-
2
-
-
77958184624
-
Whats new in the treatment of cocaine addiction
-
Kampman KM. What's new in the treatment of cocaine addiction? Curr. Psychiatry Rep. 12(5), 441-447 (2010).
-
(2010)
Curr. Psychiatry Rep.
, vol.12
, Issue.5
, pp. 441-447
-
-
Kampman, K.M.1
-
3
-
-
41649099858
-
New treatments for cocaine dependence: A focused review
-
DOI 10.1017/S1461145707008097, PII S1461145707008097
-
Karila L, Gorelick D, Weinstein A et al. New treatments for cocaine dependence: a focused review. Int. J. Neuropsychopharmacology 11(3), 425-438 (2008). (Pubitemid 351482505)
-
(2008)
International Journal of Neuropsychopharmacology
, vol.11
, Issue.3
, pp. 425-438
-
-
Karila, L.1
Gorelick, D.2
Weinstein, A.3
Noble, F.4
Benyamina, A.5
Coscas, S.6
Blecha, L.7
Lowenstein, W.8
Martinot, J.L.9
Reynaud, M.10
Lepine, J.P.11
-
4
-
-
77951466967
-
Review of treatment for cocaine dependence
-
Penberthy JK, Ait-Daoud N, Vaughan M, Fanning T. Review of treatment for cocaine dependence. Curr. Drug Abuse Rev. 3(1), 49-62 (2010).
-
(2010)
Curr. Drug Abuse Rev.
, vol.3
, Issue.1
, pp. 49-62
-
-
Penberthy, J.K.1
Ait-Daoud, N.2
Vaughan, M.3
Fanning, T.4
-
5
-
-
16044371587
-
Efficacy of a therapeutic cocaine vaccine in rodent models
-
DOI 10.1038/nm1096-1129
-
Fox BS, Kantak KM, Edwards MA et al. Efficacy of a therapeutic cocaine vaccine in rodent models. Nat. Med. 2(10), 1129-1132 (1996). (Pubitemid 26338633)
-
(1996)
Nature Medicine
, vol.2
, Issue.10
, pp. 1129-1132
-
-
Fox, B.S.1
Kantak, K.M.2
Edwards, M.A.3
Black, K.M.4
Bollinger, B.K.5
Botka, A.J.6
French, T.L.7
Thompson, T.L.8
Schad, V.C.9
Greenstein, J.L.10
Gefter, M.L.11
Exley, M.A.12
Swain, P.A.13
Briner, T.J.14
-
6
-
-
0034705038
-
Cocaine vaccines: Antibody protection against relapse in a rat model
-
DOI 10.1073/pnas.97.11.6202
-
Carrera MR, Ashley JA, Zhou B, Wirsching P, Koob GF, Janda KD. Cocaine vaccines: antibody protection against relapse in a rat model. Proc. Natl Acad. Sci. USA 97(11), 6202-6206 (2000). (Pubitemid 30367547)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.11
, pp. 6202-6206
-
-
Carrera, M.R.A.1
Ashley, J.A.2
Zhou, B.3
Wirsching, P.4
Koob, G.F.5
Janda, K.D.6
-
7
-
-
0034092902
-
Evaluation of anti-cocaine antibodies and a cocaine vaccine in a rat self-administration model
-
Kantak KM, Collins SL, Lipman EG, Bond J, Giovanoni K, Fox BS. Evaluation of anticocaine antibodies and a cocaine vaccine in a rat self-administration model. Psychopharmacology 148(3), 251-262 (2000). (Pubitemid 30136732)
-
(2000)
Psychopharmacology
, vol.148
, Issue.3
, pp. 251-262
-
-
Kantak, K.M.1
Collins, S.L.2
Lipman, E.G.3
Bond, J.4
Giovanoni, K.5
Fox, B.S.6
-
8
-
-
0037081517
-
Human therapeutic cocaine vaccine: Safety and immunogenicity
-
DOI 10.1016/S0264-410X(01)00425-X, PII S0264410X0100425X
-
Kosten TR, Rosen M, Bond J et al. Human therapeutic cocaine vaccine: safety and immunogenicity. Vaccine 20(7-8), 1196-1204 (2002). (Pubitemid 34135957)
-
(2002)
Vaccine
, vol.20
, Issue.7-8
, pp. 1196-1204
-
-
Kosten, T.R.1
Rosen, M.2
Bond, J.3
Settles, M.4
Roberts, J.St.C.5
Shields, J.6
Jack, L.7
Fox, B.8
-
9
-
-
71349084953
-
Cocaine-specific antibodies blunt the subjective effects of smoked cocaine in humans
-
Haney M, Gunderson EW, Jiang H, Collins ED, Foltin RW. Cocaine-specific antibodies blunt the subjective effects of smoked cocaine in humans. Biol. Psychiatry 67(1), 59-65 (2010).
-
(2010)
Biol. Psychiatry
, vol.67
, Issue.1
, pp. 59-65
-
-
Haney, M.1
Gunderson, E.W.2
Jiang, H.3
Collins, E.D.4
Foltin, R.W.5
-
10
-
-
70349690285
-
Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: A randomized double blind placebo-controlled efficacy trial
-
Martell BA, Orson FM, Poling J et al. Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double blind, placebo-controlled efficacy trial. Arch. Gen. Psychiatry 66(10), 1116-1123 (2009).
-
(2009)
Arch. Gen. Psychiatry
, vol.66
, Issue.10
, pp. 1116-1123
-
-
Martell, B.A.1
Orson, F.M.2
Poling, J.3
-
11
-
-
79952195569
-
Cocaine analog coupled to disrupted adenovirus: A vaccine strategy to evoke high-titer immunity against addictive drugs
-
Hicks MJ, De BP, Rosenberg JB et al. Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs. Mol. Ther. 19(3), 612-619 (2011).
-
(2011)
Mol. Ther.
, vol.19
, Issue.3
, pp. 612-619
-
-
Hicks, M.J.1
De, B.P.2
Rosenberg, J.B.3
-
12
-
-
33845889554
-
A chimeric human/murine anticocaine monoclonal antibody inhibits the distribution of cocaine to the brain in mice
-
DOI 10.1124/jpet.106.111781
-
Norman AB, Tabet MR, Norman MK, Buesing WR, Pesce AJ, Ball WJ. A chimeric human/murine anticocaine monoclonal antibody inhibits the distribution of cocaine to the brain in mice. J. Pharmacol. Exp. Ther. 320(1), 145-153 (2007). (Pubitemid 46025729)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.320
, Issue.1
, pp. 145-153
-
-
Norman, A.B.1
Tabet, M.R.2
Norman, M.K.3
Buesing, W.R.4
Pesce, A.J.5
Ball, W.J.6
-
13
-
-
62449333563
-
The effect of a chimeric human/murine anticocaine monoclonal antibody on cocaine self-administration in rats
-
Norman A, Norman M, Buesing W, Tabet M, Tsibulsky V, Ball W. The effect of a chimeric human/murine anticocaine monoclonal antibody on cocaine self-administration in rats. J. Pharmacol. Exp. Ther. 328(3), 873-881 (2008).
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.328
, Issue.3
, pp. 873-881
-
-
Norman, A.1
Norman, M.2
Buesing, W.3
Tabet, M.4
Tsibulsky, V.5
Ball, W.6
-
15
-
-
49249135911
-
Pharmacokinetic approaches to treatment of drug addiction
-
Gorelick DA. Pharmacokinetic approaches to treatment of drug addiction. Expert Rev. Clin. Pharmacol. 1(2), 277-290 (2008).
-
(2008)
Expert Rev. Clin. Pharmacol.
, vol.1
, Issue.2
, pp. 277-290
-
-
Gorelick, D.A.1
-
17
-
-
0017664631
-
Hydrolysis of cocaine in human plasma by cholinesterase
-
Stewart DJ, Inaba T, Tang BK, Kalow W. Hydrolysis of cocaine in human plasma by cholinesterase. Life Sci. 20(9), 1557-1563 (1977). (Pubitemid 8118362)
-
(1977)
Life Sciences
, vol.20
, Issue.9
, pp. 1557-1563
-
-
Stewart, D.J.1
Inaba, T.2
Tang, B.K.3
Kalow, W.4
-
18
-
-
0029686495
-
Plasma butylcholinesterase activity and cocaine half-life differ significantly in rhesus and squirrel monkeys
-
DOI 10.1016/0024-3205(96)00392-X
-
Carmona GN, Baum I, Schindler CW et al. Plasma butyrylcholinesterase activity and cocaine half-life differ significantly in rhesus and squirrel monkeys. Life Sci. 59(11), 939-943 (1996). (Pubitemid 26264462)
-
(1996)
Life Sciences
, vol.59
, Issue.11
, pp. 939-943
-
-
Carmona, G.N.1
Baum, I.2
Schindler, C.W.3
Goldberg, S.R.4
Jufer, R.5
Cone, E.6
Slaughter, E.7
Belendiuk, G.W.8
Gorelick, D.A.9
-
19
-
-
0024969418
-
Cocaine complications and pseudocholinesterase
-
Devenyi P. Cocaine complications and pseudocholinesterase. Ann. Intern. Med. 110(2), 167-168 (1989).
-
(1989)
Ann. Intern. Med.
, vol.110
, Issue.2
, pp. 167-168
-
-
Devenyi, P.1
-
20
-
-
0026532220
-
Association between life-threatening cocaine toxicity and plasma cholinesterase activity
-
Hoffman RS, Henry GC, Howland MA, Weisman RS, Weil L, Goldfrank LR. Association between life-threatening cocaine toxicity and plasma cholinesterase activity. Ann. Emerg. Med. 21(3), 247-253 (1992).
-
(1992)
Ann. Emerg. Med.
, vol.21
, Issue.3
, pp. 247-253
-
-
Hoffman, R.S.1
Henry, G.C.2
Howland, M.A.3
Weisman, R.S.4
Weil, L.5
Goldfrank, L.R.6
-
21
-
-
0018366423
-
Cocaine and succinylcholine sensitivity: A new caution
-
Jatlow P, Barash PG, Van Dyke C, Radding J, Byck R. Cocaine and succinylcholine sensitivity: a new caution. Anesth. Analg. 58(3), 235-238 (1979). (Pubitemid 9188773)
-
(1979)
Anesthesia and Analgesia
, vol.58
, Issue.3
, pp. 235-238
-
-
Jatlow, P.1
Barash, P.G.2
Van Dyke, C.3
-
22
-
-
0027450866
-
Medical complications of cocaine: Possible relationship to low plasma cholinesterase enzyme
-
DOI 10.1016/0002-8703(93)90122-P
-
Om A, Ellahham S, Ornato JP et al. Medical complications of cocaine: possible relationship to low plasma cholinesterase enzyme. Am. Heart J. 125(4), 1114-1117 (1993). (Pubitemid 23117346)
-
(1993)
American Heart Journal
, vol.125
, Issue.4
, pp. 1114-1117
-
-
Om, A.1
Ellahham, S.2
Ornato, J.P.3
Picone, C.4
Theogaraj, J.5
Corretjer, G.P.6
Vetrovec, G.W.7
-
23
-
-
0027250161
-
Gender-related differences in cocaine toxicity in the rat
-
Morishima HO, Abe Y, Matsuo M, Akiba K, Masaoka T, Cooper TB. Gender-related differences in cocaine toxicity in the rat. J. Lab. Clin. Med. 122(2), 157-163 (1993). (Pubitemid 23239146)
-
(1993)
Journal of Laboratory and Clinical Medicine
, vol.122
, Issue.2
, pp. 157-163
-
-
Morishima, H.O.1
Abe, Y.2
Matsuo, M.3
Akiba, K.4
Masaoka, T.5
Cooper, T.B.6
-
24
-
-
0030007690
-
Administration of purified human plasma cholinesterase protects against cocaine toxicity in mice
-
Hoffman RS, Morasco R, Goldfrank LR. Administration of purified human plasma cholinesterase protects against cocaine toxicity in mice. J. Toxicol. Clin. Toxicol. 34(3), 259-266 (1996). (Pubitemid 26198099)
-
(1996)
Journal of Toxicology - Clinical Toxicology
, vol.34
, Issue.3
, pp. 259-266
-
-
Hoffman, R.S.1
Morasco, R.2
Goldfrank, L.R.3
-
25
-
-
56049111361
-
Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice
-
Duysen EG, Li B, Carlson M et al. Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice. Basic Clin. Pharmacol. Toxicol. 103(6), 514-521 (2008).
-
(2008)
Basic Clin. Pharmacol. Toxicol.
, vol.103
, Issue.6
, pp. 514-521
-
-
Duysen, E.G.1
Li, B.2
Carlson, M.3
-
26
-
-
0025857316
-
Prolongation of cocaine effect
-
Herschman Z, Aaron C. Prolongation of cocaine effect. Anesthesiology 74(3), 631-632 (1991).
-
(1991)
Anesthesiology
, vol.74
, Issue.3
, pp. 631-632
-
-
Herschman, Z.1
Aaron, C.2
-
27
-
-
0030070328
-
Effect of cocaine metabolites on behavior: Possible neuroendocrine mechanisms
-
DOI 10.1016/0361-9230(95)02040-3
-
Schuelke GS, Konkol RJ, Terry LC, Madden JA. Effect of cocaine metabolites on behavior: possible neuroendocrine mechanisms. Brain Res. Bull. 39(1), 43-48 (1996). (Pubitemid 26002146)
-
(1996)
Brain Research Bulletin
, vol.39
, Issue.1
, pp. 43-48
-
-
Schuelke, G.S.1
Konkol, R.J.2
Terry, L.C.3
Madden, J.A.4
-
28
-
-
0027193032
-
Antibody-catalyzed degradation of cocaine
-
Landry DW, Zhao K, Yang GX, Glickman M, Georgiadis TM. Antibody-catalyzed degradation of cocaine. Science 259(5103), 1899-1901 (1993). (Pubitemid 23124461)
-
(1993)
Science
, vol.259
, Issue.5103
, pp. 1899-1901
-
-
Landry, D.W.1
Zhao, K.2
Yang, G.X.-Q.3
Glickman, M.4
Georgiadis, T.M.5
-
29
-
-
0030735986
-
Enhancing cocaine metabolism with butyrylcholinesterase as a treatment strategy
-
DOI 10.1016/S0376-8716(97)00119-1, PII S0376871697001191
-
Gorelick DA. Enhancing cocaine metabolism with butyrylcholinesterase as a treatment strategy. Drug Alcohol Depend. 48(3), 159-165 (1997). (Pubitemid 27526022)
-
(1997)
Drug and Alcohol Dependence
, vol.48
, Issue.3
, pp. 159-165
-
-
Gorelick, D.A.1
-
30
-
-
0035937713
-
Predicted michaelis-menten complexes of cocaine-butyrylcholinesterase engineering effective butyrylcholinesterase mutants for cocaine detoxication
-
Sun H, El Yazal J, Lockridge O, Schopfer LM, Brimijoin S, Pang YP. Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase. Engineering effective butyrylcholinesterase mutants for cocaine detoxication. J. Biol. Chem. 276(12), 9330-9336 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.12
, pp. 9330-9336
-
-
Sun, H.1
El Yazal, J.2
Lockridge, O.3
Schopfer, L.M.4
Brimijoin, S.5
Pang, Y.P.6
-
31
-
-
0034097143
-
Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1
-
DOI 10.1128/AEM.66.3.904-908.2000
-
Bresler MM, Rosser SJ, Basran A, Bruce NC. Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1. Appl. Environ. Microbiol. 66(3), 904-908 (2000). (Pubitemid 30130004)
-
(2000)
Applied and Environmental Microbiology
, vol.66
, Issue.3
, pp. 904-908
-
-
Bresler, M.M.1
Rosser, S.J.2
Basran, A.3
Bruce, N.C.4
-
32
-
-
0022992561
-
Catalytic antibodies
-
Tramontano A, Janda KD, Lerner RA. Catalytic antibodies. Science 234(4783), 1566-1570 (1986). (Pubitemid 17125281)
-
(1986)
Science
, vol.234
, Issue.4783
, pp. 1566-1570
-
-
Tramontano, A.1
Janda, K.D.2
Lerner, R.A.3
-
33
-
-
0030018803
-
Anti-cocaine catalytic antibodies: A synthetic approach to improved antibody diversity
-
DOI 10.1021/ja953077+
-
Yang G, Chun J, Arakawa-Uramoto H et al. Anticocaine catalytic antibodies: a synthetic approach to improved antibody diversity. J. Am. Chem. Soc. 118, 5881-5890 (1996). (Pubitemid 26236808)
-
(1996)
Journal of the American Chemical Society
, vol.118
, Issue.25
, pp. 5881-5890
-
-
Yang, G.1
Chun, J.2
Arakawa-Uramoto, H.3
Wang, X.4
Gawinowicz, M.A.5
Zhao, K.6
Landry, D.W.7
-
34
-
-
13144283624
-
A catalytic antibody against cocaine prevents cocaine's reinforcing and toxic effects in rats
-
DOI 10.1073/pnas.95.17.10176
-
Mets B, Winger G, Cabrera C et al. A catalytic antibody against cocaine prevents cocaine's reinforcing and toxic effects in rats. Proc. Natl Acad. Sci. USA 95(17), 10176-10181 (1998). (Pubitemid 28415314)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.17
, pp. 10176-10181
-
-
Mets, B.1
Winger, G.2
Cabrera, C.3
Seo, S.4
Jamdar, S.5
Yang, G.6
Zhao, K.7
Briscoe, R.J.8
Almonte, R.9
Woods, J.H.10
Landry, D.W.11
-
35
-
-
0033724861
-
Natural and artificial enzymes against cocaine I monoclonal antibody 15A10 and the reinforcing effects of cocaine in rats
-
Baird TJ, Deng SX, Landry DW, Winger G, Woods JH. Natural and artificial enzymes against cocaine. I. Monoclonal antibody 15A10 and the reinforcing effects of cocaine in rats. J. Pharmacol. Exp. Ther. 295(3), 1127-1134 (2000).
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, Issue.3
, pp. 1127-1134
-
-
Baird, T.J.1
Deng, S.X.2
Landry, D.W.3
Winger, G.4
Woods, J.H.5
-
36
-
-
0035038391
-
A catalytic antibody against cocaine attenuates cocaine's cardiovascular effects in mice: A dose and time course analysis
-
DOI 10.1016/S1567-5769(01)00054-6, PII S1567576901000546
-
Briscoe RJ, Jeanville PM, Cabrera C, Baird TJ, Woods JH, Landry DW. A catalytic antibody against cocaine attenuates cocaine's cardiovascular effects in mice: a dose and time course analysis. Int. Immunopharmacol. 1(6), 1189-1198 (2001). (Pubitemid 32434434)
-
(2001)
International Immunopharmacology
, vol.1
, Issue.6
, pp. 1189-1198
-
-
Briscoe, R.J.1
Jeanville, P.M.2
Cabrera, C.3
Baird, T.J.4
Woods, J.H.5
Landry, D.W.6
-
37
-
-
1342282231
-
Substrate-assisted antibody catalysis
-
Deng S, Bharat N, de Prada P, Landry DW. Substrate-assisted antibody catalysis. Org. Biomol. Chem. 2(3), 288-290 (2004).
-
(2004)
Org. Biomol. Chem.
, vol.2
, Issue.3
, pp. 288-290
-
-
Deng, S.1
Bharat, N.2
De Prada, P.3
Landry, D.W.4
-
38
-
-
0037051638
-
Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration
-
DOI 10.1021/ja012376y
-
Isomura S, Hoffman TZ, Wirsching P, Janda KD. Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration. J. Am. Chem. Soc. 124(14), 3661-3668 (2002). (Pubitemid 34407890)
-
(2002)
Journal of the American Chemical Society
, vol.124
, Issue.14
, pp. 3661-3668
-
-
Isomura, S.1
Hoffman, T.Z.2
Wirsching, P.3
Janda, K.D.4
-
39
-
-
0035931346
-
Cocaine catalytic antibodies: The primary importance of linker effects
-
DOI 10.1016/S0960-894X(00)00659-4, PII S0960894X00006594
-
Matsushita M, Hoffman TZ, Ashley JA, Zhou B, Wirsching P, Janda KD. Cocaine catalytic antibodies: the primary importance of linker effects. Bioorg. Med. Chem. Lett. 11(2), 87-90 (2001). (Pubitemid 32099616)
-
(2001)
Bioorganic and Medicinal Chemistry Letters
, vol.11
, Issue.2
, pp. 87-90
-
-
Matsushita, M.1
Hoffman, T.Z.2
Ashley, J.A.3
Zhou, B.4
Wirsching, P.5
Janda, K.D.6
-
40
-
-
32044465761
-
Complete reaction cycle of a cocaine catalytic antibody at atomic resolution
-
DOI 10.1016/j.str.2005.10.014, PII S0969212606000505
-
Zhu X, Dickerson TJ, Rogers CJ et al. Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure 14(2), 205-216 (2006). (Pubitemid 43202010)
-
(2006)
Structure
, vol.14
, Issue.2
, pp. 205-216
-
-
Zhu, X.1
Dickerson, T.J.2
Rogers, C.J.3
Kaufmann, G.F.4
Mee, J.M.5
McKenzie, K.M.6
Janda, K.D.7
Wilson, I.A.8
-
41
-
-
33845662807
-
Identification and Characterization of Single Chain Anti-cocaine Catalytic Antibodies
-
DOI 10.1016/j.jmb.2006.10.031, PII S0022283606014094
-
McKenzie KM, Mee JM, Rogers CJ, Hixon MS, Kaufmann GF, Janda KD. Identification and characterization of single chain anticocaine catalytic antibodies. J. Mol. Biol. 365(3), 722-731 (2007). (Pubitemid 44960359)
-
(2007)
Journal of Molecular Biology
, vol.365
, Issue.3
, pp. 722-731
-
-
McKenzie, K.M.1
Mee, J.M.2
Rogers, C.J.3
Hixon, M.S.4
Kaufmann, G.F.5
Janda, K.D.6
-
43
-
-
0025962236
-
Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice
-
Ashani Y, Shapira S, Levy D, Wolfe AD, Doctor BP, Raveh L. Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice. Biochem. Pharmacol. 41(1), 37-41 (1991).
-
(1991)
Biochem. Pharmacol.
, vol.41
, Issue.1
, pp. 37-41
-
-
Ashani, Y.1
Shapira, S.2
Levy, D.3
Wolfe, A.D.4
Doctor, B.P.5
Raveh, L.6
-
44
-
-
0027427279
-
Prevention of soman-induced cognitive deficits by pretreatment with human butyrylcholinesterase in rats
-
Brandeis R, Raveh L, Grunwald J, Cohen E, Ashani Y. Prevention of soman-induced cognitive deficits by pretreatment with human butyrylcholinesterase in rats. Pharmacol. Biochem. Behav. 46(4), 889-896 (1993).
-
(1993)
Pharmacol. Biochem. Behav.
, vol.46
, Issue.4
, pp. 889-896
-
-
Brandeis, R.1
Raveh, L.2
Grunwald, J.3
Cohen, E.4
Ashani, Y.5
-
45
-
-
0025884479
-
Enzymes as pretreatment drugs for organophosphate toxicity
-
Doctor BP, Raveh L, Wolfe AD, Maxwell DM, Ashani Y. Enzymes as pretreatment drugs for organophosphate toxicity. Neurosci. Biobehav. Rev. 15(1), 123-128 (1991).
-
(1991)
Neurosci. Biobehav. Rev.
, vol.15
, Issue.1
, pp. 123-128
-
-
Doctor, B.P.1
Raveh, L.2
Wolfe, A.D.3
Maxwell, D.M.4
Ashani, Y.5
-
46
-
-
0027053644
-
Use of cholinesterases as pretreatment drugs for the protection of rhesus monkeys against soman toxicity
-
DOI 10.1016/0041-008X(92)90236-L
-
Wolfe AD, Blick DW, Murphy MR et al. Use of cholinesterases as pretreatment drugs for the protection of rhesus monkeys against soman toxicity. Toxicol. Appl. Pharmacol. 117(2), 189-193 (1992). (Pubitemid 23009714)
-
(1992)
Toxicology and Applied Pharmacology
, vol.117
, Issue.2
, pp. 189-193
-
-
Wolfe, A.D.1
Blick, D.W.2
Murphy, M.R.3
Miller, S.A.4
Gentry, M.K.5
Hartgraves, S.L.6
Doctor, B.P.7
-
47
-
-
35348893697
-
Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning
-
DOI 10.1073/pnas.0702756104
-
Huang Y-J, Huang Y, Baldassarre H et al. Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning. Proc. Natl Acad. Sci. USA 104(34), 13603-13608 (2007). (Pubitemid 350010655)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.34
, pp. 13603-13608
-
-
Huang, Y.-J.1
Huang, Y.2
Baldassarre, H.3
Wang, B.4
Lazaris, A.5
Leduc, M.6
Bilodeau, A.S.7
Bellemare, A.8
Cote, M.9
Herskovits, P.10
Touati, M.11
Turcotte, C.12
Valeanu, L.13
Lemee, N.14
Wilgus, H.15
Begin, I.16
Bhatia, B.17
Rao, K.18
Neveu, N.19
Brochu, E.20
Pierson, J.21
Hockley, D.K.22
Cerasoli, D.M.23
Lenz, D.E.24
Karatzas, C.N.25
Langermann, S.26
more..
-
48
-
-
27544478065
-
Large scale purification of butyrylcholineserase from human plasma suitable for injection into monkeys: A potential new therapeutic for protection against cocaine and nerve agent toxicity
-
nihms5095
-
Lockridge O, Schopfer LM, Winger G, Woods JH. Large scale purification of butyrylcholineserase from human plasma suitable for injection into monkeys: a potential new therapeutic for protection against cocaine and nerve agent toxicity. J. Med. Chem. Biol. Radiol. Def. 3, nihms5095 (2005).
-
(2005)
J. Med. Chem. Biol. Radiol. Def.
, vol.3
-
-
Lockridge, O.1
Schopfer, L.M.2
Winger, G.3
Woods, J.H.4
-
49
-
-
0031214055
-
Therapeutic use of butyrylcholinesterase for cocaine intoxication
-
Mattes CE, Lynch TJ, Singh A et al. Therapeutic use of butyrylcholinesterase for cocaine intoxication. Toxicol. Appl. Pharmacol. 145(2), 372-380 (1997).
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.145
, Issue.2
, pp. 72-380
-
-
Mattes, C.E.1
Lynch, T.J.2
Singh, A.3
-
50
-
-
0031839079
-
The influence of plasma butyrylcholinesterase concentration on the in vitro hydrolysis of cocaine in human plasma
-
DOI 10.1002/(SICI)1099-081X(199807)19:5<309::AID-BDD108>3.0.CO;2-9
-
Browne SP, Slaughter EA, Couch RA, Rudnic EM, McLean AM. The influence of plasma butyrylcholinesterase concentration on the in vitro hydrolysis of cocaine in human plasma. Biopharm. Drug Dispos. 19(5), 309-314 (1998). (Pubitemid 28313930)
-
(1998)
Biopharmaceutics and Drug Disposition
, vol.19
, Issue.5
, pp. 309-314
-
-
Browne, S.P.1
Slaughter, E.A.2
Couch, R.A.3
Rudnic, E.M.4
McLean, A.M.5
-
51
-
-
0031822393
-
Attenuation of cocaine-induced locomotor activity by butyrylcholinesterase
-
DOI 10.1037//1064-1297.6.3.274
-
Carmona GN, Schindler CW, Shoaib M et al. Attenuation of cocaine-induced locomotor activity by butyrylcholinesterase. Exp. Clin. Psychopharmacol. 6(3), 274-279 (1998). (Pubitemid 28393945)
-
(1998)
Experimental and Clinical Psychopharmacology
, vol.6
, Issue.3
, pp. 274-279
-
-
Carmona, G.N.1
Schindler, C.W.2
Shoaib, M.3
Jufer, R.4
Cone, E.J.5
Goldberg, S.R.6
Greig, N.H.7
Yu, Q.-S.8
Gorelick, D.A.9
-
52
-
-
22144498814
-
Intravenous butyrylcholinesterase administration and plasma and brain levels of cocaine and metabolites in rats
-
DOI 10.1016/j.ejphar.2005.05.013, PII S0014299905005522
-
Carmona GN, Schindler CW, Greig NH et al. Intravenous butyrylcholinesterase administration and plasma and brain levels of cocaine and metabolites in rats. Eur. J. Pharmacol. 517(3), 186-190 (2005). (Pubitemid 40977894)
-
(2005)
European Journal of Pharmacology
, vol.517
, Issue.3
, pp. 186-190
-
-
Carmona, G.N.1
Schindler, C.W.2
Greig, N.H.3
Holloway, H.W.4
Jufer, R.A.5
Cone, E.J.6
Gorelick, D.A.7
-
53
-
-
0036263325
-
Characterization of butyrylcholinesterase antagonism of cocaine-induced hyperactivity
-
DOI 10.1124/dmd.30.6.716
-
Koetzner L, Woods JH. Characterization of butyrylcholinesterase antagonism of cocaine-induced hyperactivity. Drug Metab. Dispos. 30(6), 716-723 (2002). (Pubitemid 34579107)
-
(2002)
Drug Metabolism and Disposition
, vol.30
, Issue.6
, pp. 716-723
-
-
Koetzner, L.1
Woods, J.H.2
-
54
-
-
0031213567
-
Cocaine detoxification by human plasma butyrylcholinesterase
-
DOI 10.1006/taap.1997.8187
-
Lynch TJ, Mattes CE, Singh A, Bradley RM, Brady RO, Dretchen KL. Cocaine detoxification by human plasma butyrylcholinesterase. Toxicol. Appl. Pharmacol. 145(2), 363-371 (1997). (Pubitemid 27346526)
-
(1997)
Toxicology and Applied Pharmacology
, vol.145
, Issue.2
, pp. 363-371
-
-
Lynch, T.J.1
Mattes, C.E.2
Singh, A.3
Bradley, R.M.4
Brady, R.O.5
Dretchen, K.L.6
-
55
-
-
0036070598
-
Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity
-
DOI 10.1124/jpet.102.033746
-
Duysen EG, Bartels CF, Lockridge O. Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity. J. Pharmacol. Exp. Ther. 302(2), 751-758 (2002). (Pubitemid 34787244)
-
(2002)
Journal of Pharmacology and Experimental Therapeutics
, vol.302
, Issue.2
, pp. 751-758
-
-
Duysen, E.G.1
Bartels, C.F.2
Lockridge, O.3
-
56
-
-
51749096409
-
Most efficient cocaine hydrolase designed by virtual screening of transition states
-
Zheng F, Yang W, Ko M-C et al. Most efficient cocaine hydrolase designed by virtual screening of transition states. J. Am. Chem. Soc. 130(36), 12148-12155 (2008).
-
(2008)
J. Am. Chem. Soc.
, vol.130
, Issue.36
, pp. 12148-12155
-
-
Zheng, F.1
Yang, W.2
Ko, M.-C.3
-
57
-
-
0036077314
-
Re-engineering butyrylcholinesterase as a cocaine hydrolase
-
DOI 10.1124/mol.62.2.220
-
Sun H, Pang Y-P, Lockridge O, Brimijoin S. Re-engineering butyrylcholinesterase as a cocaine hydrolase. Mol. Pharmacol. 62(2), 220-224 (2002). (Pubitemid 34804100)
-
(2002)
Molecular Pharmacology
, vol.62
, Issue.2
, pp. 220-224
-
-
Sun, H.1
Pang, Y.-P.2
Lockridge, O.3
Brimijoin, S.4
-
58
-
-
0036073873
-
Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase
-
DOI 10.1124/jpet.302.2.710
-
Sun H, Shen ML, Pang Y-P, Lockridge O, Brimijoin S. Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase. J. Pharmacol. Exp. Ther. 302(2), 710-716 (2002). (Pubitemid 34787239)
-
(2002)
Journal of Pharmacology and Experimental Therapeutics
, vol.302
, Issue.2
, pp. 710-716
-
-
Sun, H.1
Shen, M.L.2
Pang, Y.-P.3
Lockridge, O.4
Brimijoin, S.5
-
59
-
-
4243193692
-
An engineered cocaine hydrolase blunts and reverses cardiovascular responses to cocaine in rats
-
DOI 10.1124/jpet.104.068122
-
Gao Y, Brimijoin S. An engineered cocaine hydrolase blunts and reverses cardiovascular responses to cocaine in rats. J. Pharmacol. Exp. Ther. 310(3), 1046-1052 (2004). (Pubitemid 39108926)
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.310
, Issue.3
, pp. 1046-1052
-
-
Gao, Y.1
Brimijoin, S.2
-
60
-
-
50649125211
-
An albumin-butyrylcholinesterase for cocaine toxicity and addiction: Catalytic and pharmacokinetic properties
-
Gao Y, Lafleur D, Shah R, Zhao Q, Singh M, Brimijoin S. An albumin-butyrylcholinesterase for cocaine toxicity and addiction: catalytic and pharmacokinetic properties. Chem. Biol. Interact. 175(1-3), 83-87 (2008).
-
(2008)
Chem. Biol. Interact.
, vol.175
, Issue.1-3
, pp. 83-87
-
-
Gao, Y.1
Lafleur, D.2
Shah, R.3
Zhao, Q.4
Singh, M.5
Brimijoin, S.6
-
61
-
-
4243179662
-
Application of directed evolution technology to optimize the cocaine hydrolase activity of human butyrylcholinesterase
-
Pancock JD, Pecht G, Mosko M, Lockridge O, Watkins JD. Application of directed evolution technology to optimize the cocaine hydrolase activity of human butyrylcholinesterase. FASEB J. 17, A565 (2003).
-
(2003)
FASEB J.
, vol.17
-
-
Pancock, J.D.1
Pecht, G.2
Mosko, M.3
Lockridge, O.4
Watkins, J.D.5
-
62
-
-
11244266133
-
Gene transfer of cocaine hydrolase suppresses cardiovascular responses to cocaine in rats
-
DOI 10.1124/mol.104.006924
-
Gao Y, Atanasova E, Sui N, Pancook JD, Watkins JD, Brimijoin S. Gene transfer of cocaine hydrolase suppresses cardiovascular responses to cocaine in rats. Mol. Pharmacol. 67(1), 204-211 (2005). (Pubitemid 40069980)
-
(2005)
Molecular Pharmacology
, vol.67
, Issue.1
, pp. 204-211
-
-
Gao, Y.1
Atanasova, E.2
Sui, N.3
Pancook, J.D.4
Watkins, J.D.5
Brimijoin, S.6
-
63
-
-
77955517250
-
Characterization of a high-activity mutant of human butyrylcholinesterase against -cocaine
-
Yang W, Xue L, Fang L, Chen X, Zhan C-G. Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine. Chem. Biol. Interact. 187(1-3), 148-152 (2010).
-
(2010)
Chem. Biol. Interact.
, vol.187
, Issue.1-3
, pp. 148-152
-
-
Yang, W.1
Xue, L.2
Fang, L.3
Chen, X.4
Zhan, C.-G.5
-
64
-
-
77954566230
-
The concept of pharmacologic cocaine interception as a treatment for drug abuse
-
Gao Y, Orson FM, Kinsey B, Kosten T, Brimijoin S. The concept of pharmacologic cocaine interception as a treatment for drug abuse. Chem. Biol. Interact. 187(1-3), 421-424 (2010).
-
(2010)
Chem. Biol. Interact.
, vol.187
, Issue.1-3
, pp. 421-424
-
-
Gao, Y.1
Orson, F.M.2
Kinsey, B.3
Kosten, T.4
Brimijoin, S.5
-
65
-
-
84856943879
-
Modification of pharmacokinetic and abuse-related effects of cocaine by human-derived cocaine hydrolase in monkeys
-
In press
-
Schindler CW, Justinova Z, Lafleur D et al. Modification of pharmacokinetic and abuse-related effects of cocaine by human-derived cocaine hydrolase in monkeys. Addiction Biology (2011) (In press).
-
(2011)
Addiction Biology
-
-
Schindler, C.W.1
Justinova, Z.2
Lafleur, D.3
-
66
-
-
48749118846
-
A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats
-
Brimijoin S, Gao Y, Anker JJ et al. A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats. Neuropsychopharmacology 33(11), 2715-2725 (2008).
-
(2008)
Neuropsychopharmacology
, vol.33
, Issue.11
, pp. 2715-2725
-
-
Brimijoin, S.1
Gao, Y.2
Anker, J.J.3
-
67
-
-
79952490297
-
Effects of cocaine hydrolase on cocaine self-administration under a PR schedule and during extended access escalation in rats
-
Carroll ME, Gao Y, Brimijoin S, Anker JJ. Effects of cocaine hydrolase on cocaine self-administration under a PR schedule and during extended access (escalation) in rats. Psychopharmacology 213(4), 817-829 (2011).
-
(2011)
Psychopharmacology
, vol.213
, Issue.4
, pp. 817-829
-
-
Carroll, M.E.1
Gao, Y.2
Brimijoin, S.3
Anker, J.J.4
-
68
-
-
78650634444
-
Design preparation and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine
-
Xue L, Ko M-C, Tong M et al. Design, preparation and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine. Mol. Pharmacol. 79(2), 290-297 (2011).
-
(2011)
Mol. Pharmacol.
, vol.79
, Issue.2
, pp. 290-297
-
-
Xue, L.1
Ko, M.-C.2
Tong, M.3
-
69
-
-
39049178820
-
Viral transduction of cocaine hydrolase in brain reward centers
-
Gao Y, Brimijoin S. Viral transduction of cocaine hydrolase in brain reward centers. Cell. Mol. Neurobiol. 26(4-6), 357-363 (2006).
-
(2006)
Cell. Mol. Neurobiol.
, vol.26
, Issue.4-6
, pp. 357-363
-
-
Gao, Y.1
Brimijoin, S.2
-
70
-
-
67651055389
-
Lasting reduction of cocaine action in neostriatum - A hydrolase gene therapy approach
-
Gao Y, Brimijoin S. Lasting reduction of cocaine action in neostriatum - a hydrolase gene therapy approach. J. Pharmacol. Exp. Ther. 330(2), 449-457 (2009).
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.330
, Issue.2
, pp. 449-457
-
-
Gao, Y.1
Brimijoin, S.2
-
71
-
-
79953004602
-
Gene-delivered butyrylcholinesterase is prophylactic against the toxicity of chemical warfare nerve agents and organophosphorus compounds
-
Parikh K, Duysen EG, Snow B et al. Gene-delivered butyrylcholinesterase is prophylactic against the toxicity of chemical warfare nerve agents and organophosphorus compounds. J. Pharmacol. Exp. Ther. 337(1), 92-101 (2011).
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.337
, Issue.1
, pp. 92-101
-
-
Parikh, K.1
Duysen, E.G.2
Snow, B.3
-
72
-
-
33751097261
-
Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase
-
DOI 10.1124/mol.106.025999
-
Cooper ZD, Narasimhan D, Sunahara RK et al. Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase. Mol. Pharmacol. 70(6), 1885-1891 (2006). (Pubitemid 44771904)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.6
, pp. 1885-1891
-
-
Cooper, Z.D.1
Narasimhan, D.2
Sunahara, R.K.3
Mierzejewski, P.4
Jutkiewicz, E.M.5
Larsen, N.A.6
Wilson, I.A.7
Landry, D.W.8
Woods, J.H.9
-
73
-
-
0036142190
-
Crystal structure of a bacterial cocaine esterase
-
DOI 10.1038/nsb742
-
Larsen NA, Turner JM, Stevens J et al. Crystal structure of a bacterial cocaine esterase. Nat. Struct. Biol. 9(1), 17-21 (2002). (Pubitemid 34049173)
-
(2002)
Nature Structural Biology
, vol.9
, Issue.1
, pp. 17-21
-
-
Larsen, N.A.1
Turner, J.M.2
Stevens, J.3
Rosser, S.J.4
Basran, A.5
Lerner, R.A.6
Bruce, N.C.7
Wilson, I.A.8
-
74
-
-
0037108184
-
Biochemical characterization and structural analysis of a highly proficient cocaine esterase
-
Turner JM, Larsen NA, Basran A et al. Biochemical characterization and structural analysis of a highly proficient cocaine esterase. Biochemistry 41(41), 12297-12307 (2002).
-
(2002)
Biochemistry
, vol.41
, Issue.41
, pp. 12297-12307
-
-
Turner, J.M.1
Larsen, N.A.2
Basran, A.3
-
75
-
-
33846439351
-
Cocaine esterase: Interactions with cocaine and immune responses in mice
-
DOI 10.1124/jpet.106.114223
-
Ko M-C, Bowen LD, Narasimhan D et al. Cocaine esterase: interactions with cocaine and immune responses in mice. J. Pharmacol. Exp. Ther. 320(2), 926-933 (2007). (Pubitemid 46147977)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.320
, Issue.2
, pp. 926-933
-
-
Ko, M.-C.1
Bowen, L.D.2
Narasimhan, D.3
Berlin, A.A.4
Lukacs, N.W.5
Sunahara, R.K.6
Cooper, Z.D.7
Woods, J.H.8
-
76
-
-
61849163341
-
Effects of cocaine esterase following its repeated administration with cocaine in mice
-
Ko M-C, Narasimhan D, Berlin AA, Lukacs NW, Sunahara RK, Woods JH. Effects of cocaine esterase following its repeated administration with cocaine in mice. Drug Alcohol Depend. 101(3), 202-209 (2009).
-
(2009)
Drug Alcohol Depend.
, vol.101
, Issue.3
, pp. 202-209
-
-
Ko, M.-C.1
Narasimhan, D.2
Berlin, A.A.3
Lukacs, N.W.4
Sunahara, R.K.5
Woods, J.H.6
-
77
-
-
68649108141
-
A bacterial cocaine esterase protects against cocaine-induced epileptogenic activity and lethality
-
Jutkiewicz EM, Baladi MG, Cooper ZD, Narasimhan D, Sunahara RK, Woods JH. A bacterial cocaine esterase protects against cocaine-induced epileptogenic activity and lethality. Ann. Emerg. Med. 54(3), 409-420 (2009).
-
(2009)
Ann. Emerg. Med.
, vol.54
, Issue.3
, pp. 409-420
-
-
Jutkiewicz, E.M.1
Baladi, M.G.2
Cooper, Z.D.3
Narasimhan, D.4
Sunahara, R.K.5
Woods, J.H.6
-
78
-
-
73549088941
-
Prevention and reversal by cocaine esterase of cocaine-induced cardiovascular effects in rats
-
Wood SK, Narasimhan D, Cooper Z, Sunahara RK, Woods JH. Prevention and reversal by cocaine esterase of cocaine-induced cardiovascular effects in rats. Drug Alcohol Depend. 106(2-3), 219-229 (2010).
-
(2010)
Drug Alcohol Depend.
, vol.106
, Issue.2-3
, pp. 219-229
-
-
Wood, S.K.1
Narasimhan, D.2
Cooper, Z.3
Sunahara, R.K.4
Woods, J.H.5
-
79
-
-
77955941601
-
Structural analysis of thermostabilizing mutations of cocaine esterase
-
Narasimhan D, Nance MR, Gao D et al. Structural analysis of thermostabilizing mutations of cocaine esterase. Protein Eng. Des. Sel. 23(7), 537-547 (2010).
-
(2010)
Protein Eng. Des. Sel.
, vol.23
, Issue.7
, pp. 537-547
-
-
Narasimhan, D.1
Nance, M.R.2
Gao, D.3
-
80
-
-
70350459860
-
Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats
-
Collins GT, Brim RL, Narasimhan D et al. Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats. J. Pharmacol. Exp. Ther. 331(2), 445-455 (2009).
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.331
, Issue.2
, pp. 445-455
-
-
Collins, G.T.1
Brim, R.L.2
Narasimhan, D.3
-
81
-
-
80053575770
-
Effects of a long-acting mutant bacterial cocaine esterase on acute cocaine toxicity in rats
-
Collins GT, Zaks ME, Cunningham AR et al. Effects of a long-acting mutant bacterial cocaine esterase on acute cocaine toxicity in rats. Drug Alcohol Depend. 118, 158-165 (2011).
-
(2011)
Drug Alcohol Depend.
, vol.118
, pp. 158-165
-
-
Collins, G.T.1
Zaks, M.E.2
Cunningham, A.R.3
-
82
-
-
79952761035
-
Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase
-
Collins GT, Carey KA, Narasimhan D et al. Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase. Neuropsychopharmacology 36(5), 1047-1059 (2011).
-
(2011)
Neuropsychopharmacology
, vol.36
, Issue.5
, pp. 1047-1059
-
-
Collins, G.T.1
Carey, K.A.2
Narasimhan, D.3
-
83
-
-
77950212804
-
A thermally stable form of bacterial cocaine esterase: A potential therapeutic agent for treatment of cocaine abuse
-
Brim RL, Nance MR, Youngstrom DW et al. A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse. Mol. Pharmacol. 77(4), 593-600 (2010).
-
(2010)
Mol. Pharmacol.
, vol.77
, Issue.4
, pp. 593-600
-
-
Brim, R.L.1
Nance, M.R.2
Youngstrom, D.W.3
-
84
-
-
77951030229
-
Safety of administration of human butyrylcholinesterase and its conjugates with soman or VX in rats
-
Genovese RF, Sun W, Johnson CC, Ditargiani RC, Doctor BP, Saxena A. Safety of administration of human butyrylcholinesterase and its conjugates with soman or VX in rats. Basic Clin. Pharmacol. Toxicol. 106(5), 428-434 (2010).
-
(2010)
Basic Clin. Pharmacol. Toxicol.
, vol.106
, Issue.5
, pp. 428-434
-
-
Genovese, R.F.1
Sun, W.2
Johnson, C.C.3
Ditargiani, R.C.4
Doctor, B.P.5
Saxena, A.6
-
85
-
-
22244471748
-
Toward cocaine esterase therapeutics
-
DOI 10.1021/ja053086a
-
Rogers CJ, Mee JM, Kaufmann GF, Dickerson TJ, Janda KD. Toward cocaine esterase therapeutics. J. Am. Chem. Soc. 127(28), 10016-10017 (2005). (Pubitemid 40995442)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.28
, pp. 10016-10017
-
-
Rogers, C.J.1
Mee, J.M.2
Kaufmann, G.F.3
Dickerson, T.J.4
Janda, K.D.5
-
86
-
-
84858335405
-
Long-lasting effects of a PEGylated mutant cocaine esterase CocE on the reinforcing and discriminative stimulus effects of cocaine in rats
-
10.1038/ npp. 2011. 226 Epub ahead of print).
-
Collins GT, Narasimhan D, Cunningham AR et al. Long-lasting effects of a PEGylated mutant cocaine esterase (CocE) on the reinforcing and discriminative stimulus effects of cocaine in rats. Neuropsychopharmacology doi:10.1038/ npp.2011.226 (2011) (Epub ahead of print).
-
(2011)
Neuropsychopharmacology
-
-
Collins, G.T.1
Narasimhan, D.2
Cunningham, A.R.3
-
87
-
-
82555189761
-
Evaluation of the hydrolytic activity of a long-acting mutant bacterial cocaine in the presence of commonly co-administered drugs
-
Brim RL, Noon KR, Nichols J, Narasimhan D, Woods JH, Sunahara RK. Evaluation of the hydrolytic activity of a long-acting mutant bacterial cocaine in the presence of commonly co-administered drugs. Drug Alcohol Depend. 119(3), 224-228 (2011).
-
(2011)
Drug Alcohol Depend.
, vol.119
, Issue.3
, pp. 224-228
-
-
Brim, R.L.1
Noon, K.R.2
Nichols, J.3
Narasimhan, D.4
Woods, J.H.5
Sunahara, R.K.6
-
88
-
-
0028206320
-
Effects of dopamine D-1 and D-2 antagonists on cocaine self- administration under different schedules of reinforcement in the rat
-
Caine SB, Koob GF. Effects of dopamine D-1 and D-2 antagonists on cocaine self-administration under different schedules of reinforcement in the rat. J. Pharmacol. Exp. Ther. 270(1), 209-218 (1994). (Pubitemid 24229630)
-
(1994)
Journal of Pharmacology and Experimental Therapeutics
, vol.270
, Issue.1
, pp. 209-218
-
-
Caine, S.B.1
Koob, G.F.2
-
89
-
-
0030781787
-
Peripheral cocaine-blocking agents: New medications for cocaine dependence. An introduction to immunological and enzymatic approaches to treating cocaine dependence reported by Fox, Gorelick and Cohen in the immediately succeeding articles
-
DOI 10.1016/S0376-8716(97)00072-0, PII S0376871697000720
-
Sparenborg S, Vocci F, Zukin S. Peripheral cocaine-blocking agents: new medications for cocaine dependence. An introduction to immunological and enzymatic approaches to treating cocaine dependence reported by Fox, Gorelick and Cohen in the immediately succeeding articles (see pages 153-174). Drug Alcohol Depend. 48(3), 149-151 (1997). (Pubitemid 27526020)
-
(1997)
Drug and Alcohol Dependence
, vol.48
, Issue.3
, pp. 149-151
-
-
Sparenborg, S.1
Vocci, F.2
Zukin, S.3
-
90
-
-
0029983402
-
Cocaine and butyrylcholinesterase (BChE): Determination of enzymatic parameters
-
DOI 10.1016/0024-3205(96)00065-3
-
Mattes C, Bradley R, Slaughter E, Browne S. Cocaine and butyrylcholinesterase (BChE): determination of enzymatic parameters. Life Sci. 58(13), PL257-261 (1996). (Pubitemid 26086425)
-
(1996)
Life Sciences
, vol.58
, Issue.13
-
-
Mattes, C.E.1
Bradley, R.2
Slaughter, E.3
Browne, S.4
-
91
-
-
0032944436
-
An improved cocaine hydrolase: The A328Y mutant of human butyrylcholinesterase is 4-fold more efficient
-
Xie W, Altamirano CV, Bartels CF, Speirs RJ, Cashman JR, Lockridge O. An improved cocaine hydrolase: the A328Y mutant of human butyrylcholinesterase is 4-fold more efficient. Mol. Pharmacol. 55(1), 83-91 (1999). (Pubitemid 29042525)
-
(1999)
Molecular Pharmacology
, vol.55
, Issue.1
, pp. 83-91
-
-
Xie, W.1
Altamirano, C.V.2
Bartels, C.F.3
Speirs, R.J.4
Cashman, J.R.5
Lockridge, O.6
-
92
-
-
0034062037
-
Butyrylcholinesterase accelerates cocaine metabolism: In vitro and in vivo effects in nonhuman primates and humans
-
Carmona GN, Jufer RA, Goldberg SR et al. Butyrylcholinesterase accelerates cocaine metabolism: in vitro and in vivo effects in nonhuman primates and humans. Drug Metab. Dispos. 28(3), 367-371 (2000). (Pubitemid 30137064)
-
(2000)
Drug Metabolism and Disposition
, vol.28
, Issue.3
, pp. 367-371
-
-
Carmona, G.N.1
Jufer, R.A.2
Goldberg, S.R.3
Gorelick, D.A.4
Greig, N.H.5
Yu, Q.S.6
Cone, E.J.7
Schindler, C.W.8
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