Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4-methylcoumarin

Archives of Biochemistry and Biophysics

Volumn 368, Issue 1, 1999, Pages 75-84

  Senay, Claire ^b   Battaglia, Eric ^a   Chen, Guangping ^a   Breton, Robert ^c   Fournel Gigleux, Sylvie ^b   Magdalou, Jacques ^b   Radominska Pandya, Anna ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b Biopôle de l Université de Lorraine   (France)

^c LTR Charles Jully   (France)

Author keywords

7 azido 4 methylcoumarin; Enzyme active site; Photoaffinity labeling; Structure function relationships; UDP glucuronosyltransferase

Indexed keywords

5' O [[(2 DECANOYLAMINO 3 PHENYL PROPYLOXYCARBONYL)AMINO]SULFONYL] 2',3' O ISOPROPYLIDENEURIDINE; 7 AZIDO 4 METHYLCOUMARIN; BINDING PROTEIN; COUMARIN; GLUCURONIC ACID; GLUCURONOSYLTRANSFERASE; HYMECROMONE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCULATION; ENZYME ACTIVE SITE; GLUCURONIDATION; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

EID: 0033179447     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1999.1300     Document Type: Article

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