Oligodendrocyte-specific ceramide galactosyltransferase (CGT) expression phenotypically rescues CGT-deficient mice and demonstrates that CGT activity does not limit brain galactosylceramide level

GLIA

Volumn 52, Issue 3, 2005, Pages 190-198

  Zöller, Inge ^a   Büssow, Heinrich ^a   Gieselmann, Volkmar ^a   Eckhardt, Matthias ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

hydroxyceramide; Demyelination; Galactosylceramide; Sulfatide

Indexed keywords

CERAMIDE GALACTOSYLTRANSFERASE; GALACTOSYLCERAMIDE; GALACTOSYLTRANSFERASE; HYDROXY FATTY ACID; MYELIN; PROTEOLIPID; SPHINGOLIPID; SULFATIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BEHAVIOR DISORDER; BRAIN REGION; CERAMIDE GALACTOSYLTRANSFERASE DEFICIENCY; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMYELINATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; MOTOR DYSFUNCTION; MOUSE; MYELIN SHEATH; NERVE CELL; NONHUMAN; OLIGODENDROGLIA; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; BRAIN; BRAIN CHEMISTRY; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; FATTY ACIDS; FEMALE; GALACTOSYLCERAMIDES; GENE EXPRESSION REGULATION; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; MYELIN PROTEOLIPID PROTEIN; MYELIN SHEATH; N-ACYLSPHINGOSINE GALACTOSYLTRANSFERASE; NERVE FIBERS, MYELINATED; OLIGODENDROGLIA; PROMOTER REGIONS (GENETICS); TRANSGENES; UP-REGULATION;

EID: 30444435725     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20230     Document Type: Article

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