메뉴 건너뛰기




Volumn 217, Issue 4, 2010, Pages 324-333

When cortical development goes wrong: Schizophrenia as a neurodevelopmental disease of microcircuits

Author keywords

Cortex; Dendritic spines; Glutamatergic neurons; Microglia; Neurodevelopment; Post mortem; Schizophrenia

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; HLA DR ANTIGEN; KAINIC ACID RECEPTOR;

EID: 77956466815     PISSN: 00218782     EISSN: 14697580     Source Type: Journal    
DOI: 10.1111/j.1469-7580.2010.01231.x     Document Type: Article
Times cited : (132)

References (85)
  • 1
    • 0027394523 scopus 로고
    • Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development
    • Akbarian S, Bunney WE, Potkin SG. Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development. Arch Gen Psychiatry 1993, 50:169-177.
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 169-177
    • Akbarian, S.1    Bunney, W.E.2    Potkin, S.G.3
  • 2
    • 77956493486 scopus 로고    scopus 로고
    • The dynamics of excitatory synapse formation on dendritic spines
    • Amaral MD, Pozzo-Miller L. The dynamics of excitatory synapse formation on dendritic spines. Cellscience 2009, 5:19-25.
    • (2009) Cellscience , vol.5 , pp. 19-25
    • Amaral, M.D.1    Pozzo-Miller, L.2
  • 3
    • 0020058822 scopus 로고
    • Ventricular enlargement in schizophrenia: definition and prevalence
    • Andreasen NC, Smith MR, Jacoby CG. Ventricular enlargement in schizophrenia: definition and prevalence. Am J Psychiatry 1982, 139:292-296.
    • (1982) Am J Psychiatry , vol.139 , pp. 292-296
    • Andreasen, N.C.1    Smith, M.R.2    Jacoby, C.G.3
  • 4
    • 0022271888 scopus 로고
    • Synaptic rearrangements in medial prefrontal cortex of haloperidol-treated rats
    • Benes FM, Paskevich PA, Davidson J. Synaptic rearrangements in medial prefrontal cortex of haloperidol-treated rats. Brain Res 1985, 348:15-20.
    • (1985) Brain Res , vol.348 , pp. 15-20
    • Benes, F.M.1    Paskevich, P.A.2    Davidson, J.3
  • 5
    • 0000339287 scopus 로고
    • A shift in tyrosine hydroxylase-immunoreactive varicosities (TH-IRv) from pyramidal (PN) to nonpyramidal (NP) neurons occurs in layer II of the anterior cingulate cortex of schizophrenics
    • Benes FM, Todtenkopf MS, Taylor JB. A shift in tyrosine hydroxylase-immunoreactive varicosities (TH-IRv) from pyramidal (PN) to nonpyramidal (NP) neurons occurs in layer II of the anterior cingulate cortex of schizophrenics. Abstr Soc Neurosci 1995, 21:259.
    • (1995) Abstr Soc Neurosci , vol.21 , pp. 259
    • Benes, F.M.1    Todtenkopf, M.S.2    Taylor, J.B.3
  • 6
    • 68549099832 scopus 로고    scopus 로고
    • Positive and negative symptoms in schizophrenia: the NMDA receptor hypofunction hypothesis, neuregulin/ErbB4 and synapse regression
    • Bennett M. Positive and negative symptoms in schizophrenia: the NMDA receptor hypofunction hypothesis, neuregulin/ErbB4 and synapse regression. Aust N Z J Psychiatry 2009, 43:711-721.
    • (2009) Aust N Z J Psychiatry , vol.43 , pp. 711-721
    • Bennett, M.1
  • 7
    • 67651055423 scopus 로고    scopus 로고
    • Glial cells in schizophrenia: pathophysiological significance and possible consequences for therapy
    • Bernstein HG, Steiner J, Bogerts B. Glial cells in schizophrenia: pathophysiological significance and possible consequences for therapy. Expert Rev Neurother 2009, 9:1059-1071.
    • (2009) Expert Rev Neurother , vol.9 , pp. 1059-1071
    • Bernstein, H.G.1    Steiner, J.2    Bogerts, B.3
  • 10
    • 0027440223 scopus 로고
    • Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics
    • Browning MD, Dudek EM, Rapier JL. Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics. Biol Psychiatry 1993, 34:529-535.
    • (1993) Biol Psychiatry , vol.34 , pp. 529-535
    • Browning, M.D.1    Dudek, E.M.2    Rapier, J.L.3
  • 11
    • 0029799516 scopus 로고    scopus 로고
    • Prenatal development of parvalbumin immunoreactivity in the human striate cortex
    • Cao QL, Yan XX, Luo XG. Prenatal development of parvalbumin immunoreactivity in the human striate cortex. Cereb Cortex 1996, 6:620-630.
    • (1996) Cereb Cortex , vol.6 , pp. 620-630
    • Cao, Q.L.1    Yan, X.X.2    Luo, X.G.3
  • 12
    • 0023745722 scopus 로고
    • Decreased numbers of dendritic spines on cortical pyramidal neurons in dementia. A quantitative Golgi study on biopsy samples
    • Catalá I, Ferrer I, Galofré E. Decreased numbers of dendritic spines on cortical pyramidal neurons in dementia. A quantitative Golgi study on biopsy samples. Hum Neurobiol 1988, 6:255-259.
    • (1988) Hum Neurobiol , vol.6 , pp. 255-259
    • Catalá, I.1    Ferrer, I.2    Galofré, E.3
  • 13
    • 77956489610 scopus 로고
    • A comparison of dendritic spine number and type on pyramidal neurons of the visual cortex of old adult rats from social or isolated environments
    • Connor JR, Diamond MC. A comparison of dendritic spine number and type on pyramidal neurons of the visual cortex of old adult rats from social or isolated environments. J Comp Neurol 1982, 2:10.
    • (1982) J Comp Neurol , vol.2 , pp. 10
    • Connor, J.R.1    Diamond, M.C.2
  • 14
    • 0024806580 scopus 로고
    • Schizophrenia as an anomaly of development of cerebral asymmetry. A postmortem study and a proposal concerning the genetic basis of the disease
    • Crow TJ, Ball J, Bloom SR. Schizophrenia as an anomaly of development of cerebral asymmetry. A postmortem study and a proposal concerning the genetic basis of the disease. Arch Gen Psychiatry 1989, 46:1145-1150.
    • (1989) Arch Gen Psychiatry , vol.46 , pp. 1145-1150
    • Crow, T.J.1    Ball, J.2    Bloom, S.R.3
  • 15
    • 0022625487 scopus 로고
    • A family study of the association of increased ventricular size with schizophrenia
    • DeLisi LE, Goldin LR, Hamovit JR. A family study of the association of increased ventricular size with schizophrenia. Arch Gen Psychiatry 1986, 43:148-153.
    • (1986) Arch Gen Psychiatry , vol.43 , pp. 148-153
    • DeLisi, L.E.1    Goldin, L.R.2    Hamovit, J.R.3
  • 16
    • 0027965383 scopus 로고
    • Childhood antecedents of schizophrenia and affective illness: social adjustments at age 7 and 11
    • Done DJ, Crow TJ, Johnstone EC. Childhood antecedents of schizophrenia and affective illness: social adjustments at age 7 and 11. Br Med J 1994, 309:699-703.
    • (1994) Br Med J , vol.309 , pp. 699-703
    • Done, D.J.1    Crow, T.J.2    Johnstone, E.C.3
  • 17
    • 67651158785 scopus 로고    scopus 로고
    • Pyramidal neuron number in layer 3 of primary auditory cortex of subjects with schizophrenia
    • Dorph-Petersen KA, Delevich KM, Marcsisin MJ. Pyramidal neuron number in layer 3 of primary auditory cortex of subjects with schizophrenia. Brain Res 2009, 1285:42-57.
    • (2009) Brain Res , vol.1285 , pp. 42-57
    • Dorph-Petersen, K.A.1    Delevich, K.M.2    Marcsisin, M.J.3
  • 18
    • 0023726688 scopus 로고
    • Limbic pathology in schizophrenia: the entorhinal region - a morphometric study
    • Falkai P, Bogerts B, Rozumek M. Limbic pathology in schizophrenia: the entorhinal region - a morphometric study. Biol Psychiatry 1988, 24:515-521.
    • (1988) Biol Psychiatry , vol.24 , pp. 515-521
    • Falkai, P.1    Bogerts, B.2    Rozumek, M.3
  • 19
    • 0022503055 scopus 로고
    • Decreased numbers of dendritic spines on cortical pyramidal neurons in human chronic alcoholism
    • Ferrer I, Fábregues I, Rairiz J. Decreased numbers of dendritic spines on cortical pyramidal neurons in human chronic alcoholism. Neurosci Lett 1986, 69:115-119.
    • (1986) Neurosci Lett , vol.69 , pp. 115-119
    • Ferrer, I.1    Fábregues, I.2    Rairiz, J.3
  • 20
    • 0021330769 scopus 로고
    • Glutamate: a neurotransmitter in mammalian brain
    • Fonnum F. Glutamate: a neurotransmitter in mammalian brain. J Neurochem 1984, 42:1-11.
    • (1984) J Neurochem , vol.42 , pp. 1-11
    • Fonnum, F.1
  • 21
    • 0029757351 scopus 로고    scopus 로고
    • Imaging as a tool in exploring the neurodevelopment and genetics of schizophrenia
    • Frangou S, Murray RM. Imaging as a tool in exploring the neurodevelopment and genetics of schizophrenia. Brit Med Bull 1996, 52:587-596.
    • (1996) Brit Med Bull , vol.52 , pp. 587-596
    • Frangou, S.1    Murray, R.M.2
  • 22
    • 34548377234 scopus 로고
    • Dendritic spine loss on pyramidal cells of temporal cortex in schizophrenia
    • Garey LJ, Ong WY, Barnes TRE. Dendritic spine loss on pyramidal cells of temporal cortex in schizophrenia. Neuropathol Appl Neurobiol 1993, 19:186-187.
    • (1993) Neuropathol Appl Neurobiol , vol.19 , pp. 186-187
    • Garey, L.J.1    Ong, W.Y.2    Barnes, T.R.E.3
  • 23
    • 0000503059 scopus 로고
    • Reduction in dendritic spine number on cortical pyramidal neurons in schizophrenia
    • Garey LJ, Ong WY, Patel TS. Reduction in dendritic spine number on cortical pyramidal neurons in schizophrenia. Abstr Soc Neurosci 1995, 21:237.
    • (1995) Abstr Soc Neurosci , vol.21 , pp. 237
    • Garey, L.J.1    Ong, W.Y.2    Patel, T.S.3
  • 24
    • 0031758376 scopus 로고    scopus 로고
    • Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia
    • Garey LJ, Ong WY, Patel TS. Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia. J Neurol Neurosurg Psychiatry 1998, 65:446-453.
    • (1998) J Neurol Neurosurg Psychiatry , vol.65 , pp. 446-453
    • Garey, L.J.1    Ong, W.Y.2    Patel, T.S.3
  • 25
    • 33747607524 scopus 로고    scopus 로고
    • Decreased numerical density of kainate receptor-positive neurons in the orbitofrontal cortex of chronic schizophrenics
    • Garey LJ, Von Bussmann KA, Hirsch SR. Decreased numerical density of kainate receptor-positive neurons in the orbitofrontal cortex of chronic schizophrenics. Exp Brain Res 2006, 173:234-242.
    • (2006) Exp Brain Res , vol.173 , pp. 234-242
    • Garey, L.J.1    Von Bussmann, K.A.2    Hirsch, S.R.3
  • 26
    • 0029076362 scopus 로고
    • Microglia: intrinsic immunoeffector cell of the human brain
    • Gehrmann J, Matsumoto Y, Kreutzberg GW. Microglia: intrinsic immunoeffector cell of the human brain. Brain Res Rev 1993, 20:269-287.
    • (1993) Brain Res Rev , vol.20 , pp. 269-287
    • Gehrmann, J.1    Matsumoto, Y.2    Kreutzberg, G.W.3
  • 27
    • 0000507514 scopus 로고
    • Assessment of spine density on layer III pyramidal cells in the prefrontal cortex of schizophrenic subjects
    • Glantz LA, Lewis DA. Assessment of spine density on layer III pyramidal cells in the prefrontal cortex of schizophrenic subjects. Abstr Soc Neurosci 1995, 21:239.
    • (1995) Abstr Soc Neurosci , vol.21 , pp. 239
    • Glantz, L.A.1    Lewis, D.A.2
  • 28
    • 0033985644 scopus 로고    scopus 로고
    • Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
    • Glantz LA, Lewis DA. Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch Gen Psychiatry 2000, 57:65-73.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 65-73
    • Glantz, L.A.1    Lewis, D.A.2
  • 29
    • 0025538287 scopus 로고
    • Loss of dendritic spines in Alzheimer's disease
    • el Hachimi KH, Foncin JF. Loss of dendritic spines in Alzheimer's disease. C R Acad Sci III 1990, 311:387-402.
    • (1990) C R Acad Sci III , vol.311 , pp. 387-402
    • el Hachimi, K.H.1    Foncin, J.F.2
  • 30
    • 36849076332 scopus 로고    scopus 로고
    • Progressive brain volume loss in schizophrenia over the course of the illness: Evidence of maturational abnormalities in early adulthood
    • van Haren NEM, Pol HEH, Schnack HG. Progressive brain volume loss in schizophrenia over the course of the illness: Evidence of maturational abnormalities in early adulthood. Biol Psychiatry 2008, 63:106-113.
    • (2008) Biol Psychiatry , vol.63 , pp. 106-113
    • van Haren, N.E.M.1    Pol, H.E.H.2    Schnack, H.G.3
  • 31
    • 0029079017 scopus 로고
    • On the neuropathology of schizophrenia and its dementia: neurodevelopmental, neurodegenerative, or both?
    • Harrison PJ. On the neuropathology of schizophrenia and its dementia: neurodevelopmental, neurodegenerative, or both? Neurodegen 1995, 4:1-12.
    • (1995) Neurodegen , vol.4 , pp. 1-12
    • Harrison, P.J.1
  • 32
    • 0030951230 scopus 로고    scopus 로고
    • Schizophrenia: a disorder of neuro-development
    • Harrison PJ. Schizophrenia: a disorder of neuro-development. Curr Opin Neurobiol 1997, 7:285-289.
    • (1997) Curr Opin Neurobiol , vol.7 , pp. 285-289
    • Harrison, P.J.1
  • 33
    • 0025967753 scopus 로고
    • Decreased hippocampal expression of a glutamate receptor gene in schizophrenia
    • Harrison PJ, McLaughlin D, Kerwin RW. Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. Lancet 1991, 337:450-452.
    • (1991) Lancet , vol.337 , pp. 450-452
    • Harrison, P.J.1    McLaughlin, D.2    Kerwin, R.W.3
  • 34
    • 0027197758 scopus 로고
    • Reduction of cortical volume in schizophrenia on magnetic resonance imaging
    • Harvey I, Ron MA, Du Boulay G. Reduction of cortical volume in schizophrenia on magnetic resonance imaging. Psychol Med 1993, 23:591-604.
    • (1993) Psychol Med , vol.23 , pp. 591-604
    • Harvey, I.1    Ron, M.A.2    Du Boulay, G.3
  • 35
    • 33745698814 scopus 로고    scopus 로고
    • Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia
    • Hill JJ, Hashimoto T, Lewis DA. Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia. Mol Psychiatry 2006, 11:557-566.
    • (2006) Mol Psychiatry , vol.11 , pp. 557-566
    • Hill, J.J.1    Hashimoto, T.2    Lewis, D.A.3
  • 36
    • 0030966724 scopus 로고    scopus 로고
    • A pivotal role for glutamate in the pathogenesis of schizophrenia, and its cognitive dysfunction
    • Hirsch SR, Das I, Garey LJ. A pivotal role for glutamate in the pathogenesis of schizophrenia, and its cognitive dysfunction. Pharmacol Biochem Behav 1997, 56:797-802.
    • (1997) Pharmacol Biochem Behav , vol.56 , pp. 797-802
    • Hirsch, S.R.1    Das, I.2    Garey, L.J.3
  • 37
    • 38949193560 scopus 로고    scopus 로고
    • Is gray matter volume an intermediate phenotype for schizophrenia? A voxel-based morphometry study of patients with schizophrenia and their healthy siblings
    • Honea RA, Meyer-Lindenberg A, Hobbs KB. Is gray matter volume an intermediate phenotype for schizophrenia? A voxel-based morphometry study of patients with schizophrenia and their healthy siblings. Biol Psychiatry 2008, 63:465-474.
    • (2008) Biol Psychiatry , vol.63 , pp. 465-474
    • Honea, R.A.1    Meyer-Lindenberg, A.2    Hobbs, K.B.3
  • 38
    • 0027324536 scopus 로고
    • Selective distribution of kainate receptor subunit immunoreactivity in monkey neocortex revealed by a monoclonal antibody that recognizes glutamate receptor subunits GluR5/6/7
    • Huntley GW, Rogers SW, Moran T. Selective distribution of kainate receptor subunit immunoreactivity in monkey neocortex revealed by a monoclonal antibody that recognizes glutamate receptor subunits GluR5/6/7. J Neurosci 1993, 13:2965-2981.
    • (1993) J Neurosci , vol.13 , pp. 2965-2981
    • Huntley, G.W.1    Rogers, S.W.2    Moran, T.3
  • 39
    • 0018376668 scopus 로고
    • Synaptic density in human frontal cortex: developmental changes and effects of aging
    • Huttenlocher PR. Synaptic density in human frontal cortex: developmental changes and effects of aging. Brain Res 1979, 163:195-205.
    • (1979) Brain Res , vol.163 , pp. 195-205
    • Huttenlocher, P.R.1
  • 40
    • 0021337105 scopus 로고
    • Synapse elimination and plasticity in developing human cerebral cortex
    • Huttenlocher PR. Synapse elimination and plasticity in developing human cerebral cortex. Am J Ment Defic 1984, 88:488-496.
    • (1984) Am J Ment Defic , vol.88 , pp. 488-496
    • Huttenlocher, P.R.1
  • 41
    • 0030883534 scopus 로고    scopus 로고
    • Regional differences in synaptogenesis in human cerebral cortex
    • Huttenlocher PR, Dabholkar AS. Regional differences in synaptogenesis in human cerebral cortex. J Comp Neurol 1997, 387:167-178.
    • (1997) J Comp Neurol , vol.387 , pp. 167-178
    • Huttenlocher, P.R.1    Dabholkar, A.S.2
  • 42
    • 0020262681 scopus 로고
    • Synaptogenesis in human visual cortex - evidence for synapse elimination during normal development
    • Huttenlocher PR, de Courten C, Garey LJ. Synaptogenesis in human visual cortex - evidence for synapse elimination during normal development. Neurosci Lett 1982, 33:247-252.
    • (1982) Neurosci Lett , vol.33 , pp. 247-252
    • Huttenlocher, P.R.1    de Courten, C.2    Garey, L.J.3
  • 43
    • 0030759136 scopus 로고    scopus 로고
    • Life-span dendritic and spine changes in areas 10 and 18 of human cortex: a quantitative Golgi study
    • Jacobs B, Driscoll L, Schall M. Life-span dendritic and spine changes in areas 10 and 18 of human cortex: a quantitative Golgi study. J Comp Neurol 1997, 386:661-680.
    • (1997) J Comp Neurol , vol.386 , pp. 661-680
    • Jacobs, B.1    Driscoll, L.2    Schall, M.3
  • 44
    • 84921009118 scopus 로고
    • Cerebral ventricular size and cognitive impairment in chronic schizophrenia
    • Johnstone EC, Crow TJ, Frith CD. Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet 1976, ii:924-926.
    • (1976) Lancet , vol.2 , pp. 924-926
    • Johnstone, E.C.1    Crow, T.J.2    Frith, C.D.3
  • 45
    • 0028308126 scopus 로고
    • Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited
    • Keshavan MS, Anderson S, Pettegrew JW. Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited. J Psychiatr Res 1994, 28:239-265.
    • (1994) J Psychiatr Res , vol.28 , pp. 239-265
    • Keshavan, M.S.1    Anderson, S.2    Pettegrew, J.W.3
  • 46
    • 0019293020 scopus 로고
    • Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia
    • Kim JS, Kornhuber HH, Schmid-Burgk W. Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia. Neurosci Lett 1980, 20:379-382.
    • (1980) Neurosci Lett , vol.20 , pp. 379-382
    • Kim, J.S.1    Kornhuber, H.H.2    Schmid-Burgk, W.3
  • 47
    • 20044380772 scopus 로고    scopus 로고
    • Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia
    • Kolluri N, Sun Z, Sampson AR. Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia. Am J Psychiatry 2005, 162:1200-1202.
    • (2005) Am J Psychiatry , vol.162 , pp. 1200-1202
    • Kolluri, N.1    Sun, Z.2    Sampson, A.R.3
  • 48
    • 33747605486 scopus 로고    scopus 로고
    • A positional analysis of a subset of cortical neurons in the frontal cortex of schizophrenic brains
    • Leclercq P, Royston MC, Garey LJ. A positional analysis of a subset of cortical neurons in the frontal cortex of schizophrenic brains. Neuropathol Appl Neurobiol 1996, 22:164.
    • (1996) Neuropathol Appl Neurobiol , vol.22 , pp. 164
    • Leclercq, P.1    Royston, M.C.2    Garey, L.J.3
  • 49
    • 77956495004 scopus 로고    scopus 로고
    • An automated position analysis of parvalbumin-immunoreactive cells in the cerebral cortex in control and schizophrenic post-mortem brain
    • Leclerq PD, Garey LJ, Gentleman SM. An automated position analysis of parvalbumin-immunoreactive cells in the cerebral cortex in control and schizophrenic post-mortem brain. Schizophr Res 1998, 29:91.
    • (1998) Schizophr Res , vol.29 , pp. 91
    • Leclerq, P.D.1    Garey, L.J.2    Gentleman, S.M.3
  • 50
    • 0026601337 scopus 로고
    • Patterns of cerebral blood flow in schizophrenia
    • Liddle PF, Friston KJ, Frith CD. Patterns of cerebral blood flow in schizophrenia. Br J Psychiatry 1992, 160:179-186.
    • (1992) Br J Psychiatry , vol.160 , pp. 179-186
    • Liddle, P.F.1    Friston, K.J.2    Frith, C.D.3
  • 52
    • 0016774583 scopus 로고
    • The origin of efferent pathways from the primary visual cortex, area 17, of the macaque monkey as shown by retrograde transport of horseradish peroxidase
    • Lund JS, Lund RD, Hendrickson AE. The origin of efferent pathways from the primary visual cortex, area 17, of the macaque monkey as shown by retrograde transport of horseradish peroxidase. J Comp Neurol 1975, 164:287-303.
    • (1975) J Comp Neurol , vol.164 , pp. 287-303
    • Lund, J.S.1    Lund, R.D.2    Hendrickson, A.E.3
  • 53
    • 0016422554 scopus 로고
    • Quantitative study on dendrites and dendritic spines in Alzheimer's disease and senile dementia
    • Mehraein P, Yamada M, Tarnowska-Dziduszco E. Quantitative study on dendrites and dendritic spines in Alzheimer's disease and senile dementia. Adv Neurol 1975, 12:453-458.
    • (1975) Adv Neurol , vol.12 , pp. 453-458
    • Mehraein, P.1    Yamada, M.2    Tarnowska-Dziduszco, E.3
  • 54
    • 0021647667 scopus 로고
    • The development of dendritic spines in the human visual cortex
    • Michel AE, Garey LJ. The development of dendritic spines in the human visual cortex. Hum Neurobiol 1984, 3:223-227.
    • (1984) Hum Neurobiol , vol.3 , pp. 223-227
    • Michel, A.E.1    Garey, L.J.2
  • 55
    • 0025908356 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra SS, Heyman A, McKeel D. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991, 41:479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3
  • 56
    • 0026572073 scopus 로고
    • Prenatal development of neurons in the human prefrontal cortex. II. A quantitative Golgi study
    • Mrzljak L, Uylings HB, Kostovic I. Prenatal development of neurons in the human prefrontal cortex. II. A quantitative Golgi study. J Comp Neurol 1992, 316:485-496.
    • (1992) J Comp Neurol , vol.316 , pp. 485-496
    • Mrzljak, L.1    Uylings, H.B.2    Kostovic, I.3
  • 57
    • 0030623789 scopus 로고    scopus 로고
    • Microwave antigen retrieval in formaldehyde-fixed human brain tissue
    • Newman SJ, Gentleman SM. Microwave antigen retrieval in formaldehyde-fixed human brain tissue. Methods Mol Biol 1997, 72:145-152.
    • (1997) Methods Mol Biol , vol.72 , pp. 145-152
    • Newman, S.J.1    Gentleman, S.M.2
  • 58
    • 0027249541 scopus 로고
    • Ultrastructural features of biopsied temporopolar cortex (area 38) in a case of schizophrenia
    • Ong WY, Garey LJ. Ultrastructural features of biopsied temporopolar cortex (area 38) in a case of schizophrenia. Schizophr Res 1993, 10:15-27.
    • (1993) Schizophr Res , vol.10 , pp. 15-27
    • Ong, W.Y.1    Garey, L.J.2
  • 59
    • 0028087773 scopus 로고
    • The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1
    • Petralia RS, Wang YX, Wenthold RJ. The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J Neurosci 1994, 14:6102-6120.
    • (1994) J Neurosci , vol.14 , pp. 6102-6120
    • Petralia, R.S.1    Wang, Y.X.2    Wenthold, R.J.3
  • 60
    • 0023927742 scopus 로고
    • Computed tomographic evidence for generalized sulcal and ventricular enlargement in schizophrenia
    • Pfefferbaum A, Zipursky RB, Lim KO. Computed tomographic evidence for generalized sulcal and ventricular enlargement in schizophrenia. Arch Gen Psychiatry 1988, 45:633-640.
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 633-640
    • Pfefferbaum, A.1    Zipursky, R.B.2    Lim, K.O.3
  • 61
    • 0027494075 scopus 로고
    • Alzheimer-type neuropathology in elderly schizophrenia patients
    • Prohovnik I, Dwork AJ, Kaufman MA. Alzheimer-type neuropathology in elderly schizophrenia patients. Schizophr Bull 1993, 19:805-816.
    • (1993) Schizophr Bull , vol.19 , pp. 805-816
    • Prohovnik, I.1    Dwork, A.J.2    Kaufman, M.A.3
  • 62
    • 0033983020 scopus 로고    scopus 로고
    • Increase in HLA-DR immunoreactive microglia in frontal and temporal cortex of chronic schizophrenics
    • Radewicz K, Garey LJ, Gentleman SM. Increase in HLA-DR immunoreactive microglia in frontal and temporal cortex of chronic schizophrenics. J Neuropathol Exp Neurol 2000, 59:137-150.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 137-150
    • Radewicz, K.1    Garey, L.J.2    Gentleman, S.M.3
  • 63
    • 0031943325 scopus 로고    scopus 로고
    • Schizophrenia as a developmental disorder of the cerebral cortex
    • Raedler TJ, Knable MB, Weinberger DR. Schizophrenia as a developmental disorder of the cerebral cortex. Curr Opin Neurobiol 1998, 8:157-161.
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 157-161
    • Raedler, T.J.1    Knable, M.B.2    Weinberger, D.R.3
  • 64
    • 0028114577 scopus 로고
    • Synaptic development of the cerebral cortex: implications for learning, memory, and mental illness
    • Rakic P, Bourgeois JP, Goldman-Rakic PS. Synaptic development of the cerebral cortex: implications for learning, memory, and mental illness. Prog Brain Res 1994, 102:227-243.
    • (1994) Prog Brain Res , vol.102 , pp. 227-243
    • Rakic, P.1    Bourgeois, J.P.2    Goldman-Rakic, P.S.3
  • 65
    • 0020073394 scopus 로고
    • Cerebral ventricular size in twins discordant for schizophrenia
    • Reveley AM, Reveley MA, Clifford CA. Cerebral ventricular size in twins discordant for schizophrenia. Lancet 1982, 1:540-541.
    • (1982) Lancet , vol.1 , pp. 540-541
    • Reveley, A.M.1    Reveley, M.A.2    Clifford, C.A.3
  • 66
    • 0029876529 scopus 로고    scopus 로고
    • Schizophrenia, the heteromodal association cortex and development: potential for a neurogenetic approach
    • Ross CA, Pearlson GD. Schizophrenia, the heteromodal association cortex and development: potential for a neurogenetic approach. Trends Neurosci 1996, 19:171-176.
    • (1996) Trends Neurosci , vol.19 , pp. 171-176
    • Ross, C.A.1    Pearlson, G.D.2
  • 67
    • 0016704344 scopus 로고
    • Progressive dendritic changes in aging human cortex
    • Scheibel ME, Lindsay RD, Tomiyasu U. Progressive dendritic changes in aging human cortex. Exp Neurol 1975, 47:392-403.
    • (1975) Exp Neurol , vol.47 , pp. 392-403
    • Scheibel, M.E.1    Lindsay, R.D.2    Tomiyasu, U.3
  • 68
    • 0032967531 scopus 로고    scopus 로고
    • The reduced neuropil hypothesis: a circuit based model of schizophrenia
    • Selemon LD, Goldman-Rakic PS. The reduced neuropil hypothesis: a circuit based model of schizophrenia. Biol Psychiatry 1999, 45:17-25.
    • (1999) Biol Psychiatry , vol.45 , pp. 17-25
    • Selemon, L.D.1    Goldman-Rakic, P.S.2
  • 69
    • 0028825345 scopus 로고
    • Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17
    • Selemon LD, Rajkowska G, Goldman-Rakic PS. Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17. Arch Gen Psychiatry 1995, 52:805-818.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 805-818
    • Selemon, L.D.1    Rajkowska, G.2    Goldman-Rakic, P.S.3
  • 70
    • 0026770030 scopus 로고
    • Light and electron microscopic characterization of dopamine-immunoreactive axons in human cerebral cortex
    • Smiley JF, Williams SM, Szigeti K. Light and electron microscopic characterization of dopamine-immunoreactive axons in human cerebral cortex. J Comp Neurol 1992, 321:325-335.
    • (1992) J Comp Neurol , vol.321 , pp. 325-335
    • Smiley, J.F.1    Williams, S.M.2    Szigeti, K.3
  • 71
    • 0014845857 scopus 로고
    • Langzeitbehandlung mit Chlorpromazin im Tierexperiment
    • Sommer H, Quandt J. Langzeitbehandlung mit Chlorpromazin im Tierexperiment. Fortschr Neurol Psychiatr 1970, 38:466-491.
    • (1970) Fortschr Neurol Psychiatr , vol.38 , pp. 466-491
    • Sommer, H.1    Quandt, J.2
  • 73
    • 0030433695 scopus 로고    scopus 로고
    • The role of microglia in brain injury
    • Streit WJ. The role of microglia in brain injury. Neurotoxicology 1996, 17:671-678.
    • (1996) Neurotoxicology , vol.17 , pp. 671-678
    • Streit, W.J.1
  • 74
    • 0024560598 scopus 로고
    • Temporal lobe pathology in schizophrenia: a quantitative magnetic resonance imaging study
    • Suddath RL, Casanova MF, Goldberg TE. Temporal lobe pathology in schizophrenia: a quantitative magnetic resonance imaging study. Am J Psychiatry 1989, 146:464-472.
    • (1989) Am J Psychiatry , vol.146 , pp. 464-472
    • Suddath, R.L.1    Casanova, M.F.2    Goldberg, T.E.3
  • 75
    • 57849160321 scopus 로고    scopus 로고
    • Reduced dendritic spine density in auditory cortex of subjects with schizophrenia
    • Sweet RA, Henteleff RA, Zhang W. Reduced dendritic spine density in auditory cortex of subjects with schizophrenia. Neuropsychopharm 2009, 34:374-389.
    • (2009) Neuropsychopharm , vol.34 , pp. 374-389
    • Sweet, R.A.1    Henteleff, R.A.2    Zhang, W.3
  • 76
    • 0025863122 scopus 로고
    • Morphometric study of synaptic patterns in the rat caudate nucleus and hippocampus under haloperidol treatment
    • Uranova NA, Orlovskaya DD, Apel K. Morphometric study of synaptic patterns in the rat caudate nucleus and hippocampus under haloperidol treatment. Synapse 1991, 7:253-259.
    • (1991) Synapse , vol.7 , pp. 253-259
    • Uranova, N.A.1    Orlovskaya, D.D.2    Apel, K.3
  • 77
    • 0342510539 scopus 로고
    • Interaction of phencyclidine ('angel dust') with a specific receptor in rat brain membranes
    • Vincent JP, Kartalovski B, Geneste P. Interaction of phencyclidine ('angel dust') with a specific receptor in rat brain membranes. Proc Natl Acad Sci U S A 1979, 76:4678-4682.
    • (1979) Proc Natl Acad Sci U S A , vol.76 , pp. 4678-4682
    • Vincent, J.P.1    Kartalovski, B.2    Geneste, P.3
  • 78
    • 0342375111 scopus 로고    scopus 로고
    • Decreased glutamate binding sites in the left orbitofrontal cortex of chronic schizophrenics
    • Von Bussmann KA, Rodway A, Gentleman SM. Decreased glutamate binding sites in the left orbitofrontal cortex of chronic schizophrenics. Schizophr Res 1996, 18:175.
    • (1996) Schizophr Res , vol.18 , pp. 175
    • Von Bussmann, K.A.1    Rodway, A.2    Gentleman, S.M.3
  • 79
    • 2942641042 scopus 로고    scopus 로고
    • Schizophrenia as a neurodevelopmental disorder
    • Hirsch SR, Weinberger DR. 2nd edn, eds, Hoboken, NJ, Wiley-Blackwell
    • Weinberger DR, Marenco S. Schizophrenia as a neurodevelopmental disorder. Schizophrenia 2003, 326-348. Hirsch SR, Weinberger DR. 2nd edn, eds, Hoboken, NJ, Wiley-Blackwell
    • (2003) Schizophrenia , pp. 326-348
    • Weinberger, D.R.1    Marenco, S.2
  • 81
    • 22144498857 scopus 로고    scopus 로고
    • Quantitative analysis of activated microglia, ramified and damage of processes in the frontal and temporal lobes of chronic schizophrenics
    • Wierzba-Bobrowicz T, Lewandowska E, Lechowicz W. Quantitative analysis of activated microglia, ramified and damage of processes in the frontal and temporal lobes of chronic schizophrenics. Folia Neuropathol 2005, 43:81-89.
    • (2005) Folia Neuropathol , vol.43 , pp. 81-89
    • Wierzba-Bobrowicz, T.1    Lewandowska, E.2    Lechowicz, W.3
  • 82
    • 0029845921 scopus 로고    scopus 로고
    • Prenatal development of NADPH-diaphorase-reactive neurons in human frontal cortex
    • Yan XX, Garey LJ, Jen LS. Prenatal development of NADPH-diaphorase-reactive neurons in human frontal cortex. Cereb Cortex 1996, 6:737-745.
    • (1996) Cereb Cortex , vol.6 , pp. 737-745
    • Yan, X.X.1    Garey, L.J.2    Jen, L.S.3
  • 83
    • 0031043743 scopus 로고    scopus 로고
    • Prenatal development of calbindin D-28K in human visual cortex
    • Yan XX, Cao QL, Luo XG. Prenatal development of calbindin D-28K in human visual cortex. Cereb Cortex 1997, 7:57-62.
    • (1997) Cereb Cortex , vol.7 , pp. 57-62
    • Yan, X.X.1    Cao, Q.L.2    Luo, X.G.3
  • 84
    • 0026590077 scopus 로고
    • Widespread cerebral gray matter volume deficits in schizophrenia
    • Zipursky RB, Lim KO, Sullivan EV. Widespread cerebral gray matter volume deficits in schizophrenia. Arch Gen Psychiatry 1992, 49:195-205.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 195-205
    • Zipursky, R.B.1    Lim, K.O.2    Sullivan, E.V.3
  • 85
    • 0018717463 scopus 로고
    • Specific [3H]phencyclidine binding in rat central nervous system
    • Zukin SR, Zukin RS. Specific [3H]phencyclidine binding in rat central nervous system. Proc Natl Acad Sci U S A 1979, 76:5372-5376.
    • (1979) Proc Natl Acad Sci U S A , vol.76 , pp. 5372-5376
    • Zukin, S.R.1    Zukin, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.