Dissection of drug-binding-induced conformational changes in P-glycoprotein

European Journal of Biochemistry

Volumn 255, Issue 2, 1998, Pages 383-390

  Wang, Guichun ^a   Pincheira, Roxana ^a   Zhang, Jian Ting ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Conformational change; Multidrug resistance; P glycoprotein; Proteolysis profile; Topology

Indexed keywords

ADENOSINE TRIPHOSPHATE; COLCHICINE; CYTOTOXIC AGENT; DOXORUBICIN; GLYCOPROTEIN P; NUCLEOTIDE; VERAPAMIL; VINBLASTINE;

ARTICLE; BINDING SITE; CANCER CELL; CELL LINE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG BINDING; DRUG TRANSPORT; HUMAN; HUMAN CELL; IN VITRO STUDY; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS;

BINDING SITES; CATALYSIS; CELL MEMBRANE; COLCHICINE; DOXORUBICIN; HUMANS; KINETICS; METHOTREXATE; MODELS, MOLECULAR; P-GLYCOPROTEIN; PROTEIN CONFORMATION; TRYPSIN; TUMOR CELLS, CULTURED; VINBLASTINE;

EID: 0032528075     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2550383.x     Document Type: Article

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