Effects of cocaine hydrolase on cocaine self-administration under a PR schedule and during extended access (escalation) in rats

Psychopharmacology

Volumn 213, Issue 4, 2011, Pages 817-829

  Carroll, Marilyn E ^a   Gao, Yang ^b   Brimijoin, Stephen ^b   Anker, Justin J ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

Cocaine hydrolase; Cocaine self administration; Escalation; Maintenance; PR schedule; Rats

Indexed keywords

CHOLINESTERASE INHIBITOR; COCAINE; COCAINE HYDROLASE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG INHIBITION; DRUG SELF ADMINISTRATION; FEMALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SHORT COURSE THERAPY;

ANIMALS; BUTYRYLCHOLINESTERASE; COCAINE; FEMALE; HUMANS; RATS; RATS, WISTAR; REINFORCEMENT SCHEDULE; REWARD; SELF ADMINISTRATION;

EID: 79952490297     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-010-2040-3     Document Type: Article

References (40)

1. Ahmed SH, Koob GF (1998) Transition from moderate to excessive drug intake: change in hedonic set point. Science 282:298-300 (Pubitemid 28487203)
2. Ahmed SH, Koob GF (1999) Long-lasting increase in the set point for cocaine self-administration after escalation in rats. Psychopharmacology (Berl) 146:303-312 (Pubitemid 29480242)
3. Ahmed SH, Koob GF (2005) Transition to drug addiction: a negative reinforcement model based on an allostatic decrease in reward function. Psychopharmacology (Berl) 180:473-490 (Pubitemid 40905037)
4. Anker JJ, Perry JL, Gliddon LA, Carroll ME (2009) Impulsivity predicts the escalation of cocaine self-administration in rats. Pharmacol Biochem Behav 93:343-348
5. Anker JJ, Zlebnik NE, Carroll ME (2010) Differential effects of allopregnanolone on the escalation of cocaine self-administration and sucrose intake in female rats. Psychopharmacology 212(3):419-429
6. Bresler M, Rosser S, Basran A, Bruce N (2000) Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1. Appl Environ Microbiol 66:904-908 (Pubitemid 30130004)
7. Brimijoin S, Gao Y, Anker JJ, Gliddon LA, LaFleur D, Shah R, Zhao Q, Singh M, Carroll ME (2008) A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats. Neuropsychopharmacology 27:15-25
8. Carroll ME, Boe IN (1982) Increased intravenous drug self-administration during deprivation of other reinforcers. Pharmacol Biochem Behav 17:563-567 (Pubitemid 12037673)
9. Carroll ME, Batulis DA, Landry KL, Morgan AD (2005) Sex differences in the escalation of oral phencyclidine (PCP) self-administration under FR and PR schedules in rhesus monkeys. Psychopharmacology 180:414-426 (Pubitemid 40905031)
10. Collins GT, Brim RL, Narasimhan D, Ko MC, Sunahara RK, Zhan CG, Woods JH (2009) Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats. J Pharmacol Exp Ther 331:445-455
11. Cooper ZD, Narasimhan D, Sunahara RK, Mierrzejewski P, Jutkiewicz EM, Larsen NA, Wilson IA, Landry DW, Woods JH (2006) Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase. Mol Pharmacol 70:1885-1891 (Pubitemid 44771904)
12. Devlin RJ, Henry JA (2008) Clinical review: major consequences of illicit drug consumption. Crit Care 12:202
13. Dickerson TJ, Janda KD (2005) Recent advances for the treatment of cocaine abuse: central nervous system immunopharmacotherapy. AAPS J 7:E579-E586
14. Fitch TE, Roberts DC (1993) The effects f dose and access restrictions on the periodicity of cocaine self-administration in the rat. Drug Alcohol Depend 33:119-128 (Pubitemid 23286630)
15. Gao Y, Brimijoin S (2009) Lasting reduction of cocaine action in neostriatum - a hydrolase gene therapy approach. J Pharmacol Exp Ther 330:449-457
16. Gao Y, LaFleur D, Shah R, Zhao Q, Singh M, Brimijoin S (2008) An albumin-butyrylcholinesterase for cocaine toxicity and addiction: catalytic and pharmacokinetic properties. Chem-Biol Interact 175:83-87
17. Gorelick DA (2008) Pharmacokinetic approaches to treatment of drug addiction. Exp Rev Clin Pharmacol 1:277-290
18. Kalivas PW, Volkow ND (2005) The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatry 162:1403-1413 (Pubitemid 41105554)
19. Kitamura O, Wee S, Specio SE, Koob GF, Pulvirenti L (2006) Escalation of methamphetamine self-administration in rats: a dose-effect function. Psychopharmacology (Berl) 186:48-53 (Pubitemid 43668310)
20. Ko MC, Narasimhan D, Berlin A, Lukacs N, Sunahara R, Woods J (2009) Effects of cocaine esterase following its repeated administration with cocaine in mice. Drug Alcohol Depend 101:202-209
21. Larson EB, Anker JJ, Gliddon LA, Fons KS, Carroll ME (2007) Effects of estrogen and progesterone on the escalation of cocaine self-administration in female rats during extended access. Exp Clin Psychopharmacol 15:461-471 (Pubitemid 350102233)
22. Lenoir M, Ahmed SH (2008) Supply of a nondrug substitute reduces escalated heroin consumption. Neuropsychopharmacology 33:2272-2282 (Pubitemid 351992078)
23. Lynch WJ, Carroll ME (2001) Regulation of drug intake. Exp Clin Psychopharmacol 9:131-143 (Pubitemid 32852310)
24. Lynch WJ, Arizzi MN, Carroll ME (2000) Effects of sex and the estrous cycle on regulation of intravenously self-administered cocaine in rats. Psychopharmacology (Berl) 152:132-139
25. Morgan D, Roberts DC (2004) Sensitization to the reinforcing effects of cocaine following binge-abstinent self-administration. Neurosci Biobehav Rev 27:803-812 (Pubitemid 38199610)
26. Morgan AD, Campbell UC, Fons RD, Carroll ME (2002) Effects of agmatine on the escalation of intravenous cocaine an fentanyl self-administration in rats. Pharmacol Biochem Behav 72:873-880 (Pubitemid 34621314)
27. National Research Council (2003) Guidelines for the care and use of mammals in neuroscience and behavioral research. The National Academies, Washington DC, p 209
28. Pan Y, Gao D, Yang W, Cho H, Yang G, Tai HH, Zhan CG (2005) Computational redesign of human butyrylcholinesterase for anti-cocaine medication. Proc Natl Acad Sci U S A 102:16656-16661 (Pubitemid 41688832)
29. Pancook JD, Pecht G, Ader M, Mosko M, Lockridge O, Watkins JD (2003) Application of directed evolution technology to optimize the cocaine hydrolase activity of human butyrylcholinesterase. FASEB J 17:565
30. Paterson NE, Markou A (2003) Increased motivation for self-administered cocaine after escalated cocaine intake. NeuroReport 14:2229-2232
31. Perry JL, Dess NK, Morgan AD, Carroll ME (2006) Escalation of i.v. cocaine self-administration and reinstatement of cocaine-seeking behavior in rats selectively bred for high and low saccharin intake. Psychopharmacology 186:235-24
32. Roberts DCS, Bennett SA, Vickers GJ (1989) The estrous cycle affects cocaine self-administration on a progressive ratio schedule in rats. Psychopharmacology (Berl) 98:408-411 (Pubitemid 19162433)
33. Roth ME, Carroll ME (2004) Sex differences in the escalation of intravenous cocaine intake following long- or short-access to self-administration. Pharm Biochem Behav 78:199-207 (Pubitemid 38829354)
34. Sofuoglu M, Kosten TR (2005) Novel approaches to the treatment of cocaine addiction. CNS Drugs 19:13-25 (Pubitemid 40165154)
35. Specio SE, Wee S, O'Dell LE, Boutrel B, Zorrilla EP, Koob GF (2008) CRF(1) receptor antagonists attenuate escalated cocaine self-administration in rats. Psychopharmacology 196:473-482 (Pubitemid 351191180)
36. Substance Abuse and Mental Health Services Administration (SAMHSA) (2009) Results from the 2008 National Survey on Drug Use and Health: National Findings. Office of Applied Studies NSDUH Series H-32, DHHS Publication No. SMA 07-4293 SAMHSA, Rockville, MD
37. Sun H, El Yazal J, Brimijoin S, Pang Y-P (2001) Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase: engineering effective butyrylcholinesterase mutants for cocaine detoxification. J Biol Chem 276:9330-9336
38. Sun H, Pang YP, Lockridge O, Brimijoin S (2002) Re-engineering butyrylcholinesterase as a cocaine hydrolase. Mol Pharmacol 62:220-224 (Pubitemid 34804100)
39. Vocci FJ, Acri J, Elkashef A (2005) Medication development for addictive disorders: the state of the science. Am J Psychiatry 162:1432-1440 (Pubitemid 41105557)
40. Wee S, Mandymam CD, Lekic DM, Koob GF (2008) Noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access. Eur Neuropsychopharmacol 18:303-311 (Pubitemid 351246717)