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Volumn 25, Issue 22, 2004, Pages 5293-5301

The effect of the degree of chitosan deacetylation on the efficiency of gene transfection

Author keywords

Chitosan; DNA; Gene expression; Nanoparticles

Indexed keywords

ACETYLATION; DNA; GENES; MOLECULAR WEIGHT; MORPHOLOGY; PROTEINS;

EID: 1942470953     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2003.12.036     Document Type: Article
Times cited : (333)

References (32)
  • 1
    • 0035965501 scopus 로고    scopus 로고
    • Gene delivery with synthetic (non-viral) carriers
    • Brown M.D., Schatzlein A.G., Uchegbu I.F. Gene delivery with synthetic (non-viral) carriers. Int J Pharm. 229(1-2):2001;1-21.
    • (2001) Int J Pharm , vol.229 , Issue.12 , pp. 1-21
    • Brown, M.D.1    Schatzlein, A.G.2    Uchegbu, I.F.3
  • 3
    • 0036535679 scopus 로고    scopus 로고
    • Non-viral gene delivery systems
    • Davis M.E. Non-viral gene delivery systems. Curr Opin Biotechnol. 13(2):2002;128-131.
    • (2002) Curr Opin Biotechnol , vol.13 , Issue.2 , pp. 128-131
    • Davis, M.E.1
  • 4
    • 0032811354 scopus 로고    scopus 로고
    • Poly(ethylenimine) and its role in gene delivery
    • Godbey W.T., Wu K.K., Mikos A.G. Poly(ethylenimine) and its role in gene delivery. J Control Release. 60(2-3):1999;149-160.
    • (1999) J Control Release , vol.60 , Issue.23 , pp. 149-160
    • Godbey, W.T.1    Wu, K.K.2    Mikos, A.G.3
  • 5
    • 0034609633 scopus 로고    scopus 로고
    • Poly(ethylenimine)-mediated transfection: A new paradigm for gene delivery
    • Godbey W.T., Barry M.A., Saggau P., Wu K.K., Mikos A.G. Poly(ethylenimine)-mediated transfection. a new paradigm for gene delivery J Biomed Mater Res. 51(3):2000;321-328.
    • (2000) J Biomed Mater Res , vol.51 , Issue.3 , pp. 321-328
    • Godbey, W.T.1    Barry, M.A.2    Saggau, P.3    Wu, K.K.4    Mikos, A.G.5
  • 6
    • 0033609001 scopus 로고    scopus 로고
    • Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery
    • Godbey W.T., Wu K.K., Mikos A.G. Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery. Proc Natl Acad Sci USA. 96(9):1999;5177-5181.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.9 , pp. 5177-5181
    • Godbey, W.T.1    Wu, K.K.2    Mikos, A.G.3
  • 7
    • 0037072576 scopus 로고    scopus 로고
    • Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
    • Merdan T., Kopecek J., Kissel T. Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv Drug Deliv Rev. 54(5):2002;715-758.
    • (2002) Adv Drug Deliv Rev , vol.54 , Issue.5 , pp. 715-758
    • Merdan, T.1    Kopecek, J.2    Kissel, T.3
  • 8
    • 0031783879 scopus 로고    scopus 로고
    • Chitosan and its use as a pharmaceutical excipient
    • Illum L. Chitosan and its use as a pharmaceutical excipient. Pharm Res. 15(9):1998;1326-1331.
    • (1998) Pharm Res , vol.15 , Issue.9 , pp. 1326-1331
    • Illum, L.1
  • 9
    • 0034658305 scopus 로고    scopus 로고
    • Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microspheres of hyaluronic acid and chitosan
    • Lim S.T., Martin G.P., Berry D.J., Brown M.B. Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microspheres of hyaluronic acid and chitosan. J Control Release. 66(2-3):2000;281-292.
    • (2000) J Control Release , vol.66 , Issue.23 , pp. 281-292
    • Lim, S.T.1    Martin, G.P.2    Berry, D.J.3    Brown, M.B.4
  • 11
    • 0034018067 scopus 로고    scopus 로고
    • Drug release behavior of beads and microgranules of chitosan
    • Gupta K.C., Ravi Kumar M.N. Drug release behavior of beads and microgranules of chitosan. Biomaterials. 21(11):2000;1115-1119.
    • (2000) Biomaterials , vol.21 , Issue.11 , pp. 1115-1119
    • Gupta, K.C.1    Ravi Kumar, M.N.2
  • 13
    • 0035936972 scopus 로고    scopus 로고
    • Chitosan-DNA nanoparticles as gene carriers: Synthesis, characterization and transfection efficiency
    • Mao H.Q., Roy K., Troung-Le V.L., Janes K.A., Lin K.Y., Wang Y.et al. Chitosan-DNA nanoparticles as gene carriers. synthesis, characterization and transfection efficiency J Control Release. 70(3):2001;399-421.
    • (2001) J Control Release , vol.70 , Issue.3 , pp. 399-421
    • Mao, H.Q.1    Roy, K.2    Troung-Le, V.L.3    Janes, K.A.4    Lin, K.Y.5    Wang, Y.6
  • 14
    • 0036382826 scopus 로고    scopus 로고
    • Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection
    • Kumar M., Behera A.K., Lockey R.F., Zhang J., Bhullar G., De La Cruz C.P.et al. Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection. Hum Gene Ther. 13(12):2002;1415-1425.
    • (2002) Hum Gene Ther , vol.13 , Issue.12 , pp. 1415-1425
    • Kumar, M.1    Behera, A.K.2    Lockey, R.F.3    Zhang, J.4    Bhullar, G.5    De La Cruz, C.P.6
  • 15
    • 0032958073 scopus 로고    scopus 로고
    • Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
    • Roy K., Mao H.Q., Huang S.K., Leong K.W. Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat Med. 5(4):1999;387-391.
    • (1999) Nat Med , vol.5 , Issue.4 , pp. 387-391
    • Roy, K.1    Mao, H.Q.2    Huang, S.K.3    Leong, K.W.4
  • 16
    • 0037130565 scopus 로고    scopus 로고
    • Chitosan and its derivatives - A promising non-viral vector for gene transfection
    • Guang Liu W., De Yao K. Chitosan and its derivatives - a promising non-viral vector for gene transfection. J Control Release. 83(1):2002;1-11.
    • (2002) J Control Release , vol.83 , Issue.1 , pp. 1-11
    • Guang Liu, W.1    De Yao, K.2
  • 17
    • 0031722107 scopus 로고    scopus 로고
    • Chitosan-based vector/DNA complexes for gene delivery: Biophysical characteristics and transfection ability
    • Erbacher P., Zou S., Bettinger T., Steffan A.M., Remy J.S. Chitosan-based vector/DNA complexes for gene delivery. biophysical characteristics and transfection ability Pharm Res. 15(9):1998;1332-1339.
    • (1998) Pharm Res , vol.15 , Issue.9 , pp. 1332-1339
    • Erbacher, P.1    Zou, S.2    Bettinger, T.3    Steffan, A.M.4    Remy, J.S.5
  • 18
    • 0029147628 scopus 로고
    • Nonviral gene therapy: The promise of genes as pharmaceutical products
    • Ledley F.D. Nonviral gene therapy. the promise of genes as pharmaceutical products Hum Gene Ther. 6(9):1995;1129-1144.
    • (1995) Hum Gene Ther , vol.6 , Issue.9 , pp. 1129-1144
    • Ledley, F.D.1
  • 19
    • 0036560326 scopus 로고    scopus 로고
    • Intracellular barriers to non-viral gene transfer
    • Lechardeur D., Lukacs G.L. Intracellular barriers to non-viral gene transfer. Curr Gene Ther. 2(2):2002;183-194.
    • (2002) Curr Gene Ther , vol.2 , Issue.2 , pp. 183-194
    • Lechardeur, D.1    Lukacs, G.L.2
  • 22
    • 0035668731 scopus 로고    scopus 로고
    • Interactions of phospholipid bilayer with chitosan: Effect of molecular weight and pH
    • Fang N., Chan V., Mao H.Q., Leong K.W. Interactions of phospholipid bilayer with chitosan. effect of molecular weight and pH Biomacromolecules. 2(4):2001;1161-1168.
    • (2001) Biomacromolecules , vol.2 , Issue.4 , pp. 1161-1168
    • Fang, N.1    Chan, V.2    Mao, H.Q.3    Leong, K.W.4
  • 23
    • 0035424424 scopus 로고    scopus 로고
    • In vitro gene delivery mediated by chitosan. Effect of pH, serum, and molecular mass of chitosan on the transfection efficiency
    • Sato T., Ishii T., Okahata Y. In vitro gene delivery mediated by chitosan. Effect of pH, serum, and molecular mass of chitosan on the transfection efficiency. Biomaterials. 22(15):2001;2075-2080.
    • (2001) Biomaterials , vol.22 , Issue.15 , pp. 2075-2080
    • Sato, T.1    Ishii, T.2    Okahata, Y.3
  • 24
    • 0024719541 scopus 로고
    • Studies on chitosan: 2. Solution stability and reactivity of partially N-acetylated chitosan derivatives in aqueous media
    • Aiba S. Studies on chitosan. 2. Solution stability and reactivity of partially N-acetylated chitosan derivatives in aqueous media Int J Biol Macromol. 11(4):1989;249-252.
    • (1989) Int J Biol Macromol , vol.11 , Issue.4 , pp. 249-252
    • Aiba, S.1
  • 25
    • 0026013604 scopus 로고
    • Studies on chitosan: 3. Evidence for the presence of random and block copolymer structures in partially N-acetylated chitosans
    • Aiba S. Studies on chitosan. 3. Evidence for the presence of random and block copolymer structures in partially N-acetylated chitosans Int J Biol Macromol. 13(1):1991;40-44.
    • (1991) Int J Biol Macromol , vol.13 , Issue.1 , pp. 40-44
    • Aiba, S.1
  • 26
    • 0026749078 scopus 로고
    • Studies on chitosan: 4. Lysozymic hydrolysis of partially N-acetylated chitosans
    • Aiba S. Studies on chitosan. 4. lysozymic hydrolysis of partially N-acetylated chitosans Int J Biol Macromol. 14(4):1992;225-228.
    • (1992) Int J Biol Macromol , vol.14 , Issue.4 , pp. 225-228
    • Aiba, S.1
  • 27
    • 0032916739 scopus 로고    scopus 로고
    • Biodegradation and distribution of water-soluble chitosan in mice
    • Onishi H., Machida Y. Biodegradation and distribution of water-soluble chitosan in mice. Biomaterials. 20(2):1999;175-182.
    • (1999) Biomaterials , vol.20 , Issue.2 , pp. 175-182
    • Onishi, H.1    MacHida, Y.2
  • 28
    • 0031127883 scopus 로고    scopus 로고
    • In vitro and in vivo degradation of films of chitin and its deacetylated derivatives
    • Tomihata K., Ikada Y. In vitro and in vivo degradation of films of chitin and its deacetylated derivatives. Biomaterials. 18(7):1997;567-575.
    • (1997) Biomaterials , vol.18 , Issue.7 , pp. 567-575
    • Tomihata, K.1    Ikada, Y.2
  • 29
    • 0034786764 scopus 로고    scopus 로고
    • Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo
    • Koping-Hoggard M., Tubulekas I., Guan H., Edwards K., Nilsson M., Varum K.M.et al. Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo. Gene Ther. 8(14):2001;1108-1121.
    • (2001) Gene Ther , vol.8 , Issue.14 , pp. 1108-1121
    • Koping-Hoggard, M.1    Tubulekas, I.2    Guan, H.3    Edwards, K.4    Nilsson, M.5    Varum, K.M.6
  • 30
    • 0032990267 scopus 로고    scopus 로고
    • Potential of low molecular mass chitosan as a DNA delivery system: Biocompatibility, body distribution and ability to complex and protect DNA
    • Richardson S.C., Kolbe H.V., Duncan R. Potential of low molecular mass chitosan as a DNA delivery system. biocompatibility, body distribution and ability to complex and protect DNA Int J Pharm. 178(2):1999;231-243.
    • (1999) Int J Pharm , vol.178 , Issue.2 , pp. 231-243
    • Richardson, S.C.1    Kolbe, H.V.2    Duncan, R.3
  • 31
    • 0028648428 scopus 로고
    • Preparation of N-acetylchitooligosaccharides by hydrolysis of chitosan with chitinase followed by N-acetylation
    • Aiba S. Preparation of N-acetylchitooligosaccharides by hydrolysis of chitosan with chitinase followed by N-acetylation. Carbohydr Res. 265(2):1994;323-328.
    • (1994) Carbohydr Res , vol.265 , Issue.2 , pp. 323-328
    • Aiba, S.1
  • 32
    • 46549101029 scopus 로고
    • Determination of the degree of acetylation of chitosans by first derivative ultraviolet spectrophotometry
    • Muzzarelli R.A.A., Rocchetti R. Determination of the degree of acetylation of chitosans by first derivative ultraviolet spectrophotometry. Carbohydrate Polym. 5:1985;461-472.
    • (1985) Carbohydrate Polym , vol.5 , pp. 461-472
    • Muzzarelli, R.A.A.1    Rocchetti, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.