Gene silencing activity of siRNA polyplexes based on biodegradable polymers

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 77, Issue 3, 2011, Pages 450-457

  Varkouhi, Amir K ^a   Lammers, Twan ^a,b   Schiffelers, Raymond M ^a   Van Steenbergen, Mies J ^a   Hennink, Wim E ^a   Storm, Gert ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Cytotoxicity; Fusogenic peptides; Gene silencing; Photochemical internalization; Polymeric vectors; siRNA

Indexed keywords

[POLY((2 HYDROXYPROPYL) METHACRYLAMIDE 1 METHYL 2 PIPERIDINE METHANOL)]; [POLY(2 DIMETHYLAMINO)ETHYL METHACRYLATE]; CATION; CHITOSAN DERIVATIVE; FIREFLY LUCIFERASE; LIPOFECTAMINE; POLYETHYLENEIMINE; POLYMER; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADABILITY; CARCINOMA CELL; CYTOTOXICITY; ENDOSOME; GENE SILENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG CANCER; NONHUMAN; PHOTOCHEMICAL INTERNALIZATION; PHYSICAL CHEMISTRY; SERUM;

ACRYLIC RESINS; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; CELL SURVIVAL; CHITOSAN; DRUG CARRIERS; ELECTROPHORESIS, AGAR GEL; GENE SILENCING; HUMANS; MICROSCOPY, CONFOCAL; MOLECULAR STRUCTURE; RNA, SMALL INTERFERING; SURFACE PROPERTIES; TRANSFECTION;

EID: 79952313198     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.11.016     Document Type: Article

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