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Volumn 12, Issue 1, 2005, Pages 41-57

Chitosan-based particles as controlled drug delivery systems

Author keywords

Chitosan; Drug Delivery; Microspheres; Polyanions; Self Assemblies

Indexed keywords

CHITOSAN;

EID: 11244281032     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.1080/10717540590889781     Document Type: Review
Times cited : (475)

References (125)
  • 1
    • 0028108163 scopus 로고
    • Preparation and evaluation of cross-linked chitosan microspheres containing furosemide
    • Akbuga, J., and Durmaz, G. 1994. Preparation and evaluation of cross-linked chitosan microspheres containing furosemide. Intl. J. Pharm. 111:217-222.
    • (1994) Intl. J. Pharm. , vol.111 , pp. 217-222
    • Akbuga, J.1    Durmaz, G.2
  • 2
    • 11244259622 scopus 로고    scopus 로고
    • 1997. Stabilization of colloidal systems by the formation of ionic lipid-polysaccharide complexes. EP 0 771 566 A1
    • Alonso, M. J., Calvo, P., Remunan, C., and Jato, J. L. V. 1997. Stabilization of colloidal systems by the formation of ionic lipid-polysaccharide complexes. EP 0 771 566 A1
    • Alonso, M.J.1    Calvo, P.2    Remunan, C.3    Jato, J.L.V.4
  • 3
    • 11244282810 scopus 로고    scopus 로고
    • 1998. Application of nanoparticles based on hydrophilic polymers as pharmaceutical forms. EP 0 860 166 A1
    • Alonso, M. J., Calvo, P., Remunan, C., and Jato, J. L. V. 1998. Application of nanoparticles based on hydrophilic polymers as pharmaceutical forms. EP 0 860 166 A1.
    • Alonso, M.J.1    Calvo, P.2    Remunan, C.3    Jato, J.L.V.4
  • 4
    • 0028071051 scopus 로고
    • Effect of chitosan on the permeability of mono layers of intestinal epithelial cells (Caco-2)
    • Artursson, A., Lindmark, T., Davis, S. S., and Illurn, L. 1994. Effect of chitosan on the permeability of mono layers of intestinal epithelial cells (Caco-2). Pharm. Res. 11:1358-1361.
    • (1994) Pharm. Res. , vol.11 , pp. 1358-1361
    • Artursson, A.1    Lindmark, T.2    Davis, S.S.3    Illurn, L.4
  • 5
    • 0000521032 scopus 로고
    • Evaluation of the biological properties of different wound dressing materials
    • Bersch, P. C., Nies, B., and Liebendorfer, A. 1995. Evaluation of the biological properties of different wound dressing materials. J. Mater. Sci. Med. 6:231-240.
    • (1995) J. Mater. Sci. Med. , vol.6 , pp. 231-240
    • Bersch, P.C.1    Nies, B.2    Liebendorfer, A.3
  • 6
    • 0029830736 scopus 로고    scopus 로고
    • Influence of cross-linking on the acid stability and physicochemical properties of chitosan microspheres
    • Berthold, A., Cremer, K., and Kreuter, J. 1996. Influence of cross-linking on the acid stability and physicochemical properties of chitosan microspheres. STP Pharm. Sci. 6:358-364.
    • (1996) STP Pharm. Sci. , vol.6 , pp. 358-364
    • Berthold, A.1    Cremer, K.2    Kreuter, J.3
  • 7
    • 0029969540 scopus 로고    scopus 로고
    • Preparation and characterization of chitosan microspheres as drug carrier for prednisolone sodium phosphate as model for anti-inflammatory drugs
    • Berthold, A., Cremer, K., and Kreuter, J. 1996a. Preparation and characterization of chitosan microspheres as drug carrier for prednisolone sodium phosphate as model for anti-inflammatory drugs. J. Control. Rel. 39:17-25.
    • (1996) J. Control. Rel. , vol.39 , pp. 17-25
    • Berthold, A.1    Cremer, K.2    Kreuter, J.3
  • 8
    • 0031395214 scopus 로고    scopus 로고
    • Development and characterization of protein-loaded poly (lactide-co-glycolide) nanospheres
    • Blanco, D., and Alonso, M. J. 1997. Development and characterization of protein-loaded poly (lactide-co-glycolide) nanospheres. Euro. J. Pharm. Biopharm. 43:287-294.
    • (1997) Euro. J. Pharm. Biopharm. , vol.43 , pp. 287-294
    • Blanco, D.1    Alonso, M.J.2
  • 9
    • 0024371139 scopus 로고
    • A novel approach to the delivery of microparticles or nanoparticles
    • Bodmeier, R., Chen, H., and Paeratakul, O. 1989. A novel approach to the delivery of microparticles or nanoparticles. Pharm. Res. 6:413-417.
    • (1989) Pharm. Res. , vol.6 , pp. 413-417
    • Bodmeier, R.1    Chen, H.2    Paeratakul, O.3
  • 10
    • 0035813684 scopus 로고    scopus 로고
    • Chitosan for gene delivery
    • Borchard, G. 2001. Chitosan for gene delivery. Adv. Drug Del. Rev. 52:145-150.
    • (2001) Adv. Drug Del. Rev. , vol.52 , pp. 145-150
    • Borchard, G.1
  • 11
    • 0031550212 scopus 로고    scopus 로고
    • Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers
    • Calvo, P., Remunan, C., Jato, J. L. V., and Alonso, M. J. 1997. Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers. J. Appl. Polym. Sci. 63:125-132.
    • (1997) J. Appl. Polym. Sci. , vol.63 , pp. 125-132
    • Calvo, P.1    Remunan, C.2    Jato, J.L.V.3    Alonso, M.J.4
  • 13
    • 0004472732 scopus 로고    scopus 로고
    • Evaluation of biological properties of soluble chitosan and chitosan microspheres
    • Carreno, B. G., and Duncan, R. 1997. Evaluation of biological properties of soluble chitosan and chitosan microspheres. Intl. J. Pharm. 148:231-240.
    • (1997) Intl. J. Pharm. , vol.148 , pp. 231-240
    • Carreno, B.G.1    Duncan, R.2
  • 14
    • 0026483412 scopus 로고
    • Chitosan beads and granules for oral sustained delivery of nifedipine: In vitro studies
    • Chandy, T., and Sharma, C. P. 1992. Chitosan beads and granules for oral sustained delivery of nifedipine: in vitro studies. Biomaterials 13:949-952.
    • (1992) Biomaterials , vol.13 , pp. 949-952
    • Chandy, T.1    Sharma, C.P.2
  • 15
    • 0027496885 scopus 로고
    • Chitosan matrix for oral sustained delivery of ampicillin
    • Chandy, T., and Sharma, C. P. 1993. Chitosan matrix for oral sustained delivery of ampicillin. Biomaterials 14:939-944.
    • (1993) Biomaterials , vol.14 , pp. 939-944
    • Chandy, T.1    Sharma, C.P.2
  • 16
    • 0023325059 scopus 로고
    • Inhibition of platelet adhesion to glow discharge modified surfaces
    • Chandy, T., and Sharma, C. P., Sunny, M. C. 1987. Inhibition of platelet adhesion to glow discharge modified surfaces. J. Biomat. Appln. 1:533-552.
    • (1987) J. Biomat. Appln. , vol.1 , pp. 533-552
    • Chandy, T.1    Sharma, C.P.2    Sunny, M.C.3
  • 17
    • 0037032435 scopus 로고    scopus 로고
    • Effect of chitosan on in vitro release and ocular delivery of ofloxacin from erodible inserts based on poly(ethylene oxide)
    • Colo, G. D., Zambito, Y., Burgalassi, S., Serafini, A., and Saettone, M. F. 2002. Effect of chitosan on in vitro release and ocular delivery of ofloxacin from erodible inserts based on poly(ethylene oxide). Intl. J. Pharm. 248:115-122.
    • (2002) Intl. J. Pharm. , vol.248 , pp. 115-122
    • Colo, G.D.1    Zambito, Y.2    Burgalassi, S.3    Serafini, A.4    Saettone, M.F.5
  • 18
    • 0027684049 scopus 로고
    • Synthesis of N-(aminoalkyl) chitosan for microcapsules
    • Dunn, E. J., Zang, X., Sun, D., and Goosen, M. F. A. 1993. Synthesis of N-(aminoalkyl) chitosan for microcapsules. J.Appl. Polym. Sci. 50:353-365.
    • (1993) J. Appl. Polym. Sci. , vol.50 , pp. 353-365
    • Dunn, E.J.1    Zang, X.2    Sun, D.3    Goosen, M.F.A.4
  • 19
    • 43949166904 scopus 로고
    • Stabilization by chitosan of soybean oil emultion coated with phospholipids and glycocholic acid
    • Faldt, P., Bergenstahl, B., and Claesson, P. M. 1993. Stabilization by chitosan of soybean oil emultion coated with phospholipids and glycocholic acid. Coll. Surf. 71:187-195.
    • (1993) Coll. Surf. , vol.71 , pp. 187-195
    • Faldt, P.1    Bergenstahl, B.2    Claesson, P.M.3
  • 20
    • 0141719284 scopus 로고    scopus 로고
    • Enhancement of nasal absorption of insulin using chitosan nanopartilces
    • Fernandez, R. U., Calvo, P., Jato, J. R. V., and Alonso, M. J. 1999. Enhancement of nasal absorption of insulin using chitosan nanopartilces. Pharm. Res. 16:1576-1581.
    • (1999) Pharm. Res. , vol.16 , pp. 1576-1581
    • Fernandez, R.U.1    Calvo, P.2    Jato, J.R.V.3    Alonso, M.J.4
  • 21
    • 0033300109 scopus 로고    scopus 로고
    • Development of a freeze-dried formulation of insulin loaded chitosan nanoparticles intended for nasal administration
    • Fernandez, R. U., Romani, D., Calvo, P., Jato, J. R. V., and Alonso, M. J. 1999a. Development of a freeze-dried formulation of insulin loaded chitosan nanoparticles intended for nasal administration. STP Pharm. Sci. 9:429-436.
    • (1999) STP Pharm. Sci. , vol.9 , pp. 429-436
    • Fernandez, R.U.1    Romani, D.2    Calvo, P.3    Jato, J.R.V.4    Alonso, M.J.5
  • 23
    • 0037151326 scopus 로고    scopus 로고
    • Thermosensitive chitosan based hydrogel containing liposomes for the delivery of hydrophilic molecules
    • Gariepy, E. R., Leclair, G., Hildgen, P., Gupta, A., and Loroux, J. C. 2002. Thermosensitive chitosan based hydrogel containing liposomes for the delivery of hydrophilic molecules. J. Control. Rel. 82:373-383.
    • (2002) J. Control. Rel. , vol.82 , pp. 373-383
    • Gariepy, E.R.1    Leclair, G.2    Hildgen, P.3    Gupta, A.4    Loroux, J.C.5
  • 24
    • 0032121256 scopus 로고    scopus 로고
    • Influence of glutaraldehyde on drug release and mucoadhesive properties of chitosan microspheres
    • Genta, I., Costantini, M., Asti, A., Conti, B., and Montanari, L. 2000. Influence of glutaraldehyde on drug release and mucoadhesive properties of chitosan microspheres, Carbohydrate Polym. 36:81-88.
    • (2000) Carbohydrate Polym. , vol.36 , pp. 81-88
    • Genta, I.1    Costantini, M.2    Asti, A.3    Conti, B.4    Montanari, L.5
  • 26
    • 0000049862 scopus 로고    scopus 로고
    • Structural changes and release characteristics of cross-linked chitosan beads in response to solution pH
    • Gupta, K. C., and Ravikumar, M. N. V. 1999. Structural changes and release characteristics of cross-linked chitosan beads in response to solution pH. J. M.S. Pure and Appl.Chem. A36:827-841.
    • (1999) J. M.S. Pure and Appl. Chem. , vol.A36 , pp. 827-841
    • Gupta, K.C.1    Ravikumar, M.N.V.2
  • 27
    • 0034018067 scopus 로고    scopus 로고
    • Drug release behavior of beads and microgranules of chitosan
    • Gupta, K. C., and Ravikumar, M. N. V. 2000. Drug release behavior of beads and microgranules of chitosan. Biomaterials 21:1115-1119.
    • (2000) Biomaterials , vol.21 , pp. 1115-1119
    • Gupta, K.C.1    Ravikumar, M.N.V.2
  • 28
    • 0039337020 scopus 로고    scopus 로고
    • Preparation, characterization and release profiles of pH-sensitive chitosan beads
    • Gupta, K. C., and Ravikumar, M. N. V. 2000a. Preparation, characterization and release profiles of pH-sensitive chitosan beads. Polym. Intl. 49:141-146.
    • (2000) Polym. Intl. , vol.49 , pp. 141-146
    • Gupta, K.C.1    Ravikumar, M.N.V.2
  • 29
    • 0033872401 scopus 로고    scopus 로고
    • Semi-interpenetrating polymer network beads of cross-linked chitosan-glycine for controlled release of chlorphenramine maleate
    • Gupta, K. C., and Ravikumar, M. N. V. 2000b. Semi-interpenetrating polymer network beads of cross-linked chitosan-glycine for controlled release of chlorphenramine maleate. J. Appl. Polym. Sci. 76:672-683.
    • (2000) J. Appl. Polym. Sci. , vol.76 , pp. 672-683
    • Gupta, K.C.1    Ravikumar, M.N.V.2
  • 30
    • 0025956486 scopus 로고
    • Protease immobilization onto porous chitosan beads
    • Hayashi, T., and Ikada. Y. 1991. Protease immobilization onto porous chitosan beads. J. Appl. Polym. Sci. 42:85-92.
    • (1991) J. Appl. Polym. Sci. , vol.42 , pp. 85-92
    • Hayashi, T.1    Ikada, Y.2
  • 31
    • 0037472115 scopus 로고    scopus 로고
    • Chitosan-based gastrointestinal delivery systems
    • Hejazi, R., and Amiji, M. 2003. Chitosan-based gastrointestinal delivery systems. J. Control. Rel. 89:151-165.
    • (2003) J. Control. Rel. , vol.89 , pp. 151-165
    • Hejazi, R.1    Amiji, M.2
  • 32
    • 0028045021 scopus 로고
    • Interactions between liposomes and chitosan
    • Henriksen, I., Smistad, G., and Karlsen, J. 1994. Interactions between liposomes and chitosan. Intl. J. Pharm. 101:227-236.
    • (1994) Intl. J. Pharm. , vol.101 , pp. 227-236
    • Henriksen, I.1    Smistad, G.2    Karlsen, J.3
  • 33
    • 0000900281 scopus 로고
    • A biocompatible material for oral and intravenous administration
    • ed, C. G. Gebelein and R. L. Dunn. New York: Plenum Press
    • Hirano, H., Seino, H., Akiyama, I., and Nonaka, I. 1990. A biocompatible material for oral and intravenous administration. In Chitosan, ed, C. G. Gebelein and R. L. Dunn, 283-289. New York: Plenum Press.
    • (1990) Chitosan , pp. 283-289
    • Hirano, H.1    Seino, H.2    Akiyama, I.3    Nonaka, I.4
  • 34
    • 0024144884 scopus 로고
    • Biocompatibility of chitosan by oral and intravenous administration
    • Hirano, S., Seino, H., Akiyama, I., and Nonaka, I. 1989. Biocompatibility of chitosan by oral and intravenous administration. Polym. Eng. Sci. 59:897-901.
    • (1989) Polym. Eng. Sci. , vol.59 , pp. 897-901
    • Hirano, S.1    Seino, H.2    Akiyama, I.3    Nonaka, I.4
  • 35
    • 0026173933 scopus 로고
    • 10 alkyl glycosides branches: A temperature induced gelling polysaccharide
    • 10 alkyl glycosides branches: A temperature induced gelling polysaccharide. Macromolecules 24:3828-3833.
    • (1991) Macromolecules , vol.24 , pp. 3828-3833
    • Holme, K.1    Hall, L.2
  • 36
    • 0037334622 scopus 로고    scopus 로고
    • In vitro evaluation of the viscoelastic properties of chitosan-thioglycolic acid conjugates
    • Hornof, M. D., Kast, C. E., and Schnurch, A. B. 2003. In vitro evaluation of the viscoelastic properties of chitosan-thioglycolic acid conjugates. Euro. J. Pharm. and Biopharm. 55:185-190.
    • (2003) Euro. J. Pharm. and Biopharm. , vol.55 , pp. 185-190
    • Hornof, M.D.1    Kast, C.E.2    Schnurch, A.B.3
  • 37
    • 0035999699 scopus 로고    scopus 로고
    • Synthesis and characterization of chitosan-poly (acrylic acid) nanoparticles
    • Hu, Y., Jiang, X., Ding, Y., Ge, H., Yuan, Y., and Yang, C. 2002. Synthesis and characterization of chitosan-poly (acrylic acid) nanoparticles. Biomaterials 23:3193-3201.
    • (2002) Biomaterials , vol.23 , pp. 3193-3201
    • Hu, Y.1    Jiang, X.2    Ding, Y.3    Ge, H.4    Yuan, Y.5    Yang, C.6
  • 38
    • 0016627287 scopus 로고
    • The complex carbohydrates of mammalian cell surfaces and their biological roles
    • Hughes, R. C. 1975. The complex carbohydrates of mammalian cell surfaces and their biological roles. Essays Biochem. 11:1-36.
    • (1975) Essays Biochem. , vol.11 , pp. 1-36
    • Hughes, R.C.1
  • 39
    • 0030294928 scopus 로고    scopus 로고
    • Calcium alginate beads coated with chitosan, effect of structure encapsulated materials on their release
    • Huguet, M. L., and Dellacherie, E. 1996. Calcium alginate beads coated with chitosan, effect of structure encapsulated materials on their release. Process Biochem. 31:745-751.
    • (1996) Process Biochem. , vol.31 , pp. 745-751
    • Huguet, M.L.1    Dellacherie, E.2
  • 41
    • 0030019344 scopus 로고    scopus 로고
    • Calcium alginate beads coated with polycationic polymers: Comparison of chitosan and DEAE-dextran
    • Huguet, M. L., Neufeld, R. J., and Dellacherie, E. 1996a. Calcium alginate beads coated with polycationic polymers: comparison of chitosan and DEAE-dextran. Process Biochem. 31:347-353.
    • (1996) Process Biochem. , vol.31 , pp. 347-353
    • Huguet, M.L.1    Neufeld, R.J.2    Dellacherie, E.3
  • 42
    • 0032121256 scopus 로고    scopus 로고
    • Influence of glutaraldehyde on drug release and mucoadhesive properties of chitosan microspheres
    • Ida, G., Monica, C., Annalia, A., Bice, C., and Luisa, M. 1998. Influence of glutaraldehyde on drug release and mucoadhesive properties of chitosan microspheres. Carbohydrate Polym. 36:81-88.
    • (1998) Carbohydrate Polym. , vol.36 , pp. 81-88
    • Ida, G.1    Monica, C.2    Annalia, A.3    Bice, C.4    Luisa, M.5
  • 43
    • 0031783879 scopus 로고    scopus 로고
    • Chitosan and its use as a pharmaceutical excipient
    • Ilium, L. 1998. Chitosan and its use as a pharmaceutical excipient. Pharm. Res. 15:1326-1331.
    • (1998) Pharm. Res. , vol.15 , pp. 1326-1331
    • Ilium, L.1
  • 44
    • 0028124642 scopus 로고
    • Chitosan as a novel nasal delivery system for peptide drugs
    • Ilium, L., Farraj, N. F., and Davis, S. S. 1994. Chitosan as a novel nasal delivery system for peptide drugs. Pharm. Res. 11:1186-1189.
    • (1994) Pharm. Res. , vol.11 , pp. 1186-1189
    • Ilium, L.1    Farraj, N.F.2    Davis, S.S.3
  • 45
    • 0035937593 scopus 로고    scopus 로고
    • Polysaccharide colloidal partilce as delivery systems for macromolecules
    • Janes, K. A., Calvo, P., and Alonso, M. J. 2001. Polysaccharide colloidal partilce as delivery systems for macromolecules. Adv. Drug Deliv. Rev. 47:83-97.
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 83-97
    • Janes, K.A.1    Calvo, P.2    Alonso, M.J.3
  • 48
    • 0034925740 scopus 로고    scopus 로고
    • Thiolated polymers-thiomers, development and in vitro evaluation of chitosan-thioglycolic acid conjugates
    • Kast, C. E., and Schnurch, A. B. 2001. Thiolated polymers-thiomers, development and in vitro evaluation of chitosan-thioglycolic acid conjugates. Biomaterials 22:2345-2352.
    • (2001) Biomaterials , vol.22 , pp. 2345-2352
    • Kast, C.E.1    Schnurch, A.B.2
  • 49
    • 0034026119 scopus 로고    scopus 로고
    • A novel water-soluble N-succinyl chitosan-mitomycin C conjugate prepared by direct carbodiimide coupling: Physicochemical properties, antitumor characteristics and systemic retention
    • Kato, Y., Onishi, H., and Machida, M. 2000. A novel water-soluble N-succinyl chitosan-mitomycin C conjugate prepared by direct carbodiimide coupling: physicochemical properties, antitumor characteristics and systemic retention. STP Pharm. Sci. 10:133-142.
    • (2000) STP Pharm. Sci. , vol.10 , pp. 133-142
    • Kato, Y.1    Onishi, H.2    Machida, M.3
  • 50
    • 0038946003 scopus 로고    scopus 로고
    • Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria
    • Kernels, S., Bogdanova, A., Kraehenbuhl, J. P., and Pringault, E. 1997. Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria. Science 277:949-952.
    • (1997) Science , vol.277 , pp. 949-952
    • Kernels, S.1    Bogdanova, A.2    Kraehenbuhl, J.P.3    Pringault, E.4
  • 52
    • 0347390692 scopus 로고    scopus 로고
    • Chitin enzymology-chitinase
    • Koga, D. 1998. Chitin enzymology-chitinase. Adv. Chitin Sci. 3:16-23.
    • (1998) Adv. Chitin Sci. , vol.3 , pp. 16-23
    • Koga, D.1
  • 53
    • 0001099485 scopus 로고
    • Saccharide sensitive phase transition of a lectin-loaded gel
    • Kokufuta, E., Zhang, Y. Q., and Tanaka, T. 1991. Saccharide sensitive phase transition of a lectin-loaded gel. Nature 351:302-304.
    • (1991) Nature , vol.351 , pp. 302-304
    • Kokufuta, E.1    Zhang, Y.Q.2    Tanaka, T.3
  • 54
    • 0001735013 scopus 로고
    • Permeability of membranes containing ionogenic group
    • Kopecek, J., Vacik, J., and Lim, D. 1971. Permeability of membranes containing ionogenic group. J. Polym. Sci. 9:2801-2815.
    • (1971) J. Polym. Sci. , vol.9 , pp. 2801-2815
    • Kopecek, J.1    Vacik, J.2    Lim, D.3
  • 55
    • 0001133755 scopus 로고    scopus 로고
    • Modulated degradation of hydrogels with thermo-responsive network in relation to their swelling behavior
    • Kurisawa, M., Matsuo, Y., and Yui, N. 1998. Modulated degradation of hydrogels with thermo-responsive network in relation to their swelling behavior. Macromol Chem. Phys. 199:705-709.
    • (1998) Macromol Chem. Phys. , vol.199 , pp. 705-709
    • Kurisawa, M.1    Matsuo, Y.2    Yui, N.3
  • 56
    • 0032509928 scopus 로고    scopus 로고
    • Preparation of chitosan self-aggregates as a gene delivery system
    • Lee, K. Y., Kwon, I. C., Kim, Y. H., Jo, W. H., and Jeong, S. Y. 1998. Preparation of chitosan self-aggregates as a gene delivery system. J. Control. Rel. 51:213-220.
    • (1998) J. Control. Rel. , vol.51 , pp. 213-220
    • Lee, K.Y.1    Kwon, I.C.2    Kim, Y.H.3    Jo, W.H.4    Jeong, S.Y.5
  • 57
    • 0030677716 scopus 로고    scopus 로고
    • Polyelectrolyte complexes of sodium alginate with chitosan or its derivatives
    • Lee, K. Y., Park, W. H., and Ha, W. S. 1997. Polyelectrolyte complexes of sodium alginate with chitosan or its derivatives. J. Appl. Polym. Sci. 63:425-432.
    • (1997) J. Appl. Polym. Sci. , vol.63 , pp. 425-432
    • Lee, K.Y.1    Park, W.H.2    Ha, W.S.3
  • 58
    • 0026262303 scopus 로고
    • Pervaporation separation of water-ethanol through modified chitosan membranes. IV. Phosphorylated chitosan membranes
    • Lee, Y. M., and Shin, E. M. 1991. Pervaporation separation of water-ethanol through modified chitosan membranes, IV. Phosphorylated chitosan membranes. J. Membrane Sci. 64:145-152.
    • (1991) J. Membrane Sci. , vol.64 , pp. 145-152
    • Lee, Y.M.1    Shin, E.M.2
  • 59
    • 0026800237 scopus 로고
    • In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers
    • Lehr, C. M., Bowstra, J. A., Schacht, E. H., and Jungiger, H. E. 1992. In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Intl. J. Pharm. 78:43-48.
    • (1992) Intl. J. Pharm. , vol.78 , pp. 43-48
    • Lehr, C.M.1    Bowstra, J.A.2    Schacht, E.H.3    Jungiger, H.E.4
  • 61
    • 0032473392 scopus 로고    scopus 로고
    • Design of microencapsulated chitosan microspheres for colonic drug delivery
    • Lorenzo, M. L., Remunan, C. L., Jato, J. L. V., and Alonso, M. J. 1998. Design of microencapsulated chitosan microspheres for colonic drug delivery. J. Control. Rel. 52:109-118.
    • (1998) J. Control. Rel. , vol.52 , pp. 109-118
    • Lorenzo, M.L.1    Remunan, C.L.2    Jato, J.L.V.3    Alonso, M.J.4
  • 63
    • 0030453145 scopus 로고    scopus 로고
    • Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide buserelin in vivo
    • Lueben, H. L., Leeuw, B. J. D., Langemeyer, B. W., Boer, A. G. D., Verhoef, J. C., and Junginger, H. E. 1996. Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide buserelin in vivo. Pharm. Res. 13:1668-1672.
    • (1996) Pharm. Res. , vol.13 , pp. 1668-1672
    • Lueben, H.L.1    Leeuw, B.J.D.2    Langemeyer, B.W.3    Boer, A.G.D.4    Verhoef, J.C.5    Junginger, H.E.6
  • 66
    • 0037161322 scopus 로고    scopus 로고
    • The release of model macromolecules controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels
    • Martin, L., Wilson, C. G., Koosha, F., Tetley, L., Gray, A. I., Senel, S., and Uchegbu, I. F. 2002. The release of model macromolecules controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels. J. Control. Rel. 80:87-91.
    • (2002) J. Control. Rel. , vol.80 , pp. 87-91
    • Martin, L.1    Wilson, C.G.2    Koosha, F.3    Tetley, L.4    Gray, A.I.5    Senel, S.6    Uchegbu, I.F.7
  • 67
    • 0033197952 scopus 로고    scopus 로고
    • Porous chitosan microsphere for controlling the antigen release of Newcastle disease vaccine: Preparation of antigen-adsorbed microsphere and in vitro release
    • Mi, F. L., Shyu, S. S., Chen, C. T., and Schoung, J. Y. 1999. Porous chitosan microsphere for controlling the antigen release of Newcastle disease vaccine: preparation of antigen-adsorbed microsphere and in vitro release. Biomaterials 20:1603-1612.
    • (1999) Biomaterials , vol.20 , pp. 1603-1612
    • Mi, F.L.1    Shyu, S.S.2    Chen, C.T.3    Schoung, J.Y.4
  • 68
    • 0034249313 scopus 로고    scopus 로고
    • Synthesis and characterization of a novel chitosan based network prepared using naturally occuring crosslinker
    • Mi, F. L., Sung, H. W., and Shyu, S. S. 2000. Synthesis and characterization of a novel chitosan based network prepared using naturally occuring crosslinker. J. Polym. Sci. Part A: Polym. Chem. 38:2804-2814.
    • (2000) J. Polym. Sci. Part A: Polym. Chem. , vol.38 , pp. 2804-2814
    • Mi, F.L.1    Sung, H.W.2    Shyu, S.S.3
  • 69
    • 0036027616 scopus 로고    scopus 로고
    • In vivo biocompatibility and degradability of a novel injectable-chitosan-based implant
    • Mi, F. L., Tan, Y. C., Liang, H. F., and Sung, H. W. 2002. In vivo biocompatibility and degradability of a novel injectable-chitosan-based implant. Biomaterials 23:181-191.
    • (2002) Biomaterials , vol.23 , pp. 181-191
    • Mi, F.L.1    Tan, Y.C.2    Liang, H.F.3    Sung, H.W.4
  • 72
    • 0031071758 scopus 로고    scopus 로고
    • Design of quaternary chitosan conjugate having antennary galactose residues as a gene delivery tool
    • Murata, J., Ohya, Y., and Ouchi, T. 1997. Design of quaternary chitosan conjugate having antennary galactose residues as a gene delivery tool. Carbohydrate Polymers 32:105-109.
    • (1997) Carbohydrate Polymers , vol.32 , pp. 105-109
    • Murata, J.1    Ohya, Y.2    Ouchi, T.3
  • 73
    • 0003530246 scopus 로고
    • Natural chelating polymers
    • ed. R. Muzzarelli. Oxford: Pergamon Press
    • Muzzarelli, R. 1973. Natural chelating polymers. In Chitosan, ed. R. Muzzarelli, 144-176. Oxford: Pergamon Press.
    • (1973) Chitosan , pp. 144-176
    • Muzzarelli, R.1
  • 74
    • 0030748702 scopus 로고    scopus 로고
    • Human enzymatic activities related to the therapeutic administration of chitin derivatives
    • Muzzarelli, R. A. A. 1997. Human enzymatic activities related to the therapeutic administration of chitin derivatives. Cell Mol. Life Sci. 53:131-140.
    • (1997) Cell Mol. Life Sci. , vol.53 , pp. 131-140
    • Muzzarelli, R.A.A.1
  • 75
    • 0022816347 scopus 로고
    • Macrophage activation with multiporous beads prepared from partially deacetylated chitin
    • Nishimura, K., Nishimura, S., Seo, H., Nishi, N., Tokura, S., and Azuma, I. 1986. Macrophage activation with multiporous beads prepared from partially deacetylated chitin. J. Biomed. Mater. Res. 20:1359-1372.
    • (1986) J. Biomed. Mater. Res. , vol.20 , pp. 1359-1372
    • Nishimura, K.1    Nishimura, S.2    Seo, H.3    Nishi, N.4    Tokura, S.5    Azuma, I.6
  • 76
    • 0001935221 scopus 로고
    • An efficient method for the synthesis of novel amphiphilic polysaccharide by region and thermo selective modifications of chitosan
    • Nishimura, S., Miyura, Y., Ren, L., Sato, M., Yamagishi, A., Nishi, N., Tokura, S., Kurita, K., and Ishii, S. 1993. An efficient method for the synthesis of novel amphiphilic polysaccharide by region and thermo selective modifications of chitosan. Chemistry letters 1623-1626.
    • (1993) Chemistry Letters , pp. 1623-1626
    • Nishimura, S.1    Miyura, Y.2    Ren, L.3    Sato, M.4    Yamagishi, A.5    Nishi, N.6    Tokura, S.7    Kurita, K.8    Ishii, S.9
  • 77
    • 0027986222 scopus 로고
    • Release behavior of 5-fluorouracil from chitosan-gel nanospheres immobilizing 5-fluorouracil coated with polysaccharides and their cell specific cytotoxicity
    • Ohya, Y., Shiratani, M., Kobayashi, H., and Ouchi, T. 1994. Release behavior of 5-fluorouracil from chitosan-gel nanospheres immobilizing 5-fluorouracil coated with polysaccharides and their cell specific cytotoxicity. Pure Appl. Chem. A31:629-642.
    • (1994) Pure Appl. Chem. , vol.A31 , pp. 629-642
    • Ohya, Y.1    Shiratani, M.2    Kobayashi, H.3    Ouchi, T.4
  • 79
    • 0002907719 scopus 로고
    • Chitin and chitosan sources, chemistry, biochemistry, physical properties and applications
    • ed. G. S. Braek, T. Antonsen, and P. Sandford. London: Elsevier
    • Olson, R., Schwartzmiller, D., Weppner, W., and Winandy, R. 1988. Chitin and chitosan sources, chemistry, biochemistry, physical properties and applications. In Biomedical Application of Chitin and its Derivatives, ed. G. S. Braek, T. Antonsen, and P. Sandford, 813-828. London: Elsevier.
    • (1988) Biomedical Application of Chitin and Its Derivatives , pp. 813-828
    • Olson, R.1    Schwartzmiller, D.2    Weppner, W.3    Winandy, R.4
  • 81
    • 0242626283 scopus 로고
    • Macromolecular prodrugs of cytarabine and mitomycin C with chitosan, N-succinyl chitosan and 6-O-carboxymethyl-chitin as drug carriers
    • ed. L. S. Karnicki, M. M. Brzeski, P. J. Bykowski, and A. P. Wojtasz. Wirtchaftsverlag NW: Bremerhaven
    • Onishi, H., Takahashi, H., Yoshiyasu, M., Machida, Y., and Nagai, T. 1994. Macromolecular prodrugs of cytarabine and mitomycin C with chitosan, N-succinyl chitosan and 6-O-carboxymethyl-chitin as drug carriers. In Chitin World, ed. L. S. Karnicki, M. M. Brzeski, P. J. Bykowski, and A. P. Wojtasz, 301-310. Wirtchaftsverlag NW: Bremerhaven.
    • (1994) Chitin World , pp. 301-310
    • Onishi, H.1    Takahashi, H.2    Yoshiyasu, M.3    Machida, Y.4    Nagai, T.5
  • 82
    • 0035152497 scopus 로고    scopus 로고
    • Preparation and in vitro properties of N-succinyl chitosan or carboxyl methyl chitin-mitomycin C conjugates microparticles with specified size
    • Onishi, H., Takahashi, T., Yoshiyasu, M., and Machida, Y. 2001. Preparation and in vitro properties of N-succinyl chitosan or carboxyl methyl chitin-mitomycin C conjugates microparticles with specified size. Drug. Dev. Ind. Pharm. 27:659-667.
    • (2001) Drug. Dev. Ind. Pharm. , vol.27 , pp. 659-667
    • Onishi, H.1    Takahashi, T.2    Yoshiyasu, M.3    Machida, Y.4
  • 86
    • 0035126943 scopus 로고    scopus 로고
    • Polymeric controlled drug delivery systems: Perspective issues and opportunities
    • Ravikumar, M. N. V., and Kumar, N. 2001. Polymeric controlled drug delivery systems: perspective issues and opportunities. Drug Devel. Ind. Pharm. 27:1-18.
    • (2001) Drug Devel. Ind. Pharm. , vol.27 , pp. 1-18
    • Ravikumar, M.N.V.1    Kumar, N.2
  • 87
    • 0347985635 scopus 로고    scopus 로고
    • Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: Synthesis and in vitro evaluation
    • Roldo, M., Hornof, M., Caliceti, P., and Schnurch, A. B. 2004. Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: synthesis and in vitro evaluation. Euro. J. Pharm. Biopharm. 57:115-121.
    • (2004) Euro. J. Pharm. Biopharm. , vol.57 , pp. 115-121
    • Roldo, M.1    Hornof, M.2    Caliceti, P.3    Schnurch, A.B.4
  • 88
    • 0032958073 scopus 로고    scopus 로고
    • Oral gene delivery with chitosan-DNA nanopartilces generates immunologic protection in a murine model of peanut allergy
    • Roy, K., Mao, H. Q., Huang, S. K., and Leong, K. W. 1999. Oral gene delivery with chitosan-DNA nanopartilces generates immunologic protection in a murine model of peanut allergy. Nature Med. 5:387-391.
    • (1999) Nature Med. , vol.5 , pp. 387-391
    • Roy, K.1    Mao, H.Q.2    Huang, S.K.3    Leong, K.W.4
  • 90
    • 0029918365 scopus 로고    scopus 로고
    • Preparation and drug release characteristics of the conjugates of mitomycin C with glycol-chitosan and n-succinyl chitosan
    • Sato, M., Onishi, H., Machida, M., and Nagai, T. 1996. Preparation and drug release characteristics of the conjugates of mitomycin C with glycol-chitosan and n-succinyl chitosan. Biol. Pharm. Bull. 19:241-245.
    • (1996) Biol. Pharm. Bull. , vol.19 , pp. 241-245
    • Sato, M.1    Onishi, H.2    Machida, M.3    Nagai, T.4
  • 91
    • 0029827379 scopus 로고    scopus 로고
    • In vivo drug release and antitumor characteristics of water-soluble conjugates of mitomycin C with glycol-chitosan and N-succinyl-chitosan
    • Sato, M., Onishi, H., Takahara, J., Machida, Y., and Nagai, T. 1996a. In vivo drug release and antitumor characteristics of water-soluble conjugates of mitomycin C with glycol-chitosan and N-succinyl-chitosan. Biol. Pharm. Bull. 19:1170-1177.
    • (1996) Biol. Pharm. Bull. , vol.19 , pp. 1170-1177
    • Sato, M.1    Onishi, H.2    Takahara, J.3    Machida, Y.4    Nagai, T.5
  • 92
    • 0030355604 scopus 로고    scopus 로고
    • Formation of a DNA/polygalactosamine complex and its interaction with cells
    • Sato, T., Shirakawa, N., Nishi, H., and Okahata, Y. 1996b. Formation of a DNA/polygalactosamine complex and its interaction with cells. Chem. Lett. 9:725-726.
    • (1996) Chem. Lett. , vol.9 , pp. 725-726
    • Sato, T.1    Shirakawa, N.2    Nishi, H.3    Okahata, Y.4
  • 93
    • 0030787377 scopus 로고    scopus 로고
    • Chitosan as absorption enhancers for poorly absorbable drugs. 2. Mechanism of absorption enhancement
    • Schipper, N. G. M., Hoogstraate, J. A., Boer, A. G. D., Varum, K. M., and Artursson, P. 1997. Chitosan as absorption enhancers for poorly absorbable drugs. 2. Mechanism of absorption enhancement. Pharm. Res. 14:923-929.
    • (1997) Pharm. Res. , vol.14 , pp. 923-929
    • Schipper, N.G.M.1    Hoogstraate, J.A.2    Boer, A.G.D.3    Varum, K.M.4    Artursson, P.5
  • 94
    • 0346735298 scopus 로고    scopus 로고
    • Thiolated chitosans: Development and in vitro evaluation of a mucoadhesive, permeation enhancing oral drug delivery system
    • Schnurch, A. B., Guggi, D., and Pinter, Y. 2004. Thiolated chitosans: development and in vitro evaluation of a mucoadhesive, permeation enhancing oral drug delivery system. J. Control. Rel. 94:177-186.
    • (2004) J. Control. Rel. , vol.94 , pp. 177-186
    • Schnurch, A.B.1    Guggi, D.2    Pinter, Y.3
  • 95
    • 0038460837 scopus 로고    scopus 로고
    • Thiolated polymers-thiomers: Synthesis and in vitro evaluation of chitosan-2-iminothiolane conjugates
    • Schnurch, A. B., Hornof, M., and Zoidl, T. 2003. Thiolated polymers-thiomers: synthesis and in vitro evaluation of chitosan-2-iminothiolane conjugates. Intl. J. Pharm. 260:229-237.
    • (2003) Intl. J. Pharm. , vol.260 , pp. 229-237
    • Schnurch, A.B.1    Hornof, M.2    Zoidl, T.3
  • 96
    • 0034633894 scopus 로고    scopus 로고
    • Preparation and in vitro evaluation of poly(N-vinyl-2-pyrrolidone- polyethylene glycol diacrylate)-chitosan interpolymeric pH-responsive hydrogels for oral drug delivery
    • Shantha, K. L., and Harding, D. R. K. 2000. Preparation and in vitro evaluation of poly(N-vinyl-2-pyrrolidone-polyethylene glycol diacrylate)-chitosan interpolymeric pH-responsive hydrogels for oral drug delivery. Intl. J. Pharm. 207:65-70.
    • (2000) Intl. J. Pharm. , vol.207 , pp. 65-70
    • Shantha, K.L.1    Harding, D.R.K.2
  • 97
    • 33947463859 scopus 로고
    • The use of water-soluble and basic carbodiimides in peptide synthesis
    • Sheehan, J. C., and Hlavka, J. J. 1956. The use of water-soluble and basic carbodiimides in peptide synthesis. J. Org. Chem. 21:439-441.
    • (1956) J. Org. Chem. , vol.21 , pp. 439-441
    • Sheehan, J.C.1    Hlavka, J.J.2
  • 98
    • 11244282809 scopus 로고
    • Mitomycin basic studies
    • ed. T. Taguchi. Tokyo: Kyowa Kikaku Tsushin
    • Shirahata, K. 1984. Mitomycin basic studies. In Derivatives and Activities, ed. T. Taguchi, 25-43. Tokyo: Kyowa Kikaku Tsushin.
    • (1984) Derivatives and Activities , pp. 25-43
    • Shirahata, K.1
  • 99
    • 1842843556 scopus 로고    scopus 로고
    • The influence of multivalent phosphate structure on the properties of ionically cross-linked chitosan films for controlled drug release
    • Shu, X. Z., and Zhu, K. J. 2002. The influence of multivalent phosphate structure on the properties of ionically cross-linked chitosan films for controlled drug release, Euro. J. Pharm. Biopharm. 54:235-243.
    • (2002) Euro. J. Pharm. Biopharm. , vol.54 , pp. 235-243
    • Shu, X.Z.1    Zhu, K.J.2
  • 101
    • 0026479961 scopus 로고
    • Synthesis and drug release characteristics of the conjugates of mitomycin C with N-succinyl-chitosan and carboxymethy-chitin
    • Song, Y., Onishi, H., and Machida, Y. 1992. Synthesis and drug release characteristics of the conjugates of mitomycin C with N-succinyl-chitosan and carboxymethy-chitin. Chem. Pharm. Bull. 40:2822-2825.
    • (1992) Chem. Pharm. Bull. , vol.40 , pp. 2822-2825
    • Song, Y.1    Onishi, H.2    Machida, Y.3
  • 102
    • 0028954956 scopus 로고
    • Particle characteristics of carboxymethyl chitin-mitomycin C conjugate and their distribution and histological effect on some tissues after intravenous administration
    • Song, Y., Onishi, H., Machida, Y., and Nagai, T. 1995. Particle characteristics of carboxymethyl chitin-mitomycin C conjugate and their distribution and histological effect on some tissues after intravenous administration. STP Pharm. Sci. 5:162-170.
    • (1995) STP Pharm. Sci. , vol.5 , pp. 162-170
    • Song, Y.1    Onishi, H.2    Machida, Y.3    Nagai, T.4
  • 103
    • 0030272522 scopus 로고    scopus 로고
    • Drug release and antitumor characteristics of N-succinyl chitosan-mitomycin C as an implant
    • Song, Y., Onishi, H., Machida, Y., and Nagai, T. 1996. Drug release and antitumor characteristics of N-succinyl chitosan-mitomycin C as an implant. J. Control. Rel. 42:93-100.
    • (1996) J. Control. Rel. , vol.42 , pp. 93-100
    • Song, Y.1    Onishi, H.2    Machida, Y.3    Nagai, T.4
  • 104
    • 0037768709 scopus 로고    scopus 로고
    • Release phenomena of insulin from an implantable device composed of a polyion complex of chitosan and sodium hyaluronate
    • Surini, S., Akiyama, H., Morishita, M., Nagai, T., and Takayama, K. 2003. Release phenomena of insulin from an implantable device composed of a polyion complex of chitosan and sodium hyaluronate. J. Control. Rel. 90:291-301.
    • (2003) J. Control. Rel. , vol.90 , pp. 291-301
    • Surini, S.1    Akiyama, H.2    Morishita, M.3    Nagai, T.4    Takayama, K.5
  • 105
    • 0025451585 scopus 로고
    • Phase transition in polymer gels induced by visible light
    • Suzuki, A., and Tanaka, T. 1990. Phase transition in polymer gels induced by visible light. Nature 346:345-347.
    • (1990) Nature , vol.346 , pp. 345-347
    • Suzuki, A.1    Tanaka, T.2
  • 106
    • 0242352525 scopus 로고    scopus 로고
    • N-acylated chitosan: Hydrophobic matrices for controlled drug release
    • Tien, C. L., Lacroix, M., Szabo, P. I., and Mateescu, M. A. 2003. N-acylated chitosan: hydrophobic matrices for controlled drug release. J.Control. Rel. 93:1-13.
    • (2003) J. Control. Rel. , vol.93 , pp. 1-13
    • Tien, C.L.1    Lacroix, M.2    Szabo, P.I.3    Mateescu, M.A.4
  • 107
    • 0031918253 scopus 로고    scopus 로고
    • Stealth PLA-PEG nanoparticles as protein carriers for nasal administration
    • Tobio, M., Gref, R., Sanchez, A., Langer, R., and Alonsa, M. J. 1998. Stealth PLA-PEG nanoparticles as protein carriers for nasal administration. Pharm. Res. 15:270-275.
    • (1998) Pharm. Res. , vol.15 , pp. 270-275
    • Tobio, M.1    Gref, R.2    Sanchez, A.3    Langer, R.4    Alonsa, M.J.5
  • 108
    • 0343962248 scopus 로고    scopus 로고
    • The role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles
    • Tobio, M., Sanchez, A., Vila, A., Soriano, I., Evora, C., and Jato, J. L. V. 2000. The role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles. Coll. Surf. Biointerf. 18:315-323.
    • (2000) Coll. Surf. Biointerf. , vol.18 , pp. 315-323
    • Tobio, M.1    Sanchez, A.2    Vila, A.3    Soriano, I.4    Evora, C.5    Jato, J.L.V.6
  • 109
    • 0242607099 scopus 로고    scopus 로고
    • Chitosan-poly(acrylic)acid polyionic complex: In vivo study to demonstrate prolonged gastric retention
    • Torrado, S., Prada, P., Torre, P. M., and Torrado, S. 2004. Chitosan-poly(acrylic)acid polyionic complex: in vivo study to demonstrate prolonged gastric retention. Biomaterials 25:917-923.
    • (2004) Biomaterials , vol.25 , pp. 917-923
    • Torrado, S.1    Prada, P.2    Torre, P.M.3    Torrado, S.4
  • 110
    • 0033582731 scopus 로고    scopus 로고
    • Colon-specific delivery of R68070, a new thromboxane synthase inhibitor, using using chitosan capsules, therapeutic effects against 2,4,6- trinitrobenzenesulfonic acid-induced ulcerative colitis in rats
    • Tozaki, H., Fujita, T., Odoriba, T., Terabe, A., Suzuki, T., Tanaka, C., Okabe, S., and Muranishi, S. 1999. Colon-specific delivery of R68070, a new thromboxane synthase inhibitor, using using chitosan capsules, therapeutic effects against 2,4,6-trinitrobenzenesulfonic acid-induced ulcerative colitis in rats. Life Sci. 64:1155-1162.
    • (1999) Life Sci. , vol.64 , pp. 1155-1162
    • Tozaki, H.1    Fujita, T.2    Odoriba, T.3    Terabe, A.4    Suzuki, T.5    Tanaka, C.6    Okabe, S.7    Muranishi, S.8
  • 111
    • 0030612306 scopus 로고    scopus 로고
    • Chitosan capsules for colon-specific drug delivery, improvement of insulin absorption from the rat colon
    • Tozaki, H., Komoike, J., Tada, C., Maruyama, T., Terabe, A., Suzuki, T., Yamamoto, A., and Muranishi, S. 1997. Chitosan capsules for colon-specific drug delivery, improvement of insulin absorption from the rat colon. J. Pharm. Sci. 86:1016-1021.
    • (1997) J. Pharm. Sci. , vol.86 , pp. 1016-1021
    • Tozaki, H.1    Komoike, J.2    Tada, C.3    Maruyama, T.4    Terabe, A.5    Suzuki, T.6    Yamamoto, A.7    Muranishi, S.8
  • 113
    • 0141719284 scopus 로고    scopus 로고
    • Enhancement of nasal absorption of insulin using chitosan nanoparticles
    • Urrusuno, R. F., Calvo, P., Lopez, C. R., Jato, J. L. V., and Alonso, M. J. 1999. Enhancement of nasal absorption of insulin using chitosan nanoparticles. Pharm. Res. 16:1576-1581.
    • (1999) Pharm. Res. , vol.16 , pp. 1576-1581
    • Urrusuno, R.F.1    Calvo, P.2    Lopez, C.R.3    Jato, J.L.V.4    Alonso, M.J.5
  • 115
    • 0028425577 scopus 로고
    • Novel silica-biopolymer nanocomposites: The silica sol-gel process in biopolymer organogels
    • Watzke, H. J., and Dieschbourg, C. 1994. Novel silica-biopolymer nanocomposites: the silica sol-gel process in biopolymer organogels. Adv. Coll. Interfac. Sci. 50:1-14.
    • (1994) Adv. Coll. Interfac. Sci. , vol.50 , pp. 1-14
    • Watzke, H.J.1    Dieschbourg, C.2
  • 116
    • 0002848709 scopus 로고
    • An overview of the regulatory status and of the safety of chitin and chitosan as food and pharmaceutical ingredients
    • ed. C. J. Brine, P. A. Sanford, and J. P. Zikakis. London: Elsevier
    • Weiner, M. L. 1992. An overview of the regulatory status and of the safety of chitin and chitosan as food and pharmaceutical ingredients. In Advances in Chitin and Chitosan, ed. C. J. Brine, P. A. Sanford, and J. P. Zikakis, 670-678. London: Elsevier.
    • (1992) Advances in Chitin and Chitosan , pp. 670-678
    • Weiner, M.L.1
  • 117
    • 0031764103 scopus 로고    scopus 로고
    • Investigation of a Pmdi system containing chitosan microspheres and p134a
    • Williams, R. O., Barron, M. K., Alonso, M. J., and Remunan, C. L. 1998. Investigation of a Pmdi system containing chitosan microspheres and p134a. Intl. Pharm. 174:209-222.
    • (1998) Intl. Pharm. , vol.174 , pp. 209-222
    • Williams, R.O.1    Barron, M.K.2    Alonso, M.J.3    Remunan, C.L.4
  • 118
    • 0038381523 scopus 로고    scopus 로고
    • Formulation and characterization of pH sensitive drug carrier based on phosphorylated chitosan
    • Win, P. P., Ya, Y. S., Hong, K. J., and Kajiuchi, T. 2003. Formulation and characterization of pH sensitive drug carrier based on phosphorylated chitosan. Carbohydrate Polym. 53:305-310.
    • (2003) Carbohydrate Polym. , vol.53 , pp. 305-310
    • Win, P.P.1    Ya, Y.S.2    Hong, K.J.3    Kajiuchi, T.4
  • 119
    • 0005303733 scopus 로고
    • Preparation of partially N-succinylated chitosans and their cross-linked gels
    • Yamaguchi, R., Arai, Y., Itoh, T., and Hirano, S. 1981. Preparation of partially N-succinylated chitosans and their cross-linked gels. Carbo. Res. 15:172-175.
    • (1981) Carbo. Res. , vol.15 , pp. 172-175
    • Yamaguchi, R.1    Arai, Y.2    Itoh, T.3    Hirano, S.4
  • 120
    • 0033994494 scopus 로고    scopus 로고
    • Colon-specific delivery of peptide drugs and anti-inflammatory drugs using chitosan capsules
    • Yamamoto, A., Tozaki, H., Okada, N., and Fujita, T. 2000. Colon-specific delivery of peptide drugs and anti-inflammatory drugs using chitosan capsules. STP Pharm. Sci. 10:23-34.
    • (2000) STP Pharm. Sci. , vol.10 , pp. 23-34
    • Yamamoto, A.1    Tozaki, H.2    Okada, N.3    Fujita, T.4
  • 121
    • 0028449317 scopus 로고
    • pH-dependent hydrolysis and drug release of chitosan/polyether interpenetrating polymer network hydrogel
    • Yao, K., Peng, T., Xu, M., and Yuan, C. 1994. pH-dependent hydrolysis and drug release of chitosan/polyether interpenetrating polymer network hydrogel. Polym. Intl. 34:213-219.
    • (1994) Polym. Intl. , vol.34 , pp. 213-219
    • Yao, K.1    Peng, T.2    Xu, M.3    Yuan, C.4
  • 123
    • 0009142683 scopus 로고    scopus 로고
    • Drug release behavior of chitosan/gelatine network polymer microspheres
    • Yin, Y., Xu, M., Chen, X., and Yao, K. D. 1996. Drug release behavior of chitosan/gelatine network polymer microspheres. Chinese Sci. Bull. 41: 1266-1270.
    • (1996) Chinese Sci. Bull. , vol.41 , pp. 1266-1270
    • Yin, Y.1    Xu, M.2    Chen, X.3    Yao, K.D.4
  • 124
    • 0029382062 scopus 로고
    • Chitosan derived polymer surfactants and their micellar properties
    • Yoshioka, H., Nonaka, K., Fukada, K., and Kazama, S. 1995. Chitosan derived polymer surfactants and their micellar properties. Biosci. Biotech. Biochem. 59:1901-1904.
    • (1995) Biosci. Biotech. Biochem. , vol.59 , pp. 1901-1904
    • Yoshioka, H.1    Nonaka, K.2    Fukada, K.3    Kazama, S.4
  • 125
    • 0025297898 scopus 로고
    • Receptor-mediated endocytosis of transferring-poly cation conjugates, an efficient to introduce DNA into hematopoietic cells
    • Washington: National Academy of Sciences
    • Zenke, M., Steinlein, P., Wagner, E., Cotton, M., Beug, H., and Birnstiel, M. L. 1990. Receptor-mediated endocytosis of transferring-poly cation conjugates, an efficient to introduce DNA into hematopoietic cells. In Proceedings of the 87th National Academy of Sciences. Washington: National Academy of Sciences.
    • (1990) Proceedings of the 87th National Academy of Sciences
    • Zenke, M.1    Steinlein, P.2    Wagner, E.3    Cotton, M.4    Beug, H.5    Birnstiel, M.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.