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Volumn 54, Issue 10, 1997, Pages 943-952

Reduction of synaptophysin immunoreactivity in the prefrontal cortex of subjects with schizophrenia regional and diagnostic specificity

Author keywords

[No Author keywords available]

Indexed keywords

SYNAPTOPHYSIN;

EID: 0031254167     PISSN: 0003990X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpsyc.1997.01830220065010     Document Type: Article
Times cited : (213)

References (59)
  • 1
    • 0021352496 scopus 로고
    • Frontal lobe dysfunctions in schizophrenia, II: Impairments of psychological and brain functions
    • Levin S. Frontal lobe dysfunctions in schizophrenia, II: impairments of psychological and brain functions. JPsychiat Res. 1984;18:57-72.
    • (1984) JPsychiat Res. , vol.18 , pp. 57-72
    • Levin, S.1
  • 2
    • 0026447204 scopus 로고
    • Regional cerebral blood flow in monozygotic twins discordant and concordant for schizophrenia
    • Berman KF, Torrey EF, Daniel DG, Weinberger DR. Regional cerebral blood flow in monozygotic twins discordant and concordant for schizophrenia. Arch Gen Psychiatry. 1992;49:927-934.
    • (1992) Arch Gen Psychiatry. , vol.49 , pp. 927-934
    • Berman, K.F.1    Torrey, E.F.2    Daniel, D.G.3    Weinberger, D.R.4
  • 4
    • 0016162693 scopus 로고
    • Abnormalities of cerebral blood flow distribution in patients with chronic schizophrenia
    • Ingvar DH, Franzen G. Abnormalities of cerebral blood flow distribution in patients with chronic schizophrenia. Acta Psychiat Scand. 1974;50:425-462.
    • (1974) Acta Psychiat Scand. , vol.50 , pp. 425-462
    • Ingvar, D.H.1    Franzen, G.2
  • 5
    • 0026485577 scopus 로고
    • Schizophrenics show spatial working memory deficits
    • Park S, Holzman PS. Schizophrenics show spatial working memory deficits. Arch Gen Psychiatry. 1992;49:975-982.
    • (1992) Arch Gen Psychiatry. , vol.49 , pp. 975-982
    • Park, S.1    Holzman, P.S.2
  • 8
    • 0022581021 scopus 로고
    • Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia, I: Regional cerebral blood flow evidence
    • Weinberger DR, Berman KF, Zee RF. Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia, I: regional cerebral blood flow evidence. Arch Gen firyctetry. 1986;43:114-124.
    • (1986) Arch Gen Firyctetry. , vol.43 , pp. 114-124
    • Weinberger, D.R.1    Berman, K.F.2    Zee, R.F.3
  • 10
    • 0026488594 scopus 로고
    • Brain morphology and schizophrenia: A magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures
    • Breier A, Buchanan RW, Elkashef A, Munson RC, Kirkpatrick B, Gellad F. Brain morphology and schizophrenia: a magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures. Arch Gen Psychiatry. 1992:49:921 -926.
    • (1992) Arch Gen Psychiatry. , vol.49 , pp. 921-926
    • Breier, A.1    Buchanan, R.W.2    Elkashef, A.3    Munson, R.C.4    Kirkpatrick, B.5    Gellad, F.6
  • 16
    • 0023521005 scopus 로고
    • Post-mortem study of chronic schizophrenic brains
    • Pakkenberg B. Post-mortem study of chronic schizophrenic brains. BrJPsy:Chiatry. 1987;151:744-752.
    • (1987) BrJPsy:Chiatry. , vol.151 , pp. 744-752
    • Pakkenberg, B.1
  • 17
    • 0027434132 scopus 로고
    • Total nerve cell number in neocortex in chronic schizophrenics and controls estimated using optical disectors
    • Pakkenberg B. Total nerve cell number in neocortex in chronic schizophrenics and controls estimated using optical disectors. Biol Psychiatry. 1993;34:768-772.
    • (1993) Biol Psychiatry. , vol.34 , pp. 768-772
    • Pakkenberg, B.1
  • 18
    • 0028825345 scopus 로고
    • Abnormally high neuronal density in the schizophrenic cortex: A morphometric analysis of prefrontal area 9 and occipital area 17
    • Selemon LD, Rajkowska G, Goldman-Rakic PS. Abnormally high neuronal density in the schizophrenic cortex: a morphometric analysis of prefrontal area 9 and occipital area 17. Arch Gen Psychiatry. 1995:52:805-818.
    • (1995) Arch Gen Psychiatry. , vol.52 , pp. 805-818
    • Selemon, L.D.1    Rajkowska, G.2    Goldman-Rakic, P.S.3
  • 19
    • 0022616146 scopus 로고
    • Quantitative cytoarchitectural studies of the cerebral cortex of schizophrenics
    • Benes FM, Davidson J, Bird ED. Quantitative cytoarchitectural studies of the cerebral cortex of schizophrenics. Arch Gen Psychiatry. 1986;43:31-35.
    • (1986) Arch Gen Psychiatry. , vol.43 , pp. 31-35
    • Benes, F.M.1    Davidson, J.2    Bird, E.D.3
  • 20
    • 0025786847 scopus 로고
    • Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients
    • Benes FM, McSparren J, Bird ED, SanGiovanni JP, Vincent SL. Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients. Arch Gen Psychiatry. 1991 ;48:996-1001.
    • (1991) Arch Gen Psychiatry. , vol.48 , pp. 996-1001
    • Benes, F.M.1    McSparren, J.2    Bird, E.D.3    Sangiovanni, J.P.4    Vincent, S.L.5
  • 23
    • 0023032310 scopus 로고
    • Protein p38: An integral membrane protein specific for small vesicles of neurons and neuroendocrine cells
    • Navone F, Jahn R, DiGioia G, Stukenbrok H, Greengard P, DeCamilli P. Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells. J Cell Biol. 1986;103:2511 -2527.
    • (1986) J Cell Biol. , vol.103 , pp. 2511-2527
    • Navone, F.1    Jahn, R.2    Digioia, G.3    Stukenbrok, H.4    Greengard, P.5    Decamilli, P.6
  • 24
    • 0022391791 scopus 로고
    • Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles
    • Wiedenmann B, Franke WW. Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles. Cell. 1985:41:1017-1028.
    • (1985) Cell. , vol.41 , pp. 1017-1028
    • Wiedenmann, B.1    Franke, W.W.2
  • 25
    • 0026757008 scopus 로고
    • Calcium-dependent transmitter secretion reconstituted in Xenopusoocyles: Requirement for synaptophysin
    • Alder J, Lu B, Valtorta F, Greengard P, Poo M. Calcium-dependent transmitter secretion reconstituted in Xenopusoocyles: requirement for synaptophysin. Science. 1992:257:657-661.
    • (1992) Science. , vol.257 , pp. 657-661
    • Alder, J.1    Lu, B.2    Valtorta, F.3    Greengard, P.4    Poo, M.5
  • 26
    • 0028800496 scopus 로고
    • Overexpression of synaptophysin enhances neurotransmitter secretion at xenopus neuromuscular synapses
    • Alder J, Kanki H, Valtorta F, Greengard P, Poo M. Overexpression of synaptophysin enhances neurotransmitter secretion at xenopus neuromuscular synapses. JNeurosci. 1995:15:511-519.
    • (1995) JNeurosci. , vol.15 , pp. 511-519
    • Alder, J.1    Kanki, H.2    Valtorta, F.3    Greengard, P.4    Poo, M.5
  • 27
    • 0024595972 scopus 로고
    • Synaptic loss in Alzheimer's disease and other dementias
    • Hamos JE, DeGennaro LJ, Drachman DA. Synaptic loss in Alzheimer's disease and other dementias. Neurology. 1989:39:355-361.
    • (1989) Neurology. , vol.39 , pp. 355-361
    • Hamos, J.E.1    Degennaro, L.J.2    Drachman, D.A.3
  • 28
    • 0025330775 scopus 로고
    • Quantitative immunohistochemistry of synaptophysin in human neocortex: An alternative method to estimate density of presynaptic terminals in paraffin sections
    • Masliah E, Terry RD, Alford M, DeTeresa R. Quantitative immunohistochemistry of synaptophysin in human neocortex: an alternative method to estimate density of presynaptic terminals in paraffin sections. JHistochem Cytochem. 1990:38:837-844.
    • (1990) JHistochem Cytochem. , vol.38 , pp. 837-844
    • Masliah, E.1    Terry, R.D.2    Alford, M.3    Deteresa, R.4
  • 29
    • 0026032039 scopus 로고
    • Cortical and subcortical patterns of synaptophysinlike immunoreactivity in Alzheimer's disease
    • Masliah E, Terry RD, Alford M, DeTeresa R, Hansen LA. Cortical and subcortical patterns of synaptophysinlike immunoreactivity in Alzheimer's disease. AmJPathol. 1991:138:235-246.
    • (1991) AmJPathol. , vol.138 , pp. 235-246
    • Masliah, E.1    Terry, R.D.2    Alford, M.3    Deteresa, R.4    Hansen, L.A.5
  • 30
    • 0022414054 scopus 로고
    • Diagnosis of Alzheimer's disease
    • Khachaturian ZS. Diagnosis of Alzheimer's disease. Arch Neurol. 1985;42:1097-1105.
    • (1985) Arch Neurol. , vol.42 , pp. 1097-1105
    • Khachaturian, Z.S.1
  • 31
    • 0026029607 scopus 로고
    • Drug abuse in schizophrenic patients: Clinical correlates and reasons or use
    • Dixon L, Haas G, Weiden PJ. Sweeney J, Frances AJ. Drug abuse in schizophrenic patients: clinical correlates and reasons (or use. Am J Psychiatry. 1991 ;148:224-230.
    • (1991) Am J Psychiatry. , vol.148 , pp. 224-230
    • Dixon, L.1    Haas, G.2    Weiden, P.J.3    Sweeney, J.4    Frances, A.J.5
  • 32
    • 0029559442 scopus 로고
    • Local circuit neurons of the prefrontal cortex in schizophrenia: Selective increase in the density of caibindin-immunoreactive neurons
    • Daviss SR, Lewis DA. Local circuit neurons of the prefrontal cortex in schizophrenia: selective increase in the density of caibindin-immunoreactive neurons. Psychiatry Res. 1995:59:81-96.
    • (1995) Psychiatry Res. , vol.59 , pp. 81-96
    • Daviss, S.R.1    Lewis, D.A.2
  • 33
    • 0029155544 scopus 로고
    • Postnatal maturation of the dopaminergic innervation of monkey prefrontal and motor cortices: A tyrosine hydroxylase immunohistochemical analysis
    • Rosenberg DR, Lewis DA. Postnatal maturation of the dopaminergic innervation of monkey prefrontal and motor cortices: a tyrosine hydroxylase immunohistochemical analysis. J Comp Neurol. 1995:358:383-400.
    • (1995) J Comp Neurol. , vol.358 , pp. 383-400
    • Rosenberg, D.R.1    Lewis, D.A.2
  • 34
    • 0023222380 scopus 로고
    • The laminar and regional distribution of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: A quantitative study of visual and auditory cortices
    • Lewis DA, Campbell MJ, Terry RD, Morrison JH. The laminar and regional distribution of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices. J Neurosci. 1987;7:1799-1808.
    • (1987) J Neurosci. , vol.7 , pp. 1799-1808
    • Lewis, D.A.1    Campbell, M.J.2    Terry, R.D.3    Morrison, J.H.4
  • 35
    • 0029126129 scopus 로고
    • Cytoarchitectonic definition of prefrontal areas in the normal human cortex, I: Remapping of areas 9 and 46 using quantitative criteria
    • Rajkowska G, Goldman-Rakic PS. Cytoarchitectonic definition of prefrontal areas in the normal human cortex, I: remapping of areas 9 and 46 using quantitative criteria. Cereb Cortex. 1995:5:307-322.
    • (1995) Cereb Cortex. , vol.5 , pp. 307-322
    • Rajkowska, G.1    Goldman-Rakic, P.S.2
  • 36
    • 84989104548 scopus 로고
    • SVP38: A synaptic vesicle protein whose appearance correlates closely with synaptogenesis in the rat nervous system
    • Devoto SH, Barnstable CJ. SVP38: a synaptic vesicle protein whose appearance correlates closely with synaptogenesis in the rat nervous system. Ann N YAcad Set. 1987:493:493-496.
    • (1987) Ann N YAcad Set. , vol.493 , pp. 493-496
    • Devoto, S.H.1    Barnstable, C.J.2
  • 37
    • 85012748571 scopus 로고
    • Image analytic techniques for quantification of immunohistochemical staining in the nervous system
    • Conn PM, ed. Orlando, Fla: Academic Press Inc
    • Smolen AJ. Image analytic techniques for quantification of immunohistochemical staining in the nervous system. In: Conn PM, ed. Quantitative and Qualitative Microscopy. Orlando, Fla: Academic Press Inc; 1990:208-229.
    • (1990) Quantitative and Qualitative Microscopy. , pp. 208-229
    • Smolen, A.J.1
  • 38
    • 0030472783 scopus 로고    scopus 로고
    • Levels of the growth-associated protein GAP-43 are selectively increased in association cortices in schizophrenia
    • Perrone-Bizzozero NI, Sower AC, Bird ED, Benowitz LI, Ivins KJ, Neve RL Levels of the growth-associated protein GAP-43 are selectively increased in association cortices in schizophrenia. ProcNatlAcadSciUSA 1996:93:14182-14187.
    • (1996) ProcNatlAcadSciUSA , vol.93 , pp. 14182-14187
    • Perrone-Bizzozero, N.I.1    Sower, A.C.2    Bird, E.D.3    Benowitz, L.I.4    Ivins, K.J.5    Neve, R.L.6
  • 39
    • 0027440223 scopus 로고
    • Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics
    • Browning MD, Dudek EM, Rapier JL, Leonard S, Freedman R. Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics. Biol Psychiatry. 1993:34:529-535.
    • (1993) Biol Psychiatry. , vol.34 , pp. 529-535
    • Browning, M.D.1    Dudek, E.M.2    Rapier, J.L.3    Leonard, S.4    Freedman, R.5
  • 40
    • 0028853825 scopus 로고
    • Decreased synaptophysin in the medial temporal lobe in schizophrenia demonstrated using immunoautoradiography
    • Eastwood SL, Harrison PJ. Decreased synaptophysin in the medial temporal lobe in schizophrenia demonstrated using immunoautoradiography. Neuroscience. 1995:69:339-343.
    • (1995) Neuroscience. , vol.69 , pp. 339-343
    • Eastwood, S.L.1    Harrison, P.J.2
  • 41
    • 0025759879 scopus 로고
    • Quantitative image analysis with densitometry for immunohistochemistry and autoradiography of receptor binding sites-methodological considerations
    • Peretti-Renucci R, Feuerstein C, Manier M, Lorimier P, Savasta M, Thibault J, Mons N, Geffard M. Quantitative image analysis with densitometry for immunohistochemistry and autoradiography of receptor binding sites-methodological considerations. J Neurosei Res. 1991;28:583-600.
    • (1991) J Neurosei Res. , vol.28 , pp. 583-600
    • Peretti-Renucci, R.1    Feuerstein, C.2    Manier, M.3    Lorimier, P.4    Savasta, M.5    Thibault, J.6    Mons, N.7    Geffard, M.8
  • 43
    • 0025788356 scopus 로고
    • Evidence for ultrastructural changes in cortical axodendritic synapses following long-term treatment with haloperidol orclozapine
    • Vincent SL, McSparren J, Wang RY, Benes FM. Evidence for ultrastructural changes in cortical axodendritic synapses following long-term treatment with haloperidol orclozapine. Neuropsychopharmaco/ogy. 1991;5:147-155.
    • (1991) Neuropsychopharmaco/ogy. , vol.5 , pp. 147-155
    • Vincent, S.L.1    McSparren, J.2    Wang, R.Y.3    Benes, F.M.4
  • 45
    • 0025769846 scopus 로고
    • Alterations in brain high-energy phosphate and membrane phospholipid metabolism in first-episode, drug-naive schizophrenics: A pilot study of the dorsal prefrontal cortex by in vivo phosphorus 31 nuclear magnetic resonance imaging
    • Pettegrew JW, Keshavan MS, Panchalingam K, Strychor S, Kaplan DB, Tretta MG, Alien M. Alterations in brain high-energy phosphate and membrane phospholipid metabolism in first-episode, drug-naive schizophrenics: a pilot study of the dorsal prefrontal cortex by in vivo phosphorus 31 nuclear magnetic resonance imaging. Arch Gen Psychiatry. 1991 ;48:563-568.
    • (1991) Arch Gen Psychiatry. , vol.48 , pp. 563-568
    • Pettegrew, J.W.1    Keshavan, M.S.2    Panchalingam, K.3    Strychor, S.4    Kaplan, D.B.5    Tretta, M.G.6    Alien, M.7
  • 46
    • 0029054654 scopus 로고
    • An in vivo study of the prefrontal cortex of schizophrenic patients at different stages of illness via phosphorus magnetic resonance spectroscopy
    • Stanley JA, Williamson PC, Drost DJ, Carr TJ, Rylett RJ, Malla A, Thompson RT. An in vivo study of the prefrontal cortex of schizophrenic patients at different stages of illness via phosphorus magnetic resonance spectroscopy. Arch Gen Psychiatry. 1995:52:399-406.
    • (1995) Arch Gen Psychiatry. , vol.52 , pp. 399-406
    • Stanley, J.A.1    Williamson, P.C.2    Drost, D.J.3    Carr, T.J.4    Rylett, R.J.5    Malla, A.6    Thompson, R.T.7
  • 47
    • 0025911775 scopus 로고
    • Localized phosphorous 31 magnetic resonance spectroscopy in chronic schizophrenic patients and normal controls
    • Williamson P, Drost D, Stanley J, CarrT, Morrison S, Merskey H. Localized phosphorous 31 magnetic resonance spectroscopy in chronic schizophrenic patients and normal controls. Arch Gen Psychiatry. 1991;48:578.
    • (1991) Arch Gen Psychiatry. , vol.48 , pp. 578
    • Williamson, P.1    Drost, D.2    Stanley, J.3    CarrT4    Morrison, S.5    Merskey, H.6
  • 48
    • 0000507514 scopus 로고
    • Assessment of spine density on layer III pyramidal cells in the prefrontal cortex of schizophrenic subjects
    • Glantz LA, Lewis DA. Assessment of spine density on layer III pyramidal cells in the prefrontal cortex of schizophrenic subjects. Soc Neurosci Abstr. 1995;21:239.
    • (1995) Soc Neurosci Abstr. , vol.21 , pp. 239
    • Glantz, L.A.1    Lewis, D.A.2
  • 50
    • 0020390010 scopus 로고
    • Schizophrenia: Caused by a fault in programmed synaptic elimination during adolescence?
    • Feinberg I. Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence? JPsychiat Res. 1982;17:319-334.
    • (1982) JPsychiat Res. , vol.17 , pp. 319-334
    • Feinberg, I.1
  • 51
    • 0024388979 scopus 로고
    • Cortical pruning and the development of schizophrenia: A computer model
    • Hoffman RE, Dobscha SK. Cortical pruning and the development of schizophrenia: a computer model. Schizophr Bull. 1989;15:477-490.
    • (1989) Schizophr Bull. , vol.15 , pp. 477-490
    • Hoffman, R.E.1    Dobscha, S.K.2
  • 52
    • 0027397996 scopus 로고
    • Parallel distributed processing and the emergence of schizophrenic symptoms
    • Huffman RE, McGlashan TH. Parallel distributed processing and the emergence of schizophrenic symptoms. Schizophr Bull. 1993:19:119-140.
    • (1993) Schizophr Bull. , vol.19 , pp. 119-140
    • Huffman, R.E.1    McGlashan, T.H.2
  • 53
    • 0027972581 scopus 로고
    • An ultrastructural size principle
    • Pierce JP, Lewin GR. An ultrastructural size principle. Neuroscience. 1994;58: 441-446.
    • (1994) Neuroscience. , vol.58 , pp. 441-446
    • Pierce, J.P.1    Lewin, G.R.2
  • 54
    • 0024212095 scopus 로고
    • Mediodorsal nucleus: Areal, laminar, and tangential distribution of afferents and efferents in the frontal lobe of rhesus monkeys
    • Giguere M, Goldman-Rakic PS. Mediodorsal nucleus: areal, laminar, and tangential distribution of afferents and efferents in the frontal lobe of rhesus monkeys. J Comp Neurol. 1988:277:195-213.
    • (1988) J Comp Neurol. , vol.277 , pp. 195-213
    • Giguere, M.1    Goldman-Rakic, P.S.2
  • 55
    • 0019969807 scopus 로고
    • Interdigitation of contralateral and ipsilateral columnar projections to frontal association cortex in primates
    • Goldman-Rakic PS, Schwarte ML. Interdigitation of contralateral and ipsilateral columnar projections to frontal association cortex in primates. Science. 1982; 216:755-757.
    • (1982) Science. , vol.216 , pp. 755-757
    • Goldman-Rakic, P.S.1    Schwarte, M.L.2
  • 56
    • 0027398887 scopus 로고
    • Local circuit neurons of developing and mature macaque prefrontal cortex: Golgi and immunocytochemical characteristics
    • Lund JS, Lewis DA. Local circuit neurons of developing and mature macaque prefrontal cortex: golgi and immunocytochemical characteristics. J Comp Neurol. 1993:328:282-312.
    • (1993) J Comp Neurol. , vol.328 , pp. 282-312
    • Lund, J.S.1    Lewis, D.A.2
  • 58
    • 0026612361 scopus 로고
    • Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics
    • Benes FM, Vincent SL, Alsterberg G, Bird ED, SanGiovanni JP. Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics. J Neurosci. 1992:12:924-929.
    • (1992) J Neurosci. , vol.12 , pp. 924-929
    • Benes, F.M.1    Vincent, S.L.2    Alsterberg, G.3    Bird, E.D.4    Sangiovanni, J.P.5
  • 59
    • 0030331175 scopus 로고    scopus 로고
    • Up-regulation of GABA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects
    • Benes FM, Vincent SL, Marie A, Khan Y. Up-regulation of GABA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects. Neuroscience. 1996:75:1021-1031.
    • (1996) Neuroscience. , vol.75 , pp. 1021-1031
    • Benes, F.M.1    Vincent, S.L.2    Marie, A.3    Khan, Y.4


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