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Volumn 272, Issue 2 41-2, 1997, Pages

Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)

Author keywords

3' azido 3' deoxythymidine; adenosine; deoxyadenosine; kidney nucleoside transport system N2 cit; Xenopus oocyte

Indexed keywords

COMPLEMENTARY DNA;

EID: 0030938889     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1997.272.2.c707     Document Type: Article
Times cited : (222)

References (37)
  • 2
    • 0027360690 scopus 로고
    • Nucleoside transport in normal and neoplastic cells
    • Belt, J. A., N. M. Marina, and D. A. Phelps. Nucleoside transport in normal and neoplastic cells. Adv. Enzyme Regul. 33: 235-252, 1993.
    • (1993) Adv. Enzyme Regul. , vol.33 , pp. 235-252
    • Belt, J.A.1    Marina, N.M.2    Phelps, D.A.3
  • 3
    • 0025046531 scopus 로고
    • Sodium-adenosine cotransport in brush-border membranes from rabbit ileum
    • Gastrointest. Liver Physiol. 22
    • Betcher, S. L., J. N. Forrest, Jr., R. G. Knickelbein, and J. W. Dobbins. Sodium-adenosine cotransport in brush-border membranes from rabbit ileum. Am. J. Physiol. 259 (Gastrointest. Liver Physiol. 22): G504-G510, 1990.
    • (1990) Am. J. Physiol. , vol.259
    • Betcher, S.L.1    Forrest Jr., J.N.2    Knickelbein, R.G.3    Dobbins, J.W.4
  • 4
    • 0029100025 scopus 로고
    • Cloning and mapping of a human gene (TBX2) sharing a highly conserved protein motif with the Drosophila omb gene
    • Campbell, C., K. Goodrich, G. Casey, and B. Beatty. Cloning and mapping of a human gene (TBX2) sharing a highly conserved protein motif with the Drosophila omb gene. Genomics 28: 255-260, 1995.
    • (1995) Genomics , vol.28 , pp. 255-260
    • Campbell, C.1    Goodrich, K.2    Casey, G.3    Beatty, B.4
  • 6
    • 0026767460 scopus 로고
    • A nucleoside transporter is functionally linked to ectonucleotidases in rat liver canalicular membrane
    • Che, M., T. Nishida, Z. Gatmaitan, and I. M. Arias. A nucleoside transporter is functionally linked to ectonucleotidases in rat liver canalicular membrane. J. Biol. Chem. 267: 9684-9688, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 9684-9688
    • Che, M.1    Nishida, T.2    Gatmaitan, Z.3    Arias, I.M.4
  • 8
    • 0027160955 scopus 로고
    • Current use of anti-HIV drugs in AIDS
    • Clumeck, N. Current use of anti-HIV drugs in AIDS. J. Antimicrobial. Chemother. 32, Suppl. A: 133-138, 1993.
    • (1993) J. Antimicrobial. Chemother. , vol.32 , Issue.SUPPL. A , pp. 133-138
    • Clumeck, N.1
  • 9
    • 0028272006 scopus 로고
    • Cloning of the nupC gene of Escherichia coli encoding a nucleoside transport system and identification of an adjacent insertion element, IS186
    • Craig, J. E., Y. Zhang, and M. P. Gallagher. Cloning of the nupC gene of Escherichia coli encoding a nucleoside transport system and identification of an adjacent insertion element, IS186. Mol. Microbiol. 11: 1159-1168, 1994.
    • (1994) Mol. Microbiol. , vol.11 , pp. 1159-1168
    • Craig, J.E.1    Zhang, Y.2    Gallagher, M.P.3
  • 10
    • 0030015533 scopus 로고    scopus 로고
    • Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1 rat) by transient expression in cultured mammalian cells
    • Fang, X., F. E. Parkinson, D. A. Mowles, J. D. Young, and C. E. Cass. Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1 rat) by transient expression in cultured mammalian cells. Biochem. J. 317: 457-465, 1996.
    • (1996) Biochem. J. , vol.317 , pp. 457-465
    • Fang, X.1    Parkinson, F.E.2    Mowles, D.A.3    Young, J.D.4    Cass, C.E.5
  • 11
    • 0025276615 scopus 로고
    • Isolation and characterization of an ether glucuronide of zidovudine, a major metabolite in monkeys and humans
    • Good, S. S., C. S., Koble, R. Crouch, R. L. Rideout, and P. De Miranda. Isolation and characterization of an ether glucuronide of zidovudine, a major metabolite in monkeys and humans. Drug Metab. Disp. 18: 321-326, 1990.
    • (1990) Drug Metab. Disp. , vol.18 , pp. 321-326
    • Good, S.S.1    Koble, C.S.2    Crouch, R.3    Rideout, R.L.4    De Miranda, P.5
  • 12
    • 0026501706 scopus 로고
    • Effect of 3′-azido-3′-deoxythymidine (AZT) on organic ion transport in rat renal brush border membrane vesicles
    • Griffiths, D. A., S. D. Hall, and P. P. Sokol. Effect of 3′-azido-3′-deoxythymidine (AZT) on organic ion transport in rat renal brush border membrane vesicles. J. Pharmacol. Exp. Ther. 260: 128-133, 1992.
    • (1992) J. Pharmacol. Exp. Ther. , vol.260 , pp. 128-133
    • Griffiths, D.A.1    Hall, S.D.2    Sokol, P.P.3
  • 13
    • 0027299916 scopus 로고
    • +-nucleoside transport in brush border membrane vesicles from human kidney
    • +-nucleoside transport in brush border membrane vesicles from human kidney. Biochim. Biophys. Acta 1149: 202-208, 1993.
    • (1993) Biochim. Biophys. Acta , vol.1149 , pp. 202-208
    • Gutierrez, M.M.1    Giacomini, K.M.2
  • 14
    • 0028126585 scopus 로고
    • Expression of a human renal sodium nucleoside cotransporter in Xenopus laevis oocytes
    • Gutierrez, M. M., and K. M. Giacomini. Expression of a human renal sodium nucleoside cotransporter in Xenopus laevis oocytes. Biochem. Pharmacol. 48: 2251-2253, 1994.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 2251-2253
    • Gutierrez, M.M.1    Giacomini, K.M.2
  • 15
    • 0027305423 scopus 로고
    • Functional expression of Na-dependent nucleoside transport systems of rat intestine in isolated oocytes of Xenopus laevis. Demonstration that rat jejunum expresses the purine-selective system N1 (cif) and a second novel system N3 having broad specificity for purine and pyrimidine nucleosides
    • Huang, Q.-Q., C. M. Harvey, A. R. P. Paterson, C. E. Cass, and J. D. Young. Functional expression of Na-dependent nucleoside transport systems of rat intestine in isolated oocytes of Xenopus laevis. Demonstration that rat jejunum expresses the purine-selective system N1 (cif) and a second novel system N3 having broad specificity for purine and pyrimidine nucleosides. J. Biol. Chem. 268: 20613-20619, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 20613-20619
    • Huang, Q.-Q.1    Harvey, C.M.2    Paterson, A.R.P.3    Cass, C.E.4    Young, J.D.5
  • 16
    • 0028362987 scopus 로고
    • Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein
    • Huang, Q.-Q., S. Y. M. Yao, M. W. L. Ritzel, A. R. P. Paterson, C. E. Cass, and J. D. Young. Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein. J. Biol. Chem. 269: 17757-17760, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17757-17760
    • Huang, Q.-Q.1    Yao, S.Y.M.2    Ritzel, M.W.L.3    Paterson, A.R.P.4    Cass, C.E.5    Young, J.D.6
  • 19
    • 0019955093 scopus 로고
    • Renal handling of 2′-deoxyadenosine and adenosine in humans and mice
    • Kuttesch, J. F., and J. A. Nelson. Renal handling of 2′-deoxyadenosine and adenosine in humans and mice. Cancer Chemother. Pharmacol. 8: 221-229, 1982.
    • (1982) Cancer Chemother. Pharmacol. , vol.8 , pp. 221-229
    • Kuttesch, J.F.1    Nelson, J.A.2
  • 20
    • 0023813298 scopus 로고
    • Purification of the human erythrocyte nucleoside transporter by immunoaffinity chromatography
    • Kwong, F. Y. P., A. Davies, C.-M. Tse, J. D. Young, P. J. F. Henderson, and S. A. Baldwin. Purification of the human erythrocyte nucleoside transporter by immunoaffinity chromatography. Biochem. J. 255: 243-249, 1988.
    • (1988) Biochem. J. , vol.255 , pp. 243-249
    • Kwong, F.Y.P.1    Davies, A.2    Tse, C.-M.3    Young, J.D.4    Henderson, P.J.F.5    Baldwin, S.A.6
  • 24
    • 0020528994 scopus 로고
    • Renal secretion of purine nucleosides and their analogs in mice
    • Nelson, J. A., J. F. Kuttesch, and B. H. Herbert. Renal secretion of purine nucleosides and their analogs in mice. Biochem. Pharmacol. 32: 2323-2327, 1983.
    • (1983) Biochem. Pharmacol. , vol.32 , pp. 2323-2327
    • Nelson, J.A.1    Kuttesch, J.F.2    Herbert, B.H.3
  • 25
    • 9444266170 scopus 로고
    • Molecular cloning and expression of SNST1, a renal sodium/nucleoside cotransporter
    • Pajor, A. M. Molecular cloning and expression of SNST1, a renal sodium/nucleoside cotransporter (Abstract). Drug Dev. Res. 31: 305, 1994.
    • (1994) Drug Dev. Res. , vol.31 , pp. 305
    • Pajor, A.M.1
  • 26
    • 0026761353 scopus 로고
    • +/nucleoside cotransporter. A member of the SGLT family
    • +/nucleoside cotransporter. A member of the SGLT family. J. Biol. Chem. 267: 3557-3560, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3557-3560
    • Pajor, A.M.1    Wright, E.R.2
  • 27
    • 0026586134 scopus 로고
    • Mechanism and site dependency of intestinal mucosal transport and metabolism of thymidine analogs
    • Park, G. B., and A. K. Mitra. Mechanism and site dependency of intestinal mucosal transport and metabolism of thymidine analogs. Pharm. Res. 9: 326-331, 1992.
    • (1992) Pharm. Res. , vol.9 , pp. 326-331
    • Park, G.B.1    Mitra, A.K.2
  • 29
    • 0026605647 scopus 로고
    • Nucleoside analogues as chemotherapeutic agents: A review
    • Perigaud, C., G. Gosselin, and J. L. Imbach. Nucleoside analogues as chemotherapeutic agents: a review. Nucleosides Nucleotides 11: 903-945, 1992.
    • (1992) Nucleosides Nucleotides , vol.11 , pp. 903-945
    • Perigaud, C.1    Gosselin, G.2    Imbach, J.L.3
  • 30
    • 0025878633 scopus 로고
    • +-dependent, concentrative nucleoside transport in rat marcophages. Specificity for natural nucleosides and nucleoside analogs, including dideoxynucleosides, and comparison of nucleoside transport in rat, mouse and human macrophages
    • +-dependent, concentrative nucleoside transport in rat marcophages. Specificity for natural nucleosides and nucleoside analogs, including dideoxynucleosides, and comparison of nucleoside transport in rat, mouse and human macrophages. Biochem. Pharmacol. 42: 247-252, 1991.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 247-252
    • Plagemann, P.G.W.1
  • 32
    • 0021447832 scopus 로고
    • Adenosine transport in perfused rat kidney and renal cortical membrane vesicles
    • Renal Fluid Electrolyte Physiol. 15
    • Trimble, M. E., and R. Coulson. Adenosine transport in perfused rat kidney and renal cortical membrane vesicles. Am. J. Physiol. 246 (Renal Fluid Electrolyte Physiol. 15): F794-F803, 1984.
    • (1984) Am. J. Physiol. , vol.246
    • Trimble, M.E.1    Coulson, R.2
  • 33
    • 0024263350 scopus 로고
    • Sodium-dependent nucleoside transport in mouse intestinal epithelial cells
    • Vijayalakshmi, D., and J. A. Belt. Sodium-dependent nucleoside transport in mouse intestinal epithelial cells. J. Biol. Chem. 263: 19419-19423, 1988.
    • (1988) J. Biol. Chem. , vol.263 , pp. 19419-19423
    • Vijayalakshmi, D.1    Belt, J.A.2
  • 34
    • 0024430047 scopus 로고
    • Characterization of sodium-dependent and sodium-independent nucleoside transport systems in rabbit brush-border and basolateral plasma-membrane vesicles from renal outer cortex
    • Williams, T. C., A. J. Doherty, D. A. Griffith, and S. M. Jarvis. Characterization of sodium-dependent and sodium-independent nucleoside transport systems in rabbit brush-border and basolateral plasma-membrane vesicles from renal outer cortex. Biochem. J. 264: 223-231, 1989.
    • (1989) Biochem. J. , vol.264 , pp. 223-231
    • Williams, T.C.1    Doherty, A.J.2    Griffith, D.A.3    Jarvis, S.M.4
  • 35
    • 0028293655 scopus 로고
    • Further characterization of the sodium-dependent nucleoside transporter (N3) in choroid plexus from rabbit
    • Wu, X., M. M. Gutierrez, and K. M. Giacomini. Further characterization of the sodium-dependent nucleoside transporter (N3) in choroid plexus from rabbit. Biochim. Biophys. Acta 1191: 190-196, 1994.
    • (1994) Biochim. Biophys. Acta , vol.1191 , pp. 190-196
    • Wu, X.1    Gutierrez, M.M.2    Giacomini, K.M.3
  • 36
    • 0029812857 scopus 로고    scopus 로고
    • Transport of the antiviral nucleoside analogs 3′-azido-3′-deoxythymidine (AZT) and 2′,3′-dideoxycytidine (ddC) by a recombinant nucleoside transporter (rCNT1) expressed in Xenopus oocytes
    • Yao, S. Y. M., C. E. Cass, and J. D. Young. Transport of the antiviral nucleoside analogs 3′-azido-3′-deoxythymidine (AZT) and 2′,3′-dideoxycytidine (ddC) by a recombinant nucleoside transporter (rCNT1) expressed in Xenopus oocytes. Mol. Pharmacol. 50: 388-393, 1996.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 388-393
    • Yao, S.Y.M.1    Cass, C.E.2    Young, J.D.3
  • 37
    • 0030465008 scopus 로고    scopus 로고
    • Transport of adenosine by recombinant purine- and pyrimidine-selective sodium/nucleoside cotransporters from rat jejunum expressed in Xenopus laevis oocytes
    • In press
    • Yao, S. Y. M., A. M. L. Ng, M. W. L. Ritzel, C. E. Cass, and J. D. Young. Transport of adenosine by recombinant purine- and pyrimidine-selective sodium/nucleoside cotransporters from rat jejunum expressed in Xenopus laevis oocytes. Mol. Pharmacol. In press.
    • Mol. Pharmacol.
    • Yao, S.Y.M.1    Ng, A.M.L.2    Ritzel, M.W.L.3    Cass, C.E.4    Young, J.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.