메뉴 건너뛰기




Volumn 5, Issue 7, 2006, Pages 1800-1806

The determinants of sensitivity and acquired resistance to gemcitabine differ in non-small cell lung cancer: A role of ABCC5 in gemcitabine sensitivity

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYCYTIDINE KINASE; GEMCITABINE; MULTIDRUG RESISTANCE PROTEIN 5; PEMETREXED; RIBONUCLEOTIDE REDUCTASE; SMALL INTERFERING RNA; ZAPRINAST;

EID: 33748306343     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0025     Document Type: Article
Times cited : (92)

References (25)
  • 1
    • 0036636579 scopus 로고    scopus 로고
    • Nucleoside analogues and nucleobases in cancer treatment
    • Galmarini CM, Mackey JR, Dumontet C. Nucleoside analogues and nucleobases in cancer treatment. Lancet Oncol 2002;3:415-24.
    • (2002) Lancet Oncol , vol.3 , pp. 415-424
    • Galmarini, C.M.1    Mackey, J.R.2    Dumontet, C.3
  • 2
    • 0028832342 scopus 로고
    • Gemcitabine: A modulator of intracellular nucleotide and deoxynucleotide metabolism
    • Heinemann V, Schulz L, Issels RD, Plunkett W. Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism. Semin Oncol 1995;22:11-8.
    • (1995) Semin Oncol , vol.22 , pp. 11-18
    • Heinemann, V.1    Schulz, L.2    Issels, R.D.3    Plunkett, W.4
  • 4
    • 0036462584 scopus 로고    scopus 로고
    • Determinants of resistance to 2′,2′-difluorodeoxycytidine (gemcitabine)
    • Bergman AM, Pinedo HM, Peters GJ. Determinants of resistance to 2′,2′-difluorodeoxycytidine (gemcitabine). Drug Resist Updat 2002;5: 19-33.
    • (2002) Drug Resist Updat , vol.5 , pp. 19-33
    • Bergman, A.M.1    Pinedo, H.M.2    Peters, G.J.3
  • 5
    • 0032188825 scopus 로고    scopus 로고
    • Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines
    • Mackey JR, Mani RS, Selner M, et al. Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines. Cancer Res 1998;58:4349-57.
    • (1998) Cancer Res , vol.58 , pp. 4349-4357
    • Mackey, J.R.1    Mani, R.S.2    Selner, M.3
  • 6
    • 5044225419 scopus 로고    scopus 로고
    • Determinants of sensitivity and resistance to gemcitabine: The roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer
    • Achiwa H, Oguri T, Sato S, Maeda H, Niimi T, Ueda R. Determinants of sensitivity and resistance to gemcitabine: the roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer. Cancer Sci 2004;95:753-7.
    • (2004) Cancer Sci , vol.95 , pp. 753-757
    • Achiwa, H.1    Oguri, T.2    Sato, S.3    Maeda, H.4    Niimi, T.5    Ueda, R.6
  • 7
    • 0028067217 scopus 로고
    • Development and molecular characterization of a 2′,2′-difluorodeoxycytidine-resistant variant of the human ovarian carcinoma cell line A2780
    • Ruiz van Haperen VWT, Veerman G, Eriksson S, et al. Development and molecular characterization of a 2′,2′-difluorodeoxycytidine-resistant variant of the human ovarian carcinoma cell line A2780. Cancer Res 1994; 54:4138-43.
    • (1994) Cancer Res , vol.54 , pp. 4138-4143
    • Ruiz van Haperen, V.W.T.1    Veerman, G.2    Eriksson, S.3
  • 8
    • 0033198464 scopus 로고    scopus 로고
    • Overexpression of ribonucleotide reductase as a mechanism of resistance to 2,2-difluorodeoxycytidine in the human KB cancer cell line
    • Goan YG, Zhou B, Hu E, Mi S, Yen Y. Overexpression of ribonucleotide reductase as a mechanism of resistance to 2,2-difluorodeoxycytidine in the human KB cancer cell line. Cancer Res 1999;59:4204-7.
    • (1999) Cancer Res , vol.59 , pp. 4204-4207
    • Goan, Y.G.1    Zhou, B.2    Hu, E.3    Mi, S.4    Yen, Y.5
  • 9
    • 2542530631 scopus 로고    scopus 로고
    • An increase in the expression of ribonucleotide reductase large subunit 1 is associated with gemcitabine resistance in non-small cell lung cancer cell lines
    • Davidson JD, Me L, Flagella M, Geeganage S, Gelbert LM, Slapak CA. An increase in the expression of ribonucleotide reductase large subunit 1 is associated with gemcitabine resistance in non-small cell lung cancer cell lines. Cancer Res 2004;64:3761-6.
    • (2004) Cancer Res , vol.64 , pp. 3761-3766
    • Davidson, J.D.1    Me, L.2    Flagella, M.3    Geeganage, S.4    Gelbert, L.M.5    Slapak, C.A.6
  • 10
    • 1242335471 scopus 로고    scopus 로고
    • The MRP-related and BCRP/ABCG2 multidrug resistance proteins: Biology, substrate specificity, and regulation
    • Haimeur A, Conseil G, Deeley RG, Cole SP. The MRP-related and BCRP/ABCG2 multidrug resistance proteins: biology, substrate specificity, and regulation. Curr Drug Metab 2004;5:21-53.
    • (2004) Curr Drug Metab , vol.5 , pp. 21-53
    • Haimeur, A.1    Conseil, G.2    Deeley, R.G.3    Cole, S.P.4
  • 11
    • 12944270590 scopus 로고    scopus 로고
    • Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs
    • Wijnholds J, Mol CAAM, van Deemter L, et al. Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs. Proc Natl Acad Sci U S A 2000;97:7476-81.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 7476-7481
    • Wijnholds, J.1    Mol, C.A.A.M.2    van Deemter, L.3
  • 12
    • 0037816114 scopus 로고    scopus 로고
    • Human multidrug resistance protein 5 (MRP5) confers resistance to gemcitabine
    • Davidson JD, Ma L, Iverson PW, et al. Human multidrug resistance protein 5 (MRP5) confers resistance to gemcitabine. Proc Am Assoc Cancer Res 2002;43:780-1.
    • (2002) Proc Am Assoc Cancer Res , vol.43 , pp. 780-781
    • Davidson, J.D.1    Ma, L.2    Iverson, P.W.3
  • 13
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
    • Schiller JH, Harrington D, Belani CP, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med 2002;346:92-8.
    • (2002) N Engl J Med , vol.346 , pp. 92-98
    • Schiller, J.H.1    Harrington, D.2    Belani, C.P.3
  • 14
    • 0034094338 scopus 로고    scopus 로고
    • Increased expression of the MRP5 gene is associated with exposure to platinum drugs in lung cancer
    • Oguri T, Isobe T, Suzuki T, et al. Increased expression of the MRP5 gene is associated with exposure to platinum drugs in lung cancer. Int J Cancer 2000;86:95-100.
    • (2000) Int J Cancer , vol.86 , pp. 95-100
    • Oguri, T.1    Isobe, T.2    Suzuki, T.3
  • 15
    • 0035882554 scopus 로고    scopus 로고
    • Association between expression of the MRP3 gene and exposure to platinum drugs in lung cancer
    • Oguri T, Isobe T, Fujitaka K, Ishikawa N, Kohno N. Association between expression of the MRP3 gene and exposure to platinum drugs in lung cancer. Int J Cancer 2001;93:584-9.
    • (2001) Int J Cancer , vol.93 , pp. 584-589
    • Oguri, T.1    Isobe, T.2    Fujitaka, K.3    Ishikawa, N.4    Kohno, N.5
  • 16
    • 0034730755 scopus 로고    scopus 로고
    • The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides
    • Jedlitschky G, Burchell B, Keppler D. The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides. J Biol Chem 2000;275:30069-74.
    • (2000) J Biol Chem , vol.275 , pp. 30069-30074
    • Jedlitschky, G.1    Burchell, B.2    Keppler, D.3
  • 17
    • 2442451440 scopus 로고    scopus 로고
    • Synergistic cytotoxicity and pharmacogenetics of gemcitabine and pemetrexed combination in pancreatic cancer cell lines
    • Giovannetti E, Mey V, Danesi R, Mosca I, Del Tacca M. Synergistic cytotoxicity and pharmacogenetics of gemcitabine and pemetrexed combination in pancreatic cancer cell lines. Clin Cancer Res 2004;10: 2936-43.
    • (2004) Clin Cancer Res , vol.10 , pp. 2936-2943
    • Giovannetti, E.1    Mey, V.2    Danesi, R.3    Mosca, I.4    Del Tacca, M.5
  • 18
    • 22344449812 scopus 로고    scopus 로고
    • Cellular and pharmacogenetics foundation of synergistic interaction of pemetrexed and gemcitabine in human non-small-cell lung cancer cells
    • Giovannetti E, Mey V, Nannizzi S, et al. Cellular and pharmacogenetics foundation of synergistic interaction of pemetrexed and gemcitabine in human non-small-cell lung cancer cells. Mol Pharmacol 2005;68: 110-8.
    • (2005) Mol Pharmacol , vol.68 , pp. 110-118
    • Giovannetti, E.1    Mey, V.2    Nannizzi, S.3
  • 19
    • 0038752694 scopus 로고    scopus 로고
    • Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5
    • Reid G, Wielinga P, Zelcer N, et al. Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5. Mol Pharmacol 2003;63:1094-103.
    • (2003) Mol Pharmacol , vol.63 , pp. 1094-1103
    • Reid, G.1    Wielinga, P.2    Zelcer, N.3
  • 20
    • 20044383925 scopus 로고    scopus 로고
    • The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites
    • Pratt S, Shepard RL, Kandasamy RA, Johnston PA, Perry W III, Dantzig AH. The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites. Mol Cancer Ther 2005;4:855-63.
    • (2005) Mol Cancer Ther , vol.4 , pp. 855-863
    • Pratt, S.1    Shepard, R.L.2    Kandasamy, R.A.3    Johnston, P.A.4    Perry III, W.5    Dantzig, A.H.6
  • 21
    • 0345688175 scopus 로고    scopus 로고
    • Nucleoside anticancer drugs: The role of nucleoside transporters in resistance to cancer chemotherapy
    • Damaraju VL, Damaraju S, Young JD, et al. Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy. Oncogene 2003;22:7524-36.
    • (2003) Oncogene , vol.22 , pp. 7524-7536
    • Damaraju, V.L.1    Damaraju, S.2    Young, J.D.3
  • 22
    • 12144285914 scopus 로고    scopus 로고
    • Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients
    • Rosell R, Denenberg KD, Alberola V, et al. Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Clin Cancer Res 2004;10: 1318-25.
    • (2004) Clin Cancer Res , vol.10 , pp. 1318-1325
    • Rosell, R.1    Denenberg, K.D.2    Alberola, V.3
  • 23
    • 24944485165 scopus 로고    scopus 로고
    • Randomized phase II trial of three schedules of pemetrexed and gemcitabine as front-line therapy for advanced non-small-cell lung cancer
    • Ma CX, Nair S, Thomas S, et al. Randomized phase II trial of three schedules of pemetrexed and gemcitabine as front-line therapy for advanced non-small-cell lung cancer. J Clin Oncol 2005;23:5929-37.
    • (2005) J Clin Oncol , vol.23 , pp. 5929-5937
    • Ma, C.X.1    Nair, S.2    Thomas, S.3
  • 24
    • 0037437762 scopus 로고    scopus 로고
    • Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance
    • Mansson E, Flordal E, Liliemark J, et al. Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance. Biochem Pharmacol 2003;65:237-47.
    • (2003) Biochem Pharmacol , vol.65 , pp. 237-247
    • Mansson, E.1    Flordal, E.2    Liliemark, J.3
  • 25
    • 0033406797 scopus 로고    scopus 로고
    • Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line
    • Mansson E, Spasokoukotskaja T, Sallstrom J, Eriksson S, Albertioni F. Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line. Cancer Res 1999;59: 5956-63.
    • (1999) Cancer Res , vol.9 , pp. 5956-5963
    • Mansson, E.1    Spasokoukotskaja, T.2    Sallstrom, J.3    Eriksson, S.4    Albertioni, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.