-
1
-
-
0031843966
-
Interaction of periodate-oxidized UDP-glucuronic acid with recombinant human liver UDP-glucuronosyltransferase 1A6
-
Battaglia E, Terrier N, Mizeracka M, Senay C, Magdalou J, Fournel-Gigleux S, and Radominska-Pandya A (1998) Interaction of periodate-oxidized UDP-glucuronic acid with recombinant human liver UDP-glucuronosyltransferase 1A6. Drug Metab Dispos 26:812-817.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 812-817
-
-
Battaglia, E.1
Terrier, N.2
Mizeracka, M.3
Senay, C.4
Magdalou, J.5
Fournel-Gigleux, S.6
Radominska-Pandya, A.7
-
2
-
-
0034351172
-
Uridine 5′-diphosphoglucuronic acid (UDPGLcUA) in the human fetal liver, kidney and placenta
-
Cappiello M, Giuliani L, Rane A, and Pacifici GM (2000) Uridine 5′-diphosphoglucuronic acid (UDPGLcUA) in the human fetal liver, kidney and placenta. Eur J Drug Metab Pharmacokinet 25:161-163.
-
(2000)
Eur J Drug Metab Pharmacokinet
, vol.25
, pp. 161-163
-
-
Cappiello, M.1
Giuliani, L.2
Rane, A.3
Pacifici, G.M.4
-
5
-
-
0035197725
-
Interindividual variability in acetaminophen glucuronidation by human liver microsomes: Identification of relevant acetaminophen UDP- glucuronosyltransferase isoforms
-
Court MH, Duan SX, von Moltke LL, Greenblatt DJ, Patten CJ, Miners JO, and Mackenzie PI (2001) Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms. J Pharmacol Exp Ther 299:998-1006.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 998-1006
-
-
Court, M.H.1
Duan, S.X.2
Von Moltke, L.L.3
Greenblatt, D.J.4
Patten, C.J.5
Miners, J.O.6
Mackenzie, P.I.7
-
6
-
-
0034768913
-
Role of ATP and glycogen reserves in both paracetamol sulfation and glucuronidation by cultured precision-cut rat liver slices
-
Evdokimova E, Taper H, and Buc Calderon P (2001) Role of ATP and glycogen reserves in both paracetamol sulfation and glucuronidation by cultured precision-cut rat liver slices. Toxicol In Vitro 15:683-690.
-
(2001)
Toxicol In Vitro
, vol.15
, pp. 683-690
-
-
Evdokimova, E.1
Taper, H.2
Buc Calderon, P.3
-
7
-
-
0023146762
-
The enzymatic mechanism of glucuronidation catalyzed by two purified rat liver steroid UDP-glucuronosyltransferases
-
Falany CN, Green MD, and Tephly TR (1987) The enzymatic mechanism of glucuronidation catalyzed by two purified rat liver steroid UDP- glucuronosyltransferases. J Biol Chem 262:1218-1222.
-
(1987)
J Biol Chem
, vol.262
, pp. 1218-1222
-
-
Falany, C.N.1
Green, M.D.2
Tephly, T.R.3
-
8
-
-
0034966656
-
Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus
-
Gong QH, Cho JW, Huang T, Potter C, Gholami N, Basu NK, Kubota S, Carvalho S, Pennington MW, Owens IS, et al. (2001) Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus. Pharmacogenetics 11:357-368.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 357-368
-
-
Gong, Q.H.1
Cho, J.W.2
Huang, T.3
Potter, C.4
Gholami, N.5
Basu, N.K.6
Kubota, S.7
Carvalho, S.8
Pennington, M.W.9
Owens, I.S.10
-
9
-
-
0028948889
-
Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides
-
Green MD, Bishop WP, and Tephly TR (1995) Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides. Drug Metab Dispos 23:299-302.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 299-302
-
-
Green, M.D.1
Bishop, W.P.2
Tephly, T.R.3
-
10
-
-
0031765698
-
Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3
-
Green MD, King CD, Mojarrabi B, Mackenzie PI, and Tephly TR (1998) Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3. Drug Metab Dispos 26:507-512.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 507-512
-
-
Green, M.D.1
King, C.D.2
Mojarrabi, B.3
Mackenzie, P.I.4
Tephly, T.R.5
-
11
-
-
0034105896
-
In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model
-
Houston JB and Kenworthy KE (2000) In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model. Drug Metab Dispos 28:246-254.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 246-254
-
-
Houston, J.B.1
Kenworthy, K.E.2
-
12
-
-
0022459940
-
Depletion of hepatic UDP-glucuronic acid by drugs that are glucuronidated
-
Howell SR, Hazelton GA, and Klaassen CD (1986) Depletion of hepatic UDP-glucuronic acid by drugs that are glucuronidated. J Pharmacol Exp Ther 236:610-614.
-
(1986)
J Pharmacol Exp Ther
, vol.236
, pp. 610-614
-
-
Howell, S.R.1
Hazelton, G.A.2
Klaassen, C.D.3
-
13
-
-
0018239042
-
Enzymatic conjugation and hydrolysis of [18O]isoborneol glucuronide
-
Johnson LP and Fenselau C (1978) Enzymatic conjugation and hydrolysis of [18O]isoborneol glucuronide. Drug Metab Dispos 6:677-679.
-
(1978)
Drug Metab Dispos
, vol.6
, pp. 677-679
-
-
Johnson, L.P.1
Fenselau, C.2
-
14
-
-
0035873701
-
High-performance liquid chromatographic method combining radiochemical and ultraviolet detection for determination of low activities of uridine 5′-diphosphate-glucuronosyltransferase
-
Kaivosaari S, Salonen JS, Mortensen J, and Taskinen J (2001) High-performance liquid chromatographic method combining radiochemical and ultraviolet detection for determination of low activities of uridine 5′-diphosphate-glucuronosyltransferase. Anal Biochem 292:178-187.
-
(2001)
Anal Biochem
, vol.292
, pp. 178-187
-
-
Kaivosaari, S.1
Salonen, J.S.2
Mortensen, J.3
Taskinen, J.4
-
15
-
-
0021061756
-
Kinetic properties of the rat intestinal microsomal 1-naphthol: UDP-glucuronosyl transferase. Inhibition by UDP and UDP-N-acetylglucosamine
-
Koster AS and Noordhoek J (1983) Kinetic properties of the rat intestinal microsomal 1-naphthol: UDP-glucuronosyl transferase. Inhibition by UDP and UDP-N-acetylglucosamine. Biochim Biophys Acta 761:76-85.
-
(1983)
Biochim Biophys Acta
, vol.761
, pp. 76-85
-
-
Koster, A.S.1
Noordhoek, J.2
-
16
-
-
0037423299
-
Expression and characterization of recombinant human UDP glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than the other UGTs and was purified as an active dimeric enzyme
-
Kurkela M, Garcia-Horsman JA, Luukkanen L, Mörsky S, Taskinen J, Baumann M, Kostiainen R, Hirvonen J, and Finel M (2003) Expression and characterization of recombinant human UDP glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than the other UGTs and was purified as an active dimeric enzyme. J Biol Chem 278:3536-3544.
-
(2003)
J Biol Chem
, vol.278
, pp. 3536-3544
-
-
Kurkela, M.1
Garcia-Horsman, J.A.2
Luukkanen, L.3
Mörsky, S.4
Taskinen, J.5
Baumann, M.6
Kostiainen, R.7
Hirvonen, J.8
Finel, M.9
-
17
-
-
8844283291
-
The interactions between the N-terminal and C-terminal domains of the human UDP-glucuronosyltransferases are partly isoform-specific and may involve both monomers
-
Kurkela M, Hirvonen J, Kostiainen R, and Finel M (2004) The interactions between the N-terminal and C-terminal domains of the human UDP- glucuronosyltransferases are partly isoform-specific and may involve both monomers. Biochem Pharmacol 68:2443-2450.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 2443-2450
-
-
Kurkela, M.1
Hirvonen, J.2
Kostiainen, R.3
Finel, M.4
-
18
-
-
0041856580
-
Glucuronidation of anabolic androgenic steroids by recombinant human UDP-glucuronosyltransferases
-
Kuuranne T, Kurkela M, Thevis M, Schänzer W, Finel M, and Kostiainen R (2003) Glucuronidation of anabolic androgenic steroids by recombinant human UDP-glucuronosyltransferases. Drug Metab Dispos 31:1117-1124.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1117-1124
-
-
Kuuranne, T.1
Kurkela, M.2
Thevis, M.3
Schänzer, W.4
Finel, M.5
Kostiainen, R.6
-
19
-
-
0344178210
-
Enzyme-assisted synthesis and structural characterization of nitrocatechol glucuronides
-
Luukkanen L, Kilpelainen I, Kangas H, Ottoila P, Elovaara E, and Taskinen J (1999) Enzyme-assisted synthesis and structural characterization of nitrocatechol glucuronides. Bioconj Chem 10:150-154.
-
(1999)
Bioconj Chem
, vol.10
, pp. 150-154
-
-
Luukkanen, L.1
Kilpelainen, I.2
Kangas, H.3
Ottoila, P.4
Elovaara, E.5
Taskinen, J.6
-
20
-
-
0034942528
-
Glucuronidation of 1-hydroxypyrene by human liver microsomes and human UDPglucuronosyltransferases UGT1A6, UGT1A7 and UGT1A9: Development of a high-sensitivity glucuronidation assay for human tissue
-
Luukkanen L, Mikkola J, Forsman T, Taavitsainen P, Taskinen J, and Elovaara E (2001) Glucuronidation of 1-hydroxypyrene by human liver microsomes and human UDPglucuronosyltransferases UGT1A6, UGT1A7 and UGT1A9: development of a high-sensitivity glucuronidation assay for human tissue. Drug Metab Dispos 29:1096-1101.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1096-1101
-
-
Luukkanen, L.1
Mikkola, J.2
Forsman, T.3
Taavitsainen, P.4
Taskinen, J.5
Elovaara, E.6
-
21
-
-
0025236448
-
Expression of chimeric cDNAs in cell culture defines a region on UDP-glucuronosyltransferase involved in substrate selection
-
Mackenzie P (1990) Expression of chimeric cDNAs in cell culture defines a region on UDP-glucuronosyltransferase involved in substrate selection. J Biol Chem 265:3432-3435.
-
(1990)
J Biol Chem
, vol.265
, pp. 3432-3435
-
-
Mackenzie, P.1
-
22
-
-
8544224973
-
The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence
-
Mackenzie PI, Owens IS, Burchell B, Bock KW, Bairoch A, Belanger A, Fournel-Gigleux S, Green M, Hum DW, Iyanagi T, et al. (1997) The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics 7:255-269.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 255-269
-
-
Mackenzie, P.I.1
Owens, I.S.2
Burchell, B.3
Bock, K.W.4
Bairoch, A.5
Belanger, A.6
Fournel-Gigleux, S.7
Green, M.8
Hum, D.W.9
Iyanagi, T.10
-
23
-
-
4243182634
-
Human UDP-glucuronosyltransferase 1A1 is the primary enzyme responsible for the N-glucuronidation of N-hydroxy-PhIP in vitro
-
Malfatti MA and Felton JS (2004) Human UDP-glucuronosyltransferase 1A1 is the primary enzyme responsible for the N-glucuronidation of N-hydroxy-PhIP in vitro. Chem Res Toxicol 17:1137-1144.
-
(2004)
Chem Res Toxicol
, vol.17
, pp. 1137-1144
-
-
Malfatti, M.A.1
Felton, J.S.2
-
24
-
-
0025824215
-
Isolation and characterization of hyodeoxycholic acid UDP-glucuronosyltransferase from human liver
-
Matern H, Lappas N, and Matern S (1991) Isolation and characterization of hyodeoxycholic acid UDP-glucuronosyltransferase from human liver. Eur J Biochem 200:393-400.
-
(1991)
Eur J Biochem
, vol.200
, pp. 393-400
-
-
Matern, H.1
Lappas, N.2
Matern, S.3
-
25
-
-
0033675536
-
Importance of histidine residues for the function of the human liver UDP-glucuronosyltransferase UGT1A6: Evidence for the catalytic role of histidine 370
-
Ouzzine M, Antonio L, Burchell B, Netter P, Fournel-Gigleux S, and Magdalou J (2000) Importance of histidine residues for the function of the human liver UDP-glucuronosyltransferase UGT1A6: evidence for the catalytic role of histidine 370. Mol Pharmacol 58:1609-1615.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 1609-1615
-
-
Ouzzine, M.1
Antonio, L.2
Burchell, B.3
Netter, P.4
Fournel-Gigleux, S.5
Magdalou, J.6
-
26
-
-
0027749498
-
Determination of the human liver UDP-glucuronosyltransferase 2B4 domains involved in the binding of UDP-glucuronic acid using photoaffinity labeling of fusion proteins
-
Pillot T, Ouzzine M, Fournel-Giglieux S, Lafaurie C, Tebbi D, Treat S, Radominska A, Lester R, Siest G, and Magdalou J (1993) Determination of the human liver UDP-glucuronosyltransferase 2B4 domains involved in the binding of UDP-glucuronic acid using photoaffinity labeling of fusion proteins. Biochem Biophys Res Commun 197:785-791.
-
(1993)
Biochem Biophys Res Commun
, vol.197
, pp. 785-791
-
-
Pillot, T.1
Ouzzine, M.2
Fournel-Giglieux, S.3
Lafaurie, C.4
Tebbi, D.5
Treat, S.6
Radominska, A.7
Lester, R.8
Siest, G.9
Magdalou, J.10
-
27
-
-
0015523747
-
A study on the enzymatic mechanism of guinea-pig hepatic-microsomal bilirubin glucuronyl transferase
-
Potrepka RF and Spratt JL (1972) A study on the enzymatic mechanism of guinea-pig hepatic-microsomal bilirubin glucuronyl transferase. Eur J Biochem 29:433-439.
-
(1972)
Eur J Biochem
, vol.29
, pp. 433-439
-
-
Potrepka, R.F.1
Spratt, J.L.2
-
28
-
-
0017106709
-
Investigations on the kinetic properties of estrone glucuronyltransferase from pig kidney
-
Rao ML, Rao GS, and Breuer H (1976) Investigations on the kinetic properties of estrone glucuronyltransferase from pig kidney. Biochim Biophys Acta 452:89-100.
-
(1976)
Biochim Biophys Acta
, vol.452
, pp. 89-100
-
-
Rao, M.L.1
Rao, G.S.2
Breuer, H.3
-
29
-
-
0016554213
-
Morphine metabolism. IV. Studies on the mechanism of morphine: Uridine diphosphoglucuronyltransferase and its activation by bilirubin
-
Sanchez E and Tephly TR (1975) Morphine metabolism. IV. Studies on the mechanism of morphine: uridine diphosphoglucuronyltransferase and its activation by bilirubin. Mol Pharmacol 11:613-620.
-
(1975)
Mol Pharmacol
, vol.11
, pp. 613-620
-
-
Sanchez, E.1
Tephly, T.R.2
-
30
-
-
0027991904
-
Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation
-
Senafi SB, Clarke DJ, and Burchell B (1994) Investigation of the substrate specificity of a cloned expressed human bilirubin UDP- glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation. Biochem J 303:233-240.
-
(1994)
Biochem J
, vol.303
, pp. 233-240
-
-
Senafi, S.B.1
Clarke, D.J.2
Burchell, B.3
-
31
-
-
0033179447
-
Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4- methylcoumarin
-
Senay C, Battaglia E, Chen G, Breton R, Fournel-Gigleux S, Magdalou J, and Radominska-Pandya A (1999) Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4- methylcoumarin. Arch Biochem Biophys 368:75-84.
-
(1999)
Arch Biochem Biophys
, vol.368
, pp. 75-84
-
-
Senay, C.1
Battaglia, E.2
Chen, G.3
Breton, R.4
Fournel-Gigleux, S.5
Magdalou, J.6
Radominska-Pandya, A.7
-
32
-
-
0038532316
-
The effect of incubation conditions on the enzyme kinetics of UDP-glucuronosyltransferases
-
Soars MG, Ring BJ, and Wrighton SA (2003) The effect of incubation conditions on the enzyme kinetics of UDP-glucuronosyltransferases. Drug Metab Dispos 31:762-767.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 762-767
-
-
Soars, M.G.1
Ring, B.J.2
Wrighton, S.A.3
-
33
-
-
0034128936
-
Human UDP-glucuronosyltransferases: Metabolism, expression and disease
-
Tukey RH and Strassburg CP (2000) Human UDP-glucuronosyltransferases: metabolism, expression and disease. Annu Rev Pharmacol Toxicol 40:581-616.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
34
-
-
1842536833
-
Human UDP-glucuronosyltransferases: Isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents and inhibition by diclofenac and probenecid
-
Uchaipichat V, Mackenzie PI, Guo X-H, Gardner-Stephen D, Galetin A, Houston JB, and Miners JO (2004) Human UDP-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents and inhibition by diclofenac and probenecid. Drug Metab Dispos 32:413-423.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 413-423
-
-
Uchaipichat, V.1
Mackenzie, P.I.2
Guo, X.-H.3
Gardner-Stephen, D.4
Galetin, A.5
Houston, J.B.6
Miners, J.O.7
-
35
-
-
0015523047
-
Regulation of microsomal enzymes by phospholipids. V. Kinetic studies of hepatic uridine diphosphate-glucuronyltransferase
-
Vessey DA and Zakim D (1972) Regulation of microsomal enzymes by phospholipids. V. Kinetic studies of hepatic uridine diphosphate- glucuronyltransferase. J Biol Chem 247:3023-3028.
-
(1972)
J Biol Chem
, vol.247
, pp. 3023-3028
-
-
Vessey, D.A.1
Zakim, D.2
-
36
-
-
0036843701
-
Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1) catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human liver microsomes
-
Williams JA, Ring BJ, Cantrell VE, Campanale K, Jones DR, Hall SD, and Wrighton SA (2002) Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1) catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human liver microsomes. Drug Metab Dispos 30:1266-1273.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1266-1273
-
-
Williams, J.A.1
Ring, B.J.2
Cantrell, V.E.3
Campanale, K.4
Jones, D.R.5
Hall, S.D.6
Wrighton, S.A.7
-
37
-
-
0028331320
-
Mechanistic studies of uridine diphosphate glucuronosyltransferase
-
Yin H, Bennett G, and Jones JP (1994) Mechanistic studies of uridine diphosphate glucuronosyltransferase. Chem-Biol Interact 90:47-58.
-
(1994)
Chem-Biol Interact
, vol.90
, pp. 47-58
-
-
Yin, H.1
Bennett, G.2
Jones, J.P.3
|