Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells

Cancer Research

Volumn 61, Issue 18, 2001, Pages 6635-6639

  Honjo, Y ^a   Hrycyna, C A ^a   Yan, Q W ^a   Medina Perez W Y ^a   Robey, R W ^a   Van de Laar, A ^a   Litman, T ^a   Dean, M ^a   Bates, S E ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANTHRACYCLINE; DNA; DOXORUBICIN; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN; MXR BCRP ABCP PROTEIN; RHODAMINE 123; TOPOTECAN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CROSS RESISTANCE; CYTOTOXICITY; ENZYME SPECIFICITY; GENE MUTATION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; VACCINIA VIRUS; VIRUS EXPRESSION;

ATP-BINDING CASSETTE TRANSPORTERS; BREAST NEOPLASMS; CAMPTOTHECIN; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GENES, MDR; GENETIC VECTORS; HELA CELLS; HUMANS; MITOXANTRONE; MUTATION; NEOPLASM PROTEINS; RHODAMINE 123; RNA, MESSENGER; SUBSTRATE SPECIFICITY; TOPOTECAN; TRANSFECTION; TUMOR CELLS, CULTURED; VACCINIA VIRUS;

EID: 0035884595     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

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