The glycosidation of xenobiotics and endogenous compounds: Versatility and redundancy in the UDP glycosyltransferase superfamily

Pharmacology and Therapeutics

Volumn 134, Issue 2, 2012, Pages 200-218

  Meech, Robyn ^a   Miners, John O ^a   Lewis, Benjamin C ^a   MacKenzie, Peter I ^a  

^a FLINDERS UNIVERSITY   (Australia)

Author keywords

Evolution and function; Glucuronide; Glycoside; UDP glucuronosyltransferase; UDP glycosyltransferase; UGT1; UGT2; UGT3; UGT8

Indexed keywords

GLUCOSIDE; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 2; GLUCURONOSYLTRANSFERASE 3; GLUCURONOSYLTRANSFERASE 3A; GLUCURONOSYLTRANSFERASE 3A1; GLUCURONOSYLTRANSFERASE 3A2; GLUCURONOSYLTRANSFERASE 5; GLUCURONOSYLTRANSFERASE 8; N ACETYLLACTOSAMINE SYNTHASE; SUGAR; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; XENOBIOTIC AGENT;

BODY FLUID; CATALYSIS; CELL TYPE; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME STRUCTURE; GENE STRUCTURE; GENOME; GLYCOSIDATION; HUMAN; LIPOPHILICITY; MAMMAL; MOLECULAR EVOLUTION; MOLECULAR WEIGHT; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; STRUCTURE ACTIVITY RELATION; VERTEBRATE;

ANIMALS; GLUCURONOSYLTRANSFERASE; GLYCOSIDES; HUMANS; XENOBIOTICS;

EID: 84859163679     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2012.01.009     Document Type: Review

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