Harman, J.S.3    Meijer, O.C.4    Conrad, C.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.