Phenylalanine90 and phenylalanine93 are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10

Steroids

Volumn 72, Issue 1, 2007, Pages 85-94

  Starlard Davenport, Athena ^a   Xiong, Yan ^a   Bratton, Stacie ^a   Gallus Zawada, Anna ^a   Finel, Moshe ^b   Radominska Pandya, Anna ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Binding site; Estrogens; Site directed mutagenesis; UGT1A10; UGTs

Indexed keywords

ESTRADIOL; ESTROGEN; ESTROGEN DERIVATIVE; ESTRONE; GLUCURONOSYLTRANSFERASE 1A10; PHENYLALANINE; VALINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; ESTROGEN BINDING; GLUCURONIDATION; ISOENZYME ANALYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NONHUMAN; PHOTOAFFINITY LABELING; PROTEIN MOTIF; SITE DIRECTED MUTAGENESIS;

ANIMALS; BINDING SITES; CHROMATOGRAPHY, LIQUID; ESTROGENS; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 33845917048     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2006.11.016     Document Type: Article

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