Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs

Gene Therapy

Volumn 6, Issue 12, 1999, Pages 1995-2004

  Bragonzi, A ^a   Boletta, A ^a   Biffi, A ^a   Muggia, A ^a   Sersale, G ^b   Cheng, S H ^c   Bordignon, C ^a   Assael, B M ^b   Conese, M ^a  

^a SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c GENZYME CORPORATION   (United States)

Author keywords

Cationic polymers; DNase; Gene therapy; Intravenous delivery; Lipids; Pneumocytes

Indexed keywords

BETA GALACTOSIDE; CATION; DEUTERIUM OXIDE; LIPID; LUCIFERASE; PLASMID DNA; PLASMID VECTOR; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA ADDUCT; DNA DEGRADATION; ESCHERICHIA COLI; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HEART; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KIDNEY; LACTOSE OPERON; LIVER; LUNG; LUNG ALVEOLUS CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; RESPIRATORY TRACT INFLAMMATION; SERUM; SPLEEN; TAIL; TRANSGENE;

ANIMALS; BETA-GALACTOSIDASE; CATIONS; CELL LINE; DNA; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; HUMANS; INJECTIONS; LIPIDS; LUCIFERASES; MICE; MICE, INBRED C57BL; PHOSPHATIDYLETHANOLAMINES; POLYMERS; PULMONARY ALVEOLI; QUATERNARY AMMONIUM COMPOUNDS;

ANIMALIA; ESCHERICHIA COLI;

EID: 0033394513     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301039     Document Type: Article

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