메뉴 건너뛰기




Volumn 287, Issue 7, 2012, Pages 4609-4627

Nrf2b, novel zebrafish paralog of oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT DEFENSE; ANTIOXIDANT RESPONSE ELEMENTS; CONSERVED SYNTENY; DANIO RERIO; DEVELOPMENTAL MODELS; DIFFERENT MECHANISMS; EMBRYONIC DEVELOPMENT; GENE EXPRESSION PROFILING; HEME OXYGENASE-1; HOX GENE; NEGATIVE REGULATORS; OXIDATIVE DAMAGE; PARALOGS; PROTEIN SEQUENCES; SIGNALING PATHWAYS; SUBFUNCTIONS; TERT-BUTYLHYDROPEROXIDE; TRANSACTIVATION DOMAIN; ZEBRAFISH;

EID: 84856914437     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.260125     Document Type: Article
Times cited : (90)

References (89)
  • 1
    • 67649402187 scopus 로고    scopus 로고
    • The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress
    • Nguyen, T., Nioi, P., and Pickett, C. B. (2009) The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J. Biol. Chem. 284, 13291-13295
    • (2009) J. Biol. Chem. , vol.284 , pp. 13291-13295
    • Nguyen, T.1    Nioi, P.2    Pickett, C.B.3
  • 2
    • 33847050801 scopus 로고    scopus 로고
    • Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
    • Kensler, T. W., Wakabayashi, N., and Biswal, S. (2007) Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 47, 89-116
    • (2007) Annu. Rev. Pharmacol. Toxicol. , vol.47 , pp. 89-116
    • Kensler, T.W.1    Wakabayashi, N.2    Biswal, S.3
  • 3
    • 0242580049 scopus 로고    scopus 로고
    • Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress
    • DOI 10.1128/MCB.23.22.8137-8151.2003
    • Zhang, D. D., and Hannink, M. (2003) Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol. Cell. Biol. 23, 8137-8151 (Pubitemid 37377505)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.22 , pp. 8137-8151
    • Zhang, D.D.1    Hannink, M.2
  • 4
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., Igarashi, K., Engel, J. D., and Yamamoto, M. (1999) Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 13, 76-86 (Pubitemid 29045117)
    • (1999) Genes and Development , vol.13 , Issue.1 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6    Yamamoto, M.7
  • 5
    • 20144385916 scopus 로고    scopus 로고
    • Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: Direct cross-talk between phase I and II drug-metabolizing enzymes
    • DOI 10.1074/jbc.M412081200
    • Miao, W., Hu, L., Scrivens, P. J., and Batist, G. (2005) Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway. Direct cross-talk between phase I and II drug-metabolizing enzymes. J. Biol. Chem. 280, 20340-20348 (Pubitemid 40776732)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.21 , pp. 20340-20348
    • Miao, W.1    Hu, L.2    Scrivens, P.J.3    Batist, G.4
  • 7
    • 79955466298 scopus 로고    scopus 로고
    • The effect of Nrf2 knockout on the constitutive expression of drug metabolizing enzymes and transporters in C57Bl/6 mice livers
    • Anwar-Mohamed, A., Degenhardt, O. S., El Gendy, M. A., Seubert, J. M., Kleeberger, S. R., and El-Kadi, A. O. (2011) The effect of Nrf2 knockout on the constitutive expression of drug metabolizing enzymes and transporters in C57Bl/6 mice livers. Toxicol. in Vitro 25, 785-795
    • (2011) Toxicol. in Vitro , vol.25 , pp. 785-795
    • Anwar-Mohamed, A.1    Degenhardt, O.S.2    El Gendy, M.A.3    Seubert, J.M.4    Kleeberger, S.R.5    El-Kadi, A.O.6
  • 8
    • 84901421880 scopus 로고    scopus 로고
    • Perspectives on zebrafish as a model in environmental toxicology
    • (Perry, S. F., Ekker, M., Farrell, A. P., and Brauner, C. J., eds) Academic Press, Inc., New York
    • Stegeman, J. J., Goldstone, J. V., and Hahn, M. E. (2010) Perspectives on zebrafish as a model in environmental toxicology. in Zebrafish (Fish Physiology) (Perry, S. F., Ekker, M., Farrell, A. P., and Brauner, C. J., eds) pp. 367-439, Academic Press, Inc., New York
    • (2010) Zebrafish (Fish Physiology) , pp. 367-439
    • Stegeman, J.J.1    Goldstone, J.V.2    Hahn, M.E.3
  • 9
    • 4444340536 scopus 로고    scopus 로고
    • Subfunction partitioning, the teleost radiation and the annotation of the human genome
    • DOI 10.1016/j.tig.2004.08.001, PII S0168952504002136
    • Postlethwait, J., Amores, A., Cresko, W., Singer, A., and Yan, Y. L. (2004) Subfunction partitioning, the teleost radiation and the annotation of the human genome. Trends Genet. 20, 481-490 (Pubitemid 39201068)
    • (2004) Trends in Genetics , vol.20 , Issue.10 , pp. 481-490
    • Postlethwait, J.1    Amores, A.2    Cresko, W.3    Singer, A.4    Yan, Y.-L.5
  • 10
    • 0036668466 scopus 로고    scopus 로고
    • Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system
    • DOI 10.1046/j.1365-2443.2002.00561.x
    • Kobayashi, M., Itoh, K., Suzuki, T., Osanai, H., Nishikawa, K., Katoh, Y., Takagi, Y., and Yamamoto, M. (2002) Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system. Genes Cells 7, 807-820 (Pubitemid 34947084)
    • (2002) Genes to Cells , vol.7 , Issue.8 , pp. 807-820
    • Kobayashi, M.1    Itoh, K.2    Suzuki, T.3    Osanai, H.4    Nishikawa, K.5    Katoh, Y.6    Takagi, Y.7    Yamamoto, M.8
  • 12
    • 66149090319 scopus 로고    scopus 로고
    • Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish
    • Timme-Laragy, A. R., Van Tiem, L. A., Linney, E. A., and Di Giulio, R. T. (2009) Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish. Toxicol. Sci. 109, 217-227
    • (2009) Toxicol. Sci. , vol.109 , pp. 217-227
    • Timme-Laragy, A.R.1    Van Tiem, L.A.2    Linney, E.A.3    Di Giulio, R.T.4
  • 13
    • 41249083049 scopus 로고    scopus 로고
    • Molecular evolution of Keap1. Two Keap1 molecules with distinctive intervening region structures are conserved among fish
    • Li, L., Kobayashi, M., Kaneko, H., Nakajima-Takagi, Y., Nakayama, Y., and Yamamoto, M. (2008) Molecular evolution of Keap1. Two Keap1 molecules with distinctive intervening region structures are conserved among fish. J. Biol. Chem. 283, 3248-3255
    • (2008) J. Biol. Chem. , vol.283 , pp. 3248-3255
    • Li, L.1    Kobayashi, M.2    Kaneko, H.3    Nakajima-Takagi, Y.4    Nakayama, Y.5    Yamamoto, M.6
  • 14
    • 0034656017 scopus 로고    scopus 로고
    • Activation of transcription factors in zebrafish cell cultures by environmental pollutants
    • DOI 10.1006/abbi.2000.1727
    • Carvan, M. J., 3rd, Solis, W. A., Gedamu, L., and Nebert, D. W. (2000) Activation of transcription factors in zebrafish cell cultures by environmental pollutants. Arch. Biochem. Biophys. 376, 320-327 (Pubitemid 30210879)
    • (2000) Archives of Biochemistry and Biophysics , vol.376 , Issue.2 , pp. 320-327
    • Carvan III, M.J.1    Solis, W.A.2    Gedamu, L.3    Nebert, D.W.4
  • 15
    • 0035796811 scopus 로고    scopus 로고
    • Oxidative stress in zebrafish cells: Potential utility of transgenic zebrafish as a deployable sentinel for site hazard ranking
    • DOI 10.1016/S0048-9697(01)00742-2, PII S0048969701007422
    • Carvan, M. J., 3rd, Sonntag, D. M., Cmar, C. B., Cook, R. S., Curran, M. A., and Miller, G. L. (2001) Oxidative stress in zebrafish cells. Potential utility of transgenic zebrafish as a deployable sentinel for site hazard ranking. Sci. Total Environ. 274, 183-196 (Pubitemid 32591392)
    • (2001) Science of the Total Environment , vol.274 , Issue.1-3 , pp. 183-196
    • Carvan III, M.J.1    Sonntag, D.M.2    Cmar, C.B.3    Cook, R.S.4    Curran, M.A.5    Miller, G.L.6
  • 16
    • 19544372581 scopus 로고    scopus 로고
    • Pi class glutathione S-transferase genes are regulated by Nrf2 through an evolutionarily conserved regulatory element in zebrafish
    • DOI 10.1042/BJ20041860
    • Suzuki, T., Takagi, Y., Osanai, H., Li, L., Takeuchi, M., Katoh, Y., Kobayashi, M., and Yamamoto, M. (2005) Pi class glutathione S-transferase genes are regulated by Nrf 2 through an evolutionarily conserved regulatory element in zebrafish. Biochem. J. 388, 65-73 (Pubitemid 40732933)
    • (2005) Biochemical Journal , vol.388 , Issue.1 , pp. 65-73
    • Suzuki, T.1    Takagi, Y.2    Osanai, H.3    Li, L.I.4    Takeuchi, M.5    Katoh, Y.6    Kobayashi, M.7    Yamamoto, M.8
  • 17
    • 55949099524 scopus 로고    scopus 로고
    • Detection of mercury in aquatic environments using EPRE reporter zebrafish
    • Kusik, B. W., Carvan, M. J., 3rd, and Udvadia, A. J. (2008) Detection of mercury in aquatic environments using EPRE reporter zebrafish. Marine Biotechnol. 10, 750-757
    • (2008) Marine Biotechnol. , vol.10 , pp. 750-757
    • Kusik, B.W.1    Carvan III, M.J.2    Udvadia, A.J.3
  • 18
    • 26244444380 scopus 로고    scopus 로고
    • From 2R to 3R: Evidence for a fish-specific genome duplication (FSGD)
    • DOI 10.1002/bies.20293
    • Meyer, A., and Van de Peer, Y. (2005) From 2R to 3R. Evidence for a fish-specific genome duplication (FSGD). BioEssays 27, 937-945 (Pubitemid 41415948)
    • (2005) BioEssays , vol.27 , Issue.9 , pp. 937-945
    • Meyer, A.1    Van De, P.Y.2
  • 19
    • 34247858961 scopus 로고    scopus 로고
    • Basal and 3,3′,4,4′,5-pentachlorobiphenyl-induced expression of cytochrome P450 1A, 1B and 1C genes in zebrafish
    • DOI 10.1016/j.taap.2007.02.017, PII S0041008X07000877
    • Jönsson, M. E., Orrego, R., Woodin, B. R., Goldstone, J. V., and Stegeman, J. J. (2007) Basal and 3,3′,4,4′,5-pentachlorobiphenyl- induced expression of cytochrome P450 1A, 1B, and 1C genes in zebrafish. Toxicol. Appl. Pharmacol. 221, 29-41 (Pubitemid 46702278)
    • (2007) Toxicology and Applied Pharmacology , vol.221 , Issue.1 , pp. 29-41
    • Jonsson, M.E.1    Orrego, R.2    Woodin, B.R.3    Goldstone, J.V.4    Stegeman, J.J.5
  • 20
    • 0031574072 scopus 로고    scopus 로고
    • The CLUSTAL X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
    • DOI 10.1093/nar/25.24.4876
    • Thompson, J. D., Gibson, T. J., Plewniak, F., Jeanmougin, F., and Higgins, D. G. (1997) The CLUSTAL-X Windows interface. Flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25, 4876-4882 (Pubitemid 28022245)
    • (1997) Nucleic Acids Research , vol.25 , Issue.24 , pp. 4876-4882
    • Thompson, J.D.1    Gibson, T.J.2    Plewniak, F.3    Jeanmougin, F.4    Higgins, D.G.5
  • 21
    • 3042666256 scopus 로고    scopus 로고
    • MUSCLE. Multiple sequence alignment with high accuracy and high throughput
    • Edgar, R. C. (2004) MUSCLE. Multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res. 32, 1792-1797
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1792-1797
    • Edgar, R.C.1
  • 23
    • 33750403801 scopus 로고    scopus 로고
    • RAxML-VI-HPC. Maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models
    • Stamatakis, A. (2006) RAxML-VI-HPC. Maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics 22, 2688-2690
    • (2006) Bioinformatics , vol.22 , pp. 2688-2690
    • Stamatakis, A.1
  • 27
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson, J. D., Higgins, D. G., and Gibson, T. J. (1994) CLUSTAL W. Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties, and weight matrix choice. Nucleic Acids Res. 22, 4673-4680 (Pubitemid 24354800)
    • (1994) Nucleic Acids Research , vol.22 , Issue.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 28
    • 38549153970 scopus 로고    scopus 로고
    • Repression of Aryl Hydrocarbon Receptor (AHR) signaling by AHR repressor: Role of DNA binding and competition for AHR nuclear translocator
    • DOI 10.1124/mol.107.040204
    • Evans, B. R., Karchner, S. I., Allan, L. L., Pollenz, R. S., Tanguay, R. L., Jenny, M. J., Sherr, D. H., and Hahn, M. E. (2008) Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor. Role of DNA binding and competition for AHR nuclear translocator. Mol. Pharmacol. 73, 387-398 (Pubitemid 351159209)
    • (2008) Molecular Pharmacology , vol.73 , Issue.2 , pp. 387-398
    • Evans, B.R.1    Karchner, S.I.2    Allan, L.L.3    Pollenz, R.S.4    Tanguay, R.L.5    Jenny, M.J.6    Sherr, D.H.7    Hahn, M.E.8
  • 29
    • 0242268495 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor 2 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafish
    • DOI 10.1093/toxsci/kfg202
    • Prasch, A. L., Teraoka, H., Carney, S. A., Dong, W., Hiraga, T., Stegeman, J. J., Heideman, W., and Peterson, R. E. (2003) Aryl hydrocarbon receptor 2 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafish. Toxicol. Sci. 76, 138-150 (Pubitemid 37361893)
    • (2003) Toxicological Sciences , vol.76 , Issue.1 , pp. 138-150
    • Prasch, A.L.1    Teraoka, H.2    Carney, S.A.3    Dong, W.4    Hiraga, T.5    Stegeman, J.J.6    Heideman, W.7    Peterson, R.E.8
  • 30
    • 67650711644 scopus 로고    scopus 로고
    • Distinct roles of two zebrafish AHR repressors (AHRRa and AHRRb) in embryonic development and regulating the response to 2,3,7,8-tetrachlorodibenzo- p-dioxin
    • Jenny, M. J., Karchner, S. I., Franks, D. G., Woodin, B. R., Stegeman, J. J., and Hahn, M. E. (2009) Distinct roles of two zebrafish AHR repressors (AHRRa and AHRRb) in embryonic development and regulating the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 110, 426-441
    • (2009) Toxicol. Sci. , vol.110 , pp. 426-441
    • Jenny, M.J.1    Karchner, S.I.2    Franks, D.G.3    Woodin, B.R.4    Stegeman, J.J.5    Hahn, M.E.6
  • 32
    • 57049147881 scopus 로고    scopus 로고
    • Characterization of housekeeping genes in zebrafish. Male-female differences and effects of tissue type, developmental stage, and chemical treatment
    • McCurley, A. T., and Callard, G. V. (2008) Characterization of housekeeping genes in zebrafish. Male-female differences and effects of tissue type, developmental stage, and chemical treatment. BMC Mol. Biol. 9, 102
    • (2008) BMC Mol. Biol. , vol.9 , pp. 102
    • McCurley, A.T.1    Callard, G.V.2
  • 33
    • 0035710746 scopus 로고    scopus 로고
    • -deltadeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak, K. J., and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 25, 402-408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 36
    • 2942549112 scopus 로고    scopus 로고
    • A simple tool to enhance sensitivity and facilitate interpretation of microarray experiments
    • Iterative Group Analysis (iGA)
    • Breitling, R., Amtmann, A., and Herzyk, P. (2004) Iterative Group Analysis (iGA). A simple tool to enhance sensitivity and facilitate interpretation of microarray experiments. BMC Bioinformatics 5, 34
    • (2004) BMC Bioinformatics , vol.5 , pp. 34
    • Breitling, R.1    Amtmann, A.2    Herzyk, P.3
  • 37
  • 41
    • 34250213457 scopus 로고    scopus 로고
    • The zebrafish genome. A review and msx gene case study
    • Postlethwait, J. H. (2006) The zebrafish genome. A review and msx gene case study. Genome Dynamics 2, 183-197
    • (2006) Genome Dynamics , vol.2 , pp. 183-197
    • Postlethwait, J.H.1
  • 42
    • 34948908604 scopus 로고    scopus 로고
    • The zebrafish genome in context. Ohnologs gone missing
    • Postlethwait, J. H. (2007) The zebrafish genome in context. Ohnologs gone missing. J. Exp. Zool. B Mol. Dev. Evol. 308, 563-577
    • (2007) J. Exp. Zool. B Mol. Dev. Evol. , vol.308 , pp. 563-577
    • Postlethwait, J.H.1
  • 43
    • 53749095111 scopus 로고    scopus 로고
    • Phylogenetic and chromosomal analyses of multiple gene families syntenic with vertebrate Hox clusters
    • Sundström, G., Larsson, T. A., and Larhammar, D. (2008) Phylogenetic and chromosomal analyses of multiple gene families syntenic with vertebrate Hox clusters. BMC Evol. Biol. 8, 254
    • (2008) BMC Evol. Biol. , vol.8 , pp. 254
    • Sundström, G.1    Larsson, T.A.2    Larhammar, D.3
  • 45
    • 33745294114 scopus 로고    scopus 로고
    • The zebrafish hoxDb cluster has been reduced to a single microRNA
    • DOI 10.1038/ng0606-601, PII N0606601
    • Woltering, J. M., and Durston, A. J. (2006) The zebrafish hoxDb cluster has been reduced to a single microRNA. Nature genetics 38, 601-602 (Pubitemid 43932891)
    • (2006) Nature Genetics , vol.38 , Issue.6 , pp. 601-602
    • Woltering, J.M.1    Durston, A.J.2
  • 46
    • 78751703950 scopus 로고    scopus 로고
    • Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
    • Taguchi, K., Motohashi, H., and Yamamoto, M. (2011) Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution. Genes Cells 16, 123-140
    • (2011) Genes Cells , vol.16 , pp. 123-140
    • Taguchi, K.1    Motohashi, H.2    Yamamoto, M.3
  • 47
    • 77958126450 scopus 로고    scopus 로고
    • Cellular stress responses, the hormesis paradigm, and vitagenes. Novel targets for therapeutic intervention in neurodegenerative disorders
    • Calabrese, V., Cornelius, C., Dinkova-Kostova, A. T., Calabrese, E. J., and Mattson, M. P. (2010) Cellular stress responses, the hormesis paradigm, and vitagenes. Novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid. Redox Signal. 13, 1763-1811
    • (2010) Antioxid. Redox Signal. , vol.13 , pp. 1763-1811
    • Calabrese, V.1    Cornelius, C.2    Dinkova-Kostova, A.T.3    Calabrese, E.J.4    Mattson, M.P.5
  • 48
    • 77149175946 scopus 로고    scopus 로고
    • Oxidative stress targets in pulmonary emphysema. Focus on the Nrf2 pathway
    • Boutten, A., Goven, D., Boczkowski, J., and Bonay, M. (2010) Oxidative stress targets in pulmonary emphysema. Focus on the Nrf2 pathway. Expert Opin. Ther. Targets 14, 329-346
    • (2010) Expert Opin. Ther. Targets , vol.14 , pp. 329-346
    • Boutten, A.1    Goven, D.2    Boczkowski, J.3    Bonay, M.4
  • 49
    • 67650453921 scopus 로고    scopus 로고
    • Targeting the Nrf2 pathway against cardiovascular disease
    • Li, J., Ichikawa, T., Janicki, J. S., and Cui, T. (2009) Targeting the Nrf2 pathway against cardiovascular disease. Expert Opin. Ther. Targets 13, 785-794
    • (2009) Expert Opin. Ther. Targets , vol.13 , pp. 785-794
    • Li, J.1    Ichikawa, T.2    Janicki, J.S.3    Cui, T.4
  • 50
    • 0036240610 scopus 로고    scopus 로고
    • Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: Role of antioxidant response element-like sequences in the nrf2 promoter
    • DOI 10.1128/MCB.22.9.2883-2892.2002
    • Kwak, M. K., Itoh, K., Yamamoto, M., and Kensler, T. W. (2002) Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents. Role of antioxidant response element-like sequences in the nrf2 promoter. Mol. Cell. Biol. 22, 2883-2892 (Pubitemid 34437448)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.9 , pp. 2883-2892
    • Kwak, M.-K.1    Itoh, K.2    Yamamoto, M.3    Kensler, T.W.4
  • 51
    • 79951956638 scopus 로고    scopus 로고
    • Transcription factor Nrf2 maintains the basal expression of Mdm2. An implication of the regulation of p53 signaling by Nrf2
    • You, A., Nam, C. W., Wakabayashi, N., Yamamoto, M., Kensler, T. W., and Kwak, M. K. (2011) Transcription factor Nrf2 maintains the basal expression of Mdm2. An implication of the regulation of p53 signaling by Nrf2. Arch. Biochem. Biophys. 507, 356-364
    • (2011) Arch. Biochem. Biophys. , vol.507 , pp. 356-364
    • You, A.1    Nam, C.W.2    Wakabayashi, N.3    Yamamoto, M.4    Kensler, T.W.5    Kwak, M.K.6
  • 52
    • 1842584947 scopus 로고    scopus 로고
    • Applied bioinformatics for the identification of regulatory elements
    • DOI 10.1038/nrg1315
    • Wasserman, W. W., and Sandelin, A. (2004) Applied bioinformatics for the identification of regulatory elements. Nat. Rev. Genet. 5, 276-287 (Pubitemid 38435623)
    • (2004) Nature Reviews Genetics , vol.5 , Issue.4 , pp. 276-287
    • Wasserman, W.W.1    Sandelin, A.2
  • 53
    • 0037192626 scopus 로고    scopus 로고
    • Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene
    • DOI 10.1038/sj.onc.1205288
    • Bloom, D., Dhakshinamoorthy, S., and Jaiswal, A. K. (2002) Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to up-regulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase 1 gene. Oncogene 21, 2191-2200 (Pubitemid 34311373)
    • (2002) Oncogene , vol.21 , Issue.14 , pp. 2191-2200
    • Bloom, D.1    Dhakshinamoorthy, S.2    Jaiswal, A.K.3
  • 54
    • 66349129338 scopus 로고    scopus 로고
    • Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response
    • Sun, Z., Chin, Y. E., and Zhang, D. D. (2009) Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response. Mol. Cell. Biol. 29, 2658-2672
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 2658-2672
    • Sun, Z.1    Chin, Y.E.2    Zhang, D.D.3
  • 55
    • 33344463325 scopus 로고    scopus 로고
    • Keap1 recruits Neh2 through binding to ETGE and DLG motifs. Characterization of the two-site molecular recognition model
    • Tong, K. I., Katoh, Y., Kusunoki, H., Itoh, K., Tanaka, T., and Yamamoto, M. (2006) Keap1 recruits Neh2 through binding to ETGE and DLG motifs. Characterization of the two-site molecular recognition model. Mol. Cell. Biol. 26, 2887-2900
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2887-2900
    • Tong, K.I.1    Katoh, Y.2    Kusunoki, H.3    Itoh, K.4    Tanaka, T.5    Yamamoto, M.6
  • 56
    • 33750613056 scopus 로고    scopus 로고
    • Two-site substrate recognition model for the Keap1-Nrf2 system: A hinge and latch mechanism
    • DOI 10.1515/BC.2006.164, PII BCHM38710111311
    • Tong, K. I., Kobayashi, A., Katsuoka, F., and Yamamoto, M. (2006) Twosite substrate recognition model for the Keap1-Nrf2 system. A hinge and latch mechanism. Biol. Chem. 387, 1311-1320 (Pubitemid 44691409)
    • (2006) Biological Chemistry , vol.387 , Issue.10-11 , pp. 1311-1320
    • Tong, K.I.1    Kobayashi, A.2    Katsuoka, F.3    Yamamoto, M.4
  • 57
    • 33747728194 scopus 로고    scopus 로고
    • Dimerization of substrate adaptors can facilitate Cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: A two-site interaction model for the Nrf2-Keap1 complex
    • DOI 10.1074/jbc.M601119200
    • McMahon, M., Thomas, N., Itoh, K., Yamamoto, M., and Hayes, J. D. (2006) Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism. A two-site interaction model for the Nrf2-Keap1 complex. J. Biol. Chem. 281, 24756-24768 (Pubitemid 44274250)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.34 , pp. 24756-24768
    • McMahon, M.1    Thomas, N.2    Itoh, K.3    Yamamoto, M.4    Hayes, J.D.5
  • 58
    • 3843104763 scopus 로고    scopus 로고
    • Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron
    • DOI 10.1074/jbc.M403061200
    • McMahon, M., Thomas, N., Itoh, K., Yamamoto, M., and Hayes, J. D. (2004) Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox- insensitive Neh6 degron. J. Biol. Chem. 279, 31556-31567 (Pubitemid 39037824)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.30 , pp. 31556-31567
    • McMahon, M.1    Thomas, N.2    Itoh, K.3    Yamamoto, M.4    Hayes, J.D.5
  • 60
    • 10044228504 scopus 로고    scopus 로고
    • Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
    • DOI 10.1128/MCB.24.24.10941-10953.2004
    • Zhang, D. D., Lo, S. C., Cross, J. V., Templeton, D. J., and Hannink, M. (2004) Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol. Cell. Biol. 24, 10941-10953 (Pubitemid 39603148)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.24 , pp. 10941-10953
    • Zhang, D.D.1    Lo, S.-C.2    Cross, J.V.3    Templeton, D.J.4    Hannink, M.5
  • 61
    • 28544450507 scopus 로고    scopus 로고
    • The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation
    • DOI 10.1128/MCB.25.24.10895-10906.2005
    • Nioi, P., Nguyen, T., Sherratt, P. J., and Pickett, C. B. (2005) The carboxyl-terminal Neh3 domain of Nrf2 is required for transcriptional activation. Mol. Cell. Biol. 25, 10895-10906 (Pubitemid 41747133)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.24 , pp. 10895-10906
    • Nioi, P.1    Nguyen, T.2    Sherratt, P.J.3    Pickett, C.B.4
  • 62
    • 34447526197 scopus 로고    scopus 로고
    • GSK-3β acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2
    • DOI 10.1074/jbc.M611336200
    • Jain, A. K., and Jaiswal, A. K. (2007) GSK-3β acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2-related factor 2. J. Biol. Chem. 282, 16502-16510 (Pubitemid 47100395)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.22 , pp. 16502-16510
    • Jain, A.K.1    Jaiswal, A.K.2
  • 63
    • 33846971625 scopus 로고    scopus 로고
    • Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function
    • Li, Z., Dong, T., Pröschel, C., and Noble, M. (2007) Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function. PLoS Biol. 5, e35
    • (2007) PLoS Biol. , vol.5
    • Li, Z.1    Dong, T.2    Pröschel, C.3    Noble, M.4
  • 66
    • 23844475091 scopus 로고    scopus 로고
    • Nuclear import and export signals in control of Nrf2
    • DOI 10.1074/jbc.M502083200
    • Jain, A. K., Bloom, D. A., and Jaiswal, A. K. (2005) Nuclear import and export signals in control of Nrf2. J. Biol. Chem. 280, 29158-29168 (Pubitemid 41161367)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.32 , pp. 29158-29168
    • Jain, A.K.1    Bloom, D.A.2    Jaiswal, A.K.3
  • 67
    • 79953225194 scopus 로고    scopus 로고
    • Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localization
    • Kawai, Y., Garduño, L., Theodore, M., Yang, J., and Arinze, I. J. (2011) Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localization. J. Biol. Chem. 286, 7629-7640
    • (2011) J. Biol. Chem. , vol.286 , pp. 7629-7640
    • Kawai, Y.1    Garduño, L.2    Theodore, M.3    Yang, J.4    Arinze, I.J.5
  • 70
    • 11444261268 scopus 로고    scopus 로고
    • Gene expression profiling of NRF2-mediated protection against oxidative injury
    • DOI 10.1016/j.freeradbiomed.2004.10.013, PII S0891584904008354
    • Cho, H. Y., Reddy, S. P., Debiase, A., Yamamoto, M., and Kleeberger, S. R. (2005) Gene expression profiling of NRF2-mediated protection against oxidative injury. Free Radic. Biol. Med. 38, 325-343 (Pubitemid 40081112)
    • (2005) Free Radical Biology and Medicine , vol.38 , Issue.3 , pp. 325-343
    • Cho, H.-Y.1    Reddy, S.P.2    DeBiase, A.3    Yamamoto, M.4    Kleeberger, S.R.5
  • 71
    • 0038146898 scopus 로고    scopus 로고
    • Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
    • DOI 10.1074/jbc.M211558200
    • Lee, J. M., Calkins, M. J., Chan, K., Kan, Y. W., and Johnson, J. A. (2003) Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. J. Biol. Chem. 278, 12029-12038 (Pubitemid 36800179)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.14 , pp. 12029-12038
    • Lee, J.-M.1    Calkins, M.J.2    Chan, K.3    Kan, Y.W.4    Johnson, J.A.5
  • 72
    • 69249230784 scopus 로고    scopus 로고
    • Transcriptional regulation of rat γ-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element
    • Shenvi, S. V., Smith, E. J., and Hagen, T. M. (2009) Transcriptional regulation of rat γ-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element. Pharmacol. Res. 60, 229-236
    • (2009) Pharmacol. Res. , vol.60 , pp. 229-236
    • Shenvi, S.V.1    Smith, E.J.2    Hagen, T.M.3
  • 74
    • 78649635403 scopus 로고    scopus 로고
    • Nrf2, a guardian of healthspan and gatekeeper of species longevity
    • Lewis, K. N., Mele, J., Hayes, J. D., and Buffenstein, R. (2010) Nrf2, a guardian of healthspan and gatekeeper of species longevity. Integr. Comp.Biol. 50, 829-843
    • (2010) Integr. Comp.Biol. , vol.50 , pp. 829-843
    • Lewis, K.N.1    Mele, J.2    Hayes, J.D.3    Buffenstein, R.4
  • 75
    • 0030451213 scopus 로고    scopus 로고
    • NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development
    • DOI 10.1073/pnas.93.24.13943
    • Chan, K., Lu, R., Chang, J. C., and Kan, Y. W. (1996) NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. Proc. Natl. Acad. Sci. U.S.A. 93,13943-13948 (Pubitemid 26424225)
    • (1996) Proceedings of the National Academy of Sciences of the United States of America , vol.93 , Issue.24 , pp. 13943-13948
    • Chan, K.1    Lu, R.2    Chang, J.C.3    Kan, Y.W.4
  • 77
  • 79
    • 33748893228 scopus 로고    scopus 로고
    • Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion
    • DOI 10.1016/j.abb.2006.08.005, PII S0003986106002876
    • Osburn, W. O., Wakabayashi, N., Misra, V., Nilles, T., Biswal, S., Trush, M. A., and Kensler, T. W. (2006) Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion. Arch. Biochem. Biophys. 454, 7-15 (Pubitemid 44427746)
    • (2006) Archives of Biochemistry and Biophysics , vol.454 , Issue.1 , pp. 7-15
    • Osburn, W.O.1    Wakabayashi, N.2    Misra, V.3    Nilles, T.4    Biswal, S.5    Trush, M.A.6    Kensler, T.W.7
  • 80
    • 53049086565 scopus 로고    scopus 로고
    • BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite
    • Reichard, J. F., Sartor, M. A., and Puga, A. (2008) BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite. J. Biol. Chem. 283, 22363-22370
    • (2008) J. Biol. Chem. , vol.283 , pp. 22363-22370
    • Reichard, J.F.1    Sartor, M.A.2    Puga, A.3
  • 82
    • 0141621061 scopus 로고    scopus 로고
    • NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons
    • DOI 10.1074/jbc.M305204200
    • Lee, J. M., Shih, A. Y., Murphy, T. H., and Johnson, J. A. (2003) NF-E2- related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons. J. Biol. Chem. 278, 37948-37956 (Pubitemid 37175325)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.39 , pp. 37948-37956
    • Lee, J.-M.1    Shih, A.Y.2    Murphy, T.H.3    Johnson, J.A.4
  • 83
    • 80052713227 scopus 로고    scopus 로고
    • Novel function of transcription factor Nrf2 as an inhibitor of RON tyrosine kinase receptor-mediated cancer cell invasion
    • Thangasamy, A., Rogge, J., Krishnegowda, N. K., Freeman, J. W., and Ammanamanchi, S. (2011) Novel function of transcription factor Nrf2 as an inhibitor of RON tyrosine kinase receptor-mediated cancer cell invasion. J. Biol. Chem. 286, 32115-32122
    • (2011) J. Biol. Chem. , vol.286 , pp. 32115-32122
    • Thangasamy, A.1    Rogge, J.2    Krishnegowda, N.K.3    Freeman, J.W.4    Ammanamanchi, S.5
  • 84
    • 0027922810 scopus 로고
    • Roel of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction
    • Nebert, D. W., Puga, A., and Vasiliou, V. (1993) Role of the Ah receptor and the dioxin-inducible (Ah) gene battery in toxicity, cancer, and signal transduction. Ann. N.Y. Acad. Sci. 685, 624-640 (Pubitemid 23238548)
    • (1993) Annals of the New York Academy of Sciences , vol.685 , pp. 624-640
    • Nebert, D.W.1    Puga, A.2    Vasiliou, V.3
  • 85
    • 0033990325 scopus 로고    scopus 로고
    • Role of the aromatic hydrocarbon receptor and (Ah) gene battery in the oxidative stress response, cell cycle control, and apoptosis
    • Nebert, D. W., Roe, A. L., Dieter, M. Z., Solis, W. A., Yang, Y., and Dalton, T. P. (2000) Role of the aromatic hydrocarbon receptor and (Ah) gene battery in the oxidative stress response, cell cycle control, and apoptosis. Biochem. Pharmacol. 59, 65-85
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 65-85
    • Nebert, D.W.1    Roe, A.L.2    Dieter, M.Z.3    Solis, W.A.4    Yang, Y.5    Dalton, T.P.6
  • 86
    • 77958093867 scopus 로고    scopus 로고
    • Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach
    • Kalthoff, S., Ehmer, U., Freiberg, N., Manns, M. P., and Strassburg, C. P. (2010) Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach. Gastroenterology 139, 1699-1710, 1710.e1-2
    • (2010) Gastroenterology , vol.139
    • Kalthoff, S.1    Ehmer, U.2    Freiberg, N.3    Manns, M.P.4    Strassburg, C.P.5
  • 87
    • 77949901726 scopus 로고    scopus 로고
    • Interaction between oxidative stress sensor Nrf2 and xenobiotic-activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDP-glucuronosyltransferase 1A10
    • Kalthoff, S., Ehmer, U., Freiberg, N., Manns, M. P., and Strassburg, C. P. (2010) Interaction between oxidative stress sensor Nrf2 and xenobiotic-activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDP-glucuronosyltransferase 1A10. J. Biol. Chem. 285, 5993-6002
    • (2010) J. Biol. Chem. , vol.285 , pp. 5993-6002
    • Kalthoff, S.1    Ehmer, U.2    Freiberg, N.3    Manns, M.P.4    Strassburg, C.P.5
  • 88
    • 79954954342 scopus 로고    scopus 로고
    • Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine
    • Shimamoto, K., Dewa, Y., Ishii, Y., Kemmochi, S., Taniai, E., Hayashi, H., Imaoka, M., Morita, R., Kuwata, K., Suzuki, K., Shibutani, M., and Mitsumori, K. (2011) Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine. Toxicology 283, 109-117
    • (2011) Toxicology , vol.283 , pp. 109-117
    • Shimamoto, K.1    Dewa, Y.2    Ishii, Y.3    Kemmochi, S.4    Taniai, E.5    Hayashi, H.6    Imaoka, M.7    Morita, R.8    Kuwata, K.9    Suzuki, K.10    Shibutani, M.11    Mitsumori, K.12
  • 89
    • 0034752461 scopus 로고    scopus 로고
    • Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
    • DOI 10.1046/j.1365-2443.2001.00469.x
    • Katoh, Y., Itoh, K., Yoshida, E., Miyagishi, M., Fukamizu, A., and Yamamoto, M. (2001) Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells 6, 857-868 (Pubitemid 33019739)
    • (2001) Genes to Cells , vol.6 , Issue.10 , pp. 857-868
    • Katoh, Y.1    Itoh, K.2    Yoshida, E.3    Miyagishi, M.4    Fukamizu, A.5    Yamamoto, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.