Chitosan and its derivatives as nanocarriers for siRNA delivery

Journal of Drug Delivery Science and Technology

Volumn 22, Issue 1, 2012, Pages 29-42

  Al Qadi, S ^a   Grenha, A ^b   Remunan Lopez C ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b UNIVERSITY OF ALGARVE   (Portugal)

Author keywords

Chitosan; Chitosan derivatives; Formulation parameters; Gene silencing; Nanocarriers; SiRNA delivery

Indexed keywords

ANTINEOPLASTIC AGENT; ARGINYLGLYCYLASPARTIC ACID; CHITOSAN; CHITOSAN DERIVATIVE; CHOLANIC ACID DERIVATIVE; CROSS LINKING REAGENT; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EUDRAGIT; GLYCOLCHITOSAN; HYALURONIC ACID; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOCKED NUCLEIC ACID; MACROGOL; MITOMYCIN; NANOCARRIER; POLY(GAMMA GLUTAMIC ACID); POLYARGININE; POLYETHYLENEIMINE; POLYGLACTIN; POLYLYSINE; POLYMER; QUANTUM DOT; RADIOPROTECTIVE AGENT; RESPIRATORY SYNCYTIAL VIRUS VACCINE; SMALL INTERFERING LOCKED NUCLEIC ACID; SMALL INTERFERING RNA; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; TRIMETHYLCHITOSAN; UNCLASSIFIED DRUG;

BIOCOMPATIBILITY; BIODEGRADATION; BREAST CANCER; BRONCHIOLITIS; CANCER RESISTANCE; CELL MEMBRANE; CELL MIGRATION; CELL TRANSPORT; CELL VIABILITY; CHEMICAL MODIFICATION; COACERVATION; COMPLEX FORMATION; CONTROLLED DRUG RELEASE; CYTOTOXICITY; DEACETYLATION; DEACETYLATION DEGREE; DOWN REGULATION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG PENETRATION; DRUG POTENTIATION; DRUG SAFETY; ENCAPSULATION; ENDOCYTOSIS; ENDOSOME; FIBROSIS; FREEZE DRYING; GELATION; GENE SILENCING; GENE VECTOR; HUMAN; HYDROGEN BOND; IMMUNOGENICITY; IN VIVO GENE TRANSFER; INNATE IMMUNITY; INTERNALIZATION; IONIC STRENGTH; LYSOSOME; MELANOMA; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE METABOLISM; OVARY CANCER; PARTICLE SIZE; PH; POLYMERIZATION; PROSTATE CANCER; PROTON TRANSPORT; RADIATION INDUCED FIBROSIS; RADIATION INJURY; REVIEW; RNA BINDING; RNA INTERFERENCE; RNA SEQUENCE; RNA STABILITY; SHELF LIFE; ZETA POTENTIAL;

EID: 84857405019     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(12)50003-1     Document Type: Review

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